A new noncanonical nuclear genetic code: Translation of UAA into glutamate

Current Biology

Volumn 13, Issue 5, 2003, Pages 442-447

  Sánchez Silva, Rocío ^a   Villalobo, Eduardo ^a   Morin, Loïc ^b   Torres, Antonio ^a  

^a UNIVERSITY OF SEVILLE   (Spain)

^b UNIVERSITÉ PARIS SACLAY   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ACTINS; AMINO ACID SEQUENCE; ANIMALS; CILIOPHORA; GENETIC CODE; GLUTAMIC ACID; MOLECULAR SEQUENCE DATA; PHYLOGENY; RNA, MESSENGER; RNA, TRANSFER, GLU; SEQUENCE ALIGNMENT; TUBULIN;

BLEPHARISMA AMERICANUM; CILIOPHORA; COLPODA; COLPODA INFLATA; EUPLOTES; MICROSTOMA; OLIGOHYMENOPHOREA; OPISTHONECTA HENNEGUYI; OPISTHONECTA MATIENSIS; OXYTRICHA; PARAMECIUM; PERITRICHIA; TETRAHYMENA; VORTICELLA; VORTICELLA MICROSTOMA;

EID: 0037418581     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(03)00126-X     Document Type: Article

References (15)

1. Knight, R.D., Freeland, S.J., and Landweber, L.F. (2001). Rewiring the keyboard: evolvability of the genetic code. Nat. Rev. Genet. 2, 49-58.
2. Meyer, F., Schmidt, H.J., Plumper, E., Hasilik, A., Mersmann, G., Meyer, H.E., Engstrom, A., and Heckmann, K. (1991). UGA is translated as cysteine in pheromone 3 of Euplotes octocarinatus. Proc. Natl. Acad. Sci. USA 88, 3758-3761.
3. Lozupone, C.A., Knight, R.D., and Landweber, L.F. (2001). The molecular basis of nuclear genetic code change in ciliates. Curr. Biol. 11, 65-74.
4. Maciejewski, J.J., Vacchiano, E.J., McCutcheon, S.M., and Buhse, H.E. (1999). Cloning and expression of a cDNA encoding a Vorticella convallaria spasmin: an EF-hand calcium-binding protein. J. Eukaryot. Microbiol. 46, 165-173.
5. Gln. EMBO J. 5, 1307-1311.
6. Lowe, T.M., and Eddy, S.R. (1997). tRNAscan-SE: a program for improved detection of transfer RNA genes in genomic sequence. Nucleic Acids Res. 25, 955-964.
7. Miao, W., Yu, Y.-H., and Shen, Y.-F. (2001). Phylogenetic relationships of the Subclass Peritrichia (Olygohymenophorea, Ciliophora) with emphasis on the genus Epistylis, inferred from small subunit rRNA gene sequences. J. Eukaryot. Microbiol. 48, 583-587.
8. Baroin Tourancheau, A., Villalobo, E., Tsao, N., Torres, A., and Pearlmann, E. (1998). Protein coding trees in ciliates: comparison with rRNA-based phylogenies. Mol. Phylogenet. Evol. 10, 299-309.
9. Perez-Romero, P., Villalobo, E., and Torres, A. (2001). Different stop codon usage in two pseudohypotrich ciliates. FEMS Microbiol. Lett. 205, 259-263.
10. Baroin Tourancheau, A., Tsao, N., Klobutcher, L.A., Pearlman, R.E., and Adoutte, A. (1995). Genetic code deviation in the ciliates: evidence for multiple and independent events. EMBO J. 14, 3262-3267.
11. Gln transamidation pathway among bacteria. A member of the alpha purple bacteria lacks glutaminyl-tRNA synthetase. J. Biol. Chem. 271, 14856-14863.
12. Siatecka, M., Rozek, M., Barciszewski, J., and Mirande, M. (1998). Modular evolution of the Glx-tRNA synthetase family. Rooting of the evolutionary tree between the bacteria and archaea/eukarya branches. Eur. J. Biochem. 256, 80-87.
13. Rogers, K.C., and Söll, D. (1995). Divergence of glutamate and glutamine aminoacylation pathways: providing the evolutionary rationale for mischarging. J. Mol. Evol. 40, 476-481.
14. Srinivasan, G., James, C.M., and Krzycki, J.A. (2002). Pyrrolysine encoded by UAG in Archaea: charging of a UAG-decoding specialized tRNA. Science 24, 1459-1462.
15. Ibba, M., and Söll, D. (2000). Aminoacyl-tRNA synthesis. Annu. Rev. Biochem. 69, 617-650.