Vasoreactions to acute hypoxia, whole lungs and isolated vessels compared: Modulation by NO

Respiratory Physiology and Neurobiology

Volumn 134, Issue 2, 2003, Pages 115-129

  Emery, C J ^a   Teng, G Q ^a   Liu, X ^a   Barer, G R ^a,b  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

^b NONE   (United Kingdom)

Author keywords

Hypoxia pulmonary vasoreaction, NO; Mammals, rat; Mediators, NO; Pulmonary circulation, hypoxia; Pulmonary circulation, pharmacological agents, L NAME

Indexed keywords

N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

ANIMAL TISSUE; ARTICLE; BRONCHODILATATION; CONTROLLED STUDY; DISEASE SEVERITY; HYPOXIA; IN VITRO STUDY; ISOLATED ORGAN; LUNG ARTERY PRESSURE; LUNG VASOCONSTRICTION; MODULATION; NONHUMAN; PRIORITY JOURNAL; PULMONARY HYPERTENSION; RAT; REDUCTION;

ANIMALS; ANOXIA; LUNG; MALE; MYOGRAPHY; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; POTASSIUM CHANNEL BLOCKERS; PULMONARY CIRCULATION; RATS; RATS, WISTAR; TIME FACTORS; VASOCONSTRICTION;

EID: 0037417090     PISSN: 15699048     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1569-9048(02)00213-6     Document Type: Article

References (56)

1. Archer S.L., Tolines J.P., Rau J.L., Weir E.K. Hypoxic vasoconstriction is enhanced by inhibition of the synthesis of an endothelium-derived relaxing factor. Biochem. Biophys. R. 164:1989;1198-1205.
2. Barer G.R. Reactivity of vessels of collapsed and ventilated lungs to drugs and hypoxia. Circ. Res. 18:1966;366-378.
3. Barer G.R., Howard P., Shaw J.W. Stimulus-response curves for the pulmonary vascular bed to hypoxia and hypercapnia. J. Physiol. (Lond.). 211:1970;139-155.
4. Barer G.R., Emery C.J., Stewart A., Bee D., Howard P. Endothelial control of the pulmonary circulation in normal and chronically hypoxic rats. J. Physiol. (Lond.). 463:1993;1-16.
5. Bee D., Emery C.J., Howard P. An analysis of the action of an analogue of almitrine bismesylate in the rat model of hypoxic lung disease. Exp. Physiol. 77:1992;819-828.
6. Bennie R.E., Packer S.D., Powell R., Rhoades R.A. Biphasic response of pulmonary artery to hypoxia. Am. J. Physiol. 261:1991;L156-L163.
7. Clementi E., Brown G.C., Foxwell N., Moncada S. On the mechanism whereby vascular endothelial cells regulate their oxygen consumption. Proc. Natl. Acad. Sci. USA. 96:1999;1559-1562.
8. Demiryurek A.T., Wadsworth R.M., Kane K.A. Effect of hypoxia on isolated intrapulmonary arteries from sheep. Pulm. Pharmacol. 4:1991;158-164.
9. Demiryurek A.T., Wadsworth R.M., Kane K.A. Pharmacological evidence for the role of mediators in hypoxia-induced vasoconstriction in sheep intrapulmonary artery rings. Eur. J. Pharmacol. 203:1991;1-8.
10. Demiryurek A.T., Wadsworth R.M., Kane K.A., Peacock A.J. The role of endothelium in hypoxic contraction of human pulmonary artery rings. Am. Rev. Resp. Dis. 147:1993;283-290.
11. Dipp M., Nye P.C.G., Evans A.M. Hypoxic release of calcium from the sarcoplasmic reticulum of pulmonary artery smooth muscle. Am. J. Physiol. 281:2001;L318-L325.
12. Dipp P.M., Evans A.M. Cyclic ADP-ribose is the primary trigger for hypoxic pulmonary vasoconstriction in the rat lung in situ. Circ. Res. 89:2001;77-83.
13. Dirken M.N.K., Heemstra H. Alveolar oxygen tension and lung circulation. Q. J. Exp. Physiol. 34:1948;1193-1211.
14. Dorrington K.L., Clar C., Young J.D., Jonas M., Tansley J.G., Robbins P.A. Time course of the human pulmonary vascular response to 8 hours of isocapnic hypoxia. Am. J. Physiol. 273:1997;H1126-H1134.
15. Emery C.J., Bee D., Barer G.R. Mechanical properties and reactivity in isolated lungs of chronically hypoxic rats. Clin. Sci. Mol. Med. 61:1981;580-589.
16. von Euler U.S., Liljestrand I.G. Observations on the pulmonary arterial blood pressure in the cat. Acta Physiol. Scand. 14:1946;120-135.
17. Greenberg B., Kishiyama S. Endothelium-independent response to severe hypoxia in rat pulmonary artery. Am. J. Physiol. 265:1993;H1712-H1720.
18. Hampl V., Archer S.L., Nelson D.P., Weir E.K. Chronic EDRF inhibition and hypoxia: effects on pulmonary circulation and systemic pressure. J. Appl. Physiol. 75:1993;1745-1757.
19. Hampl V., Herget J. Role of nitric oxide in the pathogenesis of pulmonary hypertension. Physiol. Rev. 80:2000;1337-1372.
20. Hasunuma K., Yamaguchi T., Rodman D.M., O'Brien R.F., McMurtry I.F. Effects of inhibitors of EDRF and EDHF. Am. J. Physiol. 260:1991;L97-L104.
21. Herget J., Palecek F. Pulmonary artery blood pressure in closed chest rats. Arch. Int. Pharmacodyn. Ther. 198:1972;107-117.
22. Higenbottam T.W. Endothelial dysfunction providing the basis for the treatment of pulmonary hypertension. Chest. 114:1998;72S-79S.
23. Isaacson T.C., Hampl V., Weir E.K., Nelson D.P., Archer S.L. Increased endothelium-derived NO in pulmonary circulation of chronically hypoxic rats. J. Appl. Physiol. 76:1994;933-940.
24. Jin N., Packer C.S., Rhoades R.A. Pulmonary arterial hypoxic contraction: signal transduction. Am. J. Physiol. 263:1992;L73-L78.
25. Johns R.A., Linden J.M., Peach M.J. Endothelium-dependent relaxation and cyclic GMP accumulation in rabbit pulmonary artery are selectively impaired by moderate hypoxia. Circ. Res. 65:1989;1508-1515.
26. Kovitz K.L., Aleskowich T.D., Sylvester J.T., Flanaghan A. Endothelium-derived contracting and dilating factors contribute to hypoxic responses of pulmonary arteries. Am. J. Physiol. 263:1993;H1139-H1148.
27. Leach R.M., Robertson T.P., Twort C.H.C., Ward J.P.T. Hypoxic vasoconstriction in rat pulmonary and mesenteric arteries. Am. J. Physiol. 266:1994;L223-L231.
28. Leach, R.M., Hill, H.S., Ward, J.P.T., 1998. The role of glucolysis in hypoxic pulmonary artery constriction, HPV. Thorax S4, S52.
29. LeCras T.D., McMurtry I.F. Nitric oxide production in the hypoxic lung. Am. J. Physiol. 280:2001;L575-L582.
30. Liu Q., Sham J.S.K., Shimoda L.A., Sylvester J.T. Hypoxic constriction of porcine distal pulmonary arteries: endothelium and endothelin dependent. Am. J. Physiol. 280:2001;L856-L865.
31. Madden J.A., Vadula M.S., Kurup V.P. Effects of hypoxia and other vasoconstrictor agents on pulmonary and cerebral smooth muscle cells. Am. J. Physiol. 263:1992;L384-L393.
32. McMurtry I.F., Petrun M.D., Reeves J. Lungs from chronically hypoxic rats have decreased pressure response to acute hypoxia. Am. J. Physiol. 235:1978;H104-H109.
33. Mulvaney M.J., Halpern W. Contractile properties of small arterial resistance vessels in spontaneously hypertensive and normotensive rats. Circ. Res. 41:1977;19-25.
34. Ogata M., Ohe M., Katayose D., Takashima T. Modulatory role of EDRF in hypoxic contraction of porcine pulmonary arteries. Am. J. Physiol. 262:1992;H691-H697.
35. Ohe M., Ogata M., Katayose D., Takashima T. Hypoxic contraction of prestretched human pulmonary arteries. Resp. Physiol. 87:1992;105-114.
36. Oka M., Hasunuma K.K., Steltzer T.J., Rodman D.M., McMurtry I.F. Endothelium-derived relaxant factor suppresses an unidentified constrictor in hypertensive rat lungs. Am. J. Physiol. 264:1993;L587-L597.
37. 2 responses in calf pulmonary arteries. Am. J. Physiol. 262:1992;L560-L565.
38. Osaki M., Marshall C., Amaki Y., Marshall B.E. Role of wall tension in hypoxic responses of isolated rat pulmonary arteries. Am. J. Physiol. 275:1998;L1069-L1077.
39. Pearson P.J., Lin P.J., Evora P.R.B., Schaff H.V. Endothelium-dependent response of human internal mammary to hypoxia. Am. J. Physiol. 264:1993;H376-H380.
40. Robertson B.E., Warren J.B.E., Nye P.J.C. Inhibition of NO synthase potentiates hypoxic vasoconstriction in rat lungs. Exp. Physiol. 75:1990;255-257.
41. ++-sensitising vasoconstrictor from the perfused rat lung. Cardiovasc. Res. 50:2001;145-150.
42. Rodman D.H., Yamaguchi T., O'Brien R.F., McMurtry I.F. Hypoxic contraction of isolated rat pulmonary artery. J. Pharm. Exp. Ther. 248:1989;952-959.
43. Rodman D.H., Yamaguchi T., Hasunuma K., O'Brien R.F., McMurtry I.F. Effects of hypoxia on endothelium-dependent relaxation of pulmonary artery. Am. J. Physiol. 258:1990;L207-L214.
44. Rogers T.K., Stewart A.G., Morice A.H. Effect of chronic hypoxia on rat pulmonary resistance vessels: vasodilatation by atrial natriuretic factor. Clin. Sci. 83:1992;723-729.
45. Sole M.J., Dromak M., Schwarz L., Hussein M.V., Vaughan-Neil E.F. The extraction of circulating catecholamines by the lung of normal man and patients with pulmonary hypertension. Circulation. 60:1979;160-163.
46. Suggett A.J., Mohammed F.W., Barer G.R., Twelves C., Bee D. Quantitative analysis of hypoxic vasoconstriction in the ferret lung. Resp. Physiol. 48:1981;89-104.
47. Teng G.Q., Barer G.R. Relaxation of small renal arteries in hypoxia: reduced relaxation in chronically hypoxic compared with normal rats. Clin. Sci. 84:1993;31P.
48. Teng G.Q., Barer G.R. In vitro responses of lung arteries to acute hypoxia after NO synthase blockade or chronic hypoxia. J. Appl. Physiol. 79:1995;763-770.
49. Teng G.Q., Barer G.R. Hypoxic pulmonary vasoconstriction/ dilatation is modified by different preconditions. Thorax. 50:1995;452P.
50. Twaddle J.L.T., Xia N., Nye P.C.G. Stimulus-response relation for the second phase hypoxic constriction of the small isolated pulmonary artery of the rat. J. Physiol. 491:1996;50P.
51. Vejlstrup N.G., O'Neill M., Nagyova B., Dorrington K.L. Time course of hypoxic pulmonary vasoconstriction: a rabbit model of regional hypoxia. Am. J. Crit. Care Med. 155:1997;216-221.
52. Ward J.P.T., Robertson T.P. The role of the endothelium in hypoxic pulmonary vasoconstriction. Exp. Physiol. 80:1995;793-801.
53. Ward J.P.T., Aaronson P.I. Mechanisms of hypoxic vasoconstriction: can anyone be right? Resp. Physiol. 115:1999;261-271.
54. Wiener C.M., Sylvester J.T. Effects of glucose on hypoxic vasoconstriction in isolated ferret lungs. J. Appl. Physiol. 70:1991;439-446.
55. + channels modulate vasoconstrictor responses to severe hypoxia in isolated ferret lungs. J. Clin. Invest. 88:1991;500-504.
56. Wiener C.M., Banta M.R., Dowless M.S., Flavahan N.A., Sylvester J.T. Mechanisms of hypoxic dilatation in ferret pulmonary arteries. Am. J. Physiol. 269:1995;L351-L357.