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ChemBioChem

Volumn 4, Issue 1, 2003, Pages 90-95

Novel trifluoromethyl ketones as potent gastric lipase inhibitors

(3) Kokotos, George a Kotsovolou, Stavroula a Verger, Robert b

a UNIVERSITY OF ATHENS (Greece)

b Centre National de la Recherche Scientifique (France)

Author keywords

Enzymes; Inhibitors; Ketones; Lipases; Monolayers

Indexed keywords

5,5,5 TRIFLUORO 1 (DODECYLOXYMETHYL) 4 OXOPENTYL DECANOATE; CARBONYL DERIVATIVE; DECANOIC ACID DERIVATIVE; HYDROXYL GROUP; KETONE DERIVATIVE; LIPASE INHIBITOR; TRIACYLGLYCEROL LIPASE; TRIFLUOROMETHYL KETONE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL BOND; CHEMICAL STRUCTURE; ENZYME ACTIVITY; ESTERIFICATION; HUMAN; LIPOLYSIS; PRIORITY JOURNAL; SYNTHESIS;

ENZYME INHIBITORS; HYDROCARBONS, FLUORINATED; INDICATORS AND REAGENTS; KETONES; KINETICS; LIPASE; MAGNETIC RESONANCE SPECTROSCOPY; MEMBRANES, ARTIFICIAL; STOMACH; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY; TRIGLYCERIDES;

TRIFLUORO;

EID: 0037415046 PISSN: 14394227 EISSN: None Source Type: Journal
DOI: 10.1002/cbic.200390019 Document Type: Article

Times cited : (8)

References (32)

1
- 0001218601
- a) R. D. Schmid, R. Verger, Angew. Chem. 1998, 112, 1694-1720; Angew. Chem. Int. Ed. 1998, 37, 1608-1633;
- (1998) Angew. Chem. , vol.112 , pp. 1694-1720
- Schmid, R.D.¹ Verger, R.²

2
- 0032479388
- a) R. D. Schmid, R. Verger, Angew. Chem. 1998, 112, 1694-1720; Angew. Chem. Int. Ed. 1998, 37, 1608-1633;
- (1998) Angew. Chem. Int. Ed. , vol.37 , pp. 1608-1633

3
- 0003610122
- Wiley-VCH, Weinhelm
- b) U. T. Bornsheurer, R. J. Kazlauskas, Hydrolases in Organic Synthesis, Wiley-VCH, Weinhelm, 1999;
- (1999) Hydrolases in Organic Synthesis
- Bornsheurer, U.T.¹ Kazlauskas, R.J.²

4
- 0000967439
- c) M. T. Reetz, S. Wilensek, D. Zha, K.-E. Jaeger, Angew. Chem. 2001, 113, 3701-3703; Angew. Chem. Int. Ed. 2001, 40, 3589-3591.
- (2001) Angew. Chem. , vol.113 , pp. 3701-3703
- Reetz, M.T.¹ Wilensek, S.² Zha, D.³ Jaeger, K.-E.⁴

5
- 0035477024
- c) M. T. Reetz, S. Wilensek, D. Zha, K.-E. Jaeger, Angew. Chem. 2001, 113, 3701-3703; Angew. Chem. Int. Ed. 2001, 40, 3589-3591.
- (2001) Angew. Chem. Int. Ed. , vol.40 , pp. 3589-3591

6
- 0027250231
- a) F. Carrière, J. A. Barrowman, R. Verger, R. Laugier, Gastroenterology 1993, 105, 876-888;
- (1993) Gastroenterology , vol.105 , pp. 876-888
- Carrière, F.¹ Barrowman, J.A.² Verger, R.³ Laugier, R.⁴

7
- 0033774356
- b) F. Carrière, C. Renou, V. Lopez, J. De Caro, F. Ferrato, H. Lengsfeld, A. De Caro, R. Laugier, R. Verger, Gastroenterology 2000, 119, 949-960.
- (2000) Gastroenterology , vol.119 , pp. 949-960
- Carrière, F.¹ Renou, C.² Lopez, V.³ De Caro, J.⁴ Ferrato, F.⁵ Lengsfeld, H.⁶ De Caro, A.⁷ Laugier, R.⁸ Verger, R.⁹

8
- 0026604775
- a) J. B. Hauptman, F. S. Jeunet, D. Hartmann, Am. J. Clin. Nutr. 1992, 55, 309-313;
- (1992) Am. J. Clin. Nutr. , vol.55 , pp. 309-313
- Hauptman, J.B.¹ Jeunet, F.S.² Hartmann, D.³

9
- 0034095342
- b) N. Finer, W. P. T. James, P. G. Kopelman, M. E. J. Lean, G. Williams, Int. J. Obes. 2000, 24, 306-313.
- (2000) Int. J. Obes. , vol.24 , pp. 306-313
- Finer, N.¹ James, W.P.T.² Kopelman, P.G.³ Lean, M.E.J.⁴ Williams, G.⁵

10
- 0031556926
- a) Y. Gargouri, S. Ransac, R. Verger, Biochim. Biophys. Acta 1997, 1344, 6-37;
- (1997) Biochim. Biophys. Acta , vol.1344 , pp. 6-37
- Gargouri, Y.¹ Ransac, S.² Verger, R.³

11
- 0033802609
- b) J.-F. Cavalier, G. Buono, R. Verger, Acc. Chem. Res. 2000, 33, 579-589.
- (2000) Acc. Chem. Res. , vol.33 , pp. 579-589
- Cavalier, J.-F.¹ Buono, G.² Verger, R.³

12
- 0029161231
- a) M.-P. Egloff, F. Marguet, G. Buono, R. Verger, C. Cambillau, H. vanTilbeurgh, Biochemistry 1995, 34, 2751-2762;
- (1995) Biochemistry , vol.34 , pp. 2751-2762
- Egloff, M.-P.¹ Marguet, F.² Buono, G.³ Verger, R.⁴ Cambillau, C.⁵ VanTilbeurgh, H.⁶

13
- 0033546322
- b) A. Roussel, S. Canaan, M.-P. Egloff, M. Riviere, L. Dupuis, R. Verger, C. Cambillau, J. Biol. Chem. 1999, 274, 16995-17002.
- (1999) J. Biol. Chem. , vol.274 , pp. 16995-17002
- Roussel, A.¹ Canaan, S.² Egloff, M.-P.³ Riviere, M.⁴ Dupuis, L.⁵ Verger, R.⁶ Cambillau, C.⁷

14
- 0034628223
- a) A. Chiou, T. Markidis, V. Constantinou-Kokotou, R. Verger, G. Kokotos, Org. Lett. 2000, 2, 347-350;
- (2000) Org. Lett. , vol.2 , pp. 347-350
- Chiou, A.¹ Markidis, T.² Constantinou-Kokotou, V.³ Verger, R.⁴ Kokotos, G.⁵

15
- 0034976053
- b) A. Chiou, R. Verger, G. Kokotos, Lipids 2001, 36, 535-542.
- (2001) Lipids , vol.36 , pp. 535-542
- Chiou, A.¹ Verger, R.² Kokotos, G.³

16
- 0034680520
- a) G. Kokotos, R. Verger, A. Chiou, Chem. Eur. J. 2000, 6, 4211-4217;
- (2000) Chem. Eur. J. , vol.6 , pp. 4211-4217
- Kokotos, G.¹ Verger, R.² Chiou, A.³

17
- 0035830521
- b) S. Kotsovolou, A. Chiou, R. Verger, G. Kokotos, J. Org. Chem. 2001, 66, 962-967.
- (2001) J. Org. Chem. , vol.66 , pp. 962-967
- Kotsovolou, S.¹ Chiou, A.² Verger, R.³ Kokotos, G.⁴

18
- 0034628448
- D. Leung, G. Abbenante, D. P. Fairlie, J. Med. Chem. 2000, 43, 305-341.
- (2000) J. Med. Chem. , vol.43 , pp. 305-341
- Leung, D.¹ Abbenante, G.² Fairlie, D.P.³

19
- 0034739463
- D. A. Six, E. A. Dennis, Biochim. Biophys. Acta 2000, 1488, 1-19.
- (2000) Biochim. Biophys. Acta , vol.1488 , pp. 1-19
- Six, D.A.¹ Dennis, E.A.²

20
- 0028985263
- a) E. J. Ackermann, K. Conde-Frieboes, E. A. Dennis, J. Biol. Chem. 1995, 270, 445-450;
- (1995) J. Biol. Chem. , vol.270 , pp. 445-450
- Ackermann, E.J.¹ Conde-Frieboes, K.² Dennis, E.A.³

21
- 0032794186
- b) F. Ghomashchi, R. Loo, J. Balsinde, F. Bartoli, R. Apitz-Castro, J. D. Clark, E. A. Dennis, M. H. Gelb, Biochim. Biophys. Acta 1999, 1420, 45-56.
- (1999) Biochim. Biophys. Acta , vol.1420 , pp. 45-56
- Ghomashchi, F.¹ Loo, R.² Balsinde, J.³ Bartoli, F.⁴ Apitz-Castro, R.⁵ Clark, J.D.⁶ Dennis, E.A.⁷ Gelb, M.H.⁸

22
- 0000873581
- B. Neises, W. Steglich, Angew. Chem. 1978, 17, 556-557; Angew. Chem. Int. Ed. Engl. 1978, 17, 522-524.
- (1978) Angew. Chem , vol.17 , pp. 556-557
- Neises, B.¹ Steglich, W.²

23
- 84985520823
- B. Neises, W. Steglich, Angew. Chem. 1978, 17, 556-557; Angew. Chem. Int. Ed. Engl. 1978, 17, 522-524.
- (1978) Angew. Chem. Int. Ed. Engl. , vol.17 , pp. 522-524

24
- 0026669060
- M. R. Leanna, T. J. Sowin, H. E. Morton, Tetrahedron Lett. 1992, 33, 5029-5032.
- (1992) Tetrahedron Lett. , vol.33 , pp. 5029-5032
- Leanna, M.R.¹ Sowin, T.J.² Morton, H.E.³

25
- 0028901639
- J. Boivin, L. El Kaim, S. Z. Zard, Tetrahedron 1995, 51, 2573-2584.
- (1995) Tetrahedron , vol.51 , pp. 2573-2584
- Boivin, J.¹ El Kaim, L.² Zard, S.Z.³

26
- 0015576657
- a) R. Verger, G. H. de Haas, Chem. Phys. Lipids 1973, 10, 127-136;
- (1973) Chem. Phys. Lipids , vol.10 , pp. 127-136
- Verger, R.¹ De Haas, G.H.²

27
- 0030886501
- b) S. Ransac, M. G. Ivanova, R. Verger, I. Panaitov, Methods Enzymol. 1997, 286, 263-292.
- (1997) Methods Enzymol. , vol.286 , pp. 263-292
- Ransac, S.¹ Ivanova, M.G.² Verger, R.³ Panaitov, I.⁴

28
- 0026039544
- S. Ransac, Y. Gargouri, H. Moreau, R. Verger, Eur. J. Biochem. 1991, 202, 395-400.
- (1991) Eur. J. Biochem. , vol.202 , pp. 395-400
- Ransac, S.¹ Gargouri, Y.² Moreau, H.³ Verger, R.⁴

29
- 37049149750
- R. J. Howe, T. Malkin, J. Chem. Soc. 1951, 2663-2667.
- (1951) J. Chem. Soc. , pp. 2663-2667
- Howe, R.J.¹ Malkin, T.²

30
- 84986660091
- F. Bauer, K.-P. Ruess, M. Lieflaender, Liebigs Ann. Chem. 1991, 765-768.
- (1991) Liebigs Ann. Chem. , pp. 765-768
- Bauer, F.¹ Ruess, K.-P.² Lieflaender, M.³

31
- 0002071052
- H. C. Berk, K. E. Zwickelmaier, J. E. Franz, Synth. Commun. 1985, 15, 57-60.
- (1985) Synth. Commun. , vol.15 , pp. 57-60
- Berk, H.C.¹ Zwickelmaier, K.E.² Franz, J.E.³

32
- 0014294731
- F. Paltauf, F. Spencer, Chem. Phys. Lipids 1968, 2, 168-172.
- (1968) Chem. Phys. Lipids , vol.2 , pp. 168-172
- Paltauf, F.¹ Spencer, F.²

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