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Volumn 971, Issue 1, 2003, Pages 73-82

Long-term sensitization of primary afferents in adult rats exposed to neonatal colon pain

Author keywords

Chronic visceral hypersensitivity; Colorectal distension; Irritable bowel syndrome; Neonate rat; Pain; Primary afferent

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CENTRAL NERVOUS SYSTEM; CHRONIC PAIN; COLON; COLON DILATATION; CONTROLLED STUDY; DORSAL ROOT; IRRITABLE COLON; LUMBOSACRAL SPINE; MALE; NERVE PROJECTION; NERVE STIMULATION; NEWBORN; NOCICEPTION; NONHUMAN; PAIN ASSESSMENT; PAIN THRESHOLD; PERIPHERAL NERVOUS SYSTEM; PRIORITY JOURNAL; RAT; SENSITIZATION; SENSORY NERVE; THORACOLUMBAR SPINE; VISCERAL PAIN;

EID: 0037414419     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(03)02358-8     Document Type: Article
Times cited : (105)

References (57)
  • 1
    • 0032859566 scopus 로고    scopus 로고
    • Comparative study of viscerosomatic input onto postsynaptic dorsal column and spinothalamic tract neurons in the primate
    • Al-Chaer E.D., Feng Y., Willis W.D. Comparative study of viscerosomatic input onto postsynaptic dorsal column and spinothalamic tract neurons in the primate. J. Neurophysiol. 82:1999;1876-1882.
    • (1999) J. Neurophysiol. , vol.82 , pp. 1876-1882
    • Al-Chaer, E.D.1    Feng, Y.2    Willis, W.D.3
  • 2
    • 0034321927 scopus 로고    scopus 로고
    • A new model of chronic visceral hypersensitivity in adult rats induced by colon irritation during postnatal development
    • Al-Chaer E.D., Kawasaki M., Pasricha P.J. A new model of chronic visceral hypersensitivity in adult rats induced by colon irritation during postnatal development. Gastroenterology. 119:2000;1276-1285.
    • (2000) Gastroenterology , vol.119 , pp. 1276-1285
    • Al-Chaer, E.D.1    Kawasaki, M.2    Pasricha, P.J.3
  • 3
    • 0029998095 scopus 로고    scopus 로고
    • Pelvic visceral input into the nucleus gracilis is largely mediated by the postsynaptic dorsal column pathway
    • Al-Chaer E.D., Lawand N.B., Westlund K.N., Willis W.D. Pelvic visceral input into the nucleus gracilis is largely mediated by the postsynaptic dorsal column pathway. J. Neurophysiol. 76:1996;2675-2690.
    • (1996) J. Neurophysiol. , vol.76 , pp. 2675-2690
    • Al-Chaer, E.D.1    Lawand, N.B.2    Westlund, K.N.3    Willis, W.D.4
  • 4
    • 0036220604 scopus 로고    scopus 로고
    • Biological basis of visceral pain: Recent developments
    • Al-Chaer E.D., Traub R.J. Biological basis of visceral pain: recent developments. Pain. 96:2002;221-225.
    • (2002) Pain , vol.96 , pp. 221-225
    • Al-Chaer, E.D.1    Traub, R.J.2
  • 5
    • 0030732988 scopus 로고    scopus 로고
    • Sensitization of postsynaptic dorsal column neuronal responses by colon inflammation
    • Al-Chaer E.D., Westlund K.N., Willis W.D. Sensitization of postsynaptic dorsal column neuronal responses by colon inflammation. Neuroreport. 8:1997;3267-3273.
    • (1997) Neuroreport , vol.8 , pp. 3267-3273
    • Al-Chaer, E.D.1    Westlund, K.N.2    Willis, W.D.3
  • 7
    • 0033973737 scopus 로고    scopus 로고
    • Can adverse neonatal experiences alter brain development and subsequent behavior?
    • Anand K.J., Scalzo F.M. Can adverse neonatal experiences alter brain development and subsequent behavior? Biol. Neonate. 77:2000;69-82.
    • (2000) Biol. Neonate , vol.77 , pp. 69-82
    • Anand, K.J.1    Scalzo, F.M.2
  • 8
    • 0023037943 scopus 로고
    • Discharge properties of mechanosensitive afferents supplying the retroperitoneal space
    • Bahns E., Ernsberger U., Janig W., Nelke A. Discharge properties of mechanosensitive afferents supplying the retroperitoneal space. Pflugers Arch. 407:1986;519-525.
    • (1986) Pflugers Arch. , vol.407 , pp. 519-525
    • Bahns, E.1    Ernsberger, U.2    Janig, W.3    Nelke, A.4
  • 9
    • 0023038822 scopus 로고
    • Functional characteristics of lumbar visceral afferent fibres from the urinary bladder and the urethra in the cat
    • Bahns E., Ernsberger U., Janig W., Nelke A. Functional characteristics of lumbar visceral afferent fibres from the urinary bladder and the urethra in the cat. Pflugers Arch. 407:1986;510-518.
    • (1986) Pflugers Arch. , vol.407 , pp. 510-518
    • Bahns, E.1    Ernsberger, U.2    Janig, W.3    Nelke, A.4
  • 10
    • 0020535015 scopus 로고
    • Encoding of visceral noxious stimuli in the discharge patterns of visceral afferent fibres from the colon
    • Blumberg H., Haupt P., Janig W., Kohler W. Encoding of visceral noxious stimuli in the discharge patterns of visceral afferent fibres from the colon. Pflugers Arch. 398:1983;33-40.
    • (1983) Pflugers Arch. , vol.398 , pp. 33-40
    • Blumberg, H.1    Haupt, P.2    Janig, W.3    Kohler, W.4
  • 11
    • 0032553460 scopus 로고    scopus 로고
    • The onset of diffuse noxious inhibitory controls in postnatal rat pups: A C-Fos study
    • Boucher T., Jennings E., Fitzgerald M. The onset of diffuse noxious inhibitory controls in postnatal rat pups: a C-Fos study. Neurosci Lett. 257:1998;9-12.
    • (1998) Neurosci Lett. , vol.257 , pp. 9-12
    • Boucher, T.1    Jennings, E.2    Fitzgerald, M.3
  • 12
    • 0029076498 scopus 로고
    • Visceral pain: Mechanisms of peripheral and central sensitization
    • Cervero F. Visceral pain: Mechanisms of peripheral and central sensitization. Ann. Med. 27:1995;235-239.
    • (1995) Ann. Med. , vol.27 , pp. 235-239
    • Cervero, F.1
  • 13
    • 0024317162 scopus 로고
    • Mechanically evoked responses of afferent fibers innervating the guinea-pig's ureter: An in vitro study
    • Cervero F., Sann H. Mechanically evoked responses of afferent fibers innervating the guinea-pig's ureter: an in vitro study. J. Physiol. 412:1989;245-266.
    • (1989) J. Physiol. , vol.412 , pp. 245-266
    • Cervero, F.1    Sann, H.2
  • 14
    • 0034589730 scopus 로고    scopus 로고
    • Role of sensitized pelvic nerve afferents from the inflamed rat colon in the maintenance of visceral hyperalgesia
    • J. Sandkuhler, B. Bromm, Gebhart G.F. Elsevier Science BV
    • Coutinho S.V., Su X., Sengupta J.N., Gebhart G.F. Role of sensitized pelvic nerve afferents from the inflamed rat colon in the maintenance of visceral hyperalgesia. Sandkuhler J., Bromm B., Gebhart G.F. Progress in Brain Research. Vol. 129:2000;375-387 Elsevier Science BV.
    • (2000) Progress in Brain Research , vol.129 , pp. 375-387
    • Coutinho, S.V.1    Su, X.2    Sengupta, J.N.3    Gebhart, G.F.4
  • 16
    • 0030900827 scopus 로고    scopus 로고
    • Irritable bowel syndrome: A technical review for practice guideline development
    • Drossman D.A., Whitehead W.E., Camilleri M. Irritable bowel syndrome: a technical review for practice guideline development. Gastroenterology. 112:1997;2120-2137.
    • (1997) Gastroenterology , vol.112 , pp. 2120-2137
    • Drossman, D.A.1    Whitehead, W.E.2    Camilleri, M.3
  • 17
    • 0034998005 scopus 로고    scopus 로고
    • The neurobiology of pain: Developmental aspects
    • Fitzgerald M., Beggs S. The neurobiology of pain: developmental aspects. Neuroscientist. 7:2001;246-257.
    • (2001) Neuroscientist , vol.7 , pp. 246-257
    • Fitzgerald, M.1    Beggs, S.2
  • 18
    • 0033529210 scopus 로고    scopus 로고
    • The postnatal development of spinal sensory processing
    • Fitzgerald M., Jennings E. The postnatal development of spinal sensory processing. Proc. Natl. Acad. Sci. USA. 96:1999;7719-7722.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 7719-7722
    • Fitzgerald, M.1    Jennings, E.2
  • 19
    • 0022656631 scopus 로고
    • The functional development of descending inhibitory pathways in the dorsolateral funiculus of the newborn rat spinal cord
    • Fitzgerald M., Koltzenburg M. The functional development of descending inhibitory pathways in the dorsolateral funiculus of the newborn rat spinal cord. Brain Res. 389:1986;261-270.
    • (1986) Brain Res. , vol.389 , pp. 261-270
    • Fitzgerald, M.1    Koltzenburg, M.2
  • 20
    • 0033730210 scopus 로고    scopus 로고
    • Lecture-2000: Physiology, pathophysiology, and pharmacology of visceral pain
    • Gebhart G.F., Bonica J.J. Lecture-2000: Physiology, pathophysiology, and pharmacology of visceral pain. Reg. Anesth. Pain Med. 25:2000;632-638.
    • (2000) Reg. Anesth. Pain Med. , vol.25 , pp. 632-638
    • Gebhart, G.F.1    Bonica, J.J.2
  • 21
    • 0033935566 scopus 로고    scopus 로고
    • Pathobiology of visceral pain: Molecular mechanisms and therapeutic implications IV. Visceral afferent contributions to the pathobiology of visceral pain
    • Gebhart G.F. Pathobiology of visceral pain: molecular mechanisms and therapeutic implications IV. Visceral afferent contributions to the pathobiology of visceral pain. Am. J. Physiol. 278:2000;G834-G838.
    • (2000) Am. J. Physiol. , vol.278
    • Gebhart, G.F.1
  • 22
    • 17144455087 scopus 로고    scopus 로고
    • Visceral pain-peripheral sensitisation
    • discussion iv 58
    • G.F. Gebhart, Visceral pain-peripheral sensitisation, Gut, 47(Suppl. 4: iv 54-5; discussion iv 58) (2000).
    • (2000) Gut , vol.47 , Issue.SUPPL. 4 , pp. 54-55
    • Gebhart, G.F.1
  • 24
    • 0025371109 scopus 로고
    • Activation of unmyelinated afferent fibers by mechanical stimuli and inflammation of the urinary bladder in the cat
    • Habler H.J., Janig W., Koltzenburg M. Activation of unmyelinated afferent fibers by mechanical stimuli and inflammation of the urinary bladder in the cat. J. Physiol. 425:1990;545-562.
    • (1990) J. Physiol. , vol.425 , pp. 545-562
    • Habler, H.J.1    Janig, W.2    Koltzenburg, M.3
  • 27
    • 0019949510 scopus 로고
    • An analysis of axon populations in the nerves to pelvic viscera in the rat
    • Hulsebosch C.E., E Coggeshall R. An analysis of axon populations in the nerves to pelvic viscera in the rat. J. Comp. Neurol. 211:1982;1-10.
    • (1982) J. Comp. Neurol. , vol.211 , pp. 1-10
    • Hulsebosch, C.E.1    E Coggeshall, R.2
  • 28
    • 0024994606 scopus 로고
    • On the function of spinal primary afferent fibers supplying colon and urinary bladder
    • Janig W., Koltzenburg M. On the function of spinal primary afferent fibers supplying colon and urinary bladder. J. Auton. Nerv. Syst. 30:1990;s89-s96.
    • (1990) J. Auton. Nerv. Syst. , vol.30
    • Janig, W.1    Koltzenburg, M.2
  • 29
    • 0025773824 scopus 로고
    • Receptive properties of sacral primary afferent neurons supplying the colon
    • Janig W., Koltzenburg M. Receptive properties of sacral primary afferent neurons supplying the colon. J. Neurophysiol. 65:1991;1067-1077.
    • (1991) J. Neurophysiol. , vol.65 , pp. 1067-1077
    • Janig, W.1    Koltzenburg, M.2
  • 30
    • 0022964524 scopus 로고
    • Functional properties of spinal visceral afferents supplying abdominal and pelvic organs, with special emphasis on visceral nociception
    • F. Cervero, Morrison J.F.B. Elsevier Science Publishers B.V. (Biomedical Division)
    • Janig W., Morrison J.F.B. Functional properties of spinal visceral afferents supplying abdominal and pelvic organs, with special emphasis on visceral nociception. Cervero F., Morrison J.F.B. Progress in Brain Research. 1986;87-114 Elsevier Science Publishers B.V. (Biomedical Division).
    • (1986) Progress in Brain Research , pp. 87-114
    • Janig, W.1    Morrison, J.F.B.2
  • 31
    • 0028334365 scopus 로고
    • NMDA and quisqualate modulation of visceral nociception in the rat
    • Kolhekar R., Gebhart G.F. NMDA and quisqualate modulation of visceral nociception in the rat. Brain Res. 651:1994;215-226.
    • (1994) Brain Res. , vol.651 , pp. 215-226
    • Kolhekar, R.1    Gebhart, G.F.2
  • 32
    • 0035847584 scopus 로고    scopus 로고
    • Long-term effects of short-lasting early local inflammatory insult
    • Lidow M.S., Song Z.M., Ren K. Long-term effects of short-lasting early local inflammatory insult. Neuroreport. 12:2001;399-403.
    • (2001) Neuroreport , vol.12 , pp. 399-403
    • Lidow, M.S.1    Song, Z.M.2    Ren, K.3
  • 33
    • 0346524987 scopus 로고    scopus 로고
    • Primary afferent sensitization in an animal model of chronic visceral pain
    • C. Lin, E.D. Al-Chaer, Primary afferent sensitization in an animal model of chronic visceral pain. J. Pain 3(2): Suppl. 1 (2002) 27 #706.
    • (2002) J. Pain , vol.3 , Issue.2 SUPPL. 1 , pp. 27
    • Lin, C.1    Al-Chaer, E.D.2
  • 34
    • 0032693009 scopus 로고    scopus 로고
    • Dorsal root reflexes and cutaneous neurogenic inflammation after intradermal injection of capsaicin in rats
    • Lin Q., Wu J., Willis W.D. Dorsal root reflexes and cutaneous neurogenic inflammation after intradermal injection of capsaicin in rats. J. Neurophysiol. 82:1999;2602-2611.
    • (1999) J. Neurophysiol. , vol.82 , pp. 2602-2611
    • Lin, Q.1    Wu, J.2    Willis, W.D.3
  • 35
    • 0346524986 scopus 로고    scopus 로고
    • Functional outcomes of neonatal colon pain measured in adult rats
    • H. Ma, Y. Park, E.D. Al-Chaer, Functional outcomes of neonatal colon pain measured in adult rats. J. Pain 3(2): Suppl. 1 (2002) p. 27, #707.
    • (2002) J. Pain , vol.3 , Issue.2 SUPPL. 1 , pp. 27
    • Ma, H.1    Park, Y.2    Al-Chaer, E.D.3
  • 38
    • 0023179019 scopus 로고
    • Characterization of neurons responses to noxious visceral and somatic stimuli in the medial lumbosacral spinal cord of the rat
    • Ness T.J., Gebhart G.F. Characterization of neurons responses to noxious visceral and somatic stimuli in the medial lumbosacral spinal cord of the rat. J. Neurophysiol. 57:1987;1867-1892.
    • (1987) J. Neurophysiol. , vol.57 , pp. 1867-1892
    • Ness, T.J.1    Gebhart, G.F.2
  • 39
    • 0023757461 scopus 로고
    • Characterization of neurons responses to noxious colorectal distension in the T13-L2 spinal cord of the rat
    • Ness T.J., Gebhart G.F. Characterization of neurons responses to noxious colorectal distension in the T13-L2 spinal cord of the rat. J. Neurophysiol. 60:1988;1419-1438.
    • (1988) J. Neurophysiol. , vol.60 , pp. 1419-1438
    • Ness, T.J.1    Gebhart, G.F.2
  • 40
    • 0023883691 scopus 로고
    • Coloretal distension as a noxious visceral stimulus: Physiologic and pharmacologic characterization of pseudaffective reflexes in the rat
    • Ness T.J., Gebhart G.F. Coloretal distension as a noxious visceral stimulus: physiologic and pharmacologic characterization of pseudaffective reflexes in the rat. Brain Res. 450:1988;153-169.
    • (1988) Brain Res. , vol.450 , pp. 153-169
    • Ness, T.J.1    Gebhart, G.F.2
  • 41
    • 0034725740 scopus 로고    scopus 로고
    • Altered nociceptive neuronal circuits after neonatal peripheral inflammation
    • Ruda M.A., Ling Q.D., Hohmann A.G., Peng Y.B., Tachibana T. Altered nociceptive neuronal circuits after neonatal peripheral inflammation. Science. 289:2000;628-631.
    • (2000) Science , vol.289 , pp. 628-631
    • Ruda, M.A.1    Ling, Q.D.2    Hohmann, A.G.3    Peng, Y.B.4    Tachibana, T.5
  • 42
    • 0028358969 scopus 로고
    • Characterization of mechanosensitive pelvic nerve afferent fibers innervating the colon of the rat
    • Sengupta J.N., Gebhart G.F. Characterization of mechanosensitive pelvic nerve afferent fibers innervating the colon of the rat. J. Neurophysiol. 71:1994;2046-2060.
    • (1994) J. Neurophysiol. , vol.71 , pp. 2046-2060
    • Sengupta, J.N.1    Gebhart, G.F.2
  • 43
    • 0000638069 scopus 로고
    • Gastrointestinal affrent fibers and sensation
    • L.R. Johnson. New York: Raven Press
    • Sengupta J.N., Gebhart G.F. Gastrointestinal affrent fibers and sensation. Johnson L.R. Physiology of the Gastrointestinal Tract. 1994;483-519 Raven Press, New York.
    • (1994) Physiology of the Gastrointestinal Tract , pp. 483-519
    • Sengupta, J.N.1    Gebhart, G.F.2
  • 44
    • 0002347374 scopus 로고
    • Mechanosensitive afferent fibers in the gastrointestinal and lower urinary tracts
    • G.F. Gebhart (Ed.), IASP Press, Seattle
    • J.N. Sengupta, G.F. Gebhart, Mechanosensitive afferent fibers in the gastrointestinal and lower urinary tracts, in: G.F. Gebhart (Ed.), Visceral pain, Progress in Pain Research and Management, IASP Press, Seattle, 1995, pp. 75-98.
    • (1995) Visceral pain, Progress in Pain Research and Management , pp. 75-98
    • Sengupta, J.N.1    Gebhart, G.F.2
  • 45
    • 0031046446 scopus 로고    scopus 로고
    • Effect of neonatal circumcision on pain response during subsequent routine vaccination
    • Taddio A., Katz J., Ilersich A.L., Koren G. Effect of neonatal circumcision on pain response during subsequent routine vaccination. Lancet. 349:1997;599-603.
    • (1997) Lancet , vol.349 , pp. 599-603
    • Taddio, A.1    Katz, J.2    Ilersich, A.L.3    Koren, G.4
  • 46
    • 0037151503 scopus 로고    scopus 로고
    • Conditioning and hyperalgesia in newborns exposed to repeated heel lances
    • Taddio A., Shah V., Gilbert-MacLeod C., Katz J. Conditioning and hyperalgesia in newborns exposed to repeated heel lances. J. Am. Med. Assoc. 288:2002;857-861.
    • (2002) J. Am. Med. Assoc. , vol.288 , pp. 857-861
    • Taddio, A.1    Shah, V.2    Gilbert-MacLeod, C.3    Katz, J.4
  • 47
    • 0028269894 scopus 로고
    • Dermatome mapping in the rat hindlimb by electrical stimulation of the spinal nerves
    • Takahashi Y., Nakajima Y., Sakamoto T. Dermatome mapping in the rat hindlimb by electrical stimulation of the spinal nerves. Neurosci. Lett. 168:(1-2):1994;85-88.
    • (1994) Neurosci. Lett. , vol.168 , Issue.1-2 , pp. 85-88
    • Takahashi, Y.1    Nakajima, Y.2    Sakamoto, T.3
  • 48
    • 0028925074 scopus 로고
    • Self-reported abuse and gastrointestinal disease in outpatients: Association with irritable bowel-type symptoms
    • Talley N.J., Fett S.L., Zinsmeister A.R. Self-reported abuse and gastrointestinal disease in outpatients: association with irritable bowel-type symptoms. Am. J. Gastroenterol. 90:1995;366-371.
    • (1995) Am. J. Gastroenterol. , vol.90 , pp. 366-371
    • Talley, N.J.1    Fett, S.L.2    Zinsmeister, A.R.3
  • 49
    • 0034124615 scopus 로고    scopus 로고
    • Irritable bowel syndrome in general practice: Prevalence, characteristics, and referral
    • Thompson W.G., Heaton K.W., Smyth G.T., Smyth C. Irritable bowel syndrome in general practice: prevalence, characteristics, and referral. Gut. 46:2000;78-82.
    • (2000) Gut , vol.46 , pp. 78-82
    • Thompson, W.G.1    Heaton, K.W.2    Smyth, G.T.3    Smyth, C.4
  • 51
    • 0034647828 scopus 로고    scopus 로고
    • Evidence for thoracolumbar spinal cord processing of inflammatory, but not acute colonic pain
    • Traub R.J. Evidence for thoracolumbar spinal cord processing of inflammatory, but not acute colonic pain. Neuroreport. 11:2000;2113-2116.
    • (2000) Neuroreport , vol.11 , pp. 2113-2116
    • Traub, R.J.1
  • 52
    • 0027424281 scopus 로고
    • Differential expression of c-fos and c-jun in two regions of the rat spinal cord following noxious colorectal distention
    • Traub R.J., Herdegen T., Gebhart G.F. Differential expression of c-fos and c-jun in two regions of the rat spinal cord following noxious colorectal distention. Neurosci. Lett. 160:1993;121-125.
    • (1993) Neurosci. Lett. , vol.160 , pp. 121-125
    • Traub, R.J.1    Herdegen, T.2    Gebhart, G.F.3
  • 53
    • 0032781742 scopus 로고    scopus 로고
    • The peptide content of colonic afferents decreases following colonic inflammation
    • Traub R.J., Hutchcroft K., Gebhart G.F. The peptide content of colonic afferents decreases following colonic inflammation. Peptides. 20:1999;267-273.
    • (1999) Peptides , vol.20 , pp. 267-273
    • Traub, R.J.1    Hutchcroft, K.2    Gebhart, G.F.3
  • 54
    • 0026728502 scopus 로고
    • Fos-like proteins in the umbosacral spinal cord following noxious and non-noxious colorectal distention in the rat
    • Traub R.J., Pechman P., Iadarola M.J., Gebhart G.F. Fos-like proteins in the umbosacral spinal cord following noxious and non-noxious colorectal distention in the rat. Pain. 49:1992;393-403.
    • (1992) Pain , vol.49 , pp. 393-403
    • Traub, R.J.1    Pechman, P.2    Iadarola, M.J.3    Gebhart, G.F.4
  • 55
    • 0034625770 scopus 로고    scopus 로고
    • Neuronal plasticity: Increasing the gain in pain
    • Woolf C.J., Salter M.W. Neuronal plasticity: increasing the gain in pain. Science. 288:2000;1765-1769.
    • (2000) Science , vol.288 , pp. 1765-1769
    • Woolf, C.J.1    Salter, M.W.2
  • 56
    • 0032833183 scopus 로고    scopus 로고
    • The NMDA receptor antagonist MK-801 attenuates c-Fos expression in the lumbosacral spinal cord following repetitive noxious and non-noxious colorectal distention
    • Zhai Q.Z., Traub R.J. The NMDA receptor antagonist MK-801 attenuates c-Fos expression in the lumbosacral spinal cord following repetitive noxious and non-noxious colorectal distention. Pain. 83:1999;321-329.
    • (1999) Pain , vol.83 , pp. 321-329
    • Zhai, Q.Z.1    Traub, R.J.2
  • 57
    • 0020525719 scopus 로고
    • Ethical guidelines for investigations of experimental pain in conscious animals
    • Zimmermann M. Ethical guidelines for investigations of experimental pain in conscious animals. Pain. 16:(2):1983;109-110.
    • (1983) Pain , vol.16 , Issue.2 , pp. 109-110
    • Zimmermann, M.1


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