Pharmacokinetics and antitumor properties in tumor-bearing mice of an enediol analogue inhibitor of glyoxalase I

Cancer Chemotherapy and Pharmacology

Volumn 46, Issue 2, 2000, Pages 156-166

  Sharkey, Ellyn M ^a   O'Neill, Hugh B ^a   Kavarana, Malcolm J ^a   Wang, Haibo ^a   Creighton, Donald J ^a   Sentz, Dorothy L ^b   Eiseman, Julie L ^b  

^a UNIVERSITY OF MARYLAND BALTIMORE COUNTY   (United States)

^b UNIVERSITY OF MARYLAND GREENEBAUM CANCER CENTER   (United States)

Author keywords

Glyoxalase I inhibitor; In vivo efficacy; Pharmacokinetics; S (N p chlorophenyl N hydroxycarbamoyl) glutathione

Indexed keywords

DOXORUBICIN; ENZYME INHIBITOR; GLUTATHIONE DERIVATIVE; N PARA CHLOROPHENYL N HYDROXYCARBAMOYL GLUTATHIONE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; COMPETITIVE INHIBITION; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; ENZYME INHIBITION; GROWTH INHIBITION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROLYSIS; MOUSE; NONHUMAN; OSMOTIC PUMP; PRIORITY JOURNAL; TUMOR GROWTH;

EID: 0033870067     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002800000130     Document Type: Article

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