The β-lactamase motif in Snm1 is required for repair of DNA double-strand breaks caused by interstrand crosslinks in S. cerevisiae

DNA Repair

Volumn 2, Issue 1, 2003, Pages 121-129

  Li, Xiaorong ^a   Moses, Robb E ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

Lacatamase; DNA repair; HO endonuclease; Interstrand crosslinks; S. cerevisiae; SNM1

Indexed keywords

BETA LACTAMASE; DOUBLE STRANDED DNA; PROTEIN; PROTEIN ARTEMIS; PROTEIN SNM1; UNCLASSIFIED DRUG; DNA BINDING PROTEIN; HYDROGEN PEROXIDE; NUCLEAR PROTEIN; PSO2 PROTEIN, S CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEIN;

ARTICLE; CONTROLLED STUDY; DNA CROSS LINKING; DNA REPAIR; DNA STRAND BREAKAGE; ELECTROPHORESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN MOTIF; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY; SITE DIRECTED MUTAGENESIS; DNA DAMAGE; GENETICS; METABOLISM; PHYSIOLOGY;

SACCHAROMYCES CEREVISIAE;

AMINO ACID MOTIFS; BETA-LACTAMASES; DNA DAMAGE; DNA REPAIR; DNA-BINDING PROTEINS; HYDROGEN PEROXIDE; NUCLEAR PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 0037413373     PISSN: 15687864     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1568-7864(02)00192-1     Document Type: Article

References (28)

1. Dronkert M.L., Kanaar R. Repair of DNA interstrand cross-links. Mutat. Res. 486:2001;217-247.
2. Magana-Schwencke N., Henriques J.A., Chanet R., Moustacchi E. The fate of 8-methoxypsoralen photoinduced crosslinks in nuclear and mitochondrial yeast DNA: comparison of wild-type and repair-deficient strains. Proc. Natl. Acad. Sci. U.S.A. 79:1982;1722-1726.
3. Dardalhon M., Averbeck D. Pulse-field gel electrophoresis analysis of the repair of psoralen plus UVA-induced DNA photoadducts in Saccharomyces cerevisiae. Mutat. Res. 336:1995;49-60.
4. Mchugh P.J., Sones W.R., Hartley J.A. Repair of intermediate structures produced at DNA interstrand cross-links in Saccharomyces cerevisiae. Mol. Cell. Biol. 20:2000;3425-3433.
5. Paques F., Haber J.E. Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae. Microbiol. Mol. Biol. Rev. 63:1999;349-404.
6. Strathern J.N., Klar A.J., Hicks J.B., Abraham J.A., Ivy J.M., Nasmyth K.A., McGill C. Homothallic switching of yeast mating-type cassettes is initiated by a double-stranded cut in the MAT locus. Cell. 31:1982;183-192.
7. Grossmann K.F., Ward A.M., Matkovic M.E., Folias A.E., Moses R.E. S. cerevisiae has three pathways for DNA interstrand crosslink repair. Mutat. Res. 487:2001;73-83.
8. Lawrence C.W., Hinkle D.C. DNA polymerase zeta and the control of DNA damage induced mutagenesis in eukaryotes. Cancer Surv. 28:1996;21-31.
9. Pastink A., Eeken J.C., Lohman P.H. Genomic integrity and the repair of double-strand DNA breaks. Mutat. Res. 480-481:2001;37-50.
10. Simon J.A., Szankasi P., Nguyen D.K., Ludlow C., Dunstan H.M., Roberts C.J., Jensen E.L., Hartwell L.H., Friend S.H. Differential toxicities of anticancer agents among DNA repair and checkpoint mutants of Saccharomyces cerevisiae. Cancer Res. 60:2000;328-333.
11. Grossmann K.F., Ward A.M., Moses R.E. Saccharomyces cerevisiae lacking snm1, rev3 or rad51 have a normal S phase but arrest permanently in G2 after cisplatin treatment. Mutat. Res. 461:2000;1-13.
12. Henriques J.A., Moustacchi E. Isolation and characterization of pso mutants sensitive to photo-addition of psoralen derivatives in Saccharomyces cerevisiae. Genetics. 95:1980;273-288.
13. Cassier-Chauvat C., Moustacchi E. Allelism between pso1-1 and rev3-1 mutants and between pso2-1 and snm1 mutants in Saccharomyces cerevisiae. Curr. Genet. 13:1988;37-40.
14. Henriques J.A., Brozmanova J., Brendel M. Role of PSO genes in the repair of photoinduced interstrand cross-links and photooxidative damage in the DNA of the yeast Saccharomyces cerevisiae. J. Photochem. Photobiol. B. 39:1997;185-196.
15. Dronkert M.L., DeWit J., Boeve M., Vasconcelos M.L., van Steeg H., Tan T.L., Hoeijmakers J.H., Kanaar R. Disruption of mouse SNM1 causes increased sensitivity to the DNA interstrand cross-linking agent mitomycin C. Mol. Cell Biol. 20:2000;4553-4561.
16. Richter D., Niegemann E., Brendel M. Molecular structure of the DNA cross-link repair gene SNM1 (PSO2) of the yeast Saccharomyces cerevisiae. Mol. Gen. Genet. 231:1992;194-200.
17. Niegemann E., Brendel M. A single amino acid change in SNM1-encoded protein leads to thermoconditional deficiency for DNA cross-link repair in Saccharomyces cerevisiae. Mutat. Res. 315:1994;275-279.
18. Wolter R., Siede W., Brendel M. Regulation of SNM1, an inducible Saccharomyces cerevisia gene required for repair of DNA cross-links. Mol. Gen. Genet. 250:1996;162-168.
19. Henriques J.A., Moustacchi B. Interactions between mutations for sensitivity to psoralen photoaddition (pso) and to radiation (rad) in Saccharomyces cerevisiae. J. Bacteriol. 148:1981;248-256.
20. Moshous D., Callebaut I., de Chasseval R., Corneo B., Cavazzana-Calvo M., Le Deist F., Tezcan I., Sanal O., Bertrand Y., Philippe N., Fischer A., de Villartay J.P. Artemis, a novel DNA Double-strand break repair/V(D)J recombination protein, is mutated in human severe combined immune deficiency. Cell. 105:2001;177-186.
21. Ma Y., Pannicke U., Schwarz K., Lieber R. Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination. Cell. 108:2002;781-794.
22. Hill J.E., Myers A.M., Koerner T.J., Tzagoloff A. Yeast/E. coli shuttle vectors with multiple unique restriction sites. Yeast. 2:1986;162-167.
23. J. Sambrook, D.W. Russell (Eds.), Southern hybridization, in: Molecular Cloning, A Laboratory Manual, 3rd Ed., Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, 2001, pp. 6.33-6.62.
24. Nickoloff J.A., Chen E.Y., Heffron F. A 24-base-pair DNA sequence from the MAT locus stimulates intergenic recombination in yeast. Proc. Natl. Acad. Sci. U.S.A. 83:1986;7831-7835.
25. Haber J.E. Partners and pathways repairing a double-strand break. Trends Genet. 16:2000;259-264.
26. Carfi A., Pares S., Duee E., Galleni M., Duez C., Frere J.M., Dideberg O. The 3-D structure of a zinc metallo-beta-lactamase from Bacillus cereus reveals a new type of protein fold. EMBO J. 14:1995;4914-4921.
27. Aravind L. An evolutionary classification of the metallo-beta-lactamase fold proteins. Silico Biol. 1(5):1999;69-91.
28. Signon L., Malkova A., Naylor M.L., Klein H., Haber J.E. Genetic requirements for RAD51- and RAD54-independent break-induced replication repair of a chromosomal double-strand break. Mol. Cell. Biol. 21:2001;2048-2056.