Members of the AP-1 family, c-Jun and c-Fos, functionally interact with JC virus early regulatory protein large T antigen

Journal of Virology

Volumn 77, Issue 9, 2003, Pages 5241-5252

  Kim, Joanne ^a   Woolridge, Stefanie ^a   Biffi, Renato ^a   Borghi, Elisa ^a,b   Lassak, Adam ^a   Ferrante, Pasquale ^b   Amini, Shohreh ^a   Khalili, Kamel ^a   Safak, Mahmut ^a,c  

^a Temple University   (United States)

^b IRCCS FONDAZIONE DON CARLO GNOCCHI   (Italy)

^c Laboratory of Molecular Neurovirology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN C FOS; PROTEIN C JUN; REGULATOR PROTEIN; TRANSCRIPTION FACTOR AP 1; VIRUS T ANTIGEN;

AFFINITY CHROMATOGRAPHY; ANTIGEN SPECIFICITY; ARTICLE; BINDING AFFINITY; BINDING SITE; BIOASSAY; CONTROLLED STUDY; DELETION MUTANT; DNA BINDING; GENE CONSTRUCT; GENE CONTROL; GENE MAPPING; GENETIC TRANSFECTION; GENOME; GLIA CELL; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; JC VIRUS; LABORATORY TEST; NONHUMAN; POLYOMA VIRUS; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN INTERACTION; TRANSCRIPTION REGULATION; VIRUS REPLICATION; VIRUS TRANSCRIPTION;

ANTIGENS, POLYOMAVIRUS TRANSFORMING; DNA, VIRAL; GENE DELETION; GENE EXPRESSION REGULATION, VIRAL; HUMANS; JC VIRUS; NEUROGLIA; PROTO-ONCOGENE PROTEINS C-FOS; PROTO-ONCOGENE PROTEINS C-JUN; TRANSCRIPTION FACTOR AP-1; TRANSCRIPTION, GENETIC; TUMOR CELLS, CULTURED; VIRUS REPLICATION;

EID: 0037405115     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.77.9.5241-5252.2003     Document Type: Article

References (63)

1. Amemiya, K., R. Traub, L. Durham, and E. O. Major. 1992. Adjacent nuclear factor-1 and activator protein binding sites in the enhancer of the neurotropic JC virus. A common characteristic of many brain-specific genes. J. Biol. Chem. 267:14204-14211.
2. Amemiya, K., R. Traub, L. Durham, and E. O. Major. 1989. Interaction of a nuclear factor-1-like protein with the regulatory region of the human polyomavirus JC virus. J. Biol. Chem. 264:7025-7032.
3. Angel, P., M. Imagawa, R. Chiu, B. Stein, R. J. Imbra, H. J. Rahmsdorf, C. Jonat, P. Herrlich, and M. Karin. 1987. Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor. Cell 49:729-739.
4. Angel, P., and M. Karin. 1991. The role of Jun, Fos and the AP-1 complex in cell proliferation and transformation. Biochim. Biophys. Acta 1072:129-157.
5. Angel, P., and M. Karin. 1992. Specific members of the Jun protein family regulate collagenase expression in response to various extracellular stimuli. Matrix Suppl. 1:156-164.
6. Berger, J. R., and M. Concha. 1995. Progressive multifocal leukoencephalopathy: the evolution of a disease once considered rare. J. Neurovirol. 1:5-18.
7. Bharucha, V. D., K. W. C. Peden, and G. I. Tennekoon. 1994. SV40 large T antigen with c-Jun down regulates myelin Po gene expression: a mechanism for papovaviral T antigen-mediated demyelination. Neuron 12:627-637.
8. Bossy-Wetzel, E., L. Bakiri, and M. Yaniv. 1997. Induction of apoptosis by the transcription factor c-Jun. EMBO J. 16:1695-1709.
9. Brenner, D. A., M. O'Hara, P. Angel, M. Chojkier, and M. Karin, 1989. Prolonged activation ofjun and collagenase genes by tumour necrosis factor-alpha. Nature 337:661-663.
10. Chang, C. F., G. L. Gallia, V. Muralidharan, N. N. Chen, P. Zoltick, E. Johnson, and K. Khalili. 1996. Evidence that replication of human neurotropic JC virus DNA in glial cells is regulated by the sequence-specific single-stranded DNA-binding protein Pur alpha. J. Virol. 70:4150-4156.
11. Chen, N. N., and K. Khalili. 1995. Transcriptional regulation of human JC polyomavirus promoters by cellular proteins YB-1 and Pur alpha in glial cells. J. Virol. 69:5843-5848.
12. Chen, S. L., Y. P. Tsoa, Y. L. Chen, S. J. Huang, J. L. Chang, and S. F. Wu. 1998. The induction of apoptosis by SV40 T antigen correlates with c-Jun overexpression. Virology 244:521-529.
13. Devary, Y., R. A. Gottlieb, L. F. Lau, and M. Karin. 1991. Rapid and preferential activation of the c-jun gene during the mammalian UV response. Mol. Cell. Biol. 11:2804-2811.
14. Frisque, R. J. 2001. Structure and function of JC virus T' proteins. J. Neurovirol. 7:293-297.
15. Frisque, R. J., and F. A. White. 1992. The molecular biology of JC virus, causative agent of progressive multifocal leukoencephalopathy. Humana Press Inc., Totowa, N.J.
16. Gallia, G. L., M. Safak, and K. Khalili. 1998, Interaction of the single-stranded DNA-binding protein Puralpha with the human polyomavirus JC virus early protein T-antigen, J. Biol. Chem. 273:32662-32669.
17. Glenn, G. M., and W. Echart. 1990. Transcriptional regulation of early-response genes during polyomavirus infection. J. Virol. 64:2193-2201.
18. Goldgaber, D., H. W. Harris, T. Hla, T. Maciag, R. J. Donnelly, J. S. Jacobsen, M. P. Vitek, and D. C. Gajdusek. 1989. Interleukin 1 regulates synthesis of amyloid beta-protein precursor mRNA in human endothelial cells. Proc. Natl. Acad. Sci. USA 86:7606-7610.
19. Graham, F. L., and A. J. van der Eb. 1973. A new technique for the assay of infectivity of human adenovirus 5 DNA. Virology 52:456-467.
20. Henson, J., J. Saffer, and H. Furneaux. 1992. The transcription factor Sp1 binds to the JC virus promoter and is selectively expressed in glial cells in human brain. Ann. Neurol. 32:72-77.
21. Herrlich, P., H. Ponta, and H. J. Rahmsdorf. 1992. DNA damage-induced gene expression: signal transduction and relation to growth factor signaling. Rev. Physiol. Biochem. Pharmacol. 119:187-223.
22. Hirt, B. J. 1976. Selective extraction of polyoma DNA from infected mouse cell culture. J. Mol. Biol. 26:365-369.
23. Johnson, R. S., B. van Lingen, V. E. Papaioannou, and B. M. Spiegelman. 1993. A null mutation at the c-jun locus causes embryonic lethality and retarded cell growth in culture. Genes Dev. 7:1309-1317.
24. Kerr, D., C. F. Chang, N. Chen, G. Gallia, G. Raj, B. Schwartz, and K. Khalili. 1994. Transcription of a human neurotropic virus promoter in glial cells: effect of YB-1 on expression of the JC virus late gene. J. Virol. 68:7637-7643.
25. Khalili, K., L. Feigenbaum, and G. Khoury. 1987. Evidence for a shift in 5′-termini of early viral RNA during the lytic cycle of JC virus. Virology 158:469-472.
26. Krynska, B., L. Del Valle, S. Croul, J. Gordon, C. D. Katsetos, M. Carbone, A. Giordano, and K. Khalili. 1999. Detection of human neurotropic JC virus DNA sequence and expression of the viral oncogenic protein in pediatric medulloblastomas. Proc. Natl. Acad. Sci. USA 96:11519-11524.
27. Krynska, B., J. Otte, R. Franks, K. Khalili, and S. Croul. 1999. Human ubiquitous JCV(CY) T-antigen gene induces brain tumors in experimental animals. Oncogene 18:39-46.
28. Laghi, L., A. E. Randolph, D. P. Chauhan, G. Marra, E. O. Major, J. V. Neel, and C. R. Boland. 1999. JC virus DNA is present in the mucosa of the human colon and in colorectal cancers. Proc. Natl. Acad. Sci. USA 96:7484-7489.
29. Lashgari, M. S., H. Tada, S. Amini, and K. Khalili. 1989. Regulation of JCVL promoter function: transactivation of JCVL promoter by JCV and SV40 early proteins. Virology 170:292-295.
30. Le-Niculescu, H., E. Bonfoco, Y. Kasuya, F. X. Claret, D. R. Green, and M. Karin. 1999. Withdrawal of survival factors results in activation of the INK pathway in neuronal cells leading to Fas ligand induction and cell death. Mol. Cell. Biol. 19:751-763.
31. Liu, C. K., A. P. Hope, and W. J. Atwood. 1998. The human polyomavirus, JCV, does not share receptor specificity with SV40 on human glial cells. J. Neurovirol. 4:49-58.
32. Lynch, K. J., and R. J. Frisque. 1991. Factors contributing to the restricted DNA replicating activity of JC virus. Virology 180:306-317.
33. Lynch, K. J., and R. J. Frisque. 1990. Identification of critical elements within the JC virus DNA replication origin, J. Virol. 64:5812-5822.
34. Lynch, K. J., S. Haggerty, and R. J. Frisque. 1994. DNA replication of chimeric JC virus-simian virus 40 genomes. Virology 204:819-822.
35. Monaco, M. C., B. F. Sabath, L. C. Durham, and E. O. Major. 2001. JC virus multiplication in human hematopoietic progenitor cells requires the NF-1 class D transcription factor. J. Virol. 75:9687-9695.
36. Pho, M. T., A. Ashok, and W. J. Atwood. 2000. JC virus enters human glial cells by clathrin-dependent receptor-mediated endocytosis. J. Virol. 74:2288-2292.
37. Raj, G. V., J. Gordon, T. J. Logan, D. J. Hall, A. Deluca, A. Giordano, and K. Khalili. 1995. Characterization of glioma cells derived from polyomavirus-induced brain tumors in hamsters. Int. J. Oncol. 7:801-808.
38. Raj, G. V., and K. Khalili. 1994. Identification and characterization of a novel GGA/C-binding protein, GBP-i, that is rapidly inducible by cytokines. Mol. Cell. Biol. 14:7770-7781.
39. Ranganathan, P. N., and K. Khalili. 1993. The transcriptional enhancer element, kappa B, regulates promoter activity of the human neurotropic virus, JCV, in cells derived from the CNS. Nucleic Acids Res. 21:1959-1964.
40. Rencic, A., J. Gordon, J. Otte, M. Curtis, A. Kovatich, P. Zoltick, K. Khalili, and D. Andrews. 1996. Detection of JC virus DNA sequence and expression of the viral oncoprotein, tumor antigen, in brain of immunocompetent patient with oligoastrocytoma. Proc. Natl. Acad. Sci. USA 93:7352-7357.
41. Renner, K., H. Leger, and M. Wegner. 1994. The POU domain protein Tst-1 and papovaviral large tumor antigen function synergistically to stimulate glia-specific gene expression of JC virus. Proc. Natl. Acad. Sci. USA 91:6433-6437.
42. Sadowska, B., R. Barucco, K. Khalili, and M. Safak. 2003. Regulation of human polyomavirus JC virus gene transcription by AP-1 in glial cells. J. Virol. 77:665-672.
43. Safak, M., R. Barrucco, A. Darbinyan, Y. Okada, K. Nagashima, and K. Khalili. 2001. Interaction of JC virus agno protein with T antigen modulates transcription and replication of the viral genome in glial cells. J. Virol. 75:1476-1486.
44. Safak, M., G. L. Gallia, S. A. Ansari, and K. Khalili. 1999. Physical and functional interaction between the Y-box binding protein YB-1 and human polyomavirus JC virus large T antigen. J. Virol. 73:10146-10157.
45. Safak, M. G., L. Gallia, and K. Khalili. 1999. A 23-bp sequence element from human neurotropic JC virus is responsive to NF-kappa B subunits. Virology 262:178-189.
46. Safak, M., G. L. Gallia, and K. Khalili. 1999. Reciprocal interaction between two cellular proteins, Puralpha and YB-1, modulates transcriptional activity of JCVCY in glial cells. Mol. Cell. Biol. 19:2712-2723.
47. Safak, M., and K. Khalili. 2001. Physical and functional interaction between viral and cellular proteins modulate JCV gene transcription. J. Neurovirol. 7:288-292.
48. Safak, M., B. Sadowska, R. Barrucco, and K. Khalili. 2002. Functional interaction between JC virus late regulatory agnoprotein and cellular Y-box binding transcription factor, YB-1. J. Virol. 76:3828-3838.
49. Schreiber, E., P. Matthias, M. M. Muller, and W. Schaffner. 1989. Rapid detection of octamer binding proteins with "mini-extracts", prepared from a small number of cells. Nucleic Acids Res. 17:6419.
50. Shaulian, E., and M. Karin. 2001. AP-1 in cell proliferation and survival. Oncogene 20:2390-2400.
51. Shaulian, E., M. Schreiber, F. Piu, M. Beeche, E. F. Wagner, and M. Karin. 2000. The mammalian UV response: c-Jun induction is required for exit from p53-imposed growth arrest. Cell 103:897-907.
52. Shaulian, E., and M. Karin, 2002. AP-1 as a regulator of cell life and death. Nat. Cell Biol. 4: E131-E136.
53. Small, J. A., G. Khoury, G. Jay, P. M. Howley, and G. A. Scangos. 1986. Early regions of JC virus and BK virus induce distinct and tissue-specific tumors in transgenic mice. Proc. Natl. Acad. Sci. USA 83:8288-8292.
54. Tavis, J. E., and R. J. Frisque. 1991. Altered DNA binding and replication activities of JC virus T-antigen mutants. Virology 183:239-250.
55. Trowbridge, P. W., and R. J. Frisque. 1990. Identification of three new JC virus proteins generated by alternative splicing of the early viral mRNA. J. Neurovirol. 1:195-206.
56. van Straaten, F., R. Muller, T. Curran, C. Van Beveren, and I. M. Verma. 1983. Complete nucleotide sequence of a human c-onc gene: deduced amino acid sequence of the human c-fos protein. Proc. Natl. Acad. Sci. USA 80:3183-3187.
57. Varakis, J., G. M. ZuRhein, B. L. Padgett, and D. L. Walker. 1978 Induction of peripheral neuroblastomas in Syrian hamsters after injection as neonates with JC virus, a human polyoma virus. Cancer Res. 38:1718-1722.
58. Vogt, P. 2001. Jun, the oncogene. Oncogene 20:2365-2377.
59. Walker, D. L., B. L. Padgett, G. M. ZuRhein, A. E. Albert, and R. F. Marsh. 1973. Human papovavirus (JC): induction of brain tumors in hamsters. Science 181:674-676.
60. Wegner, M., D. W. Drolet, and M. G. Rosenfeld. 1993. Regulation of JC virus by the POU-domain transcription factor Tst-1: implications for progressive multifocal leukoencephalopathy. Proc. Natl. Acad. Sci. USA 90:4743-4747.
61. Wei, G., C. K. Liu, and W. J. Atwood. 2000. JC virus binds to primary human glial cells, tonsillar stromal cells, and B-lymphocytes, but not to T lymphocytes. J. Neurovirol. 6:127-136.
62. Wisdom, R. 1992. AP-1: one switch for many signals. Exp. Cell Res. 253:180-185.
63. Zullo, J., C. D. Stiles, and R. L. Garcea. 1987. Regulation of c-myc and c-fos mRNA levels by polyomavirus: distinct roles for the capsid protein VP1 and the viral early proteins. Proc. Natl. Acad. Sci. USA 84:1210-1214.