Structural requirements of flavonoids for nitric oxide production inhibitory activity and mechanism of action

Bioorganic and Medicinal Chemistry

Volumn 11, Issue 9, 2003, Pages 1995-2000

  Matsuda, Hisashi ^a   Morikawa, Toshio ^a   Ando, Shin ^a   Toguchida, Iwao ^a   Yoshikawa, Masayuki ^a  

^a KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

APIGENIN; DIOSMETIN; FLAVANOID; FLAVONOL DERIVATIVE; GLYCOSIDE; HEXA O METHYLMYRICETIN; HYDROXYL GROUP; ISOFLAVONE DERIVATIVE; LUTEOLIN; MYRICETIN; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR; TETRA O METHYLLUTEOLIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG CYTOTOXICITY; DRUG MECHANISM; DRUG POTENTIATION; DRUG STRUCTURE; ENZYME INHIBITION; METHYLATION; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; STRUCTURE ACTIVITY RELATION;

EID: 0037401853     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(03)00067-1     Document Type: Article

References (28)

1. Salerno L., Sorrenti V., Di Giacomo C., Romeo G., Siracusa M.A. Curr. Pharm. Des. 8:2000;177.
2. Titheradge M.A. Biochem. Biophys. Acta. 1411:1999;437.
3. (a) Nussler A.K., Billiar T.R. J. Leukoc. Biol. 54:1993;171.
4. (b) Natarajan K., Singh S., Burke T.R. Jr., Grunberger D., Aggarwal B.B. Proc. Natl. Acad. Sci. U.S.A. 93:1996;9090.
5. Yoshikawa M., Murakami T., Shimada H., Yoshizumi S., Saka M., Yamahara J., Matsuda H. Chem. Pharm. Bull. 46:1998;1008.
6. Matsuda H., Murakami T., Kageura T., Ninomiya K., Toguchida I., Nishida N., Yoshikawa M. Bioorg. Med. Chem. Lett. 8:1998;2191.
7. Yoshikawa M., Morikawa T., Toguchida I., Harima S., Matsuda H. Chem. Pharm. Bull. 48:2000;651.
8. (a) Muraoka O., Fujimoto M., Tanabe G., Kubo M., Minematsu T., Matsuda H., Morikawa T., Toguchida I., Yoshikawa M. Bioorg. Med. Chem. Lett. 11:2001;2217.
9. (b) Morikawa T., Matsuda H., Toguchida I., Ueda K., Yoshikawa M. J. Nat. Prod. 65:2002;1468.
10. (a) Matsuda H., Morikawa T., Sakamoto Y., Toguchida I., Yoshikawa M. Heterocycles. 56:2002;45.
11. (b) Matsuda H., Morikawa M., Sakamoto Y., Toguchida I., Yoshikawa M. Bioorg. Med. Chem. 10:2002;2527.
12. (a) Matsuda H., Kageura T., Morikawa T., Toguchida I., Harima S., Yoshikawa M. Bioorg. Med. Chem. Lett. 10:2000;323.
13. (b) Kageura T., Matsuda H., Morikawa T., Toguchida I., Harima S., Oda M., Yoshikawa M. Bioorg. Med. Chem. 9:2001;1887.
14. Matsuda H., Kageura T., Oda M., Morikawa T., Sakamoto Y., Yoshikawa M. Chem. Pharm. Bull. 49:2001;716.
15. Matsuda H., Kageura T., Toguchida I., Ueda H., Morikawa T., Yoshikawa M. Life Sci. 66:2000;2151.
16. (a) Matsuda H., Ninomiya K., Morikawa T., Yoshikawa M. Bioorg. Med. Chem. Lett. 8:1998;339.
17. (b) Matsuda H., Morikawa T., Toguchida I., Ninomiya K., Yoshikawa M. Heterocycles. 55:2001;841.
18. (c) Matsuda H., Morikawa T., Toguchida I., Ninomiya K., Yoshikawa M. Chem. Pharm. Bull. 49:2001;1558.
19. Matsuda H., Kageura T., Toguchida I., Murakami T., Kishi A., Yoshikawa M. Bioorg. Med. Chem. Lett. 9:1999;3081.
20. Matsuda H., Toguchida I., Ninomiya K., Kageura T., Morikawa T., Yoshikawa M. Bioorg. Med. Chem. 11:2003;709.
21. Tao J., Morikawa T., Toguchida I., Ando S., Matsuda H., Yoshikawa M. Bioorg. Med. Chem. 10:2002;4005.
22. Matsuda H., Ishikado A., Nishida N., Ninomiya K., Fujiwara H., Kobayashi Y., Yoshikawa M. Bioorg. Med. Chem. Lett. 8:1998;2939.
23. Morikawa, T., Tao, J., Toguchida, I., Matsuda, H., Yoshikawa, M. J. Nat. Prod. 2003, 66, 86.
24. Shimoda H., Nishida N., Ninomiya K., Matsuda H., Yoshikawa M. Heterocycles. 55:2001;2043.
25. Matsuda H., Morikawa T., Toguchida I., Yoshikawa M. Chem. Pharm. Bull. 50:2002;788.
26. Matsuda H., Morikawa T., Ueda K., Managi H., Yoshikawa M. Bioorg. Med. Chem. 10:2002;3123.
27. Kim H.K., Cheon B.S., Kim Y.H., Kim S.Y., Kim H.P. Biochem. Pharmacol. 58:1999;759.
28. Raso G.M., Meli R., Di Carlo G., Pacilio M., Di Carlo R. Life Sci. 68:2001;921.