Structural requirements of flavonoids and related compounds for aldose reductase inhibitory activity

Chemical and Pharmaceutical Bulletin

Volumn 50, Issue 6, 2002, Pages 788-795

  Matsuda, Hisashi ^a   Morikawa, Toshio ^a   Toguchida, Iwao ^a   Yoshikawa, Masayuki ^a  

^a KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Aldose reductase inhibitor; Desmanthin 1; Flavonoid; Guaijaverin; Quercitrin; Structural requirement

Indexed keywords

3 HYDROXYFLAVONE; 3',4' DIHYDROXYFLAVONE; 3',4',7 TRIHYDROXYFLAVONE; 4',7 DIHYDROXYFLAVONE; 7 HYDROXYFLAVONE; ACACETIN 7 O (6'' ALPHA RHAMNOPYRANOSYL) BETA GLUCOPYRANOSIDE; ALDEHYDE REDUCTASE; ALDOSE REDUCTASE INHIBITOR; APIGENIN; APIGENIN 7 O BETA GLUCOPYRANOSIDE; CHRYSIN; DESMANTHIN 1; DIOSMETIN; DIOSMETIN 7 O BETA GLUCOPYRANOSIDE; EPALRESTAT; FLAVONE; FLAVONE DERIVATIVE; FLAVONOID; FLAVONOL DERIVATIVE; GUAIJAVERIN; IZALPININ; KAEMPFEROL; KAEMPFEROL 3 O BETA GLUCOPYRANOSIDURONIC ACID; LUTEOLIN; LUTEOLIN 7 O BETA GLUCOPYRANOSIDE; LUTEOLIN 7 O BETA GLUCOPYRANOSIDURONIC ACID; PILLOIN; QUERCITRIN; TECTOCHRYSIN; UNCLASSIFIED DRUG; UNINDEXED DRUG; DRUG DERIVATIVE; ENZYME INHIBITOR; METHANOL; PLANT EXTRACT; QUERCETIN;

ARTICLE; CHEMICAL BOND; CHEMICAL COMPOSITION; COMMERCIAL PHENOMENA; DRUG ACTIVITY; DRUG DETERMINATION; DRUG ISOLATION; DRUG POTENCY; DRUG STRUCTURE; ENZYME INHIBITION; EXAMINATION; FOOD; LENS; ANIMAL; CHEMISTRY; DRUG ANTAGONISM; ENZYMOLOGY; METABOLISM; RAT; STRUCTURE ACTIVITY RELATION;

ALDEHYDE REDUCTASE; ANIMALS; ENZYME INHIBITORS; FLAVONOIDS; LENS, CRYSTALLINE; METHANOL; PLANT EXTRACTS; QUERCETIN; RATS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0036594601     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.50.788     Document Type: Article

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