Drosophila Tufted is a gain-of-function allele of the proneural gene amos

Genetics

Volumn 163, Issue 4, 2003, Pages 1413-1425

  Lai, Eric C ^a  

^a University of California Berkeley   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLELE; AMOS GENE; ARTICLE; DROSOPHILA MELANOGASTER; GENE; GENE EXPRESSION; GENE MUTATION; INSECT GENETICS; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; TUFTED GENE;

ANIMALS; DROSOPHILA; DROSOPHILA PROTEINS; GENES, DOMINANT; MICROSCOPY, ELECTRON, SCANNING; NERVE GROWTH FACTORS; NERVOUS SYSTEM MALFORMATIONS;

ARACHNIDA; DROSOPHILA MELANOGASTER; HEXAPODA; INSECTA; MELANOGASTER;

EID: 0037397784     PISSN: 00166731     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (73)

1. ALONSO, M. C., and C. V. CABRERA, 1988 The achaete-scute gene complex of Drosophila melanogaster comprises four homologous genes. EMBO J. 7: 2585-2591.
2. APIDIANAKIS, Y., A. C. NAGEL, A. CHALKIADAKI, A. PREISS and C. DELIDAKIS, 1999 Overexpression of the m4 and mα genes of the E(spl)-Complex antagonizes Notch mediated lateral inhibition. Mech. Dev. 86: 39-50.
3. ARNHEIM, N., 1967 The regional effects of two mutants in Drosophila analyzed by means of mosaics. Genetics 56: 253-263.
4. ARTAVANIS-TSAKONAS, S., M. D. RAND and R. J. LAKE, 1999 Notch signaling: cell fate control and signal integration in development. Science 284: 770-776.
5. BAILEY, A. M., and J. W. POSAKONY, 1995 Suppressor of Hairless directly activates transcription of Enhancer of split Complex genes in response to Notch receptor activity. Genes Dev. 9: 2609-2622.
6. BALCELLS, L., J. MODOLELL and M. RUIZ-GOMEZ, 1988 A unitary basis for different Hairy-wing mutations of Drosophila melanogaster. EMBO J. 7: 3899-3906.
7. BELLEN, H. J., C. J. O'KANE, C. WILSON, U. GROSSNIKLAUS, R. K. PEARSON et al., 1989 P-element-mediated enhancer detection: a versatile method to study development in Drosophila. Genes Dev. 3: 1288-1300.
8. BERTRAND, N., D. CASTRO and F. GUILLEMOT, 2002 Proneural genes and the specification of neural cell types. Nat. Rev. Neurosci. 3: 517-530.
9. BRAND, A. H., and N. PERRIMON, 1993 Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118: 401-415.
10. BRAND, M., A. P. JARMAN, L. Y. JAN and Y. N. JAN, 1993 asense is a Drosophila neural precursor gene and is capable of initiating sense organ formation. Development 119: 1-17.
11. BRIDGES, C., and T. H. MORGAN, 1923 The Third-Chromosome Group of Mutant Characters of Drosophila melanogaster. Pub. 327, Carnegic Institute, Washington, DC.
12. BRUNNER, E., D. BRUNNER, W. Fu, E. HAFEN and K. BASLER, 1999 The dominant mutation Glazed is a gain-of-function allele of wingless that, similar to loss of APC, interferes with normal eye development. Dev. Biol. 206: 178-188.
13. CAMPUZANO, S., L. CARRAMOLINO, C. V. CABRERA, M. RUIZ-GOMEZ, R. VILLARES et al., 1985 Molecular genetics of the acaete-scute gene complex of D. melanogaster. Cell 40: 327-338.
14. CAMPUZANO, S., L. BALCELLS, R. VILLARES, L. CARRAMOLINO, L. GARCIA-ALONSO et al., 1986 Excess function Hairy-wing mutations caused by gypsy and copia insertions within structural genes of the achaete-scute locus of Drosophila. Cell 44: 303-312.
15. CAPDEVILA, J., and I. GUERRERO, 1994 Targeted expression of the signaling molecule decapentaplegic induces pattern duplications and growth alterations in Drosophila wings. EMBO J. 13: 4459-4468.
16. CARMENA, A., M. BATE and F. JIMÉNEZ, 1995 Lethal of scute, a proneural gene, participates in the specification of muscle progenitors during Drosophila embryogenesis. Genes Dev. 9: 2373-2383.
17. CAUDY, M., H. VÄSSIN, M. BRAND, R. TUMA, L. Y. JAN et al., 1988 daughterless, a Drosophila gene essential for both neurogenesis and sex determination, has sequence similarities to myc and the achaete-scute complex. Cell 55: 1061-1067.
18. CHANUT, F., K. WOO, S. PEREIRA, T. DONOHOE, S.-Y. CHANG et al., 2002 Rough eye is a gain-of-function allele of amos that disrupts regulation of the proneural gene atonal during Drosophila retinal differentiation. Genetics 160: 623-635.
19. CHIEN, C. T., C. D. HSIAO, L. Y. JAN and Y. N. JAN, 1996 Neuronal type information encoded in the basic-helix-loop-helix domain of proneural genes. Proc. Natl. Acad. Sci. USA 93: 13239-13244.
20. CULI, J., and J. MODOLELL, 1998 Proneural gene self-stimulation in neural precursors: an essential mechanism for sense organ development that is regulated by Notch signaling. Genes Dev. 12: 2036-2047.
21. CULI, J., E. MARTIN-BLANCO and J. MODOLELL, 2001 The EGF receptor and N signaling pathways act antagonistically in Drosophila mesothorax bristle patterning. Development 128: 299-308.
22. DE CELIS, J. F., and S. BRAY, 1997 Feed-back mechanisms affecting Notch activation at the dorsoventral boundary in the Drosophila wing. Development 124: 3241-3251.
23. DOMINGUEZ, M., and S. CAMPUZANO, 1993 asense, a member of the Drosophila achaete-scute complex, is a proneural and neural differentiation gene. EMBO J. 12: 2049-2060.
24. FICHELSON, P., and M. GHO, 2003 The glial cell undergoes apoptosis in the microchaete lineage of Drosophila. Development 130: 123-133.
25. FLYBASE, 1998 FlyBase: a Drosophila database. Nucleic Acids Res. 26: 85-88.
26. FRANKFORT, B., R. NOLO, Z. ZHANG, H. BELLEN and G. MARDON, 2001 senseless repression of rough is required for R8 photoreceptor differentiation in the developing Drosophila eye. Neuron 32: 403-414.
27. FUSE, N., H. MATAKATSU, M. TANIGUCHI and S. HAYASHI, 1999 Snailtype zinc finger proteins prevent neurogenesis in Scutoid and transgenic animals of Drosophila. Dev. Genes Evol. 209: 573-580.
28. GARCÍA-BELLIDO, A., 1979 Genetic analysis of the achaete-scute system of Drosophila melanogaster, Genetics 91: 491-520.
29. GARCÍA-BELLIDO, A., and P. SANTAMARIA, 1978 Developmental analysis of the achaete-scute system of Drosophila melanogaster. Genetics 88: 469-486.
30. GHO, M., Y. BELLAÏCHE and F. SCHWEISGUTH, 1999 Revisiting the Drosophila microchaete lineage: a novel intrinsically asymmetric cell division generates a glial cell. Development 126: 3573-3584.
31. GHYSEN, A., and J. RICHELLE, 1979 Determination of sensory bristles and pattern formation in Drosophila. Dev. Biol. 70: 438-452.
32. GOMEZ-SKARMETA, J. L., I. RODRIGUEZ, C. MARTINEZ, J. CULI, D. FERRES-MARCO et al., 1995 Cis-regulation of achaete and scute: shared enhancer-like elements drive their coexpression in proneural clusters of the imaginal discs. Genes Dev. 9: 1869-1882.
33. GOULDING, S., P. ZUR LAGE and A. P. JARMAN, 2000 amos, a proneural gene for Drosophila olfactoy sense organs that is regulated by lozenge. Neuron 25: 69-78.
34. GUPTA, B. P., and V. RODRIGUES, 1997 atonal is a proneural gene for a subset of olfactory sense organs in Drosophila. Genes Cells 2: 225-233.
35. HINZ, U., B. GIEBEL and J. A. CAMPOS-ORTEGA, 1994 The basichelix-loop-helix domain of Drosophila lethal of scute protein is sufficient for proneural function and activates neurogenic genes. Cell 76: 77-87.
36. HUANG, M.-H., C.-H. Hsu and C.-T. CHIEN, 2000 The pronenral gene amos promotes multiple dendritic neuron formation in the Drosophila peripheral nervous system. Neuron 25: 57-67.
37. IVES, P., 1952 New mutants report. Dros. Inf. Serv. 26: 65.
38. JARMAN, A. P., and I. AHMED, 1998 The specificity of proneural genes in determining Drosophila sense organ identity. Mech. Dev. 76: 117-125.
39. JARMAN, A., E. GKELL, L. ACKERMAN, L. JAN and Y. JAN, 1994 atonal is the proneural gene for Drosophila photoreceptors. Nature 369: 398-400.
40. JARMAN, A. P., Y. GRAU, L. Y. JAN and Y. N. JAN, 1993 atonal is a proneural gene that directs chordotonal organ formation in the Drosophila peripheral nervous system. Cell 73: 1307-1321.
41. JIMENEZ, G., and D. ISH-HOROWICZ, 1997 A chimeric Enhancer-ofsplit transcriptional activator drives neural development and achaete-scute expression. Mol. Cell. Biol. 17: 4355-4362.
42. LAI, E. C., and G. M. RUBIN, 2001 neuralized functions cell-autonomously to regulate a subset of Notch-dependent processes during adult Drosophila development. Dev. Biol. 231: 217-233.
43. LAI, E. C., R. BODNER, J. KAVALER, G. FRESCHI and J. W. POSAKONY, 2000a Antagonism of Notch signaling activity by members of a novel protein family encoded by the Bearded and Enhancer of split gene complexes. Development 127: 291-306.
44. LAI, E. C., R. BODNER and J. W. POSAKONY, 2000b The Enhancer of split Complex of Drosophila includes four Notch-regulated members of the Bearded gene family. Development 127: 3441-3455.
45. LAI, E. C., G. DEBLANDRE, C. KINTNER and G. M. RUBIN, 2001 Drosophila neuralized is a ubiquitin ligase that promotes the internalization and degradation of Delta. Dev. Cell 1: 783-794.
46. LEVITEN, M. W., and J. W. POSAKONY, 1996 Gain-of-function alleles of Bearded interfere with alternative cell fate decisions in Drosophila adult sensory organ development. Dev. Biol. 176: 264-283.
47. LEVITEN, M. W., E. C. LAI and J. W. POSAKONY, 1997 The Drosophila gene Bearded encodes a novel small protein and shares 3′ UTR sequence motifs with multiple Enhancer of split complex genes. Development 124: 4039-4051.
48. LINDSLEY, D. L., and G. G. ZIMM, 1992 The Genome of Drosophila melanogaster. Academic Press, San Diego.
49. MARTIN-BERMUDO, M. D., C. MARTINEZ, A. RODRIGUEZ and F. JIMENEZ, 1991 Distribution and function of the lethal of scute gene product during early neurogenesis in Drosophila. Development 113: 445-454.
50. MARTINEZ, C., and J. MODOLELL, 1991 Cross-regulatory interactions between the proneural achaete and scute genes of Drosophila. Science 251: 1485-1487.
51. MILÁN, M., F. J. DIAZ-BENJUMEA and S. M. COHEN, 1998 Beadex encodes an LMO protein that regulates Apterous LIM-homeodomain activity in Drosophila wing development: a model for LMO oncogene function. Genes Dev. 12: 2912-2920.
52. MOSCOSO DEL PRADO, J. and A. GARCÍA-BELLIDO, 1984 Genetic regulation of the Achaete-scute complex of Drosophila melanogaster. Roux's Arch. Dev. Biol. 193: 242-245.
53. MOZER, B., 2001 Dominant Drop mutants are gain-of-function alleles of the muscle segment homeobox gene (msh) whose overexpression leads to the arrest of eye development. Dev. Biol. 233: 380-393.
54. MUNGALL, C., S. MISRA, B. BERMAN, J. CARLSON, E. FRISE et al., 2003 An integrated computational pipeline and database to support whole-genome sequence annotation. Genome Biol. 3: 0081.1-10.
55. NOLO, R., L. ABBOTT and H. J. BELLEN, 2000 Senseless, a Zn finger transcription factor, is necessary and sufficient for sensory organ development in Drosophila. Cell 102: 349-362.
56. NOLO, R., L. ABBOTT and H. J. BELLEN, 2001 Drosophila Lyra mutations are gain-of-function mutations of senseless. Genetics 157: 307-315.
57. OHSAKO, S., J. HYER, G. PANGANIBAN, I. OLIVER and M. CAUDY, 1994 Hairy function as a DNA-binding helix-loop-helix repressor of Drosophila sensory organ formation. Genes Dev. 8: 2743-2755.
58. PICKUP, A., M. LAMKA, Q. SUN, M. YIP and H. LIPSHITZ, 2002 Control of photoreceptor cell morphology, planar polarity and epithelial integrity during Drosophila eye development. Development 129: 2247-2258.
59. REDDY, G., and V. RODRIGUES, 1999 A glial cell arises from an additional division within the mechanosensory lineage during development of the microchate on the Drosophila notum. Development 126: 4617-4622.
60. RITTERHOFF, R., 1952 Report of new mutants (Tufted). Dros. Inf. Serv. 26: 68-69.
61. RØRTH, P., 1996 A modular misexpression screen in Drosophila detecting tissue-specific phenotypes. Proc. Natl. Acad. Sci. USA 93: 12418-12422.
62. SHORESH, M., S. ORGAD, O. SHMUELI, R. WERCZBERGER, D. GELBAUM et al., 1998 Overexpression Beadex mutations and loss-of-function heldup-a mutations in Drosophila affect the 3′ regulatory and coding components, respectively, of the Dlmo gene. Genetics 150: 283-299.
63. SINGSON, A., M. W. LEVITEN, A. G. BANG, X. H. HUA and J. W. POSAKONY, 1994 Direct downstream targets of proneural activators in the imaginal disc include genes involved in lateral inhibitory signaling. Genes Dev. 8: 2058-2071.
64. SKEATH, J. B., and S. B. CARROLL, 1991 Regulation of achaete-scute gene expression and sensors, organ pattern formation in the Drosophila wing. Genes Dev. 5: 984-995.
65. STAEHLING-HAMPTON, K., P. JACKSON, M. CLARK, A. H. BRAND and F. M. HOFFMAN, 1994 Specificity of bone morphogenetic protein-related factors: cell fate and gene expression changes in Drosophila embryos induced by decapentaplegic but not 60A. Cell Growth Diff. 5: 585-593.
66. SUN, Y., L. Y. JAN and Y. N. JAN, 1998 Transcriptional regulation of atonal during development of the Drosophila peripheral nervous system. Development 125: 3731-3740.
67. SUN, Y., L. Y. JAN and Y. N. JAN, 2000 Ectopic scute induces Drosophila ommatidia development without R8 founder photoreceptors. Proc. Natl. Acad. Sci. USA 97: 6815-6819.
68. VAN DOREN, M., P. A. POWELL, D. PASTERNAK, A. SINGSON and J. W. POSAKONY, 1992 Spatial regulation of proneural gene activity: auto- and cross-activation of achaete is antagonized by extramacrochaetae. Genes Dev. 6: 2592-2605.
69. VAN DOREN, M., A. BAILEY, J. ESNAYRA, K. EDE and J. POSAKONY, 1994 Negative regulation of proneural gene activity: hairy is a direct transcriptional repressor of achaete. Genes Dev. 8: 2729-2742.
70. VILLA-CUESTA, E., J. DE NAVASCUÉS, M. RUIZ-GÓMEZ, R. DIEZ DEL CORRAL,M. DOMÍNGUEZ et al., 2003 Tufted is a gain-of-function allele that promotes ectopic expression of the proneural gene amos in Drosophila. Genetics 163: 1403-1412.
71. WRIGHT, T. R., R. HODGETTS and A. SHERALD, 1976 The genetics of dopa decarboxylase in Drosophila melanogaster. Genetics 84: 267-285.
72. ZENG, C., N. J. JUSTICE, S. ABDELILAH, Y.-M. CHAN, L. Y. JAN et al., 1998 The Drosophila LIM-only gene, dLMO, is muated in Beadex alleles and might represent an evolutionarily conserved function in appendage development. Proc. Natl. Acad. Sci. USA 95: 10637-10642.
73. ZUR LAGE, P., and A. P. JARMAN, 1999 Antagonism of EGFR and Notch signaling in the reiterative recruitment of Drosophila adult chordotonal sense organ precursors. Development 126: 31493157.