A new paradigm for drug discovery: Integrating clinical, genetic, genomic and molecular phenotype data to identify drug targets

Biochemical Society Transactions

Volumn 31, Issue 2, 2003, Pages 437-443

  Schadt, E E ^a   Monks, S A ^a,b   Friend, S H ^a,c  

^a ROSETTA INPHARMATICS   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Clinical; Genetic linkage; MRNA expression; QTL (quantitative trait loci); Sub phenotype

Indexed keywords

CONFERENCE PAPER; DRUG TARGETING; GENETIC LINKAGE; GENOMICS; GENOTYPE; MESSENGER RNA SYNTHESIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEOMICS; QUANTITATIVE TRAIT LOCUS; SINGLE NUCLEOTIDE POLYMORPHISM; TARGET CELL;

ANIMALS; DRUG DESIGN; GENE EXPRESSION REGULATION; GENOMICS; HUMANS; LINKAGE (GENETICS); SYNTENY;

EID: 0037396404     PISSN: 03005127     EISSN: None     Source Type: Journal    
DOI: 10.1042/BST0310437     Document Type: Conference Paper

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