Single dexamethasone injection increases alveolar fluid clearance in adult rats

Critical Care Medicine

Volumn 31, Issue 4, 2003, Pages 1183-1189

  Noda, Masafumi ^a   Suzuki, Satoshi ^a   Tsubochi, Hiroyoshi ^a   Sugita, Makoto ^a   Maeda, Sumiko ^a   Kobayashi, Seiichi ^b   Kubo, Hiroshi ^b   Kondo, Takashi ^a  

^a TOHOKU UNIVERSITY   (Japan)

^b TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Alveolar fluid clearance; Dexamethasone; Epithelial Na+ channels; Na+ K+ adenosine triphosphatase; Pulmonary edema; Spironolactone

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); AMILORIDE; DEXAMETHASONE; MESSENGER RNA; OUABAIN; SODIUM CHANNEL; SODIUM ION; SPIRONOLACTONE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; ENZYME ACTIVITY; HYDROLYSIS; HYPOXEMIA; INJECTION; ION TRANSPORT; LUNG ALVEOLUS EPITHELIUM; LUNG DIFFUSION; LUNG EDEMA; LUNG FLUID; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STEROID THERAPY;

ANIMALS; DEXAMETHASONE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; EPITHELIUM; EXTRAVASCULAR LUNG WATER; GLUCOCORTICOIDS; INJECTIONS, INTRAPERITONEAL; MALE; NA(+)-K(+)-EXCHANGING ATPASE; OUABAIN; PULMONARY ALVEOLI; PULMONARY EDEMA; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SODIUM CHANNELS;

EID: 0037390747     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.CCM.0000059640.77535.29     Document Type: Article

References (52)

1. Sakuma T, Okaniwa G, Nakada T, et al: Alveolar fluid clearance in the resected human lungs. Am J Respir Crit Care Med 1994; 150:305-310
2. Matthay MA, Folkesson HG, Verkman AS: Salt and water transport across alveolar and distal airway epithelia in adult lung. Am J Physiol Lung Cell Mol Physiol 1996; 270:L487-L503
3. Borok Z, Liebler JM, Lubman RL, et al: Na transport proteins are expressed by rat alveolar epithelial type I cells. Am J Physiol Lung Cell Mol Physiol 2002; 282:L599-L608
4. O'Brodovich H: Epithelial ion transport in the fetal and perinatal lung. Am J Physiol Cell Physiol 1991; 261:C555-C564
5. Matthay MA, Wiener-Kronish JP: Intact epithelial barrier function is critical for the resolution of alveolar edema in humans. Am Rev Respir Dis 1990; 142:1250-1257
6. Ware LB, Matthay MA: Alveolar fluid clearance is impaired in the majority of patients with acute lung injury and the acute respiratory distress syndrome. Am J Respir Crit Care Med 2001; 163:1376-1383
7. Berthiaume Y, Staub NC, Matthay MA: Beta-adrenergic agonists increase lung liquid clearance in anesthetized sheep. J Clin Invest 1987; 79:335-343
8. Cott GR, Sugahara K, Mason RJ: Stimulation of net active ion transport across alveolar cell monolayers. Am J Physiol Cell Physiol 1986; 250:C222-C227
9. Effros RM, Mason GR, Sietsema K, et al: Fluid reabsorption and glucose consumption in edematous rat lungs. Circ Res 1987; 60:708-719
10. Goodman BE, Brown SES, Crandall ED: Regulation of transport across pulmonary alveolar epithelial cell monolayers. J Appl Physiol 1984; 57:703-710
11. Sakuma T, Folkesson HG, Suzuki S, et al: Beta-adrenergic agonist stimulated alveolar fluid clearance in ex vivo human and rat lungs. Am J Respir Crit Care Med 1997; 155:506-512
12. Morgan EE, Nodnichak CM, Stader SM, et al: Prolonged isoproterenol infusion impairs the ability of β2-agonists to increase alveolar liquid clearance. Am J Physiol Lung Cell Mol Physiol 2002; 282:L666-L674
13. + channel by steroid hormones. EMBO J 1994; 13:2177-2181
14. Omar SA, De Cristofaro JD, Agarwal BI, et al: Effects of prenatal steroids on water and sodium homeostasis in extremely low birth weight neonates. Pediatrics 1999; 104:482-488
15. + channel subunits are differentially regulated during development and by steroids. Am J Physiol Cell Physiol 1995; 269:C805-C812
16. Venkatesh VC, Katzberg HD: Glucocorticoid regulation of epithelial sodium channel genes in human fetal lung. Am J Physiol Lung Cell Mol Physiol 1997; 273:L227-L233
17. Liggins GC: Premature delivery of fetal lambs infused with glucocorticoids. J Endocrinol 1969; 45:515-523
18. Bernard GR, Luce JM, Sprung CL, et al: High-dose corticosteroids in patients with the adult respiratory distress syndrome. N Engl J Med 1987; 317:1565-1570
19. Bone RC, Fisher CJ Jr, Clemmer TP, et al: Early methylprednisolone treatment for septic syndrome and the adult respiratory distress syndrome. Chest 1988; 92:1032-1036
20. Meduri GU, Headley AS, Golden E, et al: Effect of prolonged methylprednisolone therapy in unresolving acute respiratory distress syndrome: A randomized controlled trial. JAMA 1998; 280:159-165
21. Barquin N, Ciccolella DE, Ridge KE, et al: Dexamethasone upregulates the Na-K-ATPase in rat alveolar epithelial cells. Am J Physiol Lung Cell Mol Physiol 1997; 273:L825-L830
22. +-ATPase by cAMP and dexamethasone in alveolar epithelial cells. Am J Physiol Lung Cell Mol Physiol 2001; 281:L217-L230
23. Folkesson HG, Norlin A, Wang Y, et al: Dexamethasone and thyroid hormone pretreatment upregulate alveolar epithelial fluid clearance in adult rats. J Appl Physiol 2000; 88:416-424
24. Arriza JL, Weinberger C, Cerelli G, et al: Cloning of human mineralocorticoid receptor complementary DNA: Structural and functional kinship with the glucocorticoid receptor. Science 1987; 237:268-275
25. Suzuki S, Tsubochi H, Suzuki T, et al: Modulation of transalveolar fluid absorption by endogenous aldosterone in adult rats. Exp Lung Res 2001; 27:143-155
26. + channels in alveolar epithelial cells. Am J Physiol Lung Cell Mol Physiol 1996; 271:L1-L22
27. Kleyman TR, Gragoe EJ Jr: Amiloride and its analogs as tools in the study of ion transport. J Membr Biol 1988; 105:1-21
28. +-ATPase in rat type II pneumocytes. J Appl Physiol 1986; 60:1584-1589
29. Russo RM, Lubman RL, Crandall ED: Evidence for amiloride-sensitive sodium channels in alveolar epithelial cells. Am J Physiol 1992; 262:L405-L411
30. Suzuki S, Noda M, Sugita M, et al: Difference in the effect of phloridzin on alveolar fluid absorption in anesthetized rats and in ex vivo rat lungs. Exp Lung Res 1999; 25:393-406
31. Otulakowski G, Rafii B, Bremner HR, et al: Structure and hormone responsiveness of the gene encoding the α-subunit of the rat amiloride-sensitive sodium channel. Am J Respir Cell Mol Biol 1999; 20:1028-1040
32. Bremner HR, Freywald T, O'Brodovich HM, et al: Promoter analysis of the gene encoding the β-subunit of the rat amiloride-sensitive epithelial sodium channel. Am J Physiol Lung Cell Mol Physiol 2002; 282:L124-L134
33. Kreutz R, Struk B, Rubattu S, et al: Role of the α-, β-, and γ-subunit of epithelial sodium channel in a model of polygenic hypertension. Hypertension 1997; 29:131-136
34. +-ATPase α-subunit from rat brain. Biochemistry 1986; 25:8125-8132
35. +-ATPase β-subunit protein. J Biol Chem 1987; 262:4905-4910
36. Butcher PA, Steele LW, Ward MR, et al: Transport of sodium into apical membrane vesicles prepared from fetal sheep alveolar type II cells. Biochim Biophys Acta 1989; 950:50-55
37. Dobbs LG, Gonzalez R, Williams MC: An improved method for isolating type II cells in high yield and purity. Am Rev Respir Dis 1986; 134:141-145
38. Edelson JD, Shannon JM, Mason RJ: Alkaline phosphatase: A marker of alveolar type II cell differentiation. Am Rev Respir Dis 1988; 138:1268-1275
39. Bradford MM: A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976; 72:248-254
40. +-ATPase activity by β-adrenergic agonist in alveolar type II cells. Am J Physiol Lung Cell Mol Physiol 1995; 268:L983-L990
41. Canessa CM, Horisberger JD, Rossier BC: Functional cloning of the epithelial sodium channel: Relation with genes involved in neurodegeneration. Nature 1994; 361:467-470
42. + channel is made of three homologous subunits. Nature 1994; 367:463-467
43. Sayegh R, Auerbach SD, Li X, et al: Glucocorticoid induction of epithelial sodium channel expression in lung and renal epithelia occurs via trans-activation of a hormone response element in the 5′-flanking region of the human epithelial sodium channel α subunit gene. J Biol Chem 1999; 274:12431-12437
44. + transport is associated with regulated ENaC and sgkl expression. Am J Physiol Lung Cell Mol Physiol 2002; 282:L631-L641
45. + channel in colon, lung and kidney. Pflugers Arch 1995; 430:299-307
46. + channels by dexamethasone. Am J Physiol Cell Physiol 2000; 279:C762-C770
47. Vejlstrup NG, Boyd CAR, Dorrington KL: Effect of lung inflation on active and passive liquid clearance from in vivo rabbit lung. Am J Physiol Lung Cell Mol Physiol 1994; 267:L482-L487
48. Nici L, Dowin R, Gilmore-Hebert M, et al: Upregulation of rat lung Na-K-ATPase during hyperoxic injury. Am J Physiol Lung Cell Physiol 1991; 261:L307-L314
49. Orlowski J, Lingrel JB: Tissue-specific and developmental regulation of rat Na,K-ATPase catalytic α isoform and β subunit mRNAs. J Biol Chem 1988; 263:10436-10442
50. Pressley TA: Ion concentration-dependent regulation of Na,K-pump abundance. J Membr Biol 1988; 105:187-195
51. + transport. J Physiol 1989; 410:425-441
52. Mick VE, Itani OA, Loftus RW, et al: The α-subunit of the epithelial sodium channel is an aldosterone-induced transcript in mammalian collecting ducts, and this transcriptional response is mediated via distinct cis-elements in the 5′-flanking region of the gene. Mol Endocrinol 2001; 15:575-588