Transfection of oocytes and other types of ovarian cells in rabbits after direct injection into uterine arteries of adenoviruses and plasmid/liposomes

Gene Therapy

Volumn 10, Issue 7, 2003, Pages 580-584

  Laurema, A ^a   Heikkila A ^a   Keski Nisula, L ^a   Heikura, T ^a   Lehtolainen, P ^a   Manninen, H ^a   Tuomisto, T T ^a   Heinonen, S ^a   Yla Herttuala S ^a,b  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b KUOPIO UNIVERSITY HOSPITAL   (Finland)

Author keywords

Adenovirus; Gene therapy; LacZ; Ovary; Plasmid liposome; Thymidine kinase

Indexed keywords

BETA GALACTOSIDASE; GANCICLOVIR; LIPOSOME; PLASMID VECTOR; THYMIDINE KINASE; VIRUS VECTOR;

ADENOVIRUS; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL DESTRUCTION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CORPUS LUTEUM; DEVELOPMENTAL STAGE; FEMALE; GENE THERAPY; GENE TRANSFER; GENETIC SUSCEPTIBILITY; GENETIC TRANSFECTION; GRANULOSA CELL; IN VITRO STUDY; LASER; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; OOCYTE; OVARY CELL; OVARY FOLLICLE; PLASMID; POLYMERASE CHAIN REACTION; PREGNANCY; PRIORITY JOURNAL; RABBIT; UTERINE ARTERY; VIRAL GENE DELIVERY SYSTEM; ZONA PELLUCIDA;

ADENOVIRIDAE; ANIMALS; ARTERIES; BETA-GALACTOSIDASE; FEMALE; GENE THERAPY; GENETIC VECTORS; INJECTIONS, INTRA-ARTERIAL; LIPOSOMES; OOCYTES; OVARY; RABBITS; SIMPLEXVIRUS; THYMIDINE KINASE; TRANSDUCTION, GENETIC; TRANSFECTION; UTERUS;

ADENOVIRIDAE; ANIMALIA; DNA VIRUSES; HERPES; ORYCTOLAGUS CUNICULUS; SIMPLEXVIRUS;

EID: 0037385455     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3301918     Document Type: Article

References (20)

1. Gordon JW. Direct exposure of mouse ovaries and oocytes to high doses of an adenovirus gene therapy vector fails to lead to germ cell transduction. Mol Ther 2001; 3: 557-564.
2. Hall SJ, Bar-Chama N, Ta S, Gordon JW. Direct exposure of mouse spermatogenic cells to high doses of adenovirus gene therapy vector does not result in germ cell transduction. Hum Gene Ther 2000; 11: 1705-1712.
3. Paielli DL et al. Evaluation of the biodistribution, persistence, toxicity, and potential of germ-line transmission of a replication-competent human adenovirus following intraprostatic administration in the mouse. Mol Ther 2000; 1: 263-274.
4. Hiltunen MO et al. Biodistribution of adenoviral vector to nontarget tissues after local in vivo gene transfer to arterial wall using intravascular and periadventitial gene delivery methods. FASEB J 2000; 14: 2230-2236.
5. Ye X et al. Evaluating the potential of germ line transmission after intravenous administration of recombinant adenovirus in the C3 H mouse. Hum Gene Ther 1998; 9: 2135-2142.
6. McLachlan G et al. Evaluation in vitro and in vivo of cationic liposome-expression construct complexes for cystic fibrosis gene therapy. Gene Ther 1995; 2: 614-622.
7. Zhu N, Liggitt D, Liu Y, Debs R. Systemic gene expression after intravenous DNA delivery into adult mice. Science 1993; 261: 209-211.
8. Chan AW et al. Transgenic monkeys produced by retroviral gene transfer into mature oocytes. Science 2001; 291: 309-312.
9. Tsukui T, Kanegae Y, Saito I, Toyoda Y. Transgenesis by adenovirus-mediated gene transfer into mouse zona-free eggs. Nat Biotechnol 1996; 14: 982-985.
10. Heikkila A et al. Angiographically guided utero-placental gene transfer in rabbits with adenoviruses, plasmid/liposomes and plasmid/polyethyleneimine complexes. Gene Ther 2001; 8: 784-788.
11. Moolten FL. Drug sensitivity ("suicide") genes for selective cancer chemotherapy. Cancer Gene Ther 1994; 1: 279-287.
12. Sandmair AM et al. Thymidine kinase gene therapy for human malignant glioma, using replication-deficient retroviruses or adenoviruses. Hum Gene Ther 2000; 11: 2197-2105.
13. Aghi M, Hochberg F, Breakefield XO. Prodrug activation enzymes in cancer gene therapy. J Gene Med 2000; 2: 148-164.
14. Kazazian HHJ. An estimated frequency of endogenous insertional mutations in humans. Nat Genet 1999; 22: 130.
15. Peng KW et al. Organ distribution of gene expression after intravenous infusion of targeted and untargeted lentiviral vectors. Gene Ther 2001; 8: 1456-1463.
16. Lee VH, Dunbar BS. Developmental expression of the rabbit 55-kDa zona pellucida protein and messenger RNA in ovarian follicles. Dev Biol 1993; 155: 371-382.
17. Laitinen M et al. Adenovirus-mediated gene transfer to lower limb artery of patients with chronic critical leg ischemia. Hum Gene Ther 1998; 9: 1481-1486.
18. Ylä-Herttuala S et al. Colocalization of 15-lipoxygenase mRNA and protein with epitopes of oxidized low density lipoprotein in macrophage-rich areas of atherosclerotic lesions. Proc Natl Acad Sci USA 1990; 87: 6959-6963.
19. Ylä-Herttuala S et al. Transfer of 15-lipoxygenase gene into rabbit iliac arteries results in the appearance of oxidation-specific lipid-protein adducts characteristic of oxidized low density lipoprotein. J Clin Invest 1995; 95: 2692-2698.
20. Patel AC et al. Hypermethylation of the p16(Ink4a) promoter in B6C3F1 mouse primary lung adenocarcinomas and mouse lung cell lines. Carcinogenesis 2000; 21: 1691-1700.