-
1
-
-
0025329333
-
Chemosensitization of the Nitrosoureas by 2-Nitroinidazoles in the subcutaneous 9L tumor model: Pharmacokinetic and structural-activity considerations. I
-
Wong KH, Wallen CA, Wheeler KT. 1999. Chemosensitization of the Nitrosoureas by 2-Nitroinidazoles in the subcutaneous 9L tumor model: Pharmacokinetic and structural-activity considerations. I. J Radiat Oncol 18:1043-1050.
-
(1999)
J Radiat Oncol
, vol.18
, pp. 1043-1050
-
-
Wong, K.H.1
Wallen, C.A.2
Wheeler, K.T.3
-
2
-
-
0027380417
-
Phase I pharmacokinetic/biochemical study of the nitroimidazoles hypoxic cell sensitizer SR2508 (etanidazole) in combination with cyclophosphamide
-
O'Dwyer PJ, LaCreta FP, Walczak J, Cox T, Litwin S, Hoffman JP, Zimny M, Comis RL. 1993. Phase I pharmacokinetic/biochemical study of the nitroimidazoles hypoxic cell sensitizer SR2508 (etanidazole) in combination with cyclophosphamide. Br J Cancer 68:756-766.
-
(1993)
Br J Cancer
, vol.68
, pp. 756-766
-
-
O'Dwyer, P.J.1
LaCreta, F.P.2
Walczak, J.3
Cox, T.4
Litwin, S.5
Hoffman, J.P.6
Zimny, M.7
Comis, R.L.8
-
3
-
-
0033212142
-
Novel radiation sensitizers targeting tissue hypoxia
-
Rowinsky EK. 1999. Novel radiation sensitizers targeting tissue hypoxia. Oncology 13(10;Suppl 5):61-70.
-
(1999)
Oncology
, vol.13
, Issue.10 SUPPL. 5
, pp. 61-70
-
-
Rowinsky, E.K.1
-
4
-
-
85031202728
-
-
1983. Nitroimidazoles of low toxicity and high activity as radiosensitizers of hypoxic tumor cells. U.S. Pat. 4371540
-
Lee WW, Brwon JM, Martinez AP, Cory MJ. 1983. Nitroimidazoles of low toxicity and high activity as radiosensitizers of hypoxic tumor cells. U.S. Pat. 4371540.
-
-
-
Lee, W.W.1
Brwon, J.M.2
Martinez, A.P.3
Cory, M.J.4
-
5
-
-
0027264545
-
Molecular dimension and properties of N-[1-(2-Hydroxyethyl)-2-nitro-1H-immidazole-1-yl]acetamide (SR2508)
-
Dabrow MB, Katz H, O'Dwyer PJ, Afshar C, Glusker JP. 1993. Molecular dimension and properties of N-[1-(2-Hydroxyethyl)-2-nitro-1H-immidazole-1-yl]acetamide (SR2508). Arch Biochem Biophys 302(1):259-264.
-
(1993)
Arch Biochem Biophys
, vol.302
, Issue.1
, pp. 259-264
-
-
Dabrow, M.B.1
Katz, H.2
O'Dwyer, P.J.3
Afshar, C.4
Glusker, J.P.5
-
6
-
-
0028229850
-
A phase I study of etanidazole and radiotherapy in malignant glioma
-
Reise NE, Loeffler JS, Wen P, Alexander E, Black PM, Coleman CN. 1994. A phase I study of etanidazole and radiotherapy in malignant glioma. Int J Radiat Oncol Biol Phys 29(3):617-620.
-
(1994)
Int J Radiat Oncol Biol Phys
, vol.29
, Issue.3
, pp. 617-620
-
-
Reise, N.E.1
Loeffler, J.S.2
Wen, P.3
Alexander, E.4
Black, P.M.5
Coleman, C.N.6
-
7
-
-
0028333614
-
Low concentration of nitroimidazoles: Effective radiosensitizers at low doses
-
Skov KA, Macphail S. 1994. Low concentration of nitroimidazoles: Effective radiosensitizers at low doses. Int J Radiat Oncol Biol Phys 29(1):87-93.
-
(1994)
Int J Radiat Oncol Biol Phys
, vol.29
, Issue.1
, pp. 87-93
-
-
Skov, K.A.1
Macphail, S.2
-
8
-
-
0021157611
-
Initial report of the phase I trial of the hypoxic cell radiosensitizer SR-2508
-
Coleman CN, Urtasun RC, Wasserman TH, Hancock S, Harris JW, Halsey J, Hirst K. 1984. Initial report of the phase I trial of the hypoxic cell radiosensitizer SR-2508. Int J Radiat Oncol Biol Phys 10(9):749-753.
-
(1984)
Int J Radiat Oncol Biol Phys
, vol.10
, Issue.9
, pp. 749-753
-
-
Coleman, C.N.1
Urtasun, R.C.2
Wasserman, T.H.3
Hancock, S.4
Harris, J.W.5
Halsey, J.6
Hirst, K.7
-
9
-
-
0024584819
-
Transport of fluid and macromolecules in tumors. I. Role of interstitial pressure and convection
-
Baxter LT, Jain RK. 1989. Transport of fluid and macromolecules in tumors. I. Role of interstitial pressure and convection. Microvasc Res 37:77-104.
-
(1989)
Microvasc Res
, vol.37
, pp. 77-104
-
-
Baxter, L.T.1
Jain, R.K.2
-
10
-
-
0001672512
-
Blood brain barrier
-
Dulbecco FR, editor. San Diego: Academic Press
-
Robinson PJ, Rapoport SI. Blood brain barrier. In: Dulbecco FR, editor. Encyclopedia of human biology, vol. 1. San Diego: Academic Press, pp 716-727.
-
Encyclopedia of Human Biology
, vol.1
, pp. 716-727
-
-
Robinson, P.J.1
Rapoport, S.I.2
-
11
-
-
0028917333
-
Placebo controlled trial of safety and efficacy of intraoperative controlled delivery by biodegradable polymers of chemotherapy for recurrent gliomas
-
Brem H, Piantadosi S, Burger PC, Walker M, Selker R, Vick NA, Black K, Sisti M, Brem S, Mohor G, Muller P, Morawetz R, Schold SC. 1995. Placebo controlled trial of safety and efficacy of intraoperative controlled delivery by biodegradable polymers of chemotherapy for recurrent gliomas. Lancet 345:1008-1012.
-
(1995)
Lancet
, vol.345
, pp. 1008-1012
-
-
Brem, H.1
Piantadosi, S.2
Burger, P.C.3
Walker, M.4
Selker, R.5
Vick, N.A.6
Black, K.7
Sisti, M.8
Brem, S.9
Mohor, G.10
Muller, P.11
Morawetz, R.12
Schold, S.C.13
-
12
-
-
0002951467
-
Polymer-based drug delivery to the brain
-
Brem H, Langer R. 1996. Polymer-based drug delivery to the brain. Sci Med 3(4):2-11.
-
(1996)
Sci Med
, vol.3
, Issue.4
, pp. 2-11
-
-
Brem, H.1
Langer, R.2
-
13
-
-
0032845609
-
Selected advances in drug delivery and tissue engineering
-
Langer R. 1999. Selected advances in drug delivery and tissue engineering. J Control Release 62:7-11.
-
(1999)
J Control Release
, vol.62
, pp. 7-11
-
-
Langer, R.1
-
14
-
-
0032706567
-
Radiosensitization of a mouse tumor model by sustained intra-tumoral release of Etanidazole and Tirapazamine using a biodegradable polymer implant device
-
Donald T, Yapp T, Lloyd DK, Zhu J, Lehnert S. 1999. Radiosensitization of a mouse tumor model by sustained intra-tumoral release of Etanidazole and Tirapazamine using a biodegradable polymer implant device. Radiother Oncol 53:77-84.
-
(1999)
Radiother Oncol
, vol.53
, pp. 77-84
-
-
Donald, T.1
Yapp, T.2
Lloyd, D.K.3
Zhu, J.4
Lehnert, S.5
-
15
-
-
0032538650
-
Three dimensional simulation of IgG delivery to tumors
-
Wang CH, Li J. 1998. Three dimensional simulation of IgG delivery to tumors. Chem Eng Sci 53(20):3579-3600.
-
(1998)
Chem Eng Sci
, vol.53
, Issue.20
, pp. 3579-3600
-
-
Wang, C.H.1
Li, J.2
-
17
-
-
0028828136
-
A mathematical model of polymeric controlled drug release and transport in the brain
-
Reisfeld B, Kalyanasundram S, Leong KW. 1995. A mathematical model of polymeric controlled drug release and transport in the brain. J Control Release 36:199-207.
-
(1995)
J Control Release
, vol.36
, pp. 199-207
-
-
Reisfeld, B.1
Kalyanasundram, S.2
Leong, K.W.3
-
18
-
-
0017542025
-
Dynamics of drug transport in solid tumors: Distributed parameter model
-
Jain RK, Wei J. 1977. Dynamics of drug transport in solid tumors: Distributed parameter model. J Bioeng 1:313-330.
-
(1977)
J Bioeng
, vol.1
, pp. 313-330
-
-
Jain, R.K.1
Wei, J.2
-
19
-
-
0028849284
-
Time-dependent behaviour of interstitial fluid pressure in solid tumors: Implication for drug delivery
-
Netti PA, Baxter LT, Boucher Y, Skalak YR, Jain RK. 1995. Time-dependent behaviour of interstitial fluid pressure in solid tumors: Implication for drug delivery. Cancer Res 55:5451-5458.
-
(1995)
Cancer Res
, vol.55
, pp. 5451-5458
-
-
Netti, P.A.1
Baxter, L.T.2
Boucher, Y.3
Skalak, Y.R.4
Jain, R.K.5
-
20
-
-
0030658067
-
A finite element model for predicting the distribution of drugs delivered intracranially to the brain
-
Kalyansundaram S, Calhoun VD, Leong KW. 1997. A finite element model for predicting the distribution of drugs delivered intracranially to the brain. Am J Physiol 45(5):R1810-R1821.
-
(1997)
Am J Physiol
, vol.45
, Issue.5
-
-
Kalyansundaram, S.1
Calhoun, V.D.2
Leong, K.W.3
-
21
-
-
0029884848
-
Chemotherapeutic drugs released from polymers: Distribution of 1,3-bi(2-chloroethyl)-1-nitrosurea in the rat brain
-
Fung LK, Shin M, Tyler B, Brem H, Saltzman WM. 1996. Chemotherapeutic drugs released from polymers: Distribution of 1,3-bi(2-chloroethyl)-1-nitrosurea in the rat brain. Pharm Res 13(5):671-682.
-
(1996)
Pharm Res
, vol.13
, Issue.5
, pp. 671-682
-
-
Fung, L.K.1
Shin, M.2
Tyler, B.3
Brem, H.4
Saltzman, W.M.5
-
22
-
-
0003495105
-
-
New York: Pergamon Press
-
Goodman GA, Rall TW, Nies AS, Taylor P. 1990. Goodman and Gilman's the pharmacological basis of therapeutics, 8th ed. New York: Pergamon Press, p 1221.
-
(1990)
Goodman and Gilman's the Pharmacological Basis of Therapeutics, 8th Ed.
, pp. 1221
-
-
Goodman, G.A.1
Rall, T.W.2
Nies, A.S.3
Taylor, P.4
-
23
-
-
0027389182
-
Interstitial chemotherapy of the 9L gliosarcoma: Controlled release polymers for drug delivery in the brain
-
Tarmargo RJ, Myseros S, Epstein JI, Yang MB, Chasin M, Brem H. 1993. Interstitial chemotherapy of the 9L gliosarcoma: Controlled release polymers for drug delivery in the brain. Cancer Res 53:329-333.
-
(1993)
Cancer Res
, vol.53
, pp. 329-333
-
-
Tarmargo, R.J.1
Myseros, S.2
Epstein, J.I.3
Yang, M.B.4
Chasin, M.5
Brem, H.6
-
24
-
-
84958443129
-
Steady state free thermal convection of liquid in a saturated permeable medium
-
Wooding RA. 1957. Steady state free thermal convection of liquid in a saturated permeable medium. J Fluid Mech 2:273-285.
-
(1957)
J Fluid Mech
, vol.2
, pp. 273-285
-
-
Wooding, R.A.1
-
25
-
-
0036017234
-
PEG modulated release of etanidazole from implantable PLGA/PLLA discs
-
Wang FJ, Lee TKY, Wang CH. 2002. PEG modulated release of etanidazole from implantable PLGA/PLLA discs. Biomaterials 23:3555-3566.
-
(2002)
Biomaterials
, vol.23
, pp. 3555-3566
-
-
Wang, F.J.1
Lee, T.K.Y.2
Wang, C.H.3
-
26
-
-
0025067997
-
A mathematical model for vasogenic brain edema
-
Long D, et al., editors. New York: Raven Press
-
Nagashima T, Horwitz B, Rapoport SI. 1990. A mathematical model for vasogenic brain edema. In: Long D, et al., editors. Advances in neurology, vol 52. New York: Raven Press, pp 317-325.
-
(1990)
Advances in Neurology
, vol.52
, pp. 317-325
-
-
Nagashima, T.1
Horwitz, B.2
Rapoport, S.I.3
-
28
-
-
0025616418
-
The finite element analysis of brain oedema associated with intracranial meningiomas
-
Nagashima T, Tada Y, Hamano S, Skakakura M, Masaoka K, Tamaki N, Matsumoto S. 1990. The finite element analysis of brain oedema associated with intracranial meningiomas. Acta Neurochir Suppl 51:155-157.
-
(1990)
Acta Neurochir Suppl
, vol.51
, pp. 155-157
-
-
Nagashima, T.1
Tada, Y.2
Hamano, S.3
Skakakura, M.4
Masaoka, K.5
Tamaki, N.6
Matsumoto, S.7
-
30
-
-
0023125107
-
Relationship between the neurotoxicity of the hypoxic cell radiosensitizer SR 2508 and the pharmacokinetic profile
-
Coleman NC, Halsey J, Cox RS, Hirst VK, Blaschke TE, Howes AE, Wasserman TH, Urtasun RC, Pajak T, Hancock S, Phillips TL, Noll L. 1987. Relationship between the neurotoxicity of the hypoxic cell radiosensitizer SR 2508 and the pharmacokinetic profile. Cancer Res 47:319-322.
-
(1987)
Cancer Res
, vol.47
, pp. 319-322
-
-
Coleman, N.C.1
Halsey, J.2
Cox, R.S.3
Hirst, V.K.4
Blaschke, T.E.5
Howes, A.E.6
Wasserman, T.H.7
Urtasun, R.C.8
Pajak, T.9
Hancock, S.10
Phillips, T.L.11
Noll, L.12
-
32
-
-
0012697103
-
Solvent evaporation, solvent extraction and spray drying for polylactide microspheres preparation
-
Bologna
-
Conti B, Pavanetto F, Genta I, Giunchedi P. 1991. Solvent evaporation, solvent extraction and spray drying for polylactide microspheres preparation. Proceedings of 10th pharmaceutical technology conference, Bologna, pp 16-18.
-
(1991)
Proceedings of 10th Pharmaceutical Technology Conference
, pp. 16-18
-
-
Conti, B.1
Pavanetto, F.2
Genta, I.3
Giunchedi, P.4
-
33
-
-
0027373002
-
Evaluation of spray drying as a method for polylactide and polylactide-co-glycolide microspheres preparation
-
Pavanetto F, Genta I, Giunchedi P, Conti B. 1993. Evaluation of spray drying as a method for polylactide and polylactide-co-glycolide microspheres preparation. J Microencapsulat 10(4):487-497.
-
(1993)
J Microencapsulat
, vol.10
, Issue.4
, pp. 487-497
-
-
Pavanetto, F.1
Genta, I.2
Giunchedi, P.3
Conti, B.4
-
34
-
-
0029555077
-
Distribution of 1,3-bis(2-Chloroethyl)-1-Nitrosourea and tracers in the rabbit brain after interstitial delivery by biodegradable polymer implants
-
Strasser JF, Fung LK, Eller S, Grossman SA, Saltzman WM. 1995. Distribution of 1,3-bis(2-Chloroethyl)-1-Nitrosourea and tracers in the rabbit brain after interstitial delivery by biodegradable polymer implants. J Pharmacol Exp Ther 275(3):1647-1655.
-
(1995)
J Pharmacol Exp Ther
, vol.275
, Issue.3
, pp. 1647-1655
-
-
Strasser, J.F.1
Fung, L.K.2
Eller, S.3
Grossman, S.A.4
Saltzman, W.M.5
|