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Volumn 97, Issue 7, 2003, Pages 1630-1638

Molecular markers of outcome after radiotherapy in patients with prostate carcinoma: Ki-67, bcl-2, bax, and bcl-x

Author keywords

Bax; Bcl 2; Bcl x; MIB 1; Prostate carcinoma; Prostate specific antigen; Radiotherapy

Indexed keywords

KI 67 ANTIGEN; PROSTATE SPECIFIC ANTIGEN; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL X;

EID: 0037378596     PISSN: 0008543X     EISSN: None     Source Type: Journal    
DOI: 10.1002/cncr.11230     Document Type: Article
Times cited : (95)

References (55)
  • 1
    • 0026655474 scopus 로고
    • Bcl-2 initiates a new category of oncogenes: Regulators of cell death
    • Korsmeyer SJ. Bcl-2 initiates a new category of oncogenes: regulators of cell death. Blood. 1992;80:879-886.
    • (1992) Blood , vol.80 , pp. 879-886
    • Korsmeyer, S.J.1
  • 2
    • 0029077281 scopus 로고
    • Overexpression of bcl-2 protects prostate cancer cells from apoptosis in vitro and confers resistance to androgen depletion in vivo
    • Raffo AJ, Perlman H, Chen M-W, et al. Overexpression of bcl-2 protects prostate cancer cells from apoptosis in vitro and confers resistance to androgen depletion in vivo. Cancer Res. 1995;55:4438-4445.
    • (1995) Cancer Res , vol.55 , pp. 4438-4445
    • Raffo, A.J.1    Perlman, H.2    Chen, M.-W.3
  • 3
    • 0029826151 scopus 로고    scopus 로고
    • Bcl-2 immunoreactivity in prostate tumorigenesis in relation to prostatic intraepithelial neoplasia, grade, hormonal status, metastatic growth and survival
    • Stattin P, Damber J-E, Karlberg L, Nordgren H, Bergh A. Bcl-2 immunoreactivity in prostate tumorigenesis in relation to prostatic intraepithelial neoplasia, grade, hormonal status, metastatic growth and survival. Urol Res. 1996;24: 257-264.
    • (1996) Urol Res , vol.24 , pp. 257-264
    • Stattin, P.1    Damber, J.-E.2    Karlberg, L.3    Nordgren, H.4    Bergh, A.5
  • 4
    • 0030972740 scopus 로고    scopus 로고
    • Expression of the apoptosis suppressing protein bcl-2 in prostatic adenocarcinoma is related to tumor malignancy
    • Lipponen P, Vesalainen S. Expression of the apoptosis suppressing protein bcl-2 in prostatic adenocarcinoma is related to tumor malignancy. Prostate. 1997;3:9-15.
    • (1997) Prostate , vol.3 , pp. 9-15
    • Lipponen, P.1    Vesalainen, S.2
  • 5
    • 0027093255 scopus 로고
    • Expression of the protooncogene bcl-2 in the prostate and its association with emergence of androgen-independent prostate cancer
    • McDonnell TJ, Troncoso P, Brisbay SM, et al. Expression of the protooncogene bcl-2 in the prostate and its association with emergence of androgen-independent prostate cancer. Cancer Res. 1992;52:6940-6944.
    • (1992) Cancer Res , vol.52 , pp. 6940-6944
    • McDonnell, T.J.1    Troncoso, P.2    Brisbay, S.M.3
  • 6
    • 0027773015 scopus 로고
    • Detection of the apoptosis-suppressing oncoprotein bcl-2 in hormone-refractory human prostate cancers
    • Colombel M, Symmans F, Gil S, et al. Detection of the apoptosis-suppressing oncoprotein bcl-2 in hormone-refractory human prostate cancers. Am J Pathol. 1993;143: 390-400.
    • (1993) Am J Pathol , vol.143 , pp. 390-400
    • Colombel, M.1    Symmans, F.2    Gil, S.3
  • 7
    • 0029851180 scopus 로고    scopus 로고
    • Bcl-2 overexpression combined with p53 protein accumulation correlates with hormone-refractory prostate cancer
    • Apakama I, Robinson MC, Walter NM, et al. Bcl-2 overexpression combined with p53 protein accumulation correlates with hormone-refractory prostate cancer. Br J Cancer. 1996;74:1258-1262.
    • (1996) Br J Cancer , vol.74 , pp. 1258-1262
    • Apakama, I.1    Robinson, M.C.2    Walter, N.M.3
  • 9
    • 0032698145 scopus 로고    scopus 로고
    • Apoptosis, mitosis, p53, bcl2, ki-67 and clinical outcome in prostate carcinoma treated by androgen ablation
    • Szende B, Romics I, Torda I, Bély M, Szegedi Zs, Lovász S. Apoptosis, mitosis, p53, bcl2, ki-67 and clinical outcome in prostate carcinoma treated by androgen ablation. Urol Int. 1999;63:115-119.
    • (1999) Urol Int , vol.63 , pp. 115-119
    • Szende, B.1    Romics, I.2    Torda, I.3    Bély, M.4    Szegedi, Zs.5    Lovász, S.6
  • 10
    • 0032871812 scopus 로고    scopus 로고
    • Effect of bcl-2 overexpression in human prostate cancer cells in vitro and in vivo
    • Kajiwara T, Takeuchi T, Ueki T, et al. Effect of bcl-2 overexpression in human prostate cancer cells in vitro and in vivo. Int J Urol. 1999;6:520-525.
    • (1999) Int J Urol , vol.6 , pp. 520-525
    • Kajiwara, T.1    Takeuchi, T.2    Ueki, T.3
  • 11
    • 0031034951 scopus 로고    scopus 로고
    • Bcl-2 expression confers androgen independence in androgen sensitive prostatic carcinoma
    • Westin P, Lo P, Marin CM, et al. Bcl-2 expression confers androgen independence in androgen sensitive prostatic carcinoma. Int J Oncol. 1997;10:113-118.
    • (1997) Int J Oncol , vol.10 , pp. 113-118
    • Westin, P.1    Lo, P.2    Marin, C.M.3
  • 12
    • 0032785072 scopus 로고    scopus 로고
    • Targeting bcl-2 gene to delay androgen-independent progression and enhance chemosensitivity in prostate cancer using antisense bcl-2 oligodeoxynucleotides
    • Gleave ME, Miayake H, Goldie J, Nelson C, Tolcher A. Targeting bcl-2 gene to delay androgen-independent progression and enhance chemosensitivity in prostate cancer using antisense bcl-2 oligodeoxynucleotides. Urology. 1999;54:36-46.
    • (1999) Urology , vol.54 , pp. 36-46
    • Gleave, M.E.1    Miayake, H.2    Goldie, J.3    Nelson, C.4    Tolcher, A.5
  • 13
    • 0033567003 scopus 로고    scopus 로고
    • Antisense bcl-2 oligodeoxynucleotides inhibit progression in androgen-independence after castration in the Shionogi tumor model
    • Miyake H, Tolcher A, Gleave ME. Antisense bcl-2 oligodeoxynucleotides inhibit progression in androgen-independence after castration in the Shionogi tumor model. Cancer Res. 1999;59:4030-4034.
    • (1999) Cancer Res , vol.59 , pp. 4030-4034
    • Miyake, H.1    Tolcher, A.2    Gleave, M.E.3
  • 14
    • 0030008078 scopus 로고    scopus 로고
    • Prognostic significance of bcl-2 in clinically localized prostate cancer
    • Bubendorf L, Sauter G, Moch H, et al. Prognostic significance of bcl-2 in clinically localized prostate cancer. Am J Pathol. 1996;148:1557-1565.
    • (1996) Am J Pathol , vol.148 , pp. 1557-1565
    • Bubendorf, L.1    Sauter, G.2    Moch, H.3
  • 15
    • 0029819406 scopus 로고    scopus 로고
    • Protein expression of p53, bcl-2, and KI-67 (MIB-1) as prognostic biomarkers in patients with surgically treated, clinically localized prostate cancer
    • Moul JW, Bettencourt MC, Sesterhenn IA, et al. Protein expression of p53, bcl-2, and KI-67 (MIB-1) as prognostic biomarkers in patients with surgically treated, clinically localized prostate cancer. Surgery. 1996;120:159-166.
    • (1996) Surgery , vol.120 , pp. 159-166
    • Moul, J.W.1    Bettencourt, M.C.2    Sesterhenn, I.A.3
  • 16
    • 0030829938 scopus 로고    scopus 로고
    • Combined analysis with bcl-2 and p53 immunostaining predicts poorer prognosis in prostatic carcinoma
    • Matsushima H, Kitamura T, Goto T, Hosaka Y, Homma Y, Kawabe K. Combined analysis with bcl-2 and p53 immunostaining predicts poorer prognosis in prostatic carcinoma. J Urol. 1997;158:2278-2283.
    • (1997) J Urol , vol.158 , pp. 2278-2283
    • Matsushima, H.1    Kitamura, T.2    Goto, T.3    Hosaka, Y.4    Homma, Y.5    Kawabe, K.6
  • 17
    • 0032699925 scopus 로고    scopus 로고
    • P53 and bcl-2 immunohistochemistry in pretreatment prostate needle biopsies to predict recurrence of prostate cancer after radical prostatectomy
    • Stackhouse GB, Sesterhenn IA, Bauer JJ, et al. P53 and bcl-2 immunohistochemistry in pretreatment prostate needle biopsies to predict recurrence of prostate cancer after radical prostatectomy. J Urol. 1999;162:2040-2045.
    • (1999) J Urol , vol.162 , pp. 2040-2045
    • Stackhouse, G.B.1    Sesterhenn, I.A.2    Bauer, J.J.3
  • 18
    • 0032853502 scopus 로고    scopus 로고
    • Preoperative p53, bcl-2, CD44 and e-cadherin immunohistochemistry as predictors of biochemical relapse after radical prostatectomy
    • Brewster SF, Oxley JD, Trivella M, Abbott CD, Gillatt DA. Preoperative p53, bcl-2, CD44 and e-cadherin immunohistochemistry as predictors of biochemical relapse after radical prostatectomy. J Urol. 1999;162:1238-1243.
    • (1999) J Urol , vol.162 , pp. 1238-1243
    • Brewster, S.F.1    Oxley, J.D.2    Trivella, M.3    Abbott, C.D.4    Gillatt, D.A.5
  • 19
    • 0030967596 scopus 로고    scopus 로고
    • P53, bcl-2 and retinoblastoma proteins as long-term prognostic markers in localized carcinoma of the prostate
    • Theodorescu D, Broder SF, Boyd JC, Mills SE, Frierson HF Jr. P53, bcl-2 and retinoblastoma proteins as long-term prognostic markers in localized carcinoma of the prostate. J Urol. 1997;158:131-137.
    • (1997) J Urol , vol.158 , pp. 131-137
    • Theodorescu, D.1    Broder, S.F.2    Boyd, J.C.3    Mills, S.E.4    Frierson H.F., Jr.5
  • 20
    • 0033897377 scopus 로고    scopus 로고
    • p53 accumulation associated with bcl-2, the proliferation marker MIB-1 and survival in patients with prostate cancer subjected to watchful waiting
    • Borre M, Stausbøl-Grøn B, Overgaard J. p53 accumulation associated with bcl-2, the proliferation marker MIB-1 and survival in patients with prostate cancer subjected to watchful waiting. J Urol. 2000;164:716-721.
    • (2000) J Urol , vol.164 , pp. 716-721
    • Borre, M.1    Stausbøl-Grøn, B.2    Overgaard, J.3
  • 21
    • 0032416157 scopus 로고    scopus 로고
    • Predictive value of bcl-2 immunoreactivity in prostate cancer patients treated with radiotherapy
    • Bylund A, Stattin P, Widmark A, Bergh A. Predictive value of bcl-2 immunoreactivity in prostate cancer patients treated with radiotherapy. Radiother Oncol. 1998;49:143-148.
    • (1998) Radiother Oncol , vol.49 , pp. 143-148
    • Bylund, A.1    Stattin, P.2    Widmark, A.3    Bergh, A.4
  • 22
    • 0032402183 scopus 로고    scopus 로고
    • Bcl-2/bax ratio as a predictive marker for therapeutic response to radiotherapy in patients with prostate cancer
    • Mackey TJ, Borkowski A, Amin P, Jacobs SC, Kyprianou N. Bcl-2/bax ratio as a predictive marker for therapeutic response to radiotherapy in patients with prostate cancer. Urology. 1998;52:1085-1090.
    • (1998) Urology , vol.52 , pp. 1085-1090
    • Mackey, T.J.1    Borkowski, A.2    Amin, P.3    Jacobs, S.C.4    Kyprianou, N.5
  • 23
    • 0032828118 scopus 로고    scopus 로고
    • Bcl-2 and p53 expression in clinically localized prostate cancer predicts response to external beam radiotherapy
    • Scherr DS, Vaughan ED Jr., Wei J, et al. Bcl-2 and p53 expression in clinically localized prostate cancer predicts response to external beam radiotherapy. J Urol. 1999;162: 12-17.
    • (1999) J Urol , vol.162 , pp. 12-17
    • Scherr, D.S.1    Vaughan E.D., Jr.2    Wei, J.3
  • 24
    • 0034991759 scopus 로고    scopus 로고
    • Apoptosis and bcl-2 expression in prostate cancer: Significance in clinical outcome after brachytherapy
    • Szostak MJ, Kaur P, Amin P, Jacobs SC, Kyprianou N. Apoptosis and bcl-2 expression in prostate cancer: significance in clinical outcome after brachytherapy. J Urol. 2001;165(6 Pt 1):2126-2130.
    • (2001) J Urol , vol.165 , Issue.6 PART 1 , pp. 2126-2130
    • Szostak, M.J.1    Kaur, P.2    Amin, P.3    Jacobs, S.C.4    Kyprianou, N.5
  • 25
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
    • Oltvai ZN, Milliman CL, Korsmeyer SJ. Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell. 1993;74:609-619.
    • (1993) Cell , vol.74 , pp. 609-619
    • Oltvai, Z.N.1    Milliman, C.L.2    Korsmeyer, S.J.3
  • 26
    • 0035136282 scopus 로고    scopus 로고
    • Adenovirus-mediated Bax overexpression for the induction of therapeutic apoptosis in prostate cancer
    • Li X, Marani M, Yu J, et al. Adenovirus-mediated Bax overexpression for the induction of therapeutic apoptosis in prostate cancer. Cancer Res. 2001;61:186-191.
    • (2001) Cancer Res , vol.61 , pp. 186-191
    • Li, X.1    Marani, M.2    Yu, J.3
  • 27
    • 0027282044 scopus 로고
    • bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death
    • Boise LH, Gonzalez-Garcia M, Postema CE, et al. bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death. Cell. 1993;74:597-608.
    • (1993) Cell , vol.74 , pp. 597-608
    • Boise, L.H.1    Gonzalez-Garcia, M.2    Postema, C.E.3
  • 29
    • 0029097470 scopus 로고
    • Multiple Bcl-2 family members demonstrate selective dimerizations with Bax
    • Sedlak TW, Oltvai ZN, Yang E, et al. Multiple Bcl-2 family members demonstrate selective dimerizations with Bax. Proc Natl Acad Sci USA. 1995;92:7834-7838.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 7834-7838
    • Sedlak, T.W.1    Oltvai, Z.N.2    Yang, E.3
  • 30
    • 0028972469 scopus 로고
    • A recombinant bcl-Xs adenovirus selectively induces apoptosis in cancer cells but not in normal bone marrow cells
    • Clarke MF, Apel IJ, Benedict MA, et al. A recombinant bcl-Xs adenovirus selectively induces apoptosis in cancer cells but not in normal bone marrow cells. Proc Natl Acad Sci USA. 1995;92:11024-11028.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 11024-11028
    • Clarke, M.F.1    Apel, I.J.2    Benedict, M.A.3
  • 31
    • 0029919668 scopus 로고    scopus 로고
    • Immunohistochemical analysis of bcl-2, bax, bcl-X, and mcl-1 expression in prostate cancers
    • Krajewska M, Krajewski S, Epstein JI, et al. Immunohistochemical analysis of bcl-2, bax, bcl-X, and mcl-1 expression in prostate cancers. Am J Pathol. 1996;148:1567-1576.
    • (1996) Am J Pathol , vol.148 , pp. 1567-1576
    • Krajewska, M.1    Krajewski, S.2    Epstein, J.I.3
  • 32
    • 0031757941 scopus 로고    scopus 로고
    • Expression of bcl-2, bax, and p53 in high grade prostatic intraepithelial neoplasia and localized prostate cancer: Relationship with apoptosis and proliferation
    • Johnson MI, Robinson MC, Marsh C, Robson CN, Neal DE, Hamdy FC. Expression of bcl-2, bax, and p53 in high grade prostatic intraepithelial neoplasia and localized prostate cancer: relationship with apoptosis and proliferation. Prostate. 1998;37:223-229.
    • (1998) Prostate , vol.37 , pp. 223-229
    • Johnson, M.I.1    Robinson, M.C.2    Marsh, C.3    Robson, C.N.4    Neal, D.E.5    Hamdy, F.C.6
  • 33
    • 0033821939 scopus 로고    scopus 로고
    • Prostate tumors from an Asian population: Examination of bxa, bcl-2, p53 and ras and identification of bax as a prognostic marker
    • Chia SJ, Tang WY, Elnatan J, Yap WM, Goh HS, Smith DR. Prostate tumors from an Asian population: examination of bxa, bcl-2, p53 and ras and identification of bax as a prognostic marker. Br J Cancer. 2000;83:761-768.
    • (2000) Br J Cancer , vol.83 , pp. 761-768
    • Chia, S.J.1    Tang, W.Y.2    Elnatan, J.3    Yap, W.M.4    Goh, H.S.5    Smith, D.R.6
  • 34
    • 0034635952 scopus 로고    scopus 로고
    • Bax degradation by the ubiquitin/proteasome-dependent pathway: Involvement in tumor survival and progression
    • Li B, Dou QP. Bax degradation by the ubiquitin/proteasome-dependent pathway: involvement in tumor survival and progression. Proc Natl Acad Sci USA. 2000;97:3850-3855.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 3850-3855
    • Li, B.1    Dou, Q.P.2
  • 35
    • 0033805413 scopus 로고    scopus 로고
    • IL-2, its receptors, and bcl-2 and bax genes in normal, hyperplastic and carcinomatous human prostates: Immunohistochemical comparative analysis
    • Royela M, De Miguel MP, Bethencourt FR, Fraile B, Arenas MI, Paniagua R. IL-2, its receptors, and bcl-2 and bax genes in normal, hyperplastic and carcinomatous human prostates: immunohistochemical comparative analysis. Growth Factors. 2000;18:135-146.
    • (2000) Growth Factors , vol.18 , pp. 135-146
    • Royela, M.1    De Miguel, M.P.2    Bethencourt, F.R.3    Fraile, B.4    Arenas, M.I.5    Paniagua, R.6
  • 36
    • 0036096949 scopus 로고    scopus 로고
    • Ki-67 staining is an independent correlate of biochemical failure in prostate cancer treated with radiotherapy
    • Cowen D, Troncoso P, Khoo VS, et al. Ki-67 staining is an independent correlate of biochemical failure in prostate cancer treated with radiotherapy. Clin Cancer Res. 2002;8: 1148-1154.
    • (2002) Clin Cancer Res , vol.8 , pp. 1148-1154
    • Cowen, D.1    Troncoso, P.2    Khoo, V.S.3
  • 37
    • 0034554795 scopus 로고    scopus 로고
    • Preliminary results of a randomized radiotherapy dose-escalation study comparing 70 Gy with 78 Gy for prostate cancer
    • Pollack A, Zagars GK, Smith LG, et al. Preliminary results of a randomized radiotherapy dose-escalation study comparing 70 Gy with 78 Gy for prostate cancer. J Clin Oncol. 2000;18:3904-3911.
    • (2000) J Clin Oncol , vol.18 , pp. 3904-3911
    • Pollack, A.1    Zagars, G.K.2    Smith, L.G.3
  • 39
    • 0032727673 scopus 로고    scopus 로고
    • Relationship of Ki-67 labeling index to DNA-ploidy, S-phase fraction, and outcome in prostate cancer treated with radiotherapy
    • Khoo VS, Pollack A, Cowen D, et al. Relationship of Ki-67 labeling index to DNA-ploidy, S-phase fraction, and outcome in prostate cancer treated with radiotherapy. Prostate. 1999;41:166-172.
    • (1999) Prostate , vol.41 , pp. 166-172
    • Khoo, V.S.1    Pollack, A.2    Cowen, D.3
  • 40
    • 0030813388 scopus 로고    scopus 로고
    • Abnormal bcl-2 and pRb expression are independent correlates of radiation response in muscle-invasive bladder cancer
    • Pollack A, Wu CS, Czerniak B, et al, Abnormal bcl-2 and pRb expression are independent correlates of radiation response in muscle-invasive bladder cancer. Clin Cancer Res. 1997;3: 1823-1829.
    • (1997) Clin Cancer Res , vol.3 , pp. 1823-1829
    • Pollack, A.1    Wu, C.S.2    Czerniak, B.3
  • 41
    • 0030906817 scopus 로고    scopus 로고
    • Consensus statement: Guidelines for PSA following radiation therapy
    • American Society for Therapeutic Radiology and Oncology Consensus Panel. Consensus statement: guidelines for PSA following radiation therapy. Int J Radiat Oncol Biol Phys. 1997;37:1035-1041.
    • (1997) Int J Radiat Oncol Biol Phys , vol.37 , pp. 1035-1041
  • 44
    • 0032817236 scopus 로고    scopus 로고
    • A recombinant defective adenoviral agent expressing anti-bcl-2 ribozyme promotes apoptosis of bcl-2-expressing human prostate cancer cells
    • Dorai T, Perlman H, Walsh K, et al. A recombinant defective adenoviral agent expressing anti-bcl-2 ribozyme promotes apoptosis of bcl-2-expressing human prostate cancer cells. Int J Cancer. 1999;82:846-852.
    • (1999) Int J Cancer , vol.82 , pp. 846-852
    • Dorai, T.1    Perlman, H.2    Walsh, K.3
  • 45
    • 0020442231 scopus 로고
    • Intestinal cell radiosensitivity: A comparison for cell death assayed by apoptosis or by a loss of clonogenicity
    • Hendry JH, Potten CS. Intestinal cell radiosensitivity: a comparison for cell death assayed by apoptosis or by a loss of clonogenicity. Int J Radiat Biol Relat Stud Phys Chem Med. 1982;42:621-628.
    • (1982) Int J Radiat Biol Relat Stud Phys Chem Med , vol.42 , pp. 621-628
    • Hendry, J.H.1    Potten, C.S.2
  • 46
    • 0030805690 scopus 로고    scopus 로고
    • Supraadditive apoptotic response of R3327-G rat prostate tumors to androgen ablation and radiation
    • Lim Joon D, Hasegawa M, Sikes C, et al. Supraadditive apoptotic response of R3327-G rat prostate tumors to androgen ablation and radiation. Int J Radiat Oncol Biol Phys. 1997;38:1071-1077.
    • (1997) Int J Radiat Oncol Biol Phys , vol.38 , pp. 1071-1077
    • Lim Joon, D.1    Hasegawa, M.2    Sikes, C.3
  • 47
    • 0031045967 scopus 로고    scopus 로고
    • Bcl-2 overexpression delays radiation-induced apoptosis without affecting the clonogenic survival of human prostate cancer cells
    • Kyprianou N, King ED, Bradbury D, Rhee JG. Bcl-2 overexpression delays radiation-induced apoptosis without affecting the clonogenic survival of human prostate cancer cells. Int J Cancer. 1997;70:341-348.
    • (1997) Int J Cancer , vol.70 , pp. 341-348
    • Kyprianou, N.1    King, E.D.2    Bradbury, D.3    Rhee, J.G.4
  • 48
    • 0033981306 scopus 로고    scopus 로고
    • The early supra-additive apoptotic response of R3327-G prostate tumors to androgen ablation and radiation is not sustained with multiple fractions
    • Pollack A, Ashoori F, Sikess C, et al. The early supra-additive apoptotic response of R3327-G prostate tumors to androgen ablation and radiation is not sustained with multiple fractions. Int J Radiat Oncol Biol Phys. 1999;46:153-158.
    • (1999) Int J Radiat Oncol Biol Phys , vol.46 , pp. 153-158
    • Pollack, A.1    Ashoori, F.2    Sikess, C.3
  • 49
    • 0035889395 scopus 로고    scopus 로고
    • Lack of prostate cancer radiosensitization by androgen deprivation
    • Pollack A, Salem N, Ashoori F, et al. Lack of prostate cancer radiosensitization by androgen deprivation. Int J Radiat Oncol Biol Phys. 2001;51:1002-1007.
    • (2001) Int J Radiat Oncol Biol Phys , vol.51 , pp. 1002-1007
    • Pollack, A.1    Salem, N.2    Ashoori, F.3
  • 50
    • 0025751550 scopus 로고
    • bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes
    • Sentman CL, Shutter JR, Hockenbery D, Kanagawa O, Korsmeyer SJ. bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes. Cell. 1991;67:879-888.
    • (1991) Cell , vol.67 , pp. 879-888
    • Sentman, C.L.1    Shutter, J.R.2    Hockenbery, D.3    Kanagawa, O.4    Korsmeyer, S.J.5
  • 51
  • 52
    • 0031691437 scopus 로고    scopus 로고
    • Expression of bcl-2, p53, and p21 in benign and malignant prostatic tissue before and after radiation therapy
    • Rakozy C, Grignon DJ, Sarkar FH, Sakr WA, Littrup P, Forman J. Expression of bcl-2, p53, and p21 in benign and malignant prostatic tissue before and after radiation therapy. Mod Pathol. 1998;11:892-899.
    • (1998) Mod Pathol , vol.11 , pp. 892-899
    • Rakozy, C.1    Grignon, D.J.2    Sarkar, F.H.3    Sakr, W.A.4    Littrup, P.5    Forman, J.6
  • 53
    • 0032458445 scopus 로고    scopus 로고
    • Locally recurrent prostate tumors following either radiation therapy or radical prostatectomy have changes in Ki-67 labeling index, p53 and bcl-2 immunoreactivity
    • Grossfeld GD, Olumi AF, Connolly JA, et al. Locally recurrent prostate tumors following either radiation therapy or radical prostatectomy have changes in Ki-67 labeling index, p53 and bcl-2 immunoreactivity. J Urol. 1998;159:1437-1443.
    • (1998) J Urol , vol.159 , pp. 1437-1443
    • Grossfeld, G.D.1    Olumi, A.F.2    Connolly, J.A.3
  • 54
    • 0034636443 scopus 로고    scopus 로고
    • The impact of bcl-2 expression and bax deficiency on prostate homeostasis in vivo
    • Bruckheimer EM, Cho S, Brisbay S, et al. The impact of bcl-2 expression and bax deficiency on prostate homeostasis in vivo. Oncogene. 2000;19:2404-2412.
    • (2000) Oncogene , vol.19 , pp. 2404-2412
    • Bruckheimer, E.M.1    Cho, S.2    Brisbay, S.3


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