Knockout of the intermediate filament protein CP49 destabilises the lens fibre cell cytoskeleton and decreases lens optical quality, but does not induce cataract

Experimental Eye Research

Volumn 76, Issue 3, 2003, Pages 385-391

  Sandilands, Aileen ^a   Prescott, Alan R ^b   Wegener, Alfred ^c   Zoltoski, Rebecca K ^d   Hutcheson, Aileen M ^b   Masaki, Shigeo ^e   Kuszak, Jer R ^f   Quinlan, Roy A ^g  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b UNIVERSITY OF DUNDEE   (United Kingdom)

^c UNIVERSITY OF BONN   (Germany)

^d ILLINOIS COLLEGE OF OPTOMETRY   (United States)

^e INSTITUTE FOR DEVELOPMENTAL RESEARCH   (Japan)

^f RUSH UNIVERSITY MEDICAL CENTER   (United States)

^g DURHAM UNIVERSITY   (United Kingdom)

Author keywords

Beaded filament; Cataract; Cytoskeleton; Intermediate filament; Knockout; Lens

Indexed keywords

INTERMEDIATE FILAMENT PROTEIN; PROTEIN CP49; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CATARACT; CELL MEMBRANE; CONTROLLED STUDY; CYTOSKELETON; GENETIC ANALYSIS; KNOCKOUT MOUSE; LENS; LENS EPITHELIUM; LENS FIBER; LIGHT SCATTERING; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN ANALYSIS;

EID: 0037373876     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-4835(02)00330-5     Document Type: Article

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