The RHOad less traveled: The myosin phosphorylation-independent path from Rho kinase to cell contraction. Focus on "Rho kinase mediates serum-induced contraction in fibroblast fibers independent of myosin LC20 phosphorylation"

American Journal of Physiology - Cell Physiology

Volumn 284, Issue 3 53-3, 2003, Pages

  Seasholtz, Tammy M ^a  

^a San Diego   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; ELONGATION FACTOR 1ALPHA; F ACTIN; GROWTH FACTOR; KT 5926; LYSOPHOSPHATIDIC ACID; MYOSIN LIGHT CHAIN KINASE; MYOSIN LIGHT CHAIN KINASE INHIBITOR; PERTUSSIS TOXIN; PLATELET DERIVED GROWTH FACTOR; RHO KINASE;

ANIMAL TISSUE; CELL TYPE; EDITORIAL; ENZYME PHOSPHORYLATION; FIBROBLAST; NONHUMAN; PRIORITY JOURNAL; SMOOTH MUSCLE CONTRACTILITY; SMOOTH MUSCLE CONTRACTION; SMOOTH MUSCLE FIBER;

ANIMALIA;

EID: 0037370706     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.00530.2002     Document Type: Editorial

References (23)

1. Amano M, Ito M, Kimura K, Fukata Y, Chihara K, Nakano T, Matsuura Y, and Kaibuchi K. Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase). J Biol Chem 271: 20246-20249, 1996.
2. Chrzanowska-Wodnicka M and Burridge K. Rho-stimulated contractility drives the formation of stress fibers and focal adhesions. J Cell Biol 133: 1403-1415, 1996.
3. 2+ sensitization of smooth muscle. J Biol Chem 272: 10704-10709, 1997.
4. Grinnell F, Ho CH, Lin YC, and Skuta G. Differences in the regulation of fibroblast contraction of floating versus stressed collagen matrices. J Biol Chem 274: 918-923, 1999.
5. Guidry C. Fibroblast contraction of collagen gels requires activation of protein kinase c. J Cell Physiol 155: 358-367, 1993.
6. Hirata KI, Kikuchi A, Sasaki T, Kuroda S, Kaibuchi K, Matsuura Y, Seki H, Saida K, and Takai Y. Involvement of rho p21 in the GTP-enhanced calcium ion sensitivity of smooth muscle contraction. J Biol Chem 267: 8719-8722, 1992.
7. Izawa T, Fukata Y, Kimura T, and Iwamatsu A. Elongation Factor-la is a novel substrate of Rho-associated kinase. Biochem Biophys Res Commun 278: 72-78, 2000.
8. Kawano Y, Fukata Y, Oshiro N, Amano M, Nakamura T, Ito M, Matsumura F, Inagaki M, and Kaibuchi K. Phosphorylation of myosin-binding subunit (MBS) of myosin phosphatase by Rho-kinase in vivo. J Cell Biol 147: 1023-1038, 1999.
9. Kimura K, Fukata Y, Matsuoka Y, Bennett V, Matsuura Y, Okawa K, Iwamatsu A, and Kaibuchi K. Regulation of the association of adducin with actin filaments by Rho-associated kinase (Rho-kinase) and myosin phosphatase. J Biol Chem 273: 5542-5548, 1998.
10. Kimura K, Ito M, Amano M, Chihara K, Fukata Y, Nakafuku M, Yamamori B, Feng J, Nakano T, Okawa K, Iwamatsu A, and Kaibuchi K. Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase). Science 273: 245-248, 1996.
11. 2+. J Biol Chem 264: 5339-5342, 1989.
12. 2+-sensitization. Eur J Pharmacol 290: 19-27, 1995.
13. 2+-independent myosin II phosphorylation and contraction in chicken embryo fibroblasts. J Physiol 515: 87-92, 1999.
14. Kureishi Y, Kobayashi S, Amano M, Kimura K, Kanaide H, Nakano T, Kaibuchi K, and Ito M. Rho-associated kinase directly induces smooth muscle contraction through myosin light chain phosphorylation. J Biol Chem 272: 12257-12260, 1997.
15. Maekawa M, Ishizaki T, Boku S, Watanabe N, Fujita A, Iwamatsu A, Obinata T, Ohashi K, Mizuno K, and Narumiya S. Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase. Science 285: 895-898, 1999.
16. 2+ sensitivity in α-toxin permeabilized arterial smooth muscle. Biochem Biophys Res Commun 157: 677-683, 1988.
17. Nobe H, Nobe K, Fazal F, de Lanerolle P., and Paul RJ. Rho kinase mediates serum-induced contraction in fibroblast fibers independent of myosin LC20 phosphorylation. Am J Physiol Cell Physiol 284: C599-C606, 2003.
18. Noda M, Yasuda-Fukazawa C, Moriishi K, Kato T, Okuda T, Kurokawa K, and Takuwa Y. Involvement of rho in GTPγS-induced enhancement of phosphorylation of 20 kDa myosin light chain in vascular smooth muscle cells: inhibition of phosphatase activity. FEBS Lett 367: 246-250, 1995.
19. Obara K, Nikcevic G, Pestic L, Nowak G, Lorimer DD, Guerriero V Jr, Elson EL, Paul RJ, and de Lanerolle P. Fibroblast contractility without an increase in basal myosin light chain phosphorylation in wild type cells and cells expressing the catalytic domain of myosin light chain kinase. J Biol Chem 270: 18734-18737, 1995.
20. i and contractility in a reconstituted fibroblast fiber. Am J Physiol Cell Physiol 279: C785-C796, 2000.
21. Skuta G, Ho CH, and Grinnell F. Increased myosin light chain phosphorylation is not required for growth factor stimulation of collagen matrix contraction. J Biol Chem 274: 30163-30168, 1999.
22. Yee HF Jr, Melton AC, and Tran BN. RhoA/rho-associated kinase mediates fibroblast contractile force generation. Biochem Biophys Res Commun 280: 1340-1345, 2001.
23. Yonemura S, Matsui T, Tsukita S, and Tsukita S. Rho-dependent and -independent activation mechanisms of ezrin/radixin/moesin proteins: an essential role for polyphosphoinositides in vivo. J Cell Sci 115: 2569-2580, 2002.