Effect of leptin administration on plasma and tissue lipids in alcohol induced liver injury

Human and Experimental Toxicology

Volumn 22, Issue 3, 2003, Pages 149-154

  Balasubramaniyan, V ^a   Manju, V ^a   Nalini, N ^a  

^a ANNAMALAI UNIVERSITY   (India)

Author keywords

Alcohol; Hepatotoxicology; Leptin; Lipids

Indexed keywords

ALCOHOL; FATTY ACID; LIPID; PHOSPHOLIPID; RECOMBINANT LEPTIN; TRIACYLGLYCEROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; FATTY ACID BLOOD LEVEL; FOOD INTAKE; HYPERLIPIDEMIA; LIPID BLOOD LEVEL; LIPID STORAGE; LIVER INJURY; LIVER TOXICITY; MALE; MOUSE; NONHUMAN; PHOSPHOLIPID BLOOD LEVEL; PRIORITY JOURNAL; SUPPLEMENTATION; TISSUE LEVEL; TRIACYLGLYCEROL BLOOD LEVEL; WEIGHT GAIN;

ANIMALS; ANTILIPEMIC AGENTS; FATTY ACIDS, NONESTERIFIED; LEPTIN; LIPID METABOLISM; LIPIDS; LIVER DISEASES, ALCOHOLIC; MALE; MICE; PHOSPHOLIPIDS; TRIGLYCERIDES; WEIGHT GAIN;

ANIMALIA;

EID: 0037367726     PISSN: 09603271     EISSN: None     Source Type: Journal    
DOI: 10.1191/0960327103ht337oa     Document Type: Article

References (31)

1. Avogaro P, Cazzolatu G. Changes in the composition and physiochemical characteristics of serum lipoproteins during ethanol induced lipidemia in alcoholic subjects. Metabolism 1975; 219: 1231-42.
2. Hirayama C, Nosaka Y, Yamada S, Yamanishi Y. Effect of chronic ethanol administration on serum high-density lipoprotein cholesterol in rats. Res Comm Chem Pathol Pharmacol 1979; 26: 563-69.
3. Hungard BL, Goldstein DB, Villegas F, Cooper T. The ganglioside GM 1 reduces ethanol induced phospholipase activity in synaptosomal preparation from mice. Neurochem Int 1988; 25: 321-25.
4. Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM. Positional cloning of the mouse obese gene and its human homologue. Nature 1994; 372: 425-32.
5. Laharrague P, Larrouy D, Fontanilles AM, Truel N, Campfield A, Tenenbaum R et al. High expression of leptin by human bone marrow adipocytes in primary culture. FASEB J 1998; 12: 747-52.
6. Hoggard N, Hunter L, Duncan JS, Williams LM, Trayhurn P, Mercer JG. Leptin and leptin receptor mRNA and protein expression in the murine fetus and placenta. Proc Natl Acad Sci USA 1997; 94: 11073-78.
7. Friedman-Einat M, Boswell T, Horev G, Girishvarma G, Dunn IC, Talbot RT et al. The chicken leptin gene: Has it been cloned? Gen Comp Endocrinol 1999; 115: 354-63.
8. Hamilton BS, Paglia D, Kwan AYM, Deital M. Increased obese mRNA expression in omental fat cells from massively obese humans. Nat Med 1995; 1: 953-56.
9. Maffei M, Halaas J, Ravussin E, Pratley RE, Lee GH, Zhang Y et al. Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects. Nat Med 1995; 1: 1155-61.
10. Hourigan LF, Macdonald GA, Purdie D, Whitehall VH, Shorthouse C, Clouston A et al. Fibrosis in chronic hepatitis C. correlates significantly with body mass index and steatosis. Hepatology 1999; 29: 1215-19.
11. Naveau S, Giraud V, Borotto E, Aubert A, Capron F, Chaput JC. Excess weight risk factor for alcoholic liver disease. Hepatology 1997; 25: 108-11.
12. Diehl AM. Nonalcoholic steatohepatitis. Seminars in Liver Disease 1999: 19: 221-29.
13. Considine RV, Sinha MK, Heiman ML, Kriauciunas A, Stephens TW, Nyce MR et al. Serum immunoreactive-leptin concentrations in normal weight and obese humans. N Engl J Med 1996; 334: 292-95.
14. Folch J, Less M, Stanly GHS. A simple method for the isolation and purification of total lipids from animal tissue. J Biol Chem 1957; 226: 497-509.
15. Zilversmit DB, Davis AK. Microdetermination of plasma phospholipid by TCA precipitation method. J Lab Clin Med 1950; 35: 155-60.
16. Foster CS, Dunn O. Stable reagents for determination of serum triglycerides by a colorimetric hantzsch condensation method. Clin Chim Acta 1973; 19: 338-40.
17. Falholt K, Falholt W, Lund B. An easy colorimetric method for routine determination of free fatty acids in plasma. Clin Chim Acta 1973; 46: 105-11.
18. Lowry OH, Roseborough MJ, Farr AL, Randall RJ. Protein measurement with Folin-phenol reagent. J Biol Chem 1951; 193: 265-75.
19. Fruhbeck G, Jebb SA, Prentice AM. Leptin: physiology and pathophysiology. Clin Physiol 1998; 18: 399-419.
20. Baile CA, Della-Fera MA, Martin RJ. Regulation of metabolism and body fat mass by leptin. Annu Rev Nutr 2000; 20: 105-27.
21. Erickson JC, Clegg KE, Palmiter RD. Sensitivity to leptin and susceptibility to seizures of mice lacking neuropeptide Y. Nature 1996; 381: 415-18.
22. Diamond FB Jr, Eichler DC. Leptin: molecular biology, physiology, and relevance to pediatric practice. Adv Pediatr 1999; 46: 151-87.
23. Leiber CS, Schmid R. The effect of ethanol on fatty acid metabolism: Stimulation of hepatic fatty acid synthesis in vitro. J Clin Invest 1961; 40: 394-99.
24. Godde WH, Agarwal DP. Alcoholism. Biomedical genetics aspects, first edition. New York: Pergamon Press,1981.
25. Remla A, Menon PVG, Kurup PA. Effect of ethanol administration on metabolism of lipids in heart and aorta in isoproterenol induced myocardial infarction in rats. Indian J Exp Biol 1991; 29: 244-48.
26. Lauterburg BH, Linag D, Schwarzenbach FA, Breen KJ. Mitochondrial dysfunction in alcoholic patients as assessed by breath analysis. Hepatology 1993; 17: 418-22.
27. Grunnet N, Kondrup J. Effects of ethanol on lipid metabolism in cultured hepatocytes. Biochem J 1985; 228: 673-81.
28. Chen G, Koyama K, Yuan X, Lee Y, Zhou YT, O'Doherty R et al. Disappearance of body fat in normal rats induced by adenovirus-mediated leptin gene therapy. Proc Natl Acad Sci USA 1996; 93: 14795-99.
29. Shannon PR, Jean-Michel W. Leptin: an essential regulator of lipid metabolism. Comp Biochem Physiol 2000; 125: 285-97.
30. Soukas A, Cohen P, Socci ND, Friedman JM. Leptin specific patterns of gene expression in white adipose tissue. Genes Dev 2000; 14: 963-80.
31. Wang M, Lee Y, Unger RH. Novel form of lipolysis induced by leptin. J Biol Chem 1999; 274: 17541-544.