Prolonged drug-induced hypothermia in experimental stroke

Journal of Stroke and Cerebrovascular Diseases

Volumn 12, Issue 2, 2003, Pages 97-102

  Johansen, Flemming Fryd ^a   Jørgensen, Henrik Stig ^b   Reith, Jakob ^b  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b NONE

Author keywords

Dopamine; Focal ischemia; Hypokalemia; Middle cerebral artery occlusion; Neuroprotection; Rat; Thermoregulation

Indexed keywords

DOPAMINE RECEPTOR STIMULATING AGENT; TALIPEXOLE;

ANIMAL MODEL; ARTICLE; BODY MOVEMENT; BODY TEMPERATURE; BRAIN INFARCTION; CEREBROVASCULAR DISEASE; CONTROLLED STUDY; DOPAMINERGIC SYSTEM; HYPOKALEMIA; INDUCED HYPOTHERMIA; MIDDLE CEREBRAL ARTERY OCCLUSION; NONHUMAN; PRIORITY JOURNAL; RAT; STROKE;

EID: 0037366410     PISSN: 10523057     EISSN: None     Source Type: Journal    
DOI: 10.1053/jscd.2003.14     Document Type: Article

References (48)

1. Busto R, Dietrich WD, Globus MY, et al. Small differences in intraischemic brain temperature critically determine the extent of ischemic neuronal injury. J Cereb Blood Flow Metab 1987;7:729-738.
2. Chen H, Chopp M, Zhang ZG, et al. The effect of hypothermia on transient middle cerebral artery occlusion in the rat. J Cereb Blood Flow Metab 1992;12:621-628.
3. Maher J, Hachinski V. Hypothermia as a potential treatment for cerebral ischemia. Cerebrovasc Brain Metab Rev 1993;5:277-300.
4. Johansen FF, Tonder N, Berg M, et al. Hypothermia protects somatostatinergic neurons in rat dentate hilus from zinc accumulation and cell death after cerebral ischemia. Mol Chem Neuropathol 1993;18:161-172.
5. Nurse S, Corbett D. Direct measurement of brain temperature during and after intraischemic hypothermia: correlation with behavioural, physiological and histiological endpoints. J Neurosci 1994;14:7726-7734.
6. De Keyser J. Antipyretics in acute ischemic stroke. Lancet 1998;352:6-7.
7. Hill MD, Hachinski V. Stroke treatment: time is brain. Lancet 1999;353:151-152.
8. Schwab S, Schwartz S, Spranger M, et al. Moderate hypothermia in the treatment of patients with severe middle cerebral artery infarction. Stroke 1998;29:2461-2466.
9. Kammersgaard LP, Rasmussen BH, Jørgensen HS, et al. Feasibility and safety of inducing modest hypothermia in awake patients with acute stroke through surface cooling: A case-control study. Stroke 2000;31:2251-2256.
10. Ginsberg MD, Busto R. Combating hyperthermia in acute stroke. A significant concern. Stroke 2000;29:529-534.
11. Dippel DWJ, van Breda EJ, van Gemert HMA, et al. Effect of paracetamol (acetominophen) on body temperature in acute ischemic stroke. Stroke 2001;32:1607.
12. The Hypothermia after Cardiac Arrest Study Group. Mild therapeutic hypothermia to improve the neurological outcome after cardiac arrest. N Engl J Med 2002;346: 549-556.
13. Bernard SA, Gray TW, Brist MD, et al. Treatment of comatose survivors of out of hospital cardiac arrest with induced hypothermia. N Engl J Med 2002;346:557-563.
14. Reith J, Jørgensen HS, Pedersen PM, et al. Body temperature in acute stroke: relation to stroke severity, infarct size, mortality, and outcome. Lancet 1996;347:422-429.
15. Jorgensen HS, Reith J, Pedersen PM, et al. Body temperature and outcome in stroke patients. Lancet 1996;348: 193.
16. De Keyser J, Sulter G, Luiten PG. Clinical trials with neuroprotective drugs in acute ischemic stroke: are we doing the right thing? Trends Neurosci 1999;22:535-540.
17. Lee J-M, Grabb MC, Zipfel GJ, et al. Brain tissue responses to ischemia. J Clin Invest 2000;106:723-731.
18. Venna A, Kulkarni SK. Dopamine receptor mediated hypothermic action of B-HT 920 in rats. J Pharm Pharmacol 1991;43:421-424.
19. Colboc O, Costentin J. Evidence for thermoregulatoty dopaminergic receptor located in the preopticus medialis nucleus of the rat hypothalamus. J Pharm Pharmacol 1980;32:624-629.
20. Sanchez C, Amt J. Effect on body temperature in mice differentiate between dopamine D2 receptor agonists with high and low efficacies. Eur J Pharmacol 1992;211: 9-14.
21. Anden NE, Golembiowska-Nikiten K, Thomström U. Selective stimulation of dopamine and noradrenaline autoreceptors by B-HT 920 and B-HT 933, respectively. Naunun Schmiedebergs Arch. Pharmacol 1982;32:100-104.
22. Tamura A, Graham DI, McCulluch J, et al. Focal cerebral ischemia in the rat: 1. Description of technique and early neuropathological consequences following middle cerebral artery occlusion. J Cereb Blood Flow Metab 1981;1:53-60.
23. Du C, Hu R, Csernansky CA, et al. Very delayed infarction after mild focal cerebral ischemia: A role for apoptosis? J Cereb Blood Flow Metab 1996;16:195-201.
24. Swanson RA, Morton MT, Tsao-Wu G, et al. A semiautomated method for measuring brain infarct volume. J Cereb Blood Flow Metab 1990;10:290-293.
25. Buchan A, Pulsinelli WA. Hypothermia but not the N-methyl-D-aspartate antagonist, MK-801, attenuates neuronal damage in gerbils subject to transient global ischemia. J Neurosci 1990;10:311-316.
26. Hall ED, Andrus PK, Pazara KE. Protective efficacy of a hypothermic pharmacological agent in gerbil forebrain ischemia. Stroke 1993;24:711-715.
27. Nurse S, Corbett D. Neuroprotection after several days of mild, drug-induced hypothermia. J Cereb Blood Flow Metab 1996;3:474-480.
28. Koth A, Cane R, Cerullo LJ. Serum potassium levels during prolonged hypothermia. Intensive Care Med 1983;9:275-277.
29. Sprung J, Cheng EY, Gamulin S, et al. Effects of acute hypothermia and beta-adrenergic receptor blockade on serum potassium concentration in rats. Crit Care Med 1991;19:1545-1551.
30. Clifton GL, Allen S, Berry J, et al. Systemic hypothermia in treatment of brain injury. J Neurotrauma 1992;9:487-495.
31. Azzapardi D, Robertson NJ, Cowan FM, et al. Pilot study of treatment with whole body hypothermia for neonatal encephalopathy. Pediatrics 2000;106:684-694.
32. Boelhouwer RU, Bruining HA, Ong GL. Correlation of serum potassium fluctuations with body temperature after major surgery. Crit Care Med 1987;15:310-312.
33. + and calcium content during in vivo stimulation of rat skeletal muscle. Acta Phys Scand 1993;147:1011-1022.
34. Oerther S. Temperature set-point changes induced by DA D2/3 and 5-HTî receptor agonist in the rat. Neuroreport 2000;11:3949-3951.
35. Coimbra C, Drake M, Boris-Möller F, et al. Long lasting neuroprotective effect of postischemic hypothermia and treatment with an anti-inflammatory/antipyretic drug. Evidence for chronic encephalopathic processes following ischemia. Stroke 1996;27:1578-1585.
36. Colbourne F, Corbett D. Functional and histological protection following prolonged postischemic hypothermia: a six month survival study. J Neurosci 1995;15:7250-7260.
37. Mellergard P. Changes in intracerebral temperature in response to different methods of brain cooling. Neurosurgery 1992;31:671-677.
38. Hunter AJ, Green AR, Cross AJ. Animal models of acute ischemic stroke: can they predict clinically successful neuroprotective drugs? Trends Pharmacol Sci 1995;16: 123-126.
39. Hu P, Diemer NH, Bruhn T, et al. Effect of the AMPA-receptor antagonist, NBQX, on neuron loss in dentate hilus of the hippocampal formation after 8, 10, or 12 minutes of cerebral ischemia in the rat. J Cereb Blood Flow Metab 1997;17:147-152.
40. Kast A, Ganz H, Frolke W. The oral toxicology of Talipexole in rhesus monkeys. Pharmacometrics 1993;45: 545-553.
41. Clark WG, Clark YL. Changes in body temperature after administration of antipyretics, LSD, Ag-TCH, CNS depressants and stimulants, hormones, inorganic ions, gases,2,4-DNP and miscellaneous agents. Neurosci Biobehav Res 1981;5:1-136.
42. Koennecke H-C, Leistner S. Prophylactic antipyretic treatment with acetominophen in acute ischemic stroke: A pilot study. Neurology 2001;57:2301-2303.
43. Kasner SE, Wein T, Piriwat P, et al. Acetominophen for altering body temperature in acute stroke. Stroke 2002; 33:130-135.
44. Liu XH, Kato H, Chen T, et al. Bromocriptine protects agains delayed neuronal death of hippocampal neurons following cerebral ischemia in the gerbil. J Neurol Sci 1995;129:9-14.
45. Kitamura Y, Kosaka T, Kakimura J-I, et al. Protective effects of the antiparkinson drugs Talipexole and Pramipexole against 1-methyl-4-phenylpyridinium-induced apoptotic cell death in human neuroblastoma SH-SY5Y cells. Mol Pharmacology 1998;54:1046-1054.
46. Maier C, Steinberg GK, Sun GH, et al. Neuroprotection by the alpha2-adrenoreceptor agonist dexmedetomidine in a focal model of cerebral ischemia. Anesthesiology 1993;79:306-312.
47. Berkman MZ, Zirh TA, Berkman K, et al. Tizanidine is an effective agent in prevention of focal cerebral ischemia in rats: an experimental study. Surg Neurol 1998;50:264-270.
48. Jolkkonen J, Puurunen K, Koistinaho J, et al. Neuroprotection by the alpha2-adrenoreceptor agonist dexmedetomidine in rat focal cerebral ischemia. Eur J Pharmacol 1999;372:31-36.