The periodontal Ruffini endings in brain derived neurotrophic factor (BDNF) deficient mice

Archives of Histology and Cytology

Volumn 66, Issue 1, 2003, Pages 73-81

  Alkhamrah, Bashar Anas ^a   Hoshino, Natalia ^a   Kawano, Yoshiro ^a   Harada, Fumiko ^a   Hanada, Kooji ^a   Maeda, Takeyasu ^a  

^a NIIGATA UNIVERSITY GRADUATE SCHOOL OF MEDICAL AND DENTAL SCIENCES   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; GENE PRODUCT;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DENSITY; CONFOCAL MICROSCOPY; IMMUNOHISTOCHEMISTRY; INCISOR; INNERVATION; MECHANORECEPTOR; MOUSE; NERVE CELL; NERVE FIBER; NERVE GROWTH; NOCICEPTIVE RECEPTOR; NONHUMAN; PERIODONTAL LIGAMENT; QUANTITATIVE ANALYSIS; WILD TYPE;

ANIMALS; BRAIN-DERIVED NEUROTROPHIC FACTOR; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENOTYPE; HETEROZYGOTE; INCISOR; MECHANORECEPTORS; MICE; MICE, KNOCKOUT; PERIODONTAL LIGAMENT;

EID: 0037366320     PISSN: 09149465     EISSN: None     Source Type: Journal    
DOI: 10.1679/aohc.66.73     Document Type: Article

References (40)

1. Andres KH, von Düring M: Morphology of cutaneous receptors. In: Handbook of Sensory Physiology, Vol II. Somatosensory system (Iggo A, ed). Springer-Verlag, Berlin-Heidelberg-New York, 1972 (p. 3-28).
2. Asahito T, Ohshima H, Hanada K, Wakisaka S, Maeda T: Postnatal expression of calretinin-immunoreactivity in periodontal Ruffini endings in the rat incisor: a comparison with protein gene product 9.5 (PGP9.5)-immunoreactivity. Arch Histol Cytol 62: 57-69 (1999).
3. Atsumi Y, Hayashi S, Nakakura-Ohshima K, Maeda T, Kurisu K, Wakisaka S: Heterogeneous localizations of Trk B among individual periodontal Ruffini endings in the rat incisor. Arch Histol Cytol 62: 435-440 (1999).
4. Barde YA: Neurotrophins: a family of proteins supporting the survival of neurons. Prog Clin Biol Res 390: 45-56 (1994).
5. Beertsen W, Everts V, van den Hooff A: Fine structure and possible function of cells containing leptomergic organelles in the periodontal ligament of the rat incisor. Arch Oral Biol 19: 1099-1100 (1974).
6. Biemesderfer D, Munger BL, Binck J, Dubner R: The pilo-Ruffini complex: a non-sinus hair and associated slowly-adapting mechanoreceptor in primate facial skin. Brain Res 142: 197-222 (1978).
7. Bothwell M: Functional interactions of neurotrophins and neurotrophin receptors. Ann Rev Neurosci 18: 223-253 (1995).
8. Byers MR: Sensory innervation of periodontal ligament of rat molars consists of unencapsulated Ruffini-like mechanoreceptors and free nerve endings. J Comp Neurol 231: 500-518 (1985).
9. Carroll P, Lewin GR, Koltzenburg M, Toyka KV, Thoenen H: A role for BDNF in mechanosensation. Nat Neurosci 1: 42-46 (1998).
10. Chambers MR, Andres KH, von Düring M, Iggo A: Structure and function of the slowly adapting type II mechanoreceptor in hairy skin. Quart J Exp Physiol 57: 417-445 (1972).
11. Davies AM: Studies of neurotrophin biology in the developing trigeminal system. J Anat 191: 483-491 (1997).
12. Doran JF, Jackson P, Kynoch PA, Thompson RJ: Isolation of PGP 9.5, a new human neurone-specific protein detected by high-resolution two-dimensional electrophoresis. J Neurochem 40: 1542-1547 (1983).
13. Ernfors P, Lee KF, Kucera J, Jaenisch R: Lack of neurotrophin-3 leads to deficiencies in the peripheral nervous system and loss of limb proprioceptive afferents. Cell 20: 503-512 (1994a).
14. Ernfors P, Lee KF, Jaenisch R: Mice lacking brain-derived neurotrophic factor develop with sensory deficits. Nature 368: 147-150 (1994b).
15. Ernfors P, Kucera J, Lee KF, Loring J, Jaenisch R: Studies on the physiological role of brain-derived neurotrophic factor and neurotrophin-3 in knockout mice. Int J Dev Biol 39: 799-807 (1995a).
16. Ernfors P, Van de Water T, Loring J, Jaenisch R: Complementary roles of BDNF and NT-3 in vestibular and auditory development. Neuron 14: 1153-1164 (1995b).
17. Fundin BT, Silos-Santiago I, Ernfors P, Fagan AM, Aldskogius H, Dechiara TM, Phillips HS, Barbacid M, Yancopoulos GD, Rice FL: Differential dependency of cutaneous mechanoreceptors on neurotrophins, trk receptors, and P75 LNGFR. Dev Biol 190: 94-116 (1997).
18. Gulbenkian S, Wharton J, M. Polak J: The visualisation of cardiovascular innervation in the guinea pig using an antiserum to protein gene product 9.5 (PGP 9.5). J Auton Nerv Syst 18: 235-247 (1987).
19. Hannam AG: The innervation of the periodontal ligament. In: The periodontal ligament in health and disease. (Berkovitz BKB, Moxham BJ, Matthews B, ed) Pergamon Press, Oxford, 1982 (p. 173-196).
20. Jones KR, Farinas I, Backus C, Reichardt LF: Targeted disruption of the BDNF gene perturbs brain and sensory neuron development but not motor neuron development. Cell 76: 989-999 (1994).
21. Kapland R, Miller FD: Neurotrophin signal transduction in the nervous system. Curr Opin Neurobiol 10: 381-391 (2000).
22. Klein R, Nanduri V, Jing SA, Lamballe F, Tapley P, Bryant S, Cordon-Cardo C, Jones KR, Reichardt LF, Barbacid M: The trkB tyrosine protein kinase is a receptor for brain-derived neurotrophic factor and neurotrophin-3. Cell 66: 395-403 (1991).
23. Klein R, Lamballe F, Bryant S, Barbacid M: The trkB tyrosine protein kinase is a receptor for neurotrophin-4. Neuron 8: 947-956 (1992).
24. Lewin GR, Barde YA: Physiology of the neurotrophins. Ann Rev Neurosci 19: 289-317 (1996).
25. Liebl DJ, Tessarollo L, Palko ME, Parada LF: Absence of sensory neurons before target innervation in brain-derived neurotrophic factor-, neurotrophin 3-, and TrkC-deficient embryonic mice. J Neurosci 17: 9113-9121 (1997).
26. Liu X, Ernfors P, Wu H, Jaenisch R: Sensory but not motor neuron deficits in mice lacking NT4 and BDNF. Nature 375: 238-241 (1995).
27. Maeda T, Sato O, Kobayashi S, Iwanaga T, Fujita T: The ultrastructure of Ruffini endings in the periodontal ligament of rat incisors with special reference to the terminal Schwann cells (K-cells). Anat Rec 223: 95-103 (1989).
28. Maeda T, Ochi K, Nakakura-Ohshima K, Youn SH, Wakisaka S: The Ruffini ending as the primary mechanoreceptor in the periodontal ligament:its morphology, cytochemical features, regeneration, and development. Crit Rev Oral Biol Med 10: 307-327 (1999).
29. Matthews B: Mastication. In: Applied physiology of mouth (Lanelle CLB, ed), Wrights, Bristol, 1975 (p. 199-242).
30. Nakakura-Ohshima K, Maeda T, Sato O, Takano Y: Postnatal development of periodontal innervation in rat incisors: an immunohistochemical study using protein gene product 9.5 antibody. Arch Histol Cytol 56: 385-398 (1993).
31. Nakakura-Ohshima K, Maeda T, Ohshima H, Noda T, Takano Y: Postnatal development of periodontal Ruffini endings in rat incisors: an immunoelectron microscopic study using protein gene product 9.5 (PGP 9.5) antibody. J Comp Neurol 362: 551-564 (1995).
32. Ochi K, Saito I, Hanada K, Maeda T: Expression of TrkB-like immunoreactivity in non-neural cells of rat periodontal ligament. Arch Oral Biol 42: 455-464 (1997).
33. Ockel M, von Schack D, Schropel A, Dechant G, Lewin GR, Barde YA: Roles of neurotrophin-3 during early development of the peripheral nervous system. Philos Trans R Soc Lond B Biol Sci 351: 383-387 (1996a).
34. Ockel M, Lewin GR, Barde YA: In vivo effects of neurotrophin-3 during sensory neurogenesis. Development 122: 301-307 (1996b).
35. Sato O, Maeda T, Kobayashi S, Iwanaga T, Fujita T, Takahashi Y: Innervation of periodontal ligament and dental pulp in the rat incisor: An immunohistochemical investigation of neurofilament protein and glia-specific S-100 protein. Cell Tissue Res 251: 13-21 (1988).
36. Schroeder HE: Periodontal ligament. In: Handbook of microscopic anatomy. Vol. V/5, The periodoniutm. (Oksche A, Vollrath L, ed), Springer-Verlag, Berlin-Hederberg-New York, 1986 (p. 170-233).
37. Snider WD: Functions of the neurotrophins during nervous system development: what the knockouts are teaching us. Cell 77: 627-638 (1994).
38. Taylor A: Neurophysiology of the jaws and teeth. Macmilian Press, London 1990.
39. Thompson RJ, Doran JF, Jackson P, A. Dhillon P, Rode J: PGP 9.5 - a new marker for vertebrate neurons and neuroendocrine cells. Brain Res 278: 224-228 (1983).
40. Wakisaka S, Atsumi Y, Youn SH, Maeda T: Morphological and cytochemical characteristics of periodontal Ruffini ending under normal and regeneration processes. Arch Histol Cytol 63: 91-113 (2000).