메뉴 건너뛰기




Volumn 51, Issue 3, 2003, Pages 209-215

Growth suppression of a tumorigenic rat liver cell line by the anticancer agent, ET-18-O-CH3, is mediated by inhibition of cytokinesis

Author keywords

Anticancer, ras transformation; Cytokinesis; Tetraploidization

Indexed keywords

CYCLIN DEPENDENT KINASE 2; EDELFOSINE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE PHOSPHODIESTERASE; PROTEIN KINASE;

EID: 0037364871     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00280-003-0577-0     Document Type: Article
Times cited : (16)

References (36)
  • 1
    • 0032189615 scopus 로고    scopus 로고
    • Cytotoxic etherphospholipid analogues
    • Berkovic D (1998) Cytotoxic etherphospholipid analogues. Gen Pharmacol 31:511-517
    • (1998) Gen Pharmacol , vol.31 , pp. 511-517
    • Berkovic, D.1
  • 2
    • 0028143022 scopus 로고
    • Exposure to alkyllysophospholipids inhibits in vitro invasion of transitional cell carcinoma
    • Slaton JW, Hampton JA, Selman SH (1994) Exposure to alkyllysophospholipids inhibits in vitro invasion of transitional cell carcinoma. J Urol 152:1594-1598
    • (1994) J Urol , vol.152 , pp. 1594-1598
    • Slaton, J.W.1    Hampton, J.A.2    Selman, S.H.3
  • 3
    • 0031770976 scopus 로고    scopus 로고
    • The anticancer drug edelfosine is a potent inhibitor of neovascularization in vivo
    • Vogler WR, Liu J, Volpert O, Ades EW, Bouck N (1998) The anticancer drug edelfosine is a potent inhibitor of neovascularization in vivo. Cancer Invest 16:549-553
    • (1998) Cancer Invest , vol.16 , pp. 549-553
    • Vogler, W.R.1    Liu, J.2    Volpert, O.3    Ades, E.W.4    Bouck, N.5
  • 4
    • 0031892176 scopus 로고    scopus 로고
    • Apoptosis triggered by 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine is prevented by increased expression of CTP: Phosphocholine cytidylyltransferase
    • Baburina I, Jackowski S (1998) Apoptosis triggered by 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine is prevented by increased expression of CTP: phosphocholine cytidylyltransferase. J Biol Chem 273:2169-2173
    • (1998) J Biol Chem , vol.273 , pp. 2169-2173
    • Baburina, I.1    Jackowski, S.2
  • 6
    • 0032989980 scopus 로고    scopus 로고
    • Differential effects of free and liposome-associated 1-O-octadecyl-2-O-methylglycerophosphocholine on protein kinase C
    • Spiegel S, Olah Z, Cuvillier O, Edsall LC, Janoff AS (1999) Differential effects of free and liposome-associated 1-O-octadecyl-2-O-methylglycerophosphocholine on protein kinase C. FEBS Lett 454:137-141
    • (1999) FEBS Lett , vol.454 , pp. 137-141
    • Spiegel, S.1    Olah, Z.2    Cuvillier, O.3    Edsall, L.C.4    Janoff, A.S.5
  • 7
    • 0025740653 scopus 로고
    • Antineoplastic ether-linked phospholipid induces differentiation of acute myelogenous leukemic KG-1 cells into macrophage-like cells
    • Reed CB, Tang W, Ziboh VA (1991) Antineoplastic ether-linked phospholipid induces differentiation of acute myelogenous leukemic KG-1 cells into macrophage-like cells. Life Sci 49:1221-1227
    • (1991) Life Sci , vol.49 , pp. 1221-1227
    • Reed, C.B.1    Tang, W.2    Ziboh, V.A.3
  • 8
    • 0033491995 scopus 로고    scopus 로고
    • Inhibition of cell division but not nuclear division by 1-O-octadecyl-2-O-methyl-Sn-glycero-3-phosphocholine
    • Pushkareva MY, Janoff AS, Mayhew E (1999) Inhibition of cell division but not nuclear division by 1-O-octadecyl-2-O-methyl-Sn-glycero-3-phosphocholine. Cell Biol Int 23:817-828
    • (1999) Cell Biol Int , vol.23 , pp. 817-828
    • Pushkareva, M.Y.1    Janoff, A.S.2    Mayhew, E.3
  • 9
    • 0026663526 scopus 로고
    • Tumor cell kinetics following antineoplastic ether phospholipid treatment
    • Principe P, Sidoti C, Braquet P (1992) Tumor cell kinetics following antineoplastic ether phospholipid treatment. Cancer Res 52:2509-2515
    • (1992) Cancer Res , vol.52 , pp. 2509-2515
    • Principe, P.1    Sidoti, C.2    Braquet, P.3
  • 10
    • 1842290345 scopus 로고    scopus 로고
    • Selective induction of apoptosis in cancer cells by the ether lipid ET-18-OCH3 (edelfosine): Molecular structure requirements, cellular uptake, and protection by Bcl-2 and Bcl-X(L)
    • Mollinedo F, Fernandez-Luna JL, Gajate C, Martin-Martin B, Benito A, Martinez-Dalmau R, Modolell M (1997) Selective induction of apoptosis in cancer cells by the ether lipid ET-18-OCH3 (edelfosine): molecular structure requirements, cellular uptake, and protection by Bcl-2 and Bcl-X(L). Cancer Res 57:1320-1328
    • (1997) Cancer Res , vol.57 , pp. 1320-1328
    • Mollinedo, F.1    Fernandez-Luna, J.L.2    Gajate, C.3    Martin-Martin, B.4    Benito, A.5    Martinez-Dalmau, R.6    Modolell, M.7
  • 12
    • 0031968488 scopus 로고    scopus 로고
    • Involvement of c-Jun NH2-terminal kinase activation and c-Jun in the induction of apoptosis by the ether phospholipid 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine
    • Gajate C, Santos-Beneit A, Modolell M, Mollinedo F (1998) Involvement of c-Jun NH2-terminal kinase activation and c-Jun in the induction of apoptosis by the ether phospholipid 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine. Mol Pharmacol 53:602-612
    • (1998) Mol Pharmacol , vol.53 , pp. 602-612
    • Gajate, C.1    Santos-Beneit, A.2    Modolell, M.3    Mollinedo, F.4
  • 14
    • 0026742177 scopus 로고
    • Selective inhibition of phosphatidylinositol phospholipase C by cytotoxic ether lipid analogues
    • Powis G, Seewald MJ, Gratas C, Melder D, Riebow J, Modest EJ (1992) Selective inhibition of phosphatidylinositol phospholipase C by cytotoxic ether lipid analogues. Cancer Res 52:2835-2840
    • (1992) Cancer Res , vol.52 , pp. 2835-2840
    • Powis, G.1    Seewald, M.J.2    Gratas, C.3    Melder, D.4    Riebow, J.5    Modest, E.J.6
  • 15
    • 0034658432 scopus 로고    scopus 로고
    • Small cell lung carcinoma exhibits greater phospholipase C-betal expression and edelfosine resistance compared with non-small cell lung carcinoma
    • Strassheim D, Shafer SH, Phelps SH, Williams CL (2000) Small cell lung carcinoma exhibits greater phospholipase C-betal expression and edelfosine resistance compared with non-small cell lung carcinoma. Cancer Res 60:2730-2736
    • (2000) Cancer Res , vol.60 , pp. 2730-2736
    • Strassheim, D.1    Shafer, S.H.2    Phelps, S.H.3    Williams, C.L.4
  • 16
    • 0034465988 scopus 로고    scopus 로고
    • Modulation of the basal activity of phosphatidylinositol-3-kinase/protein kinase B signaling pathway in human hepatocarcinoma cells
    • Guo HB, Shen ZH, Huang CX, Ma J, Huang Y, Chen HL (2000) Modulation of the basal activity of phosphatidylinositol-3-kinase/protein kinase B signaling pathway in human hepatocarcinoma cells. Glycoconj J 17:315-322
    • (2000) Glycoconj J , vol.17 , pp. 315-322
    • Guo, H.B.1    Shen, Z.H.2    Huang, C.X.3    Ma, J.4    Huang, Y.5    Chen, H.L.6
  • 17
    • 0035937767 scopus 로고    scopus 로고
    • A critical role for phosphoinositide 3-kinase upstream of Gab1 and SHP2 in the activation of ras and mitogen-activated protein kinases by epidermal growth factor
    • Yart A, Laffargue M, Mayeux P, Chretien S, Peres C, Tonks N, Roche S, Payrastre B, Chap H, Raynal P (2001) A critical role for phosphoinositide 3-kinase upstream of Gab1 and SHP2 in the activation of ras and mitogen-activated protein kinases by epidermal growth factor. J Biol Chem 276:8856-8864
    • (2001) J Biol Chem , vol.276 , pp. 8856-8864
    • Yart, A.1    Laffargue, M.2    Mayeux, P.3    Chretien, S.4    Peres, C.5    Tonks, N.6    Roche, S.7    Payrastre, B.8    Chap, H.9    Raynal, P.10
  • 19
    • 0032746286 scopus 로고    scopus 로고
    • Ras-induced transformation and signaling pathway
    • Yamamoto T, Taya S, Kaibuchi K (1999) Ras-induced transformation and signaling pathway. J Biochem (Tokyo) 126:799-803
    • (1999) J Biochem (Tokyo) , vol.126 , pp. 799-803
    • Yamamoto, T.1    Taya, S.2    Kaibuchi, K.3
  • 20
    • 0025944173 scopus 로고
    • ras proteins and the ras-related signal transduction pathway
    • Janowski M (1991) ras proteins and the ras-related signal transduction pathway. Radiat Environ Biophys 30:185-189
    • (1991) Radiat Environ Biophys , vol.30 , pp. 185-189
    • Janowski, M.1
  • 22
    • 0029761702 scopus 로고    scopus 로고
    • Signal-transducing protein phosphorylation cascades mediated by Ras/Rho proteins in the mammalian cell: The potential for multiplex signalling
    • Denhardt DT (1996) Signal-transducing protein phosphorylation cascades mediated by Ras/Rho proteins in the mammalian cell: the potential for multiplex signalling. Biochem J 318:729-747
    • (1996) Biochem J , vol.318 , pp. 729-747
    • Denhardt, D.T.1
  • 25
    • 0022606121 scopus 로고
    • ras-transformed cells: Altered levels of phosphatidylinositol-4,5-bis-phosphate and catabolites
    • Fleischman LF, Chahwala SB, Cantley L (1986) ras-transformed cells: altered levels of phosphatidylinositol-4,5-bis-phosphate and catabolites. Science 231:407-410
    • (1986) Science , vol.231 , pp. 407-410
    • Fleischman, L.F.1    Chahwala, S.B.2    Cantley, L.3
  • 26
    • 0030942087 scopus 로고    scopus 로고
    • Increased concentrations of phosphatidate, diacylglycerol and ceramide in ras- and tyrosine kinase (fps)-transformed fibroblasts
    • Martin A, Duffy PA, Liossis C, Gomez MA, O'Brien L, Stone JC, Brindley DN (1997) Increased concentrations of phosphatidate, diacylglycerol and ceramide in ras- and tyrosine kinase (fps)-transformed fibroblasts. Oncogene 14:1571-1580
    • (1997) Oncogene , vol.14 , pp. 1571-1580
    • Martin, A.1    Duffy, P.A.2    Liossis, C.3    Gomez, M.A.4    O'Brien, L.5    Stone, J.C.6    Brindley, D.N.7
  • 27
    • 0033004404 scopus 로고    scopus 로고
    • Phosphatidylethanolamine and phosphatidylcholine are sources of diacylglycerol in ras-transformed NIH 3T3 fibroblasts
    • Momchilova A, Markovska T (1999) Phosphatidylethanolamine and phosphatidylcholine are sources of diacylglycerol in ras-transformed NIH 3T3 fibroblasts. Int J Biochem Cell Biol 31:311-318
    • (1999) Int J Biochem Cell Biol , vol.31 , pp. 311-318
    • Momchilova, A.1    Markovska, T.2
  • 29
    • 0035337097 scopus 로고    scopus 로고
    • Ras effectors: Buying shares in Ras plc
    • Cullen PJ (2001) Ras effectors: buying shares in Ras plc. Curr Biol 11:R342-R344
    • (2001) Curr Biol , vol.11
    • Cullen, P.J.1
  • 31
    • 0025323676 scopus 로고
    • Infection of rat liver epithelial cells with v-Ha-ras: Correlation between oncogene expression, gap junctional communication, and tumorigenicity
    • de-Feijter AW, Ray JS, Weghorst CM, Klaunig JE, Goodman JI, Chang CC, Ruch RJ, Trosko JE (1990) Infection of rat liver epithelial cells with v-Ha-ras: correlation between oncogene expression, gap junctional communication, and tumorigenicity. Mol Carcinog 3:54-67
    • (1990) Mol Carcinog , vol.3 , pp. 54-67
    • De-Feijter, A.W.1    Ray, J.S.2    Weghorst, C.M.3    Klaunig, J.E.4    Goodman, J.I.5    Chang, C.C.6    Ruch, R.J.7    Trosko, J.E.8
  • 32
    • 0029200154 scopus 로고
    • Quantification of apoptotic events in pure and heterogeneous populations of cells using the flow cytometer
    • Fraker PJ, King LE, Lill-Elghanian D, Telford WG (1995) Quantification of apoptotic events in pure and heterogeneous populations of cells using the flow cytometer. Methods Cell Biol 46:57-76
    • (1995) Methods Cell Biol , vol.46 , pp. 57-76
    • Fraker, P.J.1    King, L.E.2    Lill-Elghanian, D.3    Telford, W.G.4
  • 33
    • 0034739332 scopus 로고    scopus 로고
    • Restoration of gap junctional intercellular communication by caffeic acid phenylethyl ester (CAPE) in a ras-transformed rat liver epithelial cell line
    • Na HK, Wilson MR, Kang KS, Chang CC, Grunberger D, Trosko JE (2000) Restoration of gap junctional intercellular communication by caffeic acid phenylethyl ester (CAPE) in a ras-transformed rat liver epithelial cell line. Cancer Lett 157:31-38
    • (2000) Cancer Lett , vol.157 , pp. 31-38
    • Na, H.K.1    Wilson, M.R.2    Kang, K.S.3    Chang, C.C.4    Grunberger, D.5    Trosko, J.E.6
  • 35
    • 0030722721 scopus 로고    scopus 로고
    • A role for nuclear phosphatidylinositol-specific phospholipase C in the G2/M phase transition
    • Sun B, Murray NR, Fields AP (1997) A role for nuclear phosphatidylinositol-specific phospholipase C in the G2/M phase transition. J Biol Chem 272:26313-26317
    • (1997) J Biol Chem , vol.272 , pp. 26313-26317
    • Sun, B.1    Murray, N.R.2    Fields, A.P.3
  • 36
    • 0032491522 scopus 로고    scopus 로고
    • Nuclear diacylglycerol produced by phosphoinositide-specific phospholipase C is responsible for nuclear translocation of protein kinase C-alpha
    • Neri LM, Borgatti P, Capitani S, Martelli AM (1998) Nuclear diacylglycerol produced by phosphoinositide-specific phospholipase C is responsible for nuclear translocation of protein kinase C-alpha. J Biol Chem 273:29738-29744
    • (1998) J Biol Chem , vol.273 , pp. 29738-29744
    • Neri, L.M.1    Borgatti, P.2    Capitani, S.3    Martelli, A.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.