-
1
-
-
0034604110
-
Role of transforming growth factor beta in human disease
-
Blobe GC, Schiemann WP, Lodish HF. 2000. Role of transforming growth factor beta in human disease. N Engl J Med 342:1350-1358.
-
(2000)
N Engl J Med
, vol.342
, pp. 1350-1358
-
-
Blobe, G.C.1
Schiemann, W.P.2
Lodish, H.F.3
-
2
-
-
0028314271
-
The DCC gene: Structural analysis and mutations in colorectal carcinomas
-
Cho KR, Oliner JD, Simons JW, Hedrick L, Fearon ER, Preisinger AC, Hedge P, Silverman GA, Vogelstein B. 1994. The DCC gene: structural analysis and mutations in colorectal carcinomas. Genomics 19:525-531.
-
(1994)
Genomics
, vol.19
, pp. 525-531
-
-
Cho, K.R.1
Oliner, J.D.2
Simons, J.W.3
Hedrick, L.4
Fearon, E.R.5
Preisinger, A.C.6
Hedge, P.7
Silverman, G.A.8
Vogelstein, B.9
-
3
-
-
0030995125
-
Phenotype of mice lacking functional Deleted in colorectal cancer (Dcc) gene
-
Fazeli A, Dickinson SL, Hermiston ML, Tighe RV, Steen RG, Small CG, Stoeckli ET, Keino-Masu K, Masu M, Rayburn H, Simons J, Bronson RT, Gordon JI, Tessier-Lavigne M, Weinberg RA. 1997. Phenotype of mice lacking functional Deleted in colorectal cancer (Dcc) gene. Nature 386:796-804.
-
(1997)
Nature
, vol.386
, pp. 796-804
-
-
Fazeli, A.1
Dickinson, S.L.2
Hermiston, M.L.3
Tighe, R.V.4
Steen, R.G.5
Small, C.G.6
Stoeckli, E.T.7
Keino-Masu, K.8
Masu, M.9
Rayburn, H.10
Simons, J.11
Bronson, R.T.12
Gordon, J.I.13
Tessier-Lavigne, M.14
Weinberg, R.A.15
-
4
-
-
0025312728
-
A genetic model for colorectal tumorigenesis
-
Fearon ER, Vogelstein B. 1990. A genetic model for colorectal tumorigenesis. Cell 61:759-767.
-
(1990)
Cell
, vol.61
, pp. 759-767
-
-
Fearon, E.R.1
Vogelstein, B.2
-
5
-
-
0025056930
-
Identification of a chromosome 18q gene that is altered in colorectal cancers
-
Fearon ER, Cho KR, Nigro JM, Kern SE, Simons JW, Ruppert JM, Hamilton SR, Preisinger AC, Thomas G, Kinzler KW, Vogelstein B. 1990. Identification of a chromosome 18q gene that is altered in colorectal cancers. Science 247:49-56.
-
(1990)
Science
, vol.247
, pp. 49-56
-
-
Fearon, E.R.1
Cho, K.R.2
Nigro, J.M.3
Kern, S.E.4
Simons, J.W.5
Ruppert, J.M.6
Hamilton, S.R.7
Preisinger, A.C.8
Thomas, G.9
Kinzler, K.W.10
Vogelstein, B.11
-
6
-
-
0034902674
-
Disease model: Familial adenomatous polyposis
-
Fodde R, Smits R. 2001. Disease model: familial adenomatous polyposis. Trends Mol Med 7:369-373.
-
(2001)
Trends Mol Med
, vol.7
, pp. 369-373
-
-
Fodde, R.1
Smits, R.2
-
7
-
-
0035070046
-
Mutations in the APC tumour suppressor gene cause chromosomal instability
-
Fodde R, Kuipers J, Rosenberg C, Smits R, Kielman M, Gaspar C, van Es JH, Breukel C, Wiegant J, Giles RH, Clevers H. 2001. Mutations in the APC tumour suppressor gene cause chromosomal instability. Nat Cell Biol 3:433-438.
-
(2001)
Nat Cell Biol
, vol.3
, pp. 433-438
-
-
Fodde, R.1
Kuipers, J.2
Rosenberg, C.3
Smits, R.4
Kielman, M.5
Gaspar, C.6
Van Es, J.H.7
Breukel, C.8
Wiegant, J.9
Giles, R.H.10
Clevers, H.11
-
8
-
-
0032771825
-
Frequent 4-bp deletion in exon 9 of the SMAD4/MADH4 gene in familial juvenile polyposis patients
-
Friedl W, Kruse R, Uhlhaas S, Stolte M, Schartmann B, Keller KM, Jungck M, Stern M, Loff S, Back W, Propping P, Jenne DE. 1999. Frequent 4-bp deletion in exon 9 of the SMAD4/MADH4 gene in familial juvenile polyposis patients. Genes Chromosomes Cancer 25:403-406.
-
(1999)
Genes Chromosomes Cancer
, vol.25
, pp. 403-406
-
-
Friedl, W.1
Kruse, R.2
Uhlhaas, S.3
Stolte, M.4
Schartmann, B.5
Keller, K.M.6
Jungck, M.7
Stern, M.8
Loff, S.9
Back, W.10
Propping, P.11
Jenne, D.E.12
-
9
-
-
0032837376
-
Nonsense-mediated mRNA decay in health and disease
-
Frischmeyer PA, Dietz HC. 1999. Nonsense-mediated mRNA decay in health and disease. Hum Mol Genet 8:1893-1900.
-
(1999)
Hum Mol Genet
, vol.8
, pp. 1893-1900
-
-
Frischmeyer, P.A.1
Dietz, H.C.2
-
10
-
-
0028228920
-
The DCC gene product in cellular differentiation and colorectal tumorigenesis
-
Hedrick L, Cho KR, Fearon ER, Wu TC, Kinzler KW, Vogelstein B. 1994. The DCC gene product in cellular differentiation and colorectal tumorigenesis. Genes Dev 8:1174-1183.
-
(1994)
Genes Dev
, vol.8
, pp. 1174-1183
-
-
Hedrick, L.1
Cho, K.R.2
Fearon, E.R.3
Wu, T.C.4
Kinzler, K.W.5
Vogelstein, B.6
-
11
-
-
0035799597
-
A targeted mouse Brcal mutation removing the last BRCT repeat results in apoptosis and embryonic lethality at the headfold stage
-
Hohenstein P, Kielman MF, Breukel C, Bennett LM, Wiseman R, Krimpenfort P, Cornelisse C, van Ommen GJ, Devilee P, Fodde R. 2001. A targeted mouse Brcal mutation removing the last BRCT repeat results in apoptosis and embryonic lethality at the headfold stage. Oncogene 20:2544-2450.
-
(2001)
Oncogene
, vol.20
, pp. 2544-2450
-
-
Hohenstein, P.1
Kielman, M.F.2
Breukel, C.3
Bennett, L.M.4
Wiseman, R.5
Krimpenfort, P.6
Cornelisse, C.7
Van Ommen, G.J.8
Devilee, P.9
Fodde, R.10
-
12
-
-
0032524069
-
Mutations in the SMAD4/DPC4 gene in juvenile polyposis
-
Howe JR, Roth S, Ringold JC, Summers RW, Järvinen HJ, Sistonen P, Tomlinson APM, Houlston RS, Bevan S, Mitros FA, Stone EM, Aaltonen LA. 1998. Mutations in the SMAD4/DPC4 gene in juvenile polyposis. Science 280:1086-1088.
-
(1998)
Science
, vol.280
, pp. 1086-1088
-
-
Howe, J.R.1
Roth, S.2
Ringold, J.C.3
Summers, R.W.4
Järvinen, H.J.5
Sistonen, P.6
Tomlinson, A.P.M.7
Houlston, R.S.8
Bevan, S.9
Mitros, F.A.10
Stone, E.M.11
Aaltonen, L.A.12
-
13
-
-
0035092942
-
Serrated route to colorectal cancer: Back street or super highway?
-
Jass JR. 2001. Serrated route to colorectal cancer: back street or super highway? J Pathol 193:283-285.
-
(2001)
J Pathol
, vol.193
, pp. 283-285
-
-
Jass, J.R.1
-
14
-
-
0036227426
-
Evolution of colorectal cancer: Change of pace and change of direction
-
Jass JR, Young J, Leggett BA. 2002. Evolution of colorectal cancer: change of pace and change of direction. J Gastroenterol Hepatol 17:17-26.
-
(2002)
J Gastroenterol Hepatol
, vol.17
, pp. 17-26
-
-
Jass, J.R.1
Young, J.2
Leggett, B.A.3
-
15
-
-
0035090965
-
Colorectal carcinoma associated with serrated adenoma - Prevalence, histological features, and prognosis
-
Makinen MJ, George SM, Jernvall P, Makela J, Vihko P, Karttunen TJ. 2001. Colorectal carcinoma associated with serrated adenoma - prevalence, histological features, and prognosis. J Pathol 193:286-294.
-
(2001)
J Pathol
, vol.193
, pp. 286-294
-
-
Makinen, M.J.1
George, S.M.2
Jernvall, P.3
Makela, J.4
Vihko, P.5
Karttunen, T.J.6
-
16
-
-
0029066689
-
Inactivation of the type 11 TGF-beta receptor in colon cancer cells with microsatellite instability
-
Markowitz S, Wang J, Myeroff L, Parsons R, Sun L, Lutterbaugh J, Fan RS, Zborowska E, Kinzler KW, Vogelstein B, Brattain M, Wilson JKV. 1995. Inactivation of the type 11 TGF-beta receptor in colon cancer cells with microsatellite instability. Science 268: 1336-1338.
-
(1995)
Science
, vol.268
, pp. 1336-1338
-
-
Markowitz, S.1
Wang, J.2
Myeroff, L.3
Parsons, R.4
Sun, L.5
Lutterbaugh, J.6
Fan, R.S.7
Zborowska, E.8
Kinzler, K.W.9
Vogelstein, B.10
Brattain, M.11
Wilson, J.K.V.12
-
17
-
-
0005040712
-
Establishing new ES lines
-
Joyner AL, editor. Oxford: Oxford University Press
-
Matise MP, Auerbach W, Joyner AL. 2000. Establishing new ES lines. In: Joyner AL, editor. Gene targeting, a practical approach. Oxford: Oxford University Press, p. 129-131.
-
(2000)
Gene Targeting, a Practical Approach
, pp. 129-131
-
-
Matise, M.P.1
Auerbach, W.2
Joyner, A.L.3
-
18
-
-
0031595530
-
Assignmentl of the Smad7 gene (MADH7) to human chromosome 18q21.1 by fluorescence in situ hybridization
-
Röijer E, Moren A, ten Dijke P, Stenman G. 1998. Assignmentl of the Smad7 gene (MADH7) to human chromosome 18q21.1 by fluorescence in situ hybridization. Cytogenet Cell Genet 81:189-190.
-
(1998)
Cytogenet Cell Genet
, vol.81
, pp. 189-190
-
-
Röijer, E.1
Moren, A.2
Ten Dijke, P.3
Stenman, G.4
-
19
-
-
15444348295
-
The tumor suppressor gene Smad4/Dpc4 is required for gastrulation and later for anterior development of the mouse embryo
-
Sirard C, de la Pompa JL, Elia A, Itie A, Mirtsos C, Cheung A, Hahn S, Wakeham A, Schwartz L, Kern SE, Rossant J, Mak TW. 1998. The tumor suppressor gene Smad4/Dpc4 is required for gastrulation and later for anterior development of the mouse embryo. Genes Dev 12:107-119.
-
(1998)
Genes Dev
, vol.12
, pp. 107-119
-
-
Sirard, C.1
De la Pompa, J.L.2
Elia, A.3
Itie, A.4
Mirtsos, C.5
Cheung, A.6
Hahn, S.7
Wakeham, A.8
Schwartz, L.9
Kern, S.E.10
Rossant, J.11
Mak, T.W.12
-
20
-
-
0031408413
-
Loss of Apc and the entire chromosome 18 but absence of mutations at the Ras and Tp53 genes in intestinal tumors from Apc1638N, a mouse model for Apc-driven carcinogenesis
-
Smits R, Kartheuser A, Jagmohan-Changur S, Leblanc V, Breukel C, Vries Ad, Kranen Hv, Krieken JHv, Williamson S, Edelmann W, Kucherlapati R, Meera Khan P, Fodde R. 1997. Loss of Apc and the entire chromosome 18 but absence of mutations at the Ras and Tp53 genes in intestinal tumors from Apc1638N, a mouse model for Apc-driven carcinogenesis. Carcinogenesis 18:321-327.
-
(1997)
Carcinogenesis
, vol.18
, pp. 321-327
-
-
Smits, R.1
Kartheuser, A.2
Jagmohan-Changur, S.3
Leblanc, V.4
Breukel, C.5
Vries, A.D.6
Kranen, H.V.7
Krieken, J.H.V.8
Williamson, S.9
Edelmann, W.10
Kucherlapati, R.11
Meera Khan, P.12
Fodde, R.13
-
21
-
-
0033804719
-
Somatic Apc mutations are selected upon their capacity to inactivate the β-catenin downregulating activity
-
Smits R, Hofland N, Edelmann W, Geugien M, Jagmohan-Changur S, Albuquerque C, Breukel C, Kucherlapati R, Kielman MF, Fodde R. 2000. Somatic Apc mutations are selected upon their capacity to inactivate the β-catenin downregulating activity. Genes Chromosomes Cancer 29:229-239.
-
(2000)
Genes Chromosomes Cancer
, vol.29
, pp. 229-239
-
-
Smits, R.1
Hofland, N.2
Edelmann, W.3
Geugien, M.4
Jagmohan-Changur, S.5
Albuquerque, C.6
Breukel, C.7
Kucherlapati, R.8
Kielman, M.F.9
Fodde, R.10
-
22
-
-
0032489508
-
Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Apc genes
-
Takaku K, Oshima M, Miyoshi H, Matsui M, Seldin MF, Taketo MM. 1998. Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Apc genes. Cell 92:645-656.
-
(1998)
Cell
, vol.92
, pp. 645-656
-
-
Takaku, K.1
Oshima, M.2
Miyoshi, H.3
Matsui, M.4
Seldin, M.F.5
Taketo, M.M.6
-
23
-
-
0033572255
-
Gastric and duodenal polyps in Smad4 (Dpc4) knockout mice
-
Takaku K, Miyoshi H, Matsunaga A, Oshima M, Sasaki N, Taketo MM. 1999. Gastric and duodenal polyps in Smad4 (Dpc4) knockout mice. Cancer Res 59:6113-6117.
-
(1999)
Cancer Res
, vol.59
, pp. 6113-6117
-
-
Takaku, K.1
Miyoshi, H.2
Matsunaga, A.3
Oshima, M.4
Sasaki, N.5
Taketo, M.M.6
-
24
-
-
0034611611
-
Haploid loss of the tumor suppressor Smad4/Dpc4 initiates gastric polyposis and cancer in mice
-
Xu X, Brodie SG, Yang X, Im YH, Parks WT, Chen L, Zhou YX, Weinstein M, Kim SJ, Deng CX. 2000. Haploid loss of the tumor suppressor Smad4/Dpc4 initiates gastric polyposis and cancer in mice. Oncogene 19:1868-1874.
-
(2000)
Oncogene
, vol.19
, pp. 1868-1874
-
-
Xu, X.1
Brodie, S.G.2
Yang, X.3
Im, Y.H.4
Parks, W.T.5
Chen, L.6
Zhou, Y.X.7
Weinstein, M.8
Kim, S.J.9
Deng, C.X.10
-
25
-
-
0032584068
-
The tumor suppressor SMAD4/DPC4 is essential for epiblast proliferation and mesoderm induction in mice
-
Yang X, Li C, Xu X, Deng C. 1998. The tumor suppressor SMAD4/DPC4 is essential for epiblast proliferation and mesoderm induction in mice. Proc Natl Acad Sci USA 95:3667-3672.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 3667-3672
-
-
Yang, X.1
Li, C.2
Xu, X.3
Deng, C.4
|