Glyceraldehyde 3-phosphate dehydrogenase and endothelin-1 immunoreactivity is associated with cerebral white matter damage in dentatorubral-pallidoluysian atrophy

Neuropathology

Volumn 23, Issue 1, 2003, Pages 36-43

  Shiozawa, Masaki ^a,c,e   Fukutani, Yuken ^a   Arai, Nobutaka ^c   Cairns, Nigel J ^e   Mizutani, Toshio ^d   Isaki, Kiminori ^b   Lantos, Peter L ^e   Wada, Yuji ^a  

^a UNIVERSITY OF FUKUI   (Japan)

^b FUKUI PREFECTURAL UNIVERSITY   (Japan)

^c TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

^d TOKYO METROPOLITAN NEUROLOGICAL HOSPITAL   (Japan)

^e KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

CAG repeat; DRPLA; Endothelin 1; GAPDH

Indexed keywords

ENDOTHELIN 1; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; MESSENGER RNA; POLYSACCHARIDE; TISSUE PLASMINOGEN ACTIVATOR;

ARTICLE; ASTROCYTE; ASTROCYTOSIS; BRAIN INJURY; CENTRAL NERVOUS SYSTEM; CHROMOSOME 12P; DEGENERATIVE DISEASE; DENTATORUBROPALLIDOLUYSIAN ATROPHY; ENDOTHELIUM; ENZYME IMMOBILIZATION; GENOTYPE; GLYCOLYSIS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; PRIORITY JOURNAL; PROTEIN LOCALIZATION; REGULATORY MECHANISM; WHITE MATTER;

ADOLESCENT; ADULT; AGED; CHILD; CHROMOSOMES, HUMAN, PAIR 12; ENDOTHELIN-1; ENDOTHELIUM, VASCULAR; GENOTYPE; GLIAL FIBRILLARY ACIDIC PROTEIN; GLIOSIS; GLYCERALDEHYDE 3-PHOSPHATE; HUMANS; IMMUNOHISTOCHEMISTRY; MIDDLE AGED; MYOCLONIC EPILEPSIES, PROGRESSIVE; OLIGODENDROGLIA; TELENCEPHALON; TRINUCLEOTIDE REPEAT EXPANSION;

EID: 0037355372     PISSN: 09196544     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-1789.2003.00480.x     Document Type: Article

References (44)

1. Smith JK, Gonda VE, Malamud N. Unusual form of cerebellar ataxia: Combined dentate-rubral and pallido-Luysian degeneration. Neurology 1958; 13: 205-209.
2. Smith JK. Dentatorubropallidoluysian Atrophy. In: Vinken PJ, Bruyn GW (eds). Handbook of Clinical Neurology, Vol. 21. Amsterdam: North-Holland, 1975; 519-534.
3. Naito H, Oyanagi S. Familial myoclonus epilepsy and choreoathetosis: Hereditary dentatorubral-pallidoluysian atrophy. Neurology 1982; 32: 798-807.
4. Koide R, Ikeuchi T, Onodera O et al. Unstable expansion of CAG repeat in hereditary dentatorubral-pallidoluysian atrophy (DRPLA). Nat Genet 1994; 6: 9-13.
5. Nagafuchi S, Yanagisawa H, Sato K et al. Dentatorubral and pallidoluysian atrophy expansion of an unstable CAG trinucleotide on chromosome 12p. Nat Genet 1994; 6: 14-18.
6. Potter NT, Meyer MA, Zimmerman AW, Eisenstadt ML, Abderson IJ. Molecular and clinical findings in a family with dentatorubral-pallidoluysian atrophy. Ann Neurol 1995; 37: 273-277.
7. Ikeuchi T, Koide R, Tanaka H et al. Dentatorubral-pallidoluysian atrophy: Clinical features are closely related to unstable expansions of trinucleotide (CAG) repeat. Ann Neurol 1995; 37: 769-775.
8. Uyama E, Kodo I, Uchino M et al. Dentatorubral-pallidoluysian atrophy (DRPLA): Clinical, genetic, and neurologic studies in a family. J Neurol Sci 1995; 130: 146-153.
9. Miyashita K, Inuzuka T, Ishikawa A et al. Hereditary dentatorubropallidoluysian atrophy: Clinical variants in a family and degeneration of white matter in a proband. No Shinkei 1992; 44: 279-284 (in Japanese with English abstract).
10. Ihara Y, Namba R, Nobuyuki K, Kawai K, Kuroda S. Relation between cerebral white matter damage on CT and MRI and clinical data in DRPLA (pseudo-Huntington form). Rinsho Shinkeigaku 1991; 31: 815-820 (in Japanese with English abstract).
11. Arai K. White matter damage in dentatorubropallidoluysian atrophy: A radiological and neuropathological study. Neuropathology 1995; 15: 154-162.
12. Tokiguchi S, Naito H, Nagai H et al. CT findings of hereditary dentatorubral-pallidoluysian atrophy (DRPLA). CT Kenkyu 1987; 9: 665-672 (in Japanese with English abstract).
13. Shiozawa M, Fukutani Y, Isaki K, Hirayama M, Matsubara R. An autopsy case of dentatorubropallidoluysian atrophy: With reference to cerebral white matter lesions. Neurol Med 1999; 51: 165-170 (in Japanese with English abstract).
14. Takahashi H. Formation of neuronal inclusions and neurodegeneration: With special reference to dentatorubral-pallidoluysian atrophy. Rinsho Shinkeigaku 1999; 39: 1279-1281 (in Japanese with English abstract).
15. Yamada M, Piao YS, Toyoshima Y, Tsuji S, Takahashi H. Ubiquitinated filamentous inclusions in cerebellar dentate nucleus neurons in dentatorubral-pallidoluysian atrophy contain expanded polyglutamine stretches. Acta Neuropathol 2000; 99: 615-618.
16. Yamada M, Wood JD, Shimohata T et al. Widespread occurrence of intranuclear atrophin-1 accumulation in the central nervous system neurons of patients with dentatorubral-pallidoluysian atrophy. Ann Neurol 2001;49:14-23.
17. Yamada M, Tsuji S, Takahashi H. Pathology of CAG repeat diseases. Neuropathology 2000; 20: 319-325.
18. Ross CA, Becher MW, Colomer V, Engelender S, Wood JD. Huntington's disease and dentatorubral-pallidoluysian atrophy: Proteins, pathogenesis and pathology. Brain Pathol 1997; 7: 1003-1016.
19. Hayashi Y, Kakita A, Yamada M et al. Hereditary dentatorubral-pallidoluysian atrophy: Detection of widespread ubiquitinated neuronal and glial intranuclear inclusions in the brain. Acta Neuropathol 1998; 96: 547-552.
20. Burke JR, England JJ, Martin ME et al. Huntingtin and DRPLA proteins selectively interact with the enzyme GAPDH. Nat Med 1996; 2: 347-350.
21. Mayes PA. Glycolysis and oxidation of pyruvate. In: Murray RK, Granner DK, Mayes PA, Rodwell VW (eds). Harper's Biochemistry, 24th edn. Stamford: Appleton and Lange, 1996; 176-184.
22. Kooistra T, Toet K, Kluft C et al. Triazolobenzodiazepines: A new class of stimulators of tissue-type plasminogen activator synthesis in human endothelial cells. Biochem Phalmacol 1993; 46: 61-67.
23. Sjögren LS, Doroudi R, Gan LM, Jungersten L, Hrafnkelsdóttir T, Jern S. Elevated intraluminal pressure inhibits vascular tissue plasminogen activator secretion and downregulates its gene expression. Hypertension 2000; 35: 1002-1008.
24. Takahata N, Ito K, Yoshimura Y, Nishinori K, Suzuki H. Familial chorea and myoclonus epilepsy. Neurology 1978; 28: 913-919.
25. Nakano T, Iwabuchi K, Yagishita S, Amano N, Akagi M, Yamamoto Y. An autopsy case of dentatorubropallidoluysian atrophy (DRPLA) clinically diagnosed as Huntington's chorea. No Shinkei 1985; 37: 767-774 (in Japanese with English abstract).
26. Hotchkiss RD. A microchemical reaction resulting in the staining of polysaccharide structures in fixed tissue preparations. Arch Biochem 1948; 16: 131-141.
27. Iacono RF, Berria MI, Lascano EF. A triple procedure to evaluate phagocytotic role of differentiated astrocytes. J Neurosci Methods 1991; 39: 225-230.
28. Morisawa Y, Fujieda M, Murakami N et al. Lysosomal glycogen storage disease with normal acid maltase with early fatal outcome. J Neurol Sci 1998; 160: 175-179.
29. Jiang MH, Höög A, Ma KC, Nie JX, Olsson Y, Zhang WW. Endothelin-1-like immunoreactivity is expressed in human reactive astrocytes. Neuroreport 1993; 4: 935-937.
30. Zhang WW, Ma KC, Andersen O, Sourander P, Tollesson PO, Olsson Y. The microvascular changes in cases of hereditary multi-infarct disease of the brain. Acta Neuropathol 1994; 87: 317-324.
31. Tabernero A, Giaume C, Medina JM. Endothelin-1 regulates glucose utilization in cultured astrocytes by controlling intracellular communication through gap junctions. Glia 1996; 16: 187-195.
32. Sawaya R, Tofilon PJ, Mohanam S et al. Induction of tissue-type plasminogen activator and 72-kDa type IV collagenase by ionizing radiation in rat astrocytes. Int J Cancer 1994; 56: 214-218.
33. Tang H, Fu WY, Ip NY. Altered expression of tissue-type plasminogen activator and type 1 inhibitor in astrocytes of mouse cortex following scratch injury in culture. Neurosci Lett 2000; 285: 143-146.
34. Yoshii F, Tomiyasu H, Shinohara Y. Fluid attenuation inversion recovery (FLAIR) images of dentatorubro-pallidoluysian atrophy: Case report. J Neurol Neurosurg Psychiatry 1998; 65: 396-399.
35. Muñoz E, Milà A, Sánchez A et al. Dentatorubropal-lidoluysian atrophy in a Spanish family: Clinical radiological, pathological, and genetic study. J Neurol Neurosurg Psychiatry 1999; 67: 811-814.
36. n repeat number and age of onset in a family with dentatorubral-pallidoluysian atrophy (DRPLA): Diagnostic implications of confirmatory and predictive testing. J Med Genet 1996; 33: 168-170.
37. Becher MW, Rubistein DC, Leggo J et al. Dentatorubral and pallidoluysian atrophy (DRPLA): Clinical and neuropathological findings in genetically confirmed North American and European pedigrees. Mov Disord 1997; 12: 519-530.
38. Iwabuchi K, Amano N, Yokoi S, Nakano T, Yagishita S. Two familial cases of dentate-rubro-pallido-luysian atrophy with pseudo-Huntington's chorea. Clin Neurol 1985; 25: 1052-1060 (in Japanese with English abstract).
39. Hashida H, Goto J, Kurisaki H, Mizusawa H, Kanazawa I. Brain regional differences in the expansion of a CAG repeat in spinocerebellar ataxias: Dentatorubral-pallidoluysian atrophy, Machado-Joseph disease, and spinocerebellar ataxia type 1. Ann Neurol 1997; 41: 505-511.
40. Koide R, Onodera O, Ikeuchi T et al. Atrophy of cerebellum and brainstem in dentatorubral-pallidoluysian atrophy: Influence of CAG repeat size on MRI findings. Neurology 1997; 49: 1605-1612.
41. Takano H, Onodera O, Takahashi H et al. Somatic mosaicism of expanded CAG repeats in brains of patients with dentatorubral-pallidoluysian atrophy: Cellular population-dependent dynamics of mitotic instability. Am J Hum Genet 1996; 58: 1212-1222.
42. Ueno S, Kondoh K, Komure O et al. Somatic mosaicism of CAG repeat in dentatorubral-pallidoluysian atrophy (DRPLA). Hum Mol Genet 1995; 4: 663-666.
43. Filley CM. The behavioral neurology of cerebral white matter. Neurology 1998; 50: 1535-1540.
44. Rao SM. White matter disease and dementia. Brain Cogn 1996; 31: 250-268.