Bactericidal activity response of blood neutrophils from critically ill patients to in vitro granulocyte colony-stimulating factor stimulation

Intensive Care Medicine

Volumn 29, Issue 3, 2003, Pages 396-402

  Yang, Kun ^a   Azoulay, Élie ^a   Attalah, Lynda ^a   Zahar, Jean Ralph ^b   Van De Louw, Andry ^b   Cerf, Charles ^b   Soussy, Claude James ^b   Duvaldestin, Philippe ^b   Brochard, Laurent ^a,b   Brun Buisson, Christian ^b   Harf, Alain ^a,b   Delclaux, Christophe ^a,b  

^a FACULTÉ DE MÉDECINE   (France)

^b HENRI MONDOR HOSPITAL   (France)

Author keywords

Bactericidal activity; Critically ill patient; Granulocyte colony stimulating factor; Immunoparalysis; Neutrophil; Reactive oxygen species

Indexed keywords

GRANULOCYTE COLONY STIMULATING FACTOR; INTERLEUKIN 10; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ARTICLE; BACTERICIDAL ACTIVITY; CELL FUNCTION; CELL STIMULATION; CRITICAL ILLNESS; DISEASE SEVERITY; DOWN REGULATION; FEMALE; HOSPITAL INFECTION; HUMAN; IMMUNOREGULATION; IMMUNOSUPPRESSIVE TREATMENT; IN VITRO STUDY; MAJOR CLINICAL STUDY; MALE; NEUTROPHIL; PSEUDOMONAS AERUGINOSA; SCORING SYSTEM; STAPHYLOCOCCUS AUREUS;

EID: 0037348607     PISSN: 03424642     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00134-002-1623-9     Document Type: Article

References (33)

1. Root RK, DC Dale (1999) Granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor: comparisons and potential for use in the treatment of infections in nonneutropenic patients. J Infect Dis 179 [Suppl 2]:S342-S352
2. Nelson S, SM Belknap, RW Carlson, D Dale, B DeBoisblanc, S Farkas, N Fotheringham, H Ho, T Marrie, H Movahhed, R Root, J Wilson (1998) A randomized controlled trial of Filgrastim as an adjunct to antibiotics for treatment of hospitalized patients with community-acquired pneumonia. J Infect Dis 178:1075-1080
3. Esposito C, SM Banks, PQ Eichacker (1998) Prophylactic granulocyte colony-stimulating factor in critically ill patients: not time yet. Crit Care Med 26:636-637
4. Solberg CO, KB Hellum (1972) Neutrophil granulocyte function in bacterial infections. Lancet II:727-730
5. Simms HH, R D'Amico (1997) Post-traumatic auto-oxidative polymorphonuclear neutrophil receptor injury predicts the development of nosocomial infection. Arch Surg 132:171-177
6. Stephan F, K Yang, J Tankovic, CJ Soussy, G Dhonneur, P Duvaldestin, L Brochard, C Brun-Buisson, A Harf, C Delclaux (2002) Impairment of polymorphonuclear neutrophil functions precedes nosocomial infections in critically ill patients. Crit Care Med 30:315-322
7. Heard SO, MP Fink, RL Gamelli, JS Solomkin, M Joshi, AL Trask, TC Fabian, LD Hudson, KB Gerold, ED Logan (1998) Effect of prophylactic administration of recombinant human granulocyte colony-stimulating factor (filgrastim) on the frequency of nosocomial infections in patients with acute traumatic brain injury or cerebral hemorrhage. Crit Care Med 26:748-754
8. Pettila V, O Takkunen, T Varpula, A Markkola, K Porkka, V Valtonen (2000) Safety of granulocyte colony-stimulating factor (filgrastim) in intubated patients in the intensive care unit: interim analysis of a prospective, placebo-controlled, double-blind study. Crit Care Med 28:3620-3655
9. Richards MJ, JR Edwards, DH Culver, RP Gaynes (1999) Nosocomial infections in medical intensive care units in the United States. National Nosocomial Infections Surveillance System. Crit Care Med 27:887-892
10. Quie PG, JG White, G Holmes, RA Good (1967) in vitro bactericidal capacity of human polymorphonuclear leukocytes: diminished activity in chronic granulomatous disease of childhood. J Clin Invest 46:668
11. Mizgerd JP, JD Brain (1995) Reactive oxygen species in the killing of Pseudomonas aeruginosa by human leukocytes. Curr Microbiol 31:124-128
12. Le Gall JR, S Lemeshow, F Saulnier (1993) A new simplified acute physiology score (SAPS II) based on a European/North American multicenter study. JAMA 270:2957-2963
13. Vincent JL, R Moreno, J Takala, S Willatts, A De Mendonca, H Bruining, CK Reinhart, PM Suter, LG Thijs (1996) The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure. On behalf of the Working Group on Sepsis-Related Problems of the European Society of Intensive Care Medicine. Intensive Care Med 22:707-710
14. Gross-Weege W, K Dumon, A Dahmen, EM Schneider, HD Röher (1997) Granulocyte colony-stimulating factor (G-CSF) serum levels in surgical intensive care patients. Infection 25:213-216
15. Faulkner LB, F Tucci, A Tamburini, V Tintori, AA Lippi, F Bambi, F Malentacca, C Azzari, AMG Gelli, F Genovese, G Bernini (1998) G-CSF serum pharmacokinetics during peripheral blood progenitor cell mobilization: neutrophil count-adjusted dosage might potentially improve mobilization and be more cost-effective. Bone Marrow Transplant 21:1091-1095
16. Döcke WD, F Randow, U Syrbe, D Krausch, K Asadullah, P Reinke, HD Volk, W Kox (1997) Monocyte deactivation in septic patients: restauration by INF-γ treatment. Nat Med 3:678-681
17. Munford RS, J Pugin (2001) Normal responses to injury prevent systemic inflammation and can be immunosuppressive. Am J Respir Crit Care Med 163:316-321
18. Lejeune M, A Ferster, B Cantinieaux, E Sariban (1998) Prolonged but reversible neutrophil dysfunctions differentially sensitive to granulocyte colony-stimulating factor in children with acute lymphoblastic leukaemia. Br J Haematol 102:1284-1291
19. Roilides E, TJ Walsh, PA Pizzo, M Rubin (1991) Granulocyte colony-stimulating factor enhances the phagocytic and bactericidal activity of normal and defective human neutrophils. J Infect Dis 163:579-583
20. Lejeune M, E Sariban, B Cantinieaux, A Ferster, C Devalck, P Fondu (1996) Defective polymorphonuclear leukocyte functions in children receiving chemotherapy for cancer are partially restored by recombinant human granulocyte colony-stimulating factor in vitro. J Infect Dis 174:800-805
21. Anding K, A Kropec, E Schmidt-Eisenlohr, A Benzing, K Geiger, F Daschner (1993) Enhancement of in vitro bactericidal activity of neutrophils from trauma patients in the presence of granulocyte colony-stimulating factor. Eur J Clin Microbiol Infect Dis 12:121-124
22. Ishikawa K, H Tanaka, T Matsuoka, T Shimazu, T Yoshioka, H Sugimoto (1998) Recombinant human granulocyte colony-stimulating factor attenuates inflammatory responses in septic patients with neutropenia. J Trauma 44:1047-1054-
23. Hollenstein U, M Homoncik, PJ Stohlawetz, C Marsik, A Sieder, HG Eichler, B Jilma (2000) Endotoxin down-modulates granulocyte colony-stimulating factor receptor (CD114) on human neutrophils. J Infect Dis 182:343-346
24. Jilma B, N Hergovich, M Homoncik, P Jilma-Stohlawetz, C Kreuzer, HG Eichler, M Zellner, J Pugin (2000) Granulocyte colony-stimulating factor (G-CSF) downregulates its receptor (CD114) on neutrophils and induces gelatinase B release in humans. Br J Haematol 111:314-320
25. Weiss M, EM Schneider, J Tarnow, S Mettler, M Krone, A Teschemacher, H Lemoine (1996) Is inhibition of oxygen radical production of neutrophils by sympathomimetics mediated via beta-2 adrenoceptors? J Pharmacol Exp Ther 278:1105-1113
26. Olas B, B Wachowicz, A Buczynski (2000) The effects of granulocyte colony stimulating factor on chemiluminescence and lipid peroxidation of blood platelets treated with cisplatin. Anticancer Drugs 11:79-84
27. Cassatella MA (1998) The neutrophil: one of the cellular targets of interleukin-10. Int J Clin Lab Res 28:148-161
28. Giannoudis PV, RM Smith, SL Perry, AJ Windsor, RA Dickson, MC Bellamy (2000) Immediate IL-10 expression following major orthopaedic trauma: relationship to anti-inflammatory response and subsequent development of sepsis. Intensive Care Med 26:1076-1081
29. Boneberg EM, L Hareng, F Gantner, A Wendel, T Hartung (2000) Human monocytes express functional receptors for granulocyte colony-stimulating factor that mediate suppression of monokines and interferon-gamma. Blood 95:270-276
30. Karzai W, BU von Specht, C Parent, J Haberstroh, K Wollersen, C Natanson, SM Banks, PQ Eichacker (1999) G-CSF during Escherichia coli versus Staphylococcus aureus pneumonia in rats has fundamentally different and opposite effects. Am J Respir Crit Care Med 159:1377-1382
31. Vincent JL, DJ Bihari, PM Suter, HA Bruining, J White, MH Nicolas-Chanoin, M Wolff, RC Spencer, M Hemmer (1995) The prevalence of nosocomial infection in intensive care units in Europe. Results of the European Prevalence of Infection in Intensive Care (EPIC) Study. EPIC International Advisory Committee. JAMA 274:639-644
32. Girou E, M Pinsard, I Auriant, M Canonne (1996) Influence of the severity of illness measured by the Simplified Acute Physiology Score (SAPS) on occurrence of nosocomial infections in ICU patients. J Hosp Infect 34:131-137
33. Attalah HL, E Azoulay, C Lasclos, H Jouault, CJ Soussy, T Guillot, L Brochard, C Brun-Buisson, A Harf, C Delclaux (2002) Granulocyte colony-stimulating factor enhances host defenses against lung bacterial superinfection following peritonitis in non-neutropenic rats. Crit Care Med 30:2107-2114