Matrix Gla protein gene expression and protein accumulation colocalize with cartilage distribution during development of the teleost fish Sparus aurata

Bone

Volumn 32, Issue 3, 2003, Pages 201-210

  Pinto, J P ^a   Conceicao N ^a   Gavaia, P J ^a   Cancela, M L ^a  

^a UNIVERSITY OF ALGARVE   (Portugal)

Author keywords

Bone and cartilage appearance; Development; Matrix Gla protein; Osteocalcin; Sparus aurata

Indexed keywords

BIOLOGICAL MARKER; MATRIX GLA PROTEIN; MESSENGER RNA; OSTEOCALCIN; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; BONE MINERALIZATION; CARTILAGE; CARTILAGINOUS TISSUE; CONTROLLED STUDY; DEVELOPMENTAL STAGE; EXTRACELLULAR MATRIX; GENE AMPLIFICATION; GENE CONTROL; GENE EXPRESSION; GENE LOCATION; HEART; HEART MUSCLE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; JAW; KIDNEY; NONHUMAN; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; OSTEOBLAST; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ANALYSIS; SKULL; SOUTHERN BLOTTING; TELEOST;

SPARUS AURATA;

EID: 0037347260     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/S8756-3282(02)00981-X     Document Type: Article

References (28)

1. Price P.A., Williamson M.K. Primary structure of bovine Matrix Gla protein, a new vitamin K-dependent bone protein. J Biol Chem. 260:1985;14971-14975.
2. Price P.A., Urist M.R., Otawara Y. Matrix Gla protein, a new gamma-carboxyglutamic acid-containing protein which is associated with the organic matrix of bone. Biochem Biophys Res Commun. 117:1983;765-771.
3. Luo G., Ducy P., McKee M.D., Pinero G.J., Loyer E., Behringer R.R., Karsenty G. Spontaneous calcification of arteries and cartilage in mice lacking matrix Gla protein. Nature. 386:1997;78-81.
4. Price P.A., Faus S.A., Williamson M.K. Warfarin-induced artery calcification is accelerated by growth and vitamin D. Arterioscler Thromb Vasc Biol. 20:2000;317-327.
5. Price P.A., Faus S.A., Williamson M.K. Warfarin causes rapid calcification of the elastic lamellae in rat arteries and heart valves. Arterioscler Thromb Vasc Biol. 18:1998;1400-1407.
6. Hale J.E., Fraser J.D., Price P.A. The identification of matrix Gla protein in cartilage. J Biol Chem. 263:1988;5820-5824.
7. Shanahan C.M., Proudfoot D., Farzaneh-Far A., Weissberg P.L. The role of Gla proteins in vascular calcification. Crit Rev Eukaryot Gene Express. 8:1998;357-375.
8. Shanahan C.M., Cary N.R.B., Salisbury J.R., Proudfoot D., Weissberg P.L., Edmonds M. Medial localization of mineralization-regulating proteins in association with Monckeberg's Sclerosis; evidence for smooth cell-mediated vascular calcification. Circulation. 100:1999;2168-2176.
9. Simes D.C., Williamson M.K., Ortiz-Delgado J.B., Viegas C.S., Price P.A., Cancela M.L. Purification of matrix G1a protein from a marine teleost fish, Argyrosomus regius: calcified cartilage and not bone as the primary site of MGP accumulation in fish. J Bone Miner Res. 18:2003;244-259.
10. Fraser J.D., Price P.A. Lung, heart and kidney express high levels of mRNA for the vitamin K-dependent matrix Gla protein. J Biol Chem. 263:1988;11033-11036.
11. Cancela M.L., Ohresser M.C., Reia J.P., Viegas C.S., Williamson M.K., Price P.A. Matrix Gla Protein in Xenopus laevis- molecular cloning, tissue distribution and evolutionary considerations. J Bone Miner Res. 16:2001;1611-1621.
12. Shanahan C.M., Cary N.R.B., Metcalfe J.C., Weissberg P. High expression of genes for calcification-regulating proteins in human atherosclerotic plaques. J Clin Invest. 93:1994;2393-2402.
13. Conceição N., Henriques N.M., Ohresser M.C., Hublitz P., Schule R., Cancela M.L. Molecular cloning of the Matrix Gla Protein gene from Xenopus laevis. Functional analysis of the promoter identifies a calcium sensitive region required for basal activity. Eur J Biochem. 269:2002;1947-1956.
14. Laizé V., Pombinho A.R., Cancela M.L. Development of bone-derived cell lines from a marine teleost: establishment of the first in vitro model system from fish suitable to analyse regulatory pathways of Matrix G1a protein and osteocalcin gene expression. J Bone Miner Res. 17(Suppl 1):2002;S406.
15. Chomczynski P., Sacchi N. Single step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Analyt Biochem. 162:1987;156-159.
16. Sanger F., Donelson J.E., Coulson A.R., Kossel H., Fischer D. Use of DNA polymerase I primed by a synthetic oligonucleotide to determine a nucleotide sequence in phage fl DNA. Proc Natl Acad Sci USA. 70:1973;1209-1213.
17. Sambrook J., Fritsch E.F., Maniatis T. Molecular cloning A laboratory manual . 2nd ed :1989;Laboratory Press, Cold Spring Harbor, NY. 7.46.
18. Pinto J.P., Ohresser M., Cancela M.L. Cloning of the Bone Gla Protein Gene from the teleost fish Sparus aurata. Evidence for overall conservation in molecular structure and pattern of expression from fish to man. Gene. 270:2001;77-91.
19. Jee W.S.S. The skeletal tissues. Weiss L. Cell and tissue biology. 1988;211-254 Urban & Schwarzenberg, Munich.
20. Yagami K., Suh J.-Y., Enomoto-Iwamoto M., Koyama E., Abrams W.R., Shapiro I.M., Pacifici M., Iwamoto M. Matrix Gla protein is a developmental regulator of chondrocyte mineralization and, when constitutively expressed, blocks endochondral and intramembranous ossification in the limb. J Cell Biol. 147:1999;1097-1108.
21. Ikeda T., Nomura S., Yamaguchi A., Suda T., Yoshiki S. In situ hybridization of bone matrix proteins in undecalcified adult rat bone sections. J Histochem Cytochem. 40:1992;1079-1088.
22. Price P.A., Otsuka A.S., Poser J.W., Kristaponis J., Raman N. Characterization of a γ-carboxyglutamic acid-containing protein from bone. Proc Natl Acad Sci USA. 73:1976;1447-1451.
23. Witten P.E., Villwock W. Growth requires bone resorption at particular skeletal elements in a teleost fish with acellular bone (Oreochromis niloticus, Teleostei Cichlidae) . J Appl Ichthyol. 13:1997;149-158.
24. Bostrom K., Tsao D., Shen S., Wang Y., Demer L.L. Matrix Gla protein modulates differentiation induced by bone morphogenetic protein-2 in C3H10T1/2 cells. J Biol Chem. 276:2001;14044-14052.
25. Alagao F.C., Patel R., Price P.A. Matrix Gla protein specifically inhibits calcification of human aortic elastin in vitro. J Bone Miner Res. 15:(Suppl 1):2000;S208.
26. Howe A.M., Webster W.S. Warfarin exposure and calcification of the arterial system in the rat. Int J Exp Path. 81:2000;51-56.
27. Wallin R., Cain D., Sane D.C. Matrix Gla protein synthesis and gamma-carboxylation in the aortic vessel wall and proliferating vascular smooth muscle cells. Thromb Haemost. 82:1999;1764-1767.
28. Luo G., Dsouza R., Hougue D., Karsenty G. The matrix Gla protein is a marker of the chondrogenesis cell lineage during mouse development. J Bone Miner Res. 10:1995;325-334.