Effects of acamprosate on excitatory amino acids during multiple ethanol withdrawal periods

Alcoholism: Clinical and Experimental Research

Volumn 27, Issue 3, 2003, Pages 465-470

  Dahchour, Abdelkader ^a   De Witte, Philippe ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

Author keywords

Acamprosate; Excitatory Amino Acids; Microdialysis; Repeated Ethanol Withdrawal

Indexed keywords

ACAMPROSATE; ALCOHOL; ASPARTIC ACID; EXCITATORY AMINO ACID; GLUTAMIC ACID;

ALCOHOL WITHDRAWAL; ALCOHOLISM; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ELECTROCHEMICAL DETECTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INHALATION; LONG TERM CARE; MALE; MICRODIALYSIS; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; VAPOR;

ANIMALS; ETHANOL; EXCITATORY AMINO ACIDS; HIPPOCAMPUS; MALE; RATS; RATS, WISTAR; SUBSTANCE WITHDRAWAL SYNDROME; TAURINE;

ANIMALIA; RATTUS NORVEGICUS;

EID: 0037345627     PISSN: 01456008     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.ALC.0000056617.68874.18     Document Type: Article

References (35)

1. al Qatari M, Bouchenafa O, Littleton J (1998) Mechanism of action of acamprosate. Part II: Ethanol dependence modifies effects of acamprosate on NMDA receptor binding in membranes from rat cerebral cortex. Alcohol Clin Exp Res 22:810-814.
2. al Qatari M, Khan S, Harris B, Littleton J (2001) Acamprosate is neuroprotective against glutamate-induced excitotoxicity when enhanced by ethanol withdrawal in neocortical cultures of fetal rat brain. Alcohol Clin Exp Res 25:1276-1283.
3. 2+ channels in cultured rat mesencephalic neurones. Naunyn Schmiedebergs Arch Pharmacol 362:440-443.
4. Becker HC, Diaz-Granados JL, Hale RL (1997) Repeated ethanol withdrawal increase the severity and duration of subsequent withdrawal seizures in mice. Alcohol 14:319-326.
5. Becker HC, Hale RL (1993) Repeated episodes of ethanol withdrawal potentiate the severity of subsequent withdrawal seizures: an animal model of alcohol withdrawal "kindling." Alcohol Clin Exp Res 17:1994-1998.
6. Boismare F, Daoust M, Moore N, Saligaut C, Lhuintre JP, Chretien P, Durlach J (1984) A homotaurine derivative reduces the voluntary intake of ethanol by rats: are cerebral GABA receptors involved? Pharmacol Biochem Behav 21:787-789.
7. Bolo N, Nedelec JF, Muzet M, De Witte P, Dahchour A, Durbin P, Macher JP (1998) Central effects of acamprosate: Part 2. Acamprosate modifies the brain in-vivo proton magnetic resonance spectrum in healthy young male volunteers. Psychiatry Res Neuroimaging 82:115-127.
8. Dahchour A, De Witte P (1999) Acamprosate decrease the hypermotility during repeated ethanol withdrawal. Alcohol 18:77-81.
9. Dahchour A, De Witte P, Bolo N, Nédélec JF, Durbin P, Macher JP (1998) Central effect of acamprosate: Part 1. Acamprosate blocks the glutamate increase in the nucleus accumbens microdialysate during ethanol withdrawn rats. Psychiatry Res Neuroimaging 82:107-114.
10. Donzanti BA, Yamamoto BK (1988) An improved and rapid HPLC-EC method for the isocratic separation of amino acids neurotransmitters from brain tissue and microdialysis perfusates. Life Sci 43:913-922.
11. Douglas RM (1967) The hippocampus and behaviour. Psychol Bull 67:416-442.
12. French ED, Vezzani A, Shetseel WO, Schwarcz R (1986) Anti-excitotoxic actions of taurine in the rat hippocampus studied in vivo and in vitro. Adv Exp Med Biol 203:349-362.
13. Gewiss M, Heidbreder C, Opsomer L, Durbin P, De Witte P (1991) Acamprosate and diazepam differentially modulate alcohol-induced behavioural and cortical alterations in rats following chronic inhalation of ethanol vapour. Alcohol Alcohol 26:129-137.
14. Gray JA (1982) The Neuropsychology of Anxiety. Oxford University Press, Oxford, UK.
15. Heyser CJ, Schulteis G, Durbin P, Koob GF (1998) Chronic acamprosate eliminates the alcohol deprivation effect while having limited effects on baseline responding for ethanol in rats. Neuropsychopharmacology 18:125-133.
16. Holter SM, Landgraf R, Zieglgänsberger W, Spanagel R (1997) Time course of acamprosate action on operant ethanol self-administration after ethanol deprivation. Alcohol Clin Exp Res 21:862-868.
17. Kontro P, Oja SS (1988) Release of taurine, GABA and dopamine from rat striatal slices: mutual interactions and developmental aspects. Neuroscience 24:49-58.
18. Kratzer U, Schmidt WJ (1998) The anti-craving drug acamprosate inhibits the conditioned place aversion induced by naloxone-precipitated morphine withdrawal in rats. Neurosci Lett 252:53-56.
19. Le Bourhis B (1975) Alcoolisation du rat par voie pulmonaire. Comptes rendus des séances de la Société de Biologie 169:898-904.
20. Le Magnen J, Tran G, Durlach J, Martin C (1987) Dose-dependent suppression of the high alcohol intake of chronically intoxicated rats by calcium acetyl homotaurinate. Alcohol 4:97-102.
21. McCown TJ, Breese GR (1990) Multiple withdrawals from chronic ethanol "kindles" inferior collicular seizure activity: evidence for kindling of seizures associated with alcoholism. Alcohol Clin Exp Res 14:394-399.
22. Naassila M, Hammoumi S, Legrand E, Durbin P, Daoust M (1998) Mechanism. of action of acamprosate. Part I. Characterization of spermidine-sensitive acamprosate binding site in rat brain. Alcohol Clin Exp Res 22:802-809.
23. Oja SS, Korpi ER, Saransaari P (1990) Modification of chloride flux across brain membranes by inhibitory amino acids in developing and adult mice. Neurochem Res 15:797-804.
24. Paille FM, Guelfi JD, Perkins AC, Royer RJ, Steru L, Parot P (1995) Double-blind randomized multicentre trial of acamprosate in maintaining abstinence from alcohol. Alcohol Alcohol 30:239-247.
25. Paxinos G, Watson C (1982) The Rat Brain, in Stereotaxic Coordinates. Academic Press, New York.
26. Poldrugo F, Snead OC (1984) Electroencephalographic and behavioral correlates in rats during repeated ethanol withdrawal syndromes. Psychopharmacology Berl 83:140-146.
27. Popp RL, Lovinger DM (2000) Interaction of acamprosate with ethanol and spermine on NMDA receptors in primary cultured neurons. Eur J Pharmacol 394:221-231.
28. Putzke J, Spanagel R, Tolle TR, Zieglgänsberger W (1996) The anticraving drug acamprosate reduces c-fos expression in rats undergoing ethanol withdrawal. Eur J Pharmacol 317:39-48.
29. Rammes G, Mahal B, Putzke J, Parsons C, Spielmanns P, Pestel E, Spanagel R, Zieglgänsberger W, Schadrack J (2001) The anti-craving compound acamprosate acts as a weak NMDA-receptor antagonist, but modulates NMDA-receptor subunit expression similar to memantine and MK-801. Neuropharmacology 40:749-760.
30. Sass H, Soyka M, Mann K, Zieglgänsberger W (1996) Relapse prevention by acamprosate: results from a placebo-controlled study on alcohol dependence. Arch Gen Psychiatry 53:673-680.
31. Spanagel R, Holter SM, Allingham K, Landgraf R, Zieglgänsberger W (1996) Acamprosate and alcohol: I. Effects on alcohol intake following alcohol deprivation in the rat. Eur J Pharmacol 305:39-44.
32. Spanagel R, Zieglgänsberger W (1997) Anti-craving compounds for ethanol: new pharmacological tools to study addictive processes. Trends Pharmacol Sci 18:54-59.
33. Traub RD, Miles R (1991) Neuronal Networks of the Hippocampus. Cambridge University Press, Cambridge, UK.
34. Trenkner E (1990) The role of taurine and glutamate during early postnatal cerebellar development of normal and weaver mutant mice. Adv Exp Med Biol 268:239-244.
35. Veatch LM, Gonzalez P (1996) Repeated ethanol withdrawal produces site-dependent increases in EEG spiking. Alcohol Clin Exp Res 20:262-267.