Infection of rats with Taenia taeniformis metacestodes increases hepatic CYP450, induces the activity of CYP1A1, CYP2B1 and COH isoforms and increases the genotoxicity of the procarcinogens benzo[a]pyrene, cyclophosphamide and aflatoxin B1

Mutagenesis

Volumn 18, Issue 2, 2003, Pages 211-216

  Montero, Regina ^c   Serrano, Luis ^c   Dávila, Víctor M ^c   Ito, Akira ^b   Plancarte, Agustín ^a  

^a UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^b Asahikawa University   (Japan)

^c UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

Author keywords

[No Author keywords available]

Indexed keywords

AFLATOXIN B1; BENZO[A]PYRENE; COUMARIN HYDROXYLASE; CYCLOPHOSPHAMIDE; CYTOCHROME P450 1A1; CYTOCHROME P450 2B1; CYTOCHROME P450 2E1; ISOENZYME; LIVER ENZYME; OXYGENASE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CANCER SUSCEPTIBILITY; CESTODE; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; GENOTOXICITY; LIVER METABOLISM; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; TAENIA TAENIAEFORMIS; TAENIASIS;

AFLATOXIN B1; ANIMALS; ARYL HYDROCARBON HYDROXYLASES; BENZO(A)PYRENE; CARCINOGENS; CATS; CYCLOPHOSPHAMIDE; CYTOCHROME P-450 CYP1A1; CYTOCHROME P-450 CYP2B1; FEMALE; IMMUNOBLOTTING; LIVER; MICROSOMES, LIVER; MIXED FUNCTION OXYGENASES; MUTAGENS; NITROPHENOLS; PROTEIN ISOFORMS; RATS; RATS, SPRAGUE-DAWLEY; RETICULOCYTES; TAENIA; TIME FACTORS;

ANIMALIA; CESTODA; TAENIA; TAENIA TAENIAEFORMIS;

EID: 0037340876     PISSN: 02678357     EISSN: None     Source Type: Journal    
DOI: 10.1093/mutage/18.2.211     Document Type: Article

References (39)

1. Anwar,W. and Rosin,M. (1993) Reduction in chromosomal damage in schistosomiasis patients after treatment with Praziquantel. Mutat. Res., 298, 179-185.
2. Béréziat,J.C., Raffalli,F., Schmezer,P., Frei,E., Genste,O. and Lang,M.A. (1995) Cytochrome P450 2A of nasal epithelium: regulation and role in carcinogen metabolism. Mol. Carcinog., 14, 130-139.
3. Bethizy,J.D. and Hayes,J.R. (1994) Metabolism. A determinant of toxicity. In Hayes,A.W. (ed.), Principles and Methods of Toxicology, 3rd Edn. Raven Press, New York, NY, pp. 59-97.
4. Bradford,M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem., 72, 248-254.
5. Brandes,L.J., Queen,G.M. and LaBella,F.S. (1998) Potent interaction of histamine and polyamines at microsomal cytochrome P450, nuclei, and chromatin from rat hepatocyes. J. Cell Biochem., 69, 233-243.
6. Burke,M.D., Thompson,S., Weavwer,R.J., Wolf,C.R. and Mayer,R.T. (1994) Cytochrome P450 specificities of alkoxyresorufin O-dealkylation in human and rat liver. Biochem. Pharmacol., 48, 923-936.
7. Camus-Randon,A.M., Raftalli,F., Béréziat,J.C., McGregor,D., Konstandi,M. and Lang,M. (1996) Liver injury and expression of cytochromes P450: evidence that regulation of CYP2A5 is different from that of other major xenobiotic metabolizing CYP enzymes. Toxicol. Appl. Pharmacol., 138, 140-148.
8. Del Bruto,O., Castillo,P., Mena,I. and Freire,A. (1997) Neurocysticercosis among patients with cerebral gliomas. Arch. Neurol., 54, 1125-1128.
9. Delescluse,C., Lemaire,G., de Sousa,G. and Rahmani,R. (2000) Is CYP1A1 induction always related to AHR signaling pathway? Toxicology, 153, 73-82.
10. Ding,S., Yao,D., Burchell,B., Wolf,C.R. and Friedberg,T. (1997) High levels of recombinant CYP3A4 expression in Chinese hamster ovary cells are modulated by coexpressed human P450 reductase and hemin supplementation. Arch. Biochem. Biophys., 348, 403-410.
11. Ding,S., Yao,D., Deeni,Y.Y., Burchell,B., Wolf,C.R. and Friedberg,T. (2001) Human NADPH-P450 oxidoreductase modulates the level of cytochrome P450 CYP2D6 holoprotein via haem oxygenase-dependent and -independent pathways. Biochem. J., 356, 613-619.
12. Eaton,D. and Gallagher,E. (1994) Mechanisms of aflatoxin carcinogenesis. Annu. Rev. Pharmacol. Toxicol., 34, 135-172.
13. Flisser,A., González,D., Plancarte,A., Ostrosky,P., Montero,R., Stephano,A. and Correa,D. (1990) Praziquantel treatment of brain and muscle porcine Taenia solium cisticercosis. Parasitol. Res., 76, 640-642.
14. 1 metabolism in human liver. Proc. Natl Acad. Sci. USA, 87, 8306-8310.
15. Gentile,J.M. and De Ruiter,E. (1981) Promutagen activation in parasite-infected organisms: preliminary observations with Fasciola hepatica-infected mice and aflatoxin B1. Toxicol. Lett., 8, 273-282.
16. Herrera,L.A., Santiago,P., Rojas,G., Salazar,P.M., Tato,P., Molinari,J.L., Schiffmann,D. and Ostrosky,P. (1994) Immune response impairment, genotoxicity and morphological transformation induced by Taenia solium metacestode. Mutat. Res., 305, 223-228.
17. Herrera,L.A., Ramírez,T., Rodríguez,U., Corona,T., Sotelo,J., Lorenzo,M., Ramos,F., Verdorfer,I., Gebhart,E. and Ostrosky,P. (2000) Posible association between Taenia solium cisticercosis and cancer: increased frequency of DNA damage in peripheral lymphocytes from neurocysticercosis patients. Trans. R. Soc. Trop. Med. Hyg., 94, 61-65.
18. Herrera,L.A., Rodriguez,U., Gebhart,E. and Ostrosky-Wegman,P. (2001) Increased translocation frequency of chromosomes 7, 11 and 14 in lymphocytes from patients with neurocysticercosis. Mutagenesis, 16, 495-497.
19. Kirby,G.M., Pelkonen,P., Vatanasapt,V., Camus,A.M., Wild,C.P. and Lang,M. (1994a) Association of liver fluke (Opisthorchis viverrini) infestation with increased expression of cytochrome P450 and carcinogen metabolism in male hamster liver. Mol. Carcinog., 11, 81-89.
20. Kirby,G.M., Chemin,Y., Montesano,R., Chisari,F.V., Lang,M.A. and Wild,C.P. (1994b) Induction of specific cytochrome P450s involved in aflatoxin B1 metabolism in hepatitis B virus transgenic mice. Mol. Carcinog., 11, 74-80.
21. Koop,D.R. (1986) Hydroxylation of p-nitrophenol by rabbit ethanol-inducible cytochrome P-450 isozyme 3a. Mol. Pharmacol., 29, 399-404.
22. Laemmli,U.K. (1970) Maturation of the head of bacteriophage T4 I DNA packaging events. Nature, 227, 280.
23. LaBella,F.S. and Brandes,L.J. (2000) Interaction of histamine and other bioamines with cytochromes P450: implications for cell growth modulation and chemopotentiation by drugs. Semin. Cancer Biol., 10, 47-53.
24. Lewis,D. (2001) Substrate selectivity and metabolism. In Guide to Cytochromes P450. Structure and Function, Ch. 4. Taylor and Francis, London, UK.
25. Maron,D. and Ames,B. (1983) Revised methods for the Salmonella mutagenicity test. Mutat. Res., 113, 173-215.
26. Montero,R. and Ostrosky,P. (1997) Genotoxic activity of Praziquantel. Mutat. Res., 387, 123-139.
27. Montero,R., Flisser,A., Madrazo,I., Cuevas,C. and Ostrosky,P. (1994) Mutation at the HPRT locus in patients with neurocysticercosis treated with praziquantel. Mutat. Res., 305, 181-188.
28. Montero,R., Gentile,G.J., Frederick,L., McMannis,J., Murphy,T., Silva,G., Blankespoor,H. and Gentile,J.M. (1999) Induced expression of CYP2A5 in inflamed trematode-infested mouse liver. Mutagenesis, 14, 217-220.
29. Morgan,E.T. (1997) Regulation of cytochromes P450 during inflammation and infection. Drug Metab. Rev., 29, 1129-1188.
30. Motorna,O.O., Martin,H., Gentile,G.J. and Gentile,J.M. (2001) Analysis of lacI mutations in Big Blue® transgenic mice subjected to parasite-induced inflammation. Mutat. Res., 484, 69-76.
31. Omura,T. and Sato,R. (1964) The carbon monoxide-binding pigment of liver microsomes. J. Biol. Chem., 239, 2370-2378.
32. Pearce,R., Greenway,D. and Parkinson,A. (1992) Species differences and interindividual variation in liver microsomal cytochrome P450 2A enzymes: effects on coumarin, dicumarol, and testosterone oxidation. Arch. Biochem. Biophys., 298, 211-225.
33. Rautio,A., Kraul,H., Kojo,A., Salmela,E. and Pelkonen,O. (1992) Inter-individual variability of coumarin 7-hydroxylation in healthy volunteers. Pharmacogenetics, 2, 227-233.
34. Ribeiro,L.F., Moraes,E., Albano,R.M., Silva,M.C., Godoy,W., Glisovic,T. and Lang,M.A. (2001) Rat oesophageal cytochrome P450 (CYP) monooxygenase system: comparison to the liver and relevance in N-nitro-sodiethylamine carciongenesis. Carcinogenesis, 22, 1877-1883.
35. Romagna,F. and Staniforth,C.D. (1989) The automated bone marrow micronucleus test. Mutat. Res., 213, 91-104.
36. Ross,R., Yuan,J.M., Yu,M., Wogan,G., Qian,G.S., Tu,J.T., Groopman,J.D., Gao,Y.T. and Henderson,B.E. (1992) Urinary aflatoxin biomarkers and risk of hepatocellular carcinoma. Lancet, 339, 943-946.
37. Serrano,L. and Montero,R. (2001) Micronuclei and chromatin buds are the result of related genotoxic events. Environ. Mol. Mutagen., 38, 38-45.
38. Towbin,H., Staehelin,T. and Gordon,J. (1979) Electrophoretic transfer of protein from polyacrylamide gels to nitrocellulose-sheets: procedure and same applications. Proc. Natl Acad. Sci. USA, 76, 4350-4354.
39. Vandewaa,E.A., Barney,C.C. and Gentile,J.M. (1982) Promutagen activation in partially hepatectomized mice. Toxicol. Lett., 14, 253-260.