Fine-needle aspiration cytology and immunocytochemistry in the diagnosis of 24 gastrointestinal stromal tumors: A quick, reliable diagnostic method

Diagnostic Cytopathology

Volumn 28, Issue 3, 2003, Pages 131-135

  Lozano, Maria D ^a   Rodriguez, J ^a   Algarra, Salvador Martín ^a   Panizo, Angel ^a   Sola, Jesús J ^a   Pardo, Javier ^a  

^a UNIVERSITY CLINIC OF NAVARRA   (Spain)

Author keywords

Aspiration cytology; C kit; FNA; Gastrointestinal stromal tumors; Immunocytochemistry

Indexed keywords

CD34 ANTIGEN; STEM CELL FACTOR;

ADULT; AGED; ARTICLE; ASPIRATION BIOPSY; CLINICAL ARTICLE; COMPUTER ASSISTED TOMOGRAPHY; CYTOPATHOLOGY; DIAGNOSTIC ACCURACY; ECHOGRAPHY; FEMALE; GASTROINTESTINAL TUMOR; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOCYTOCHEMISTRY; MALE; PAPANICOLAOU TEST; PATHOLOGICAL ANATOMY; PRIORITY JOURNAL; RELIABILITY; STROMA;

ADULT; AGED; AGED, 80 AND OVER; ANTIGENS, CD34; BIOPSY, NEEDLE; FEMALE; GASTROINTESTINAL NEOPLASMS; HUMANS; IMMUNOENZYME TECHNIQUES; MALE; MESENCHYMOMA; MIDDLE AGED; PROTO-ONCOGENE PROTEINS C-KIT; STROMAL CELLS; TUMOR MARKERS, BIOLOGICAL;

EID: 0037337711     PISSN: 87551039     EISSN: None     Source Type: Journal    
DOI: 10.1002/dc.10260     Document Type: Article

References (26)

1. Miettinen M, Sarlomo-Rikala M, Lasota J. Gastrointestinal stromal tumors: recent advances understanding of their biology. Hum Pathol 1999;30:1213-1220.
2. Sircar K, Hewlett BR, Huizinga JD, Chorneyco K, Berezin I, Riddell RH. Interstitial cells of Cajal as a precursors of gastrointestinal stromal tumors. Am J Surg Pathol 1999;23:377-389.
3. Sarlomo-Rikala M, Kovatich AJ, Barusevicius A, Miettinen M. CD117: a sensitive marker for gastrointestinal stromal tumors that is more specific than CD34. Mod Pathol 1998;11:728-734.
4. Miettinen M, Lasota J. Gastrointestinal stromal tumors: definition, clinical, histological, immunohistochemical, and molecular genetic features and differential diagnosis. Virchows Arch 2001;438:1-12.
5. Miettinen M, Sobin LH, Sarlomo-Rikala M. Immunohistochemical spectrum of GISTs at different sites and their differential diagnosis with a reference to CD117(KIT). Mod Pathol 2000;13:1134-1142.
6. Lasota J, Jasinski M, Sarlomo-Rikala M, Miettinen M. Mutations in exon 11 of c-Kit occur preferentially in malignant versus benign gastrointestinal stromal tumors and do not occur in leiomyomas or leiomyosarcomas. Am J Pathol 1999;154:53-60.
7. Li SQ, O'Leary T, Sobin LH, Erozan YS, Rosenthal DL, Przygodzki RM. Analysis of KIT mutation and protein expression in fine needle aspirates of gastrointestinal stromal/smooth muscle tumors. Acta Cytol 2000;44:981-986.
8. Rader AE, Avery A, Wait CL, McGreevey LS, Faigel D, Heinrich MC. Fine-needle aspitarion biopsy diagnosis of gastrointestinal stromal tumors using morphology, immunocytochemistry, and mutational analysis of c-kit. Cancer Cytopathol 2001;93:269-275.
9. Wardelmann E, Neidt I, Bierhoff E, Speidel N, Manegold C, Fischer HP, Pfeifer U, Pietsch T. C-kit mutations in gastrointestinal stromal tumors occur preferentially in the spindle rather than in the epithelioid cell variant. Mod Pathol 2002;15:125-136.
10. Corless CL, McGreevey L, Haley A, Town A, Heinrich MC. KIT mutations are common in incidental gastrointestinal stromal tumors one centimeter or less in size. Am J Pathol 2002;160:1567-1572.
11. Joensu H, Roberts PJ, Sarlomo-Rikala M, Andersson LC, Tervahartiala P, Tuveson D, Silberman SL, Capdeville R, Dimitrijevic S, Druker B, Demetri GD. Effect of the tyrosine kinase inhibitor STI571 in a patient with metastatic gastrointestinal stromal tumor. N Engl J Med 2001;344:1052-1056.
12. Blanke CD, Eisenberg BL, Heinrich MC. Gastrointestinal stromal tumors. Curr Treat Opin Oncol 2001;2:485-491.
13. Heinrich MC, Blanke CD, Corless CL. Inhibition of KIT tyrosine kinase activity: a novel molecular approach to the treatment of KIT-positive malignancies. J Clin Oncol 2002;20:1692-1703.
14. Emory TS, Sobin LH, Lukes L, Lee DH, O'Leary TJ. Prognosis of gastrointestinal smooth-muscle (stroma) tumors: dependence of anatomic site. Am J Surg Pathol 1999;23:82-87.
15. Panizo-Santos A, Sola I, Vega F, De Alava E, Lozano MD, Idoate MA, Pardo-Mindán J. Predicting metastatic risk of gastrointestinal stromal tumors: role of cell proliferation and cell cycle regulatory proteins. Int J Surg Pathol 2000;8:133-144.
16. Seidal T, Edvardsson H. Diagnosis of gastrointestinal stromal tumor by fine needle aspiration biopsy: a cytological and immunocytochemical study. Diagn Cytopathol 2000;23:397-401.
17. Gu M, Ghafari S, Nguyen PT, Lin F. Cytologic diagnosis of gastrointestinal stromal tumors of the stomach by endoscopic ultrasound-guided fine-needle aspiration biopsy: cytomorphologic and immunohistochemical study of 12 cases. Diagn Cytopathol 2001;25:343-350.
18. Lozano MD, Panizo A, Toledo GR, Sola JJ, Pardo-Mindán J. Immunocytochemistry in the differential diagnosis of serous effusions: a comparative evaluation using eight monoclonal antibodies in Papanicolau stained smears. Cancer Cytopathol 2001;93:68-72.
19. Li SQ, O'Leary TJ, Buchner SB, Przygodzki RM, Sobin LH, Erozan YS, Rosenthal DL. Fine needle aspiration of gastrointestinal stromal tumors. Acta Cytol 2001;45:9-17.
20. Boggino HE, Fernandez MP, Logroño R. Cytomorphology of gartrointestinal stroma tumor: diagnostic role of aspiration cytology, core biopsy, and immunochemistry. Diagn Cytopathol 2000;23:156-160.
21. Kwon MS, Koh JS, Lee SS, Chung JH, Ahn GH. Fine needle aspiration cytology (FNAC) of gastrointestinal stromal tumor: an emphasis on diagnostic role of FNAC, cell block, and immunohistochemistry. J Korean Med Sci 2002;17:353-359.
22. Erozan YS. Endoscopic ultrasound-guided fine-needle aspiration. Acta Cytol 1997;41:1645-1646.
23. Ando N, Goto H, Niwa Y, Hirooka Y, Ohmiya N, Nagasaka T, Hayakawa T. The diagnosis of GI stromal tumors with EUS-guided fine needle aspiration with immunohistochemical analysis. Gastrointest Endosc 2002;55:37-43.
24. Dodd LG, Nelson RC, Mooney EE, Gottfried M. Fine needle aspiration of gastrointestinal stromal tumors. Am J Clin Pathol 1998;109: 439-443.
25. Cheuk W, Lee KC, Chan JKC. C-kit Immunocytochemical staining in the cytologic diagnosis of metastatic gastrointestinal stromal tumor: a report of two cases. Acta Cytol 2000;44:679-685.
26. Wieczorek TJ, Faquin WC, Rubin BP, Cibas ES. Cytologic diagnosis of gastrointestinal stromal tumor with emphasis on the differential diagnosis with leiomyosarcoma. Cancer Cytopathol 2001;93:276-287.