Placental immunomodulator ferritin, a novel immunoregulator, suppresses experimental arthritis

Arthritis and Rheumatism

Volumn 48, Issue 3, 2003, Pages 846-853

  Weinberger, Abraham ^a,b   Halpern, Marisa ^a,b   Zahalka, Muayad A ^a,b   Quintana, Francisco ^c   Traub, Leonid ^a,b   Moroz, Chaya ^a,b  

^a RABIN MEDICAL CENTER   (Israel)

^b TEL AVIV UNIVERSITY   (Israel)

^c WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

C 48; FERRITIN; IMMUNOMODULATING AGENT; INTERLEUKIN 10; INTERLEUKIN 2; PLACENTAL IMMUNOMODULATOR FERRITIN; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; ZYMOSAN;

ADJUVANT ARTHRITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTHRITIS; ARTICLE; BONE EROSION; CARTILAGE DEGENERATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EFFECT; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HISTIOCYTE; HISTOPATHOLOGY; IMMUNOMODULATION; IMMUNOREGULATION; IN VITRO STUDY; MIXED LYMPHOCYTE REACTION; MONONUCLEAR CELL; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE DIAGNOSIS; SPLEEN CELL; SYNOVIUM; TH2 CELL; TUBERCULOUS ARTHRITIS;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ARTHRITIS, EXPERIMENTAL; CARRIER PROTEINS; CELLS, CULTURED; CYTOKINES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FERRITINS; HINDLIMB; INJECTIONS, INTRAPERITONEAL; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; JOINTS; LYMPHOCYTES; MICE; MICE, INBRED C57BL; MICE, INBRED ICR; NERVE TISSUE PROTEINS; PREGNANCY PROTEINS; RATS; RATS, INBRED LEW; SPLEEN; ZYMOSAN;

EID: 0037334623     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/art.10850     Document Type: Article

References (36)

1. Smith WD, West HF. Pregnancy in rheumatoid arthritis. Scand J Rheumatol 1960;6:189-201.
2. Felbo M, Snorrason E. Pregnancy and the place of therapeutic abortion in rheumatoid arthritis. Acta Obstet Gynecol Scand 1961;40:116-26.
3. Neely NT, Persellin RH. Activity of rheumatoid arthritis during pregnancy. Tex Med 1977;73:59-63.
4. Ostensen M, Aune B, Husby G. Effect of pregnancy and hormonal changes on the activity of rheumatoid arthritis. Scand J Rheumatol 1983;12:69-72.
5. Østensen M, Husby G. A prospective clinical study of the effect of pregnancy on rheumatoid arthritis and ankylosing spondylitis. Arthritis Rheum 1983;26:1155-9.
6. Unger A, Kay A, Griffin AJ, Panayi GS. Disease activity and pregnancy associated alpha 2-glycoprotein in rheumatoid arthritis during pregnancy. Br Med J (Clin Res Ed) 1983;286:750-2.
7. Barrett JH, Brennan P, Fiddler M, Silman AJ. Does rheumatoid arthritis remit during pregnancy and relapse postpartum? Results from a nationwide study in the United Kingdom performed prospectively from late pregnancy. Arthritis Rheum 1999;42:1219-27.
8. Vorgensen C, Sany J. Modulation of the immune response by the neuroendocrine axis in rheumatoid arthritis. Clin Exp Rheumatol 1994;12:435-41.
9. Mattsson R, Mattsson A, Holmdahl R, Whyte A, Rook GA. Maintained pregnancy levels of oestrogen afford complete protection from postpartum exacerbation of collagen-induced arthritis. Clin Exp Immunol 1991;85:41-7.
10. Jara LJ, Lavalle C, Fraga A, Gomez-Sanchez C, Silviera LH, Martinez-Osuna P, et al. Prolactin, immunoregulation and autoimmune diseases. Semin Arthritis Rheum 1991;20:273-84.
11. Rook GA, Steele J, Brenley R, Whyte A, Isenberg D, Sumar N, et al. Changes in IgG glycoform levels are associated with remission of arthritis during pregnancy. J Autoimmun 1991;4:779-94.
12. Bond A, Ratkay LG, Warterfield JD, Hay FC. Postpartum flare in MRL-lpr/lpr mice is associated with a parallel increase of N-acetylglucosamine on serum IgG. Br J Rheumatol 1997;36:174-7.
13. Sirota L, Kupfer B, Moroz C. Placental isoferritin as a physiological down regulator of cellular immunoreactivity during pregnancy. Clin Exp Immunol 1989;77:257-62.
14. Maymon R, Jauniaux E, Greenwold N, Moroz C. Localization of p43 placental isoferritin in human feto-maternal tissue interface. Am J Obstet Gynecol 2000;182:670-4.
15. Maymon R, Moroz C. Placental isoferritin: a new biomarker from conception to delivery. Br J Obstet Gynaecol 1996;103:301-5.
16. Moroz C, Traub L, Maymon R, Zahalka MA. PLIF: a novel human ferritin subunit from placenta with immunosuppressive activity. J Biol Chem 2002;277:12901-5.
17. Keystone EC, Schorlemmer HU, Pope C, Allison AC. Zymosan-induced arthritis: a model of chronic proliferative arthritis following activation of the alternative pathway of complement. Arthritis Rheum 1977;20:1396-401.
18. Pearson CM. Development of arthritis periarthritis periostitis in rats given adjuvants. Proc Soc Exp Biol Med 1956;91:95-101.
19. Coligon JE, Kruisbeek AM, Margulies DH, Shevach EM, Strober W. Adjuvant arthritis in the rat. In: Coligon JE, Kruisbeek AM, Margulies DH, Shevach EM, Strober W, editors. Current Protocols in Immunology. Suppl 19. New York: John Wiley & Sons; 1996. p. 15.4.1-7.
20. Quintana FJ, Rotem A, Carmi P, Cohen IR. Vaccination with empty plasmid DNA or CpG oligonucleotide inhibits diabetes in nonobese diabetic mice: modulation of spontaneous 60-kDa heat shock protein autoimmunity. J Immunol 2000;165:6148-55.
21. Dingle JT, Page Thomas DP, Hazleman B. The role of cytokines in arthritic diseases: in vitro and in vivo measurements of cartilage degradation. Int J Tissue React 1987;9:349-54.
22. Von Asmuth EJ, Maessen JG, van der Linden CJ, Buurman WA. Tumor necrosis factor alpha (TNF-α) and interleukin 6 in a zymosan-induced shock model. Scand J Immunol 1990;32:313-9.
23. Erdo F, Torok K, Szekely JI. Measurement of interleukin-1 liberation in zymosan air-pouch exudate in mice. Agents Actions 1994;41:93-5.
24. Deleuran BW, Chu CQ, Field M, Brennan FM, Katsiki P, Feldmann M, et al. Localization of interleukin-1α, type 1 interleukin-1 receptor and interleukin-1 receptor antagonist in the synovial membrane and cartilage/pannus junction in rheumatoid arthritis. Br J Rheumatol 1992;31:801-9.
25. Farahat MN, Yanni G, Poston R, Panayi GS. Cytokine expression in synovial membranes of patients with rheumatoid arthritis and osteoarthritis. Ann Rheum Dis 1993;52:870-5.
26. Van Roon JAG, van Roy JLAM, Gmelig-Meyling FHJ, Lafeber FPJG, Bijlsma JWJ. Prevention and reversal of cartilage degradation in rheumatoid arthritis by interleukin-10 and interleukin-4. Arthritis Rheum 1996;39:829-35.
27. Joosten LAB, Lubberts E, Durez P, Helsen MMA, Jacobs MJM, Goldman M, et al. Role of interleukin-4 and interleukin-10 in murine collagen-induced arthritis: protective effect of interleukin-4 and interleukin-10 treatment on cartilage destruction. Arthritis Rheum 1997;40:249-60.
28. Verhoef CM, van Roon JAG, Vianen ME, Bruinzeel-Koomen CAFM, Lafeber FPJG, Bijlsma JWJ. Mutual antagonism of rheumatoid arthritis and hayfever: a role for type I and type 2 T cell balance. Ann Rheum Dis 1998;57:275-80.
29. Zahalka MA, Barak V, Traub L, Moroz C. The bioactive domain of PLIF is a direct inducer of IL-10 production in monocytes: a calcium/calmodulin p38 MAP kinase dependent pathway. FASEB J. In press.
30. Maymon R, Bahary C, Moroz C. Placental isoferritin measured by a specific monoclonal antibody as a predictive marker for preterm contraction outcome. Obstet Gynecol 1989;74:1-3.
31. Wegmann TG, Lin H, Guilbert L, Mosmann TR. Bidirectional cytokine interactions in the maternal-fetal relationship: is successful pregnancy a TH2 phenomenon? Immunol Today 1993;14:353-6.
32. Abramsky O. Pregnancy and multiple sclerosis. Ann Neurol 1994;36:S38-S41.
33. Confavreux C, Hutchinson M, Hours MM, Cortinovis-Tourniaire P, Moreau T, the Pregnancy in Multiple Sclerosis Group. Rate of pregnancy-related relapse in multiple sclerosis. N Engl J Med 1998;339:285-91.
34. Elenkov I, Wilder R, Bakalov V, Link A, Dimitrov M, Fisher S, et al. IL-12, TNF-alpha, and hormonal changes during late pregnancy and early postpartum: implications for autoimmune disease activity during these times. J Clin Endocrinol Metab 2001;86:4933-8.
35. Rosen AC, Hafner E, Auerbach L, Rosen HR, Schuchter K, Huber K, et al. Placental isoferritin in pregnancies with small-for-gestational age fetuses. Prenat Diagn 1996;16:641-6.
36. Bowden A, Barrett J, Fallow W, Silma A. Women with inflammatory polyarthritis have babies of lower birth weight. J Rheumatol 2001;28:355-9.