Post-ischemic administeration but not pre-ischemic administeration of NG-nitro-L-arginine prevents spatial memory impairments and apoptosis by an inhibition of a delayed increase in NOx- in the hippocampus following repeated cerebral ischemia

Neuropharmacology

Volumn 44, Issue 4, 2003, Pages 533-540

  Mishima, K ^a   Pu, F ^a   Kaneko, T ^a   Egashira, N ^a   Iwasaki, K ^a   Fujiwara, M ^a  

^a FUKUOKA UNIVERSITY   (Japan)

Author keywords

Eight arm radial maze; L NAME; Microdialysis; NO; Repeated ischemia; Spatial memory

Indexed keywords

N(G) NITROARGININE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; NITROGEN DIOXIDE; ENZYME INHIBITOR; NITRIC OXIDE SYNTHASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BLOOD LEVEL; BRAIN ISCHEMIA; CONTROLLED STUDY; DRUG MECHANISM; HIPPOCAMPUS; MALE; MAZE TEST; MEMORY DISORDER; MORTALITY; NICK END LABELING; NONHUMAN; OCCLUSION; PRIORITY JOURNAL; RAT; REPERFUSION; SPATIAL MEMORY; SURVIVAL RATE; ANIMAL; DISEASE MODEL; DRUG ANTAGONISM; DRUG EFFECT; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; INTRAPERITONEAL DRUG ADMINISTRATION; MEMORY; METABOLISM; MICRODIALYSIS; PATHOLOGY; PSYCHOLOGICAL ASPECT; TIME; VASCULARIZATION; WISTAR RAT;

ANIMALS; APOPTOSIS; BRAIN ISCHEMIA; DISEASE MODELS, ANIMAL; ENZYME INHIBITORS; HIPPOCAMPUS; INJECTIONS, INTRAPERITONEAL; INJECTIONS, INTRAVENTRICULAR; MAZE LEARNING; MEMORY; MICRODIALYSIS; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITROARGININE; RATS; RATS, WISTAR; TIME FACTORS;

EID: 0037333842     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(02)00404-5     Document Type: Article

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