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Volumn 136, Issue 1-2, 2003, Pages 25-33

IL-1β-dependent neurological effects of the whole cell pertussis vaccine: A role for IL-1-associated signalling components in vaccine reactogenicity

Author keywords

Hypothalamus; IL 1 receptors; IL 1ra; IL 1 ; Pertussis vaccines; Stress activated kinases

Indexed keywords

ACELLULAR VACCINE; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; INTERLEUKIN 2 RECEPTOR; MESSENGER RNA; PERTUSSIS VACCINE; STRESS ACTIVATED PROTEIN KINASE; DIPHTHERIA PERTUSSIS TETANUS VACCINE; IL1RN PROTEIN, MOUSE; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR TYPE I; INTERLEUKIN 1 RECEPTOR TYPE II; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; SIALOGLYCOPROTEIN;

EID: 0037333723     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-5728(02)00468-X     Document Type: Article
Times cited : (16)

References (58)
  • 1
    • 0036681655 scopus 로고    scopus 로고
    • Native and genetically inactivated pertussis toxins induce human dendritic cell maturation and synergize with lipopolysaccharide in promoting T helper type 1 responses
    • Ausiello C.M., Fedele G., Urbani F., Lande R., Di Carlo B., Cassone A. Native and genetically inactivated pertussis toxins induce human dendritic cell maturation and synergize with lipopolysaccharide in promoting T helper type 1 responses. J. Infect. Dis. 186:2002;351-360.
    • (2002) J. Infect. Dis. , vol.186 , pp. 351-360
    • Ausiello, C.M.1    Fedele, G.2    Urbani, F.3    Lande, R.4    Di Carlo, B.5    Cassone, A.6
  • 3
    • 0034731649 scopus 로고    scopus 로고
    • Differential gene regulation of interleukin-1 ligands and receptors in bovine peripheral blood neutrophils and mononuclear cells in response to E. coli lipopolysaccharide (LPS)
    • Beckman M.J., Sotos J., Schuler L.A., Czuprynski C.J. Differential gene regulation of interleukin-1 ligands and receptors in bovine peripheral blood neutrophils and mononuclear cells in response to E. coli lipopolysaccharide (LPS). Vet. Immunol. Immunopathol. 77:2000;221-232.
    • (2000) Vet. Immunol. Immunopathol. , vol.77 , pp. 221-232
    • Beckman, M.J.1    Sotos, J.2    Schuler, L.A.3    Czuprynski, C.J.4
  • 6
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principal of protein-dye binding
    • Bradford M.M. A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principal of protein-dye binding. Anal. Biochem. 72:1976;248-254.
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 7
    • 0035865262 scopus 로고    scopus 로고
    • Role of endogenous interleukin-receptor antagonist in regulating fever by localised inflammation in the rat
    • 531.1
    • Cartmell T., Luheshi G.N., Hopkins S.J., Rothwell N.J., Poole S. Role of endogenous interleukin-receptor antagonist in regulating fever by localised inflammation in the rat. J. Physiol. 531.1:2001;171-180.
    • (2001) J. Physiol. , pp. 171-180
    • Cartmell, T.1    Luheshi, G.N.2    Hopkins, S.J.3    Rothwell, N.J.4    Poole, S.5
  • 9
    • 0028004236 scopus 로고
    • The type II 'decoy' receptor: A novel regulatory pathway for interleukin-1
    • Colotta F., Dower S.K., Sims J.E., Mantovani A. The type II 'decoy' receptor: a novel regulatory pathway for interleukin-1. Immunol. Today. 15:1994;562-566.
    • (1994) Immunol. Today , vol.15 , pp. 562-566
    • Colotta, F.1    Dower, S.K.2    Sims, J.E.3    Mantovani, A.4
  • 10
    • 0023953471 scopus 로고
    • Biology of interleukin-1
    • Dinarello C.A. Biology of interleukin-1. FASEB J. 2:1988;108-115.
    • (1988) FASEB J. , vol.2 , pp. 108-115
    • Dinarello, C.A.1
  • 11
    • 0029979369 scopus 로고    scopus 로고
    • Biologic basis for interleukin-1 in disease
    • Dinarello C.A. Biologic basis for interleukin-1 in disease. Blood. 87:1996;2095-2147.
    • (1996) Blood , vol.87 , pp. 2095-2147
    • Dinarello, C.A.1
  • 12
    • 0034618862 scopus 로고    scopus 로고
    • The role of interleukin-1 receptor antagonist in blocking inflammation mediated by interleukin-1
    • Dinarello C.A. The role of interleukin-1 receptor antagonist in blocking inflammation mediated by interleukin-1. N. Engl. J. Med. 343:2000;732-734.
    • (2000) N. Engl. J. Med. , vol.343 , pp. 732-734
    • Dinarello, C.A.1
  • 14
    • 0034967982 scopus 로고    scopus 로고
    • Whole-cell but not acellular pertussis vaccines induce convulsive activity in mice: Evidence of a role for toxin-induced interleukin-1beta in a new murine model for analysis of neuronal side effects of vaccination
    • Donnelly S., Loscher C.E., Lynch M.A., Mills K.H.G. Whole-cell but not acellular pertussis vaccines induce convulsive activity in mice: evidence of a role for toxin-induced interleukin-1beta in a new murine model for analysis of neuronal side effects of vaccination. Infect. Immun. 69:2001;4217-4223.
    • (2001) Infect. Immun. , vol.69 , pp. 4217-4223
    • Donnelly, S.1    Loscher, C.E.2    Lynch, M.A.3    Mills, K.H.G.4
  • 15
    • 0025021471 scopus 로고
    • Primary structure and functional expression from complementary DNA of a human interleukin-1 receptor antagonist
    • Eisenberg S.P., Evans R.J., Arend W.P., Verderber E., Brewer M.T., Hannum C.H., Thompson R.C. Primary structure and functional expression from complementary DNA of a human interleukin-1 receptor antagonist. Nature. 343:1990;341-346.
    • (1990) Nature , vol.343 , pp. 341-346
    • Eisenberg, S.P.1    Evans, R.J.2    Arend, W.P.3    Verderber, E.4    Brewer, M.T.5    Hannum, C.H.6    Thompson, R.C.7
  • 17
    • 0028978580 scopus 로고
    • Expression of interleukin-1α, interleukin-1β and interleukin-1 receptor antagonist mRNA in mouse brain: Regulation by bacterial lipopolysaccharide (LPS) treatment
    • Gabellec M.-M., Griffais R., Fillion G., Haour F. Expression of interleukin-1α, interleukin-1β and interleukin-1 receptor antagonist mRNA in mouse brain: regulation by bacterial lipopolysaccharide (LPS) treatment. Brain. Res. Mol. Brain. Res. 31:1995;122-130.
    • (1995) Brain. Res. Mol. Brain. Res. , vol.31 , pp. 122-130
    • Gabellec, M.-M.1    Griffais, R.2    Fillion, G.3    Haour, F.4
  • 18
    • 0030009045 scopus 로고    scopus 로고
    • Interleukin-1 receptors type I and type II in the mouse brain: Kinetics of mRNA expression after peripheral administration of bacterial lipopolysaccharide
    • Gabellec M.-M., Griffais R., Fillion G., Haour F. Interleukin-1 receptors type I and type II in the mouse brain: kinetics of mRNA expression after peripheral administration of bacterial lipopolysaccharide. J. Neuroimmunol. 66:1996;65-70.
    • (1996) J. Neuroimmunol. , vol.66 , pp. 65-70
    • Gabellec, M.-M.1    Griffais, R.2    Fillion, G.3    Haour, F.4
  • 19
    • 12644306846 scopus 로고    scopus 로고
    • Interleukin-1 receptor accessory protein transcripts in the brain and spleen: Kinetics after peripheral administration of bacterial lipopolysaccharide in mice
    • Gabellec M.-M., Jafarian-Tehrani M., Griffais R., Haour F. Interleukin-1 receptor accessory protein transcripts in the brain and spleen: kinetics after peripheral administration of bacterial lipopolysaccharide in mice. Neuroimmunomodulation. 3:1996;304-309.
    • (1996) Neuroimmunomodulation , vol.3 , pp. 304-309
    • Gabellec, M.-M.1    Jafarian-Tehrani, M.2    Griffais, R.3    Haour, F.4
  • 20
    • 0022441440 scopus 로고
    • Interleukin 1 of the central nervous system is produced by ameboid microglia
    • Giulian D., Baker T.J., Shih L.C., Lachman L.B. Interleukin 1 of the central nervous system is produced by ameboid microglia. J. Exp. Med. 164:1986;594-604.
    • (1986) J. Exp. Med. , vol.164 , pp. 594-604
    • Giulian, D.1    Baker, T.J.2    Shih, L.C.3    Lachman, L.B.4
  • 22
    • 0029009910 scopus 로고
    • Molecular cloning and characterization of a second subunit of the interleukin 1 receptor complex
    • Greenfeder S.A., Nunes P., Kwee L., Labow M., Chizzonite R.A., Ju G. Molecular cloning and characterization of a second subunit of the interleukin 1 receptor complex. J. Biol. Chem. 270:1995;13757-13765.
    • (1995) J. Biol. Chem. , vol.270 , pp. 13757-13765
    • Greenfeder, S.A.1    Nunes, P.2    Kwee, L.3    Labow, M.4    Chizzonite, R.A.5    Ju, G.6
  • 23
    • 0030058665 scopus 로고    scopus 로고
    • A controlled trial of a two-component acellular, a five-component acellular, and a whole-cell pertussis vaccine
    • Gustafsson L., Hallander H.O., Olin P., Reizenstein E., Storsaeter J. A controlled trial of a two-component acellular, a five-component acellular, and a whole-cell pertussis vaccine. N. Engl. J. Med. 334:1996;349-355.
    • (1996) N. Engl. J. Med. , vol.334 , pp. 349-355
    • Gustafsson, L.1    Hallander, H.O.2    Olin, P.3    Reizenstein, E.4    Storsaeter, J.5
  • 24
    • 0027517309 scopus 로고
    • Murine tumour necrosis factor alpha is transported from blood to brain in the mouse
    • Gutierrez E.G., Banks W.A., Kastin A.J. Murine tumour necrosis factor alpha is transported from blood to brain in the mouse. J. Neuroimmunol. 47:1993;169-176.
    • (1993) J. Neuroimmunol. , vol.47 , pp. 169-176
    • Gutierrez, E.G.1    Banks, W.A.2    Kastin, A.J.3
  • 25
    • 0028556463 scopus 로고
    • Blood-borne interleukin-1 receptor antagonist crosses the blood-brain barrier
    • Gutierrez E.G., Banks W.A., Kastin A.J. Blood-borne interleukin-1 receptor antagonist crosses the blood-brain barrier. J. Neuroimmunol. 55:1994;153-160.
    • (1994) J. Neuroimmunol. , vol.55 , pp. 153-160
    • Gutierrez, E.G.1    Banks, W.A.2    Kastin, A.J.3
  • 27
    • 0032534729 scopus 로고    scopus 로고
    • The type II IL-1 receptor interacts with the IL-1 receptor accessory protein: A novel mechanism of regulation of IL-1 responsiveness
    • Lang D., Knop J., Wesche H., Raffetseder U., Kurrle R., Boraschi D., Martin M.U. The type II IL-1 receptor interacts with the IL-1 receptor accessory protein: a novel mechanism of regulation of IL-1 responsiveness. J. Immunol. 161:1998;6871-6877.
    • (1998) J. Immunol. , vol.161 , pp. 6871-6877
    • Lang, D.1    Knop, J.2    Wesche, H.3    Raffetseder, U.4    Kurrle, R.5    Boraschi, D.6    Martin, M.U.7
  • 29
    • 0031739419 scopus 로고    scopus 로고
    • Proinflammatory cytokines in the adverse systemic and neurological effects associated with parenteral injection of a whole cell pertussis vaccine
    • Loscher C.E., Donnelly S., McBennett S., Lynch M.A., Mills K.H.G. Proinflammatory cytokines in the adverse systemic and neurological effects associated with parenteral injection of a whole cell pertussis vaccine. Ann. N.Y. Acad. Sci. 856:1998;274-277.
    • (1998) Ann. N.Y. Acad. Sci. , vol.856 , pp. 274-277
    • Loscher, C.E.1    Donnelly, S.2    McBennett, S.3    Lynch, M.A.4    Mills, K.H.G.5
  • 30
    • 0033991962 scopus 로고    scopus 로고
    • Induction of inflammatory cytokines in the brain following respiratory infection with Bordetella pertussis
    • Loscher C.E., Donnelly S., Lynch M.A., Mills K.H.G. Induction of inflammatory cytokines in the brain following respiratory infection with Bordetella pertussis. J. Neuroimmunol. 102:2000;172-181.
    • (2000) J. Neuroimmunol. , vol.102 , pp. 172-181
    • Loscher, C.E.1    Donnelly, S.2    Lynch, M.A.3    Mills, K.H.G.4
  • 31
    • 0034310721 scopus 로고    scopus 로고
    • Interleukin-1beta-dependent changes in the hippocampus following parenteral immunization with a whole cell pertussis vaccine
    • Loscher C.E., Donnelly S., Mills K.H.G., Lynch M.A. Interleukin-1beta-dependent changes in the hippocampus following parenteral immunization with a whole cell pertussis vaccine. J. Neuroimmunol. 111:2000;68-76.
    • (2000) J. Neuroimmunol. , vol.111 , pp. 68-76
    • Loscher, C.E.1    Donnelly, S.2    Mills, K.H.G.3    Lynch, M.A.4
  • 32
    • 0031849605 scopus 로고    scopus 로고
    • Relative contributions of a CVO and the microvascular bed to delivery of blood-borne IL-1α to the brain
    • Maness L.M., Kastin A.J., Banks W.A. Relative contributions of a CVO and the microvascular bed to delivery of blood-borne IL-1α to the brain. Endocrinol. Metab. 38:1998;E207-E212.
    • (1998) Endocrinol. Metab. , vol.38
    • Maness, L.M.1    Kastin, A.J.2    Banks, W.A.3
  • 34
    • 0030273773 scopus 로고    scopus 로고
    • ICE-like proteases execute the neuronal death program
    • Martinou J.-C., Sadoul R. ICE-like proteases execute the neuronal death program. Curr. Opin. Neurobiol. 6:1996;609-614.
    • (1996) Curr. Opin. Neurobiol. , vol.6 , pp. 609-614
    • Martinou, J.-C.1    Sadoul, R.2
  • 35
    • 0033970120 scopus 로고    scopus 로고
    • A regulatory role for IL-4 in differential inflammatory responses in the lung following infection of mice primed with Th1- or Th2-inducing pertussis vaccines
    • McGuirk P., Mills K.H.G. A regulatory role for IL-4 in differential inflammatory responses in the lung following infection of mice primed with Th1- or Th2-inducing pertussis vaccines. Infect. Immun. 68:2000;1383-1391.
    • (2000) Infect. Immun. , vol.68 , pp. 1383-1391
    • McGuirk, P.1    Mills, K.H.G.2
  • 36
    • 0033952395 scopus 로고    scopus 로고
    • Direct anti-inflammatory effect of a bacterial virulence factor: IL-10-dependent suppression of IL-12 production by filamentous haemagglutinin from Bordetella pertussis
    • McGuirk P., Mills K.H.G. Direct anti-inflammatory effect of a bacterial virulence factor: IL-10-dependent suppression of IL-12 production by filamentous haemagglutinin from Bordetella pertussis. Eur. J. Immunol. 30:2000;415-422.
    • (2000) Eur. J. Immunol , vol.30 , pp. 415-422
    • McGuirk, P.1    Mills, K.H.G.2
  • 37
    • 0037148511 scopus 로고    scopus 로고
    • Pathogen-specific T regulatory 1 (Tr1) cells induced in the respiratory tract by a bacterial molecule that stimulates IL-10 production by dendritic cells: A novel strategy for evasion of protective Th1 responses against Bordetella pertussis
    • McGuirk P., McCann C., Mills K.H.G. Pathogen-specific T regulatory 1 (Tr1) cells induced in the respiratory tract by a bacterial molecule that stimulates IL-10 production by dendritic cells: a novel strategy for evasion of protective Th1 responses against Bordetella pertussis. J. Exp. Med. 195:2002;221-231.
    • (2002) J. Exp. Med. , vol.195 , pp. 221-231
    • McGuirk, P.1    McCann, C.2    Mills, K.H.G.3
  • 39
    • 0019459394 scopus 로고
    • Pertussis immunisation and serious acute neurological illness in children
    • Miller D.L., Ross E.M., Alderslade R., Bellman M.H., Rawson N.S. Pertussis immunisation and serious acute neurological illness in children. Br. Med. J. 282:1981;1595-1599.
    • (1981) Br. Med. J. , vol.282 , pp. 1595-1599
    • Miller, D.L.1    Ross, E.M.2    Alderslade, R.3    Bellman, M.H.4    Rawson, N.S.5
  • 40
    • 0001679758 scopus 로고    scopus 로고
    • Induction and detection of T cell responses
    • A. Robinson. New Jersey, USA: Humana Press
    • Mills K.H.G. Induction and detection of T cell responses. Robinson A. Methods in Molecular Medicine-Vaccine Protocols. 1996;197-221 Humana Press, New Jersey, USA.
    • (1996) Methods in Molecular Medicine-Vaccine Protocols , pp. 197-221
    • Mills, K.H.G.1
  • 41
    • 0030582991 scopus 로고    scopus 로고
    • Interleukin (IL)-1 beta, IL-2, IL-4, IL-6 and transforming growth factor-alpha levels are elevated in ventricular cerebrospinal fluid in juvenile parkinsonism and Parkinson's disease
    • Mogi M., Harada M., Narabayashi H., Inagaki H., Minami M., Nagatsu T. Interleukin (IL)-1 beta, IL-2, IL-4, IL-6 and transforming growth factor-alpha levels are elevated in ventricular cerebrospinal fluid in juvenile parkinsonism and Parkinson's disease. Neurosci. Lett. 211:1996;13-16.
    • (1996) Neurosci. Lett. , vol.211 , pp. 13-16
    • Mogi, M.1    Harada, M.2    Narabayashi, H.3    Inagaki, H.4    Minami, M.5    Nagatsu, T.6
  • 42
    • 0034717887 scopus 로고    scopus 로고
    • Modulation of type I interleukin-1 receptor messenger RNA followed by one and repeated endotoxin treatment in the mouse
    • Nagano I., Takao T., Nanamiya W., Hashimoto K. Modulation of type I interleukin-1 receptor messenger RNA followed by one and repeated endotoxin treatment in the mouse. J. Neuroimmunol. 195:2000;154-160.
    • (2000) J. Neuroimmunol. , vol.195 , pp. 154-160
    • Nagano, I.1    Takao, T.2    Nanamiya, W.3    Hashimoto, K.4
  • 43
    • 0031590627 scopus 로고    scopus 로고
    • Randomised controlled trial of two-component, three-component, and five-component cellular pertussis vaccines compared with whole-cell pertussis vaccine. Ad Hoc Group for the Study of Pertussis Vaccines
    • Olin P., Rasmussen F., Gustafsson L., Hallander H.O., Heijbel H. Randomised controlled trial of two-component, three-component, and five-component cellular pertussis vaccines compared with whole-cell pertussis vaccine. Ad Hoc Group for the Study of Pertussis Vaccines. Lancet. 350:1997;1569-1577.
    • (1997) Lancet , vol.350 , pp. 1569-1577
    • Olin, P.1    Rasmussen, F.2    Gustafsson, L.3    Hallander, H.O.4    Heijbel, H.5
  • 46
    • 0034705350 scopus 로고    scopus 로고
    • IL-1β induced changes in hypothalamic IL-1RI and IL-1RII expression in the rat
    • Parker L.C., Rushford D.A., Rothwell N.J., Luheshi G.N. IL-1β induced changes in hypothalamic IL-1RI and IL-1RII expression in the rat. Mol. Brain Res. 79:2000;156-158.
    • (2000) Mol. Brain Res. , vol.79 , pp. 156-158
    • Parker, L.C.1    Rushford, D.A.2    Rothwell, N.J.3    Luheshi, G.N.4
  • 47
    • 0033105652 scopus 로고    scopus 로고
    • Bacterial lipopolysaccharide causes rapid shedding, followed by inhibition on mRNA expression of the IL-1 type II receptor, with concomitant up-regulation of the type I receptor and induction on incompletely spliced transcripts
    • Penton-Rol G., Orlando S., Polentarutti N., Bernasconi S., Muzio M., Introna M., Mantovani A. Bacterial lipopolysaccharide causes rapid shedding, followed by inhibition on mRNA expression of the IL-1 type II receptor, with concomitant up-regulation of the type I receptor and induction on incompletely spliced transcripts. J. Immunol. 162:1999;2931-2938.
    • (1999) J. Immunol. , vol.162 , pp. 2931-2938
    • Penton-Rol, G.1    Orlando, S.2    Polentarutti, N.3    Bernasconi, S.4    Muzio, M.5    Introna, M.6    Mantovani, A.7
  • 49
    • 0035286449 scopus 로고    scopus 로고
    • Fever induction pathways: Evidence from responses to systemic or local cytokine formation
    • Roth J., de Souza G.E.P. Fever induction pathways: evidence from responses to systemic or local cytokine formation. Braz. J. Med. Biol. Res. 34:2001;301-314.
    • (2001) Braz. J. Med. Biol. Res. , vol.34 , pp. 301-314
    • Roth, J.1    De Souza, G.E.P.2
  • 50
    • 0024358231 scopus 로고
    • Effect of hyperactivity to endotoxin on the toxicity of pertussis vaccine and pertussis toxin in mice
    • Sidey F.M., Furmean B.L., Wardlaw A.C. Effect of hyperactivity to endotoxin on the toxicity of pertussis vaccine and pertussis toxin in mice. Vaccine. 7:1989;237-241.
    • (1989) Vaccine , vol.7 , pp. 237-241
    • Sidey, F.M.1    Furmean, B.L.2    Wardlaw, A.C.3
  • 52
    • 0025954301 scopus 로고
    • Purification and characterization of a novel soluble receptor for interleukin 1
    • Symons J.A., Eastgate J.A., Duff G.W. Purification and characterization of a novel soluble receptor for interleukin 1. J. Exp. Med. 174:1991;1251-1254.
    • (1991) J. Exp. Med. , vol.174 , pp. 1251-1254
    • Symons, J.A.1    Eastgate, J.A.2    Duff, G.W.3
  • 53
    • 0033387565 scopus 로고    scopus 로고
    • Potential mechanisms of interleukin-1 involvement in cerebral ischaemia
    • Touzani O., Boutin H., Chuquet J., Rothwell N. Potential mechanisms of interleukin-1 involvement in cerebral ischaemia. J. Neuroimmunol. 100:1999;203-215.
    • (1999) J. Neuroimmunol. , vol.100 , pp. 203-215
    • Touzani, O.1    Boutin, H.2    Chuquet, J.3    Rothwell, N.4
  • 54
    • 0034666435 scopus 로고    scopus 로고
    • The inhibitory effect of interleukin-1beta on long-term potentiation is coupled with increased activity of stress-activated protein kinases
    • Vereker E., O'Donnell E., Lynch M.A. The inhibitory effect of interleukin-1beta on long-term potentiation is coupled with increased activity of stress-activated protein kinases. J. Neurosci. 20:2000;6811-6819.
    • (2000) J. Neurosci. , vol.20 , pp. 6811-6819
    • Vereker, E.1    O'Donnell, E.2    Lynch, M.A.3
  • 55
    • 0034656412 scopus 로고    scopus 로고
    • Interleukin-1beta immunoreactivity in identified neurons of the rat magnocellular neurosecretory system: Evidence for activity-dependent release
    • Watt J.A., Hobbs N.K. Interleukin-1beta immunoreactivity in identified neurons of the rat magnocellular neurosecretory system: evidence for activity-dependent release. J. Neurosci. Res. 60:2000;478-489.
    • (2000) J. Neurosci. Res. , vol.60 , pp. 478-489
    • Watt, J.A.1    Hobbs, N.K.2
  • 56
    • 0030570823 scopus 로고    scopus 로고
    • Co-expression of mRNA for type I and type II interlukin-1 receptors and the IL-1 receptor accessory protein correlates to IL-1 responsiveness
    • Wesche H., Neumann D., Resch K., Martin M.U. Co-expression of mRNA for type I and type II interlukin-1 receptors and the IL-1 receptor accessory protein correlates to IL-1 responsiveness. FEBS Lett. 391:1996;104-108.
    • (1996) FEBS Lett. , vol.391 , pp. 104-108
    • Wesche, H.1    Neumann, D.2    Resch, K.3    Martin, M.U.4
  • 57
    • 0030614340 scopus 로고    scopus 로고
    • Interleukin (IL) 1β, IL-1 receptor antagonist, IL-10 and IL-13 gene expression in the central nervous system and anterior pituitary during systemic inflammation: Pathophysiological implications
    • Wong M., Bongiorno P., Rettori V., McCann S., Licinio J. Interleukin (IL) 1β, IL-1 receptor antagonist, IL-10 and IL-13 gene expression in the central nervous system and anterior pituitary during systemic inflammation: pathophysiological implications. Proc. Natl. Acad. Sci. U. S. A. 94:1997;227-232.
    • (1997) Proc. Natl. Acad. Sci. U. S. A. , vol.94 , pp. 227-232
    • Wong, M.1    Bongiorno, P.2    Rettori, V.3    McCann, S.4    Licinio, J.5
  • 58
    • 0026757091 scopus 로고
    • Characterization of interleukin-1 production by microglia in culture
    • Yao J., Keri J.E., Taffs R.E., Colton C.A. Characterization of interleukin-1 production by microglia in culture. Brain Res. 591:1992;88-93.
    • (1992) Brain Res. , vol.591 , pp. 88-93
    • Yao, J.1    Keri, J.E.2    Taffs, R.E.3    Colton, C.A.4


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