Relative contributions of a CVO and the microvascular bed to delivery of blood-borne IL-1α to the brain

American Journal of Physiology - Endocrinology and Metabolism

Volumn 275, Issue 2 38-2, 1998, Pages

  Maness, Lawrence M ^a,b   Kastin, Abba J ^a   Banks, William A ^a  

^a TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Autoradiography; Blood brain barrier; Circumventricular organ; Cytokine; Interleukin 1 ; Mouse; Subfornical organ; Transport

Indexed keywords

INTERLEUKIN 1ALPHA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BLOOD; BLOOD BRAIN BARRIER; BRAIN; CAPILLARY; DIFFUSION; MALE; MEMBRANE TRANSPORT; MICROVASCULATURE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SUBFORNICAL ORGAN;

EID: 0031849605     PISSN: 01931849     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpendo.1998.275.2.e207     Document Type: Article

References (18)

1. Banks, W. A., and A. J. Kastin. Blood to brain transport of interleukin links the immune and central nervous systems. Life Sci. 48: PL117-PL121, 1991.
2. Banks, W. A., A. J. Kastin, and D. A. Durham. Bidirectional transport of interleukin-1 alpha across the blood-brain barrier. Brain Res. Bull. 23: 433-437, 1989.
3. Banks, W. A., A. J. Kastin, H. M. Sam, V. T. Cao, B. King, L. M. Maness, and A. V. Schally. Saturable efflux of the peptides RC-160 and Tyr-MIF-1 by different parts of the blood-brain barrier. Brain Res. Bull. 35: 179-182, 1994.
4. Banks, W. A., L. Ortiz, S. R. Plotkin, and A. J. Kastin. Human interleukin (IL) 1 alpha, murine IL-1 alpha and murine IL-1 beta are transported from blood to brain in the mouse by a shared saturable mechanism. J. Pharmacol. Exp. Ther. 259: 988-996, 1991.
5. Brightman, M. W., and S. E. Palay. The fine structure of ependyma in the brain of the rat. J. Cell Biol. 19: 415-439, 1963.
6. Cserr, H. F., and B. J. Herman. Iodide and thiocyanate efflux from brain following injection into rat caudate nucleus. Am. J. Physiol. 235 (Renal Fluid Electrolyte Physiol. 4): F331-F337, 1978.
7. Cunningham, E. T., Jr., and E. B. De Souza. Interleukin 1 receptors in the brain and endocrine tissues. Immunol. Today 14: 171-176, 1993.
8. Cunningham, E. T., Jr., E. Wade, D. B. Carter, D. E. Tracey, J. F. Battey, and E. B. De Souza. In situ histochemical localization of type I interleukin-1 receptor messenger RNA in the central nervous system, pituitary, and adrenal gland of the mouse. J. Neurosci. 12: 1101-1114, 1992.
9. Dermietzel, R., and D. Krause. Molecular anatomy of the blood-brain barrier as defined by immunocytochemistry. Int. Rev. Cytol. 127: 57-109, 1991.
10. Farrar, W. L., P. L. Kilian, M. R. Ruff, J. M. Hill, and C. B. Pert. Visualization and characterization of interleukin 1 receptors in brain. J. Immunol. 139: 459-463, 1987.
11. Gutierrez, E. G., W. A. Banks, and A. J. Kastin. Murine tumor necrosis factor alpha is transported from blood to brain in the mouse. J. Neuroimmunol. 47: 169-176, 1993.
12. Gutierrez, E. G., W. A. Banks, and A. J. Kastin. Blood-borne interleukin-1 receptor antagonist crosses the blood-brain barrier. J. Neuroimmunol. 55: 153-160, 1994.
13. Krisch, B., H. Leonhardt, and W. Buchheim. The functional and structural border between the CSF- and blood-milieu in the circumventricular organs (organum vasculosum laminae terminalis, subfornical organ, area postrema) of the rat. Cell Tissue Res. 195: 485-497, 1978.
14. Maness, L. M., W. A. Banks, J. E. Zadina, and A. J. Kastin. Selective transport of blood-borne interleukin-1 into the posterior division of the septum of the mouse brain. Brain Res. 700: 83-88, 1995.
15. Maness, L. M., W. A. Banks, J. E. Zadina, and A. J. Kastin. Periventricular penetration and disappearance of ICV Tyr-MIF-1, DAMGO, tyrosine, and albumin. Peptides 17: 247-250, 1996.
16. Petrov, T., A. G. Howarth, T. L. Krukoff, and B. R. Stevenson. Distribution of tight junction-associated protein ZO-1 in circumventricular organs of the CNS. Mol. Brain Res. 21: 235-246, 1994.
17. Van Deurs, B. Structural aspects of brain barriers, with special reference to the permeability of the cerebral endothelium and choroid plexus. Int. Rev. Cytol. 65: 117-191, 1980.
18. Wong, M. L., and J. Licinio. Localization of interleukin 1 type 1 receptor mRNA in the rat brain. Neuroimmunomodulation 1: 110-115, 1994.