Synthesis and cytotoxicity of dihydroartemisinin ethers containing cyanoarylmethyl group

Bioorganic and Medicinal Chemistry

Volumn 11, Issue 6, 2003, Pages 977-984

  Li, Ying ^a,d   Wu, Jin Ming ^a   Shan, Feng ^a   Wu, Guang Shao ^a   Ding, Jian ^a   Xiao, Dong ^a   Han, Jia Xian ^a   Atassi, Ghanem ^b   Leonce, Stéphane ^b   Caignard, Daniel Henri ^c   Renard, Pierre ^c  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^b INSTITUT DE RECHERCHES INTERNATIONALES SERVIER   (France)

^c ADIR   (France)

^d NONE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

(CYANOMETHYL)BENZYL 12BETA DEOXOARTEMISINYL ETHER; CYANO(1' NAPHTHYL)METHYL 12BETA DEOXOARTEMISINYL ETHER; CYANO(2 BROMOPHENYL)METHYL 12BETA DEOXOARTEMISINYL ETHER; CYANO(2 CHLOROPHENYL)METHYL 12BETA DEOXOARTEMISINYL ETHER; CYANO(2 FLUOROPHENYL)METHYL 12BETA DEOXOARTEMISINYL ETHER; CYANO(2' NAPHTHYL)METHYL 12BETA DEOXOARTEMISINYL ETHER; CYANO(2,4 DIMETHOXYPHENYL)METHYL 12BETA DEOXOARTEMISINYL ETHER; CYANO(2,4 DIMETHYLPHENYL)METHYL 12BETA DEOXOARTEMISINYL ETHER; CYANO(3 BROMOPHENYL)METHYL 12BETA DEOXOARTEMISINYL ETHER; CYANO(3,4 DIMETHOXYPHENYL)METHYL 12BETA DEOXOARTEMISINYL ETHER; CYANO(4 BROMOPHENYL)METHYL 12BETA DEOXOARTEMISINYL ETHER; CYANO(4 BROMOPHENYL)METHYL 12BETA DEOXODEOXYARTEMISINYL ETHER; CYANO(4 CHLOROPHENYL)METHYL 12BETA DEOXOARTEMISINYL ETHER; CYANO(4 FLUOROPHENYL)METHYL 12BETA DEOXOARTEMISINYL ETHER; CYANO(9 ANTHRYL)METHYL 12BETA DEOXOARTEMISINYL ETHER; CYANO[3 (3' TRIFLUOROPHENOXY)PHENYL]METHYL 12BETA DEOXOARTEMISINYL ETHER; CYANOPHENYLMETHYL 12BETA DEOXOARTEMISINYL ETHER; CYTOTOXIC AGENT; DIHYDROARTEMISININ DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; ASSAY; CANCER CELL; CELL CYCLE; COLON ADENOCARCINOMA; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVITY; DRUG POTENCY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; FLOW CYTOMETRY; HUMAN; HUMAN CELL; ISOMERISM; LEUKEMIA CELL LINE; MOUSE; NONHUMAN; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; ARTEMISIA; DRUG SCREENING ASSAYS, ANTITUMOR; ETHERS; FLOW CYTOMETRY; G1 PHASE; HT29 CELLS; HUMANS; LEUKEMIA L1210; LEUKEMIA P388; MICE; NITRILES; TETRAZOLIUM SALTS; THIAZOLES;

EID: 0037333343     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(02)00538-2     Document Type: Article

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