Does ischemic preconditioning reduce spinal cord injury because of descending thoracic aortic occlusion?

Journal of Vascular Surgery

Volumn 37, Issue 2, 2003, Pages 426-432

  Toumpoulis, Ioannis K ^a   Anagnostopoulos, Constantine E ^a,b   Drossos, George E ^a   Malamou Mitsi, Vassiliki D ^a   Pappa, Lina S ^a   Katritsis, Demosthenes G ^a  

^a UNIVERSITY HOSPITAL OF IOANNINA   (Greece)

^b Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EOSIN; HEMATOXYLIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA BIFURCATION; AORTA OCCLUSION; ARTICLE; BALLOON CATHETER; BALLOON OCCLUSION; CELL COUNT; CONTROLLED STUDY; DESCENDING AORTA; FEMALE; FLUOROSCOPY; GRAY MATTER; HEART INFARCTION PREVENTION; HISTOLOGY; INFLAMMATION; LUMBAR SPINAL CORD; MALE; NERVE CELL; NEUROLOGIC EXAMINATION; NONHUMAN; PRIORITY JOURNAL; PROTECTION; RATING SCALE; SPINAL CORD INJURY; SWINE; THORACIC AORTA; THORACIC SPINAL CORD;

EID: 0037328654     PISSN: 07415214     EISSN: None     Source Type: Journal    
DOI: 10.1067/mva.2003.1     Document Type: Article

References (31)

1. Cambria RP, Davison JK, Carter C, Brewster DC, Chang Y, Clark KA, et al. Epidural cooling for spinal cord protection during thoracoabdominal aneurysm repair: a five-year experience. J Vasc Surg 2000;31:1093-102.
2. Estrera AL, Miller CC III, Huynh TT, Porat E, Safi HJ. Neurologic outcome after thoracic and thoracoabdominal aortic aneurysm repair. Ann Thorac Surg 2001;72:1225-30.
3. Bavaria JE, Woo YJ, Hall RA, Carpenter JP, Gardner TJ. Retrograde cerebral and distal aortic perfusion during ascending and thoracoabdominal aortic operations. Ann Thorac Surg 1995;60:345-52.
4. Svensson LG, Crawford ES, Hess KR, Coselli JS, Safi HJ. Experience with 1509 patients undergoing thoracoabdominal aortic operations. J Vasc Surg 1993;17:357-68.
5. Griepp RB, Ergin MA, Galla JD, Lansman S, Khan N, Quintana C, et al. Looking for the artery of Adamkiewicz: a quest to minimize paraplegia after operations for aneurysms of the descending thoracic and thoracoabdominal aorta. J Thorac Cardiovasc Surg 1996;112:1202-13.
6. Acher CW, Wynn MM, Hoch JR, Kranner PW. Cardiac function is a risk factor for paralysis in thoracoabdominal aortic replacement. J Vasc Surg 1998;27:821-8.
7. Gilling-Smith GL, Worswick L, Knight PF, Wolfe JH, Mansfield AO. Surgical repair of thoracoabdominal aortic aneurysm: 10 years' experience. Br J Surg 1995;82:624-9.
8. Kouchoukos NT, Masetti P, Rokkas CK, Murphy SF, Blackstone EH. Safety and efficacy of hypothermic cardiopulmonary bypass and circulatory arrest for operations on the descending thoracic and thoracoabdominal aorta. Ann Thorac Surg 2001;72:699-707.
9. Coselli JS, LeMaire SA, Conklin LD, Koksoy C, Schmittling ZC. Morbidity and mortality after extent II thoracoabdominal aortic aneurysm repair. Ann Thorac Surg 2002;73:1107-16.
10. Sastry PS, Rao KS. Apoptosis and the nervous system. J Neurochem 2000;74:1-20.
11. Neumar RW. Molecular mechanisms of ischemic neuronal injury. Ann Emerg Med 2000;36:483-506.
12. de Haan P. Pharmacologic adjuncts to protect the spinal cord during transient ischemia. Semin Vasc Surg 2000;13:264-71.
13. Safi HJ, Hess KR, Randel M, Iliopoulos DC, Baldwin JC, Mootha RK, et al. Cerebrospinal fluid drainage and distal aortic perfusion: reducing neurologic complications in repair of thoracoabdominal aortic aneurysm types I and II. J Vasc Surg 1996;23:223-8.
14. Safi HJ, Miller CC III, Carr C, Iliopoulos DC, Dorsay DA, Baldwin JC. Importance of intercostal artery reattachment during thoracoabdominal aortic aneurysm repair. J Vasc Surg 1998;27:58-66.
15. Zvara DA, Colonna DM, Deal DD, Vernon JC, Gowda M, Lundell JC. Ischemic preconditioning reduces neurologic injury in a rat model of spinal cord ischemia. Ann Thorac Surg 1999;68:874-80.
16. Abraham VS, Swain JA, Forgash AJ, Williams BL, Musulin MM. Ischemic preconditioning protects against paraplegia after transient aortic occlusion in the rat. Ann Thorac Surg 2000;69:475-9.
17. Tarlov IM. Spinal cord compression: mechanisms of paralysis and treatment. Springfield (IL): Charles C. Thomas; 1957. p. 147.
18. Korthuis RJ, Gute DC, Cepinska G, Kvietys PR. Cellular mechanisms of acute versus delayed preconditioning. Pathophysiology 1998;5:35-48.
19. Bolli R. The late phase of preconditioning. Circ Res 2000;87:972-83.
20. Raeburn CD, Cleveland JC Jr, Zimmerman MA, Harken AH. Organ preconditioning. Arch Surg 2001;136:1263-6.
21. Matsuyama K, Chiba Y, Ihaya A, Kimura T, Tanigawa N, Muraoka R. Effect of spinal cord preconditioning on paraplegia during cross-clamping of the thoracic aorta. Ann Thorac Surg 1997;63:1315-20.
22. Sakurai M, Hayashi T, Abe K, Aoki M, Sadahiro M, Tabayashi K. Enhancement of heat shock protein expression after transient ischemia in the preconditioned spinal cord of rabbits. J Vasc Surg 1998;27:720-5.
23. de Haan P, Vanicky I, Jacobs MJ, Bakker O, Lips J, Meylaerts SA, et al. Effect of ischemic pretreatment on heat shock protein 72, neurologic outcome, and histopathologic outcome in a rabbit model of spinal cord ischemia. J Thorac Cardiovasc Surg 2000;120:513-9.
24. Parrino PE, Kron IL, Ross SD, Shockey KS, Fisher MJ, Gaughen JR Jr, et al. Retrograde venous perfusion with hypothermic saline and adenosine for protection of the ischemic spinal cord. J Vasc Surg 2000;32:171-8.
25. 2a receptor expression on motor neurons. Proceedings of the 38th Annual Meeting of the Society for Thoracic Surgeons; 2002 Jan 28-30; Fort Lauderdale, Fla. Chicago: STS.
26. Carden DL, Granger DN. Pathophysiology of ischaemia-reperfusion injury. J Pathol 2000;190:255-66.
27. Turkoz A, Turkoz R, Yorukoglu K, Onat U, Sagyroglu E, Sagban M. Evaluation of pentoxifylline in experimental spinal cord ischemia. Eur J Cardiothorac Surg 1997;12:648-53.
28. Hayashi T, Sakurai M, Abe K, Sadahiro M, Tabayashi K, Itoyama Y. Apoptosis of motor neurons with induction of caspases in the spinal cord after ischemia. Stroke 1998;29:1007-12.
29. Mackey ME, Wu Y, Hu R, DeMaro JA, Jacquin MF, Kanellopoulos GK, et al. Cell death suggestive of apoptosis after spinal cord ischemia in rabbits. Stroke 1997;28:2012-7.
30. Sakurai M, Hayashi T, Abe K, Sadahiro M, Tabayashi K. Delayed and selective motor neuron death after transient spinal cord ischemia: a role of apoptosis? J Thorac Cardiovasc Surg 1998;115:1310-5.
31. Toumpoulis IK, Anagnostopoulos CE, Drossos GE, Malamou-Mitsi V, Pappa LS, Katritsis DG. Early ischemic preconditioning without hypotension prevents spinal cord injury due to descending thoracic aortic occlusion. Proceedings of the 82nd Annual Meeting of the American Association for Thoracic Surgery; 2002 May 5-8; Washington, DC. J Thorac Cardiovasc Surg. In press 2002.