Nonbenzamidine tetrazole derivatives as factor Xa inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 13, Issue 3, 2003, Pages 369-373

  Quan, Mimi L ^a   Ellis, Christopher D ^a   He, Ming Y ^a   Liauw, Ann Y ^a   Woerner, Francis J ^a   Alexander, Richard S ^a   Knabb, Robert M ^a   Lam, Patrick Y S ^a   Luettgen, Joseph M ^a   Wong, Pancras C ^a   Wright, Matthew R ^a   Wexler, Ruth R ^a  

^a BRISTOL MYERS SQUIBB   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTITHROMBOCYTIC AGENT; BENZAMIDINE DERIVATIVE; BLOOD CLOTTING FACTOR 10A INHIBITOR; SR 374; TETRAZOLE DERIVATIVE; THROMBIN INHIBITOR; TRYPSIN INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG ACTIVITY; DRUG BIOAVAILABILITY; DRUG CLEARANCE; DRUG EFFICACY; DRUG HALF LIFE; DRUG POTENCY; DRUG SELECTIVITY; DRUG SYNTHESIS; MOLECULAR MIMICRY; NONHUMAN; STRUCTURE ACTIVITY RELATION;

ANIMALS; BIOLOGICAL AVAILABILITY; DOGS; FACTOR XA; HUMANS; KINETICS; MODELS, MOLECULAR; MOLECULAR MIMICRY; PROTEIN CONFORMATION; RABBITS; SERINE PROTEINASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP; TETRAZOLES; THROMBIN; TRYPSIN INHIBITORS;

EID: 0037325621     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(02)00951-4     Document Type: Article

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