Process characterization of the chromatographic steps in the purification process of a recombinant escherichia coli-expressed protein

Biotechnology and Applied Biochemistry

Volumn 37, Issue 1, 2003, Pages 51-61

  Rathore, Anurag S ^a   Johnson, Gary V ^a   Buckley, John J ^a   Boyle, Denis M ^a   Gustafson, Mark E ^a  

^a PFIZER INC   (United States)

Author keywords

Growth factor; Process development; Progenipoietin; Resin screening; SD 9427

Indexed keywords

CHROMATOGRAPHIC ANALYSIS; PH; PROTEINS; PURIFICATION; RESINS;

PROTEIN LOADING;

ESCHERICHIA COLI;

ARTICLE; CELL PROLIFERATION; CHROMATOGRAPHY; DENDRITIC CELL; ESCHERICHIA COLI; FERMENTATION; FLOW RATE; GOOD MANUFACTURING PRACTICE; HOST CELL; NONHUMAN; PROCESS DEVELOPMENT; PROTEIN EXPRESSION; PROTEIN PURIFICATION; ULTRAFILTRATION;

ALGORITHMS; BACTERIAL PROTEINS; CHROMATOGRAPHY; COLONY-STIMULATING FACTORS; DECISION SUPPORT TECHNIQUES; ESCHERICHIA COLI; QUALITY CONTROL; RECOMBINANT PROTEINS;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 0037325537     PISSN: 08854513     EISSN: None     Source Type: Journal    
DOI: 10.1042/BA20020068     Document Type: Article

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