Interactions of bacterial pathogens with dendritic cells during invasion of mucosal surfaces

Current Opinion in Microbiology

Volumn 6, Issue 1, 2003, Pages 72-76

  Granucci, Francesca ^a   Ricciardi Castagnoli, Paola ^a  

^a UNIVERSITY OF MILANO BICOCCA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE; CYTOKINE;

ANTIGEN RECOGNITION; BACTERIUM; CELL INVASION; CYTOKINE PRODUCTION; DENDRITIC CELL; HOST PATHOGEN INTERACTION; INTESTINE MUCOSA; LAMINA PROPRIA; MUCOSAL IMMUNITY; REVIEW;

BACTERIA (MICROORGANISMS);

EID: 0037325009     PISSN: 13695274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1369-5274(03)00007-9     Document Type: Review

References (24)

1. Cebra J, Jiang H, Sterzl J, Tlaskalova-Hogenova H: The role of mucosal microbiota in the development and maintenance of the mucosal immune system. In Mucosal Immunology. Edited by Ogra P et al. New York: Academic Press; 1998:267-280.
2. Shroff KE, Meslin K, Cebra JJ: Commensal enteric bacteria engender a self-limiting humoral mucosal immune response while permanently colonizing the gut. Infect Immun 1995, 63:3904-3913.
3. Banchereau J, Steinman RM: Dendritic cells and the control of immunity. Nature 1998, 392:245-252.
4. Ruedl C, Hubele S: Maturation of Peyer's patch dendritic cells in vitro upon stimulation via cytokines or CD40 triggering. Eur J Immunol 1997, 27:1325-1330.
5. Kelsall BL, Strober W: Distinct populations of dendritic cells are present in subepithelial dome and T cell regions of the murine Peyer's patch. J Exp Med 1996, 183:237-247.
6. Iwasaki A, Kelsall BL: Localization of distinct Peyer's patch dendritic cell subsets and their recruitment by chemokines macrophage inflammatory protein (MIP)-3α, MIP-3β, and secondary lymphoid organ chemokine. J Exp Med 2000, 191:1381-1394.
7. Maric I, Holt PG, Perdue MH, Bienstock J: Class II MHC antigen (Ia)-bearing dendritic cells in the epithelium of the rat intestine. J Immunol 1996, 156:1408-1414.
8. Hopkins S, Niedergang F, Corthésy-Theulaz IE, Kraehenbuhl JP: A recombinant Salmonella typhimurium vaccine strain is taken up and survives within murine Peyer's patch dendritic cells. Cell Microbiol 2000, 2:56-68.
9. Rescigno M, Urbano M, Valzasina B, Francolini M, Rotta G, Bonasio R, Granucci F, Kraehenbuhl JP, Ricciardi-Castagnoli P: Dendritic cells express tight junction proteins and penetrate gut epithelial monolayers to sample bacteria. Nat Immunol 2001, 2:361-368. This study illustrates a mechanism that allows lamina propria DCs to open the tight junctions between epithelial cells, preserving the integrity of the mucosal barrier and sampling microbes from the gut lumen.
10. Madara JL, Nash S, Moore R, Atisook K: Structure and function of the intestinal epithelial barrier in health and disease. Monogr Pathol 1990, 31:306-324.
11. Inman LR, Cantey JR: Specific adherence of Escherichia coli (strain RDEC-1) to membranous (M) cells of the Peyer's patch in Escherichia coli diarrhoea in the rabbit. J Clin Invest 1983, 71:1-10.
12. Wassef JS, Keren DF, Mailloux JL: Role of M cells in initial antigen uptake and in ulcer formation in the rabbit intestinal loop model of shigellosis. Infect Immun 1989, 57:858-865.
13. Kohbata S, Yokoyama H, Yabuuchi E: Cytopathogenic effect of Salmonella typhi GIFU 10007 on M cells of murine ileal Peyer's patches in ligated ileal loops: an ultrastructural study. Microbiol Immunol 1986, 30:1225-1232.
14. Galan JE, Curtiss R: Cloning and molecular characterization of genes whose products allow Salmonella typhimurium to penetrate tissue culture cells. Proc Natl Acad Sci USA 1989, 86:6383-6388.
15. Janeway CA, Medzhitov R: Innate immune recognition. Annu Rev Immunol 2002, 20:197-216. This review illustrates how the innate immune response is mediated by the Toll-like family of receptors.
16. Pearson AM: Scavenger receptors in innate immunity. Curr Opin Immunol 1996, 8:20-28.
17. Ricciardi-Castagnoli P, Granucci F: Functional genomic interpretation of innate immune response complexity. Nat Rev Immunol 2002, 2:881-889. This study illustrates how global gene expression analyses might provide unanticipated new insights into the complexity of innate responses.
18. Granucci F, Vizzardelli C, Pavelka N, Feau S, Persico M, Virzi E, Rescigno M, Moro G, Ricciardi-Castagnoli P: Inducible IL-2 production by dendritic cells revealed by global gene expression analysis. Nat Immunol 2001, 2:882-888. This study illustrates for the first time the ability of DCs to produce IL-2 and provides a molecular mechanism for the unique role of DCs in T cell priming and NK activation.
19. Granucci F, Andrews DM, Degli-Esposti MP, Ricciardi-Castagnoli P: IL2 mediates adjuvant effect of dendritic cells. Trends Immunol 2002, 23:169-171.
20. Furtado GC, Curotto de Lafaille M, Kutchukhidze N, Lafaille J: Interleukin 2 signaling is required for CD4+ regulatory T cell function. J Exp Med 2002, 196:851-857.
21. Sadlack B, Merz H, Schorle H, Schimpl A, Feller AC, Horak I: Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene. Cell 1993, 75:253-261.
22. Macpherson AJ, Gatto D, Sainsbury E, Harriman GR, Hengartner H, Zinkernagel RM: A primitive T-cell independent mechanism of intestinal mucosal IgA responses to commensal bacteria. Science 2000, 288:2222-2226.
23. Macpherson AJ, Lamarre A, McCoy K, Harriman GR, Odermatt B, Dougan G, Hengartner H, Zinkernagel RM: IgA production without mu or delta chain expression in developing B cells. Nat Immunol 2001, 2:625-631.
24. Huang FP, Platt N, Wykes M, Major JR, Powell TJ, Jenkins CD, MacPherson G: A discrete subpopulation of dendritic cells transports apoptotic intestinal epithelial cells to T cell areas of mesenteric lymph nodes. J Exp Med 2000, 191:435-443.