Surgical restoration of portal flow corrects procoagulant and anticoagulant deficiencies associated with extrahepatic portal vein thrombosis

Journal of Pediatrics

Volumn 142, Issue 2, 2003, Pages 197-199

  Mack, Cara L ^a   Superina, Riccardo A ^a   Whitington, Peter F ^a,b  

^a NORTHWESTERN UNIVERSITY   (United States)

^b CHILDREN'S MEMORIAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICOAGULANT AGENT; ANTITHROMBIN III; BLOOD CLOTTING FACTOR 5; BLOOD CLOTTING FACTOR 7; BLOOD CLOTTING FACTOR 8; D DIMER; PROCOAGULANT; PROTEIN C; PROTEIN S; PROTHROMBIN;

ARTICLE; BLOOD CLOTTING FACTOR DEFICIENCY; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; FOLLOW UP; HUMAN; IDIOPATHIC DISEASE; LABORATORY TEST; LIVER SURGERY; MALE; MESENTERIC ARTERY; PARTIAL THROMBOPLASTIN TIME; PORTAL VEIN BLOOD FLOW; PORTAL VEIN THROMBOSIS; POSTOPERATIVE PERIOD; PREOPERATIVE EVALUATION; PRIORITY JOURNAL; PROTHROMBIN TIME; SPLENORENAL SHUNT; SURGICAL TECHNIQUE; TREATMENT OUTCOME; VEIN BYPASS;

EID: 0037324149     PISSN: 00223476     EISSN: None     Source Type: Journal    
DOI: 10.1067/mpd.2003.93     Document Type: Article

References (12)

1. Alonso EM, Hackworth C, Whitington PF. Portal hypertension in children. Clin Liver Dis 1997;1:201-22.
2. Alvarez F, Bernard O, Brunelle F, Hadchouel P, Odievre M, Alagille D. Portal obstruction in children. I. Clinical investigation and hemorrhage risk. J Pediatr 1983;103:696-702.
3. Robson SC, Kahn D, Kruskal J, Bird AR, Kitsch RE. Disordered hemostasis in extrahepatic portal hypertension. Hepatology 1993;18:853-7.
4. Fisher NC, Wilde JT, Roper J, Elias E. Deficiency of natural anticoagulant proteins C, S, and antithrombin in portal vein thrombosis: a secondary phenomenon? Gut 2000;46:534-9.
5. Kim DI, Lee BB, Noh SI, Baek YH, Joh JW, Lee SK, Kim YI. Conservative management of superior mesenteric and portal vein thrombosis associated with protein C and S deficiency. Case report. Int Angiol 1997;16:235-8.
6. Dubuisson C, Boyer-Neumann C, Wolf M, Meyer D, Bernard O. Protein C, protein S, and antithrombin III in children with portal vein obstruction. J Hepatol 1997;27:132-5.
7. Orozco H, Guraieb E, Takahashi T, Garcia-Tsao G, Hurtado R, Anaya R, et al. Deficiency of protein C in patients with portal vein thrombosis. Hepatology 1988;8:1110-1.
8. Arav-Boger R, Reif S, Bujanover Y. Portal vein thrombosis caused by protein C and protein S deficiency associated with cytomegalovirus infection. J Pediatr 1995;126:586-8.
9. Bambini DA, Superina R, Almond PS, Whitington PF, Alonso E. Experience with the Rex shunt (mesenterico-left portal bypass) in children with extrahepatic portal hypertension. J Pediatr Surg 2000;35:13-8.
10. de Ville de Goyet J, Alberti D, Falchetti D, Rigamonti W, Matricardi L, Clapuyt P, et al. Treatment of extrahepatic portal hypertension in children by mesenteric-to-left portal vein bypass: a new physiological procedure. Eur J Surg 1999;165:777-81.
11. Lee YH, Alberta JA, Gonzalez FJ, Waxman DJ. Multiple, functional DBP sites on the promoter of the cholesterol 7 α-hydroxylase P450 gene, CYP7. Proposed role in diurnal regulation of liver gene expression. J Biol Chem 1994;269:14681-9.
12. McCarty MF. Hepatic monitoring of essential amino acid availability may regulate IGF-I activity, thermogenesis, and fatty, acid oxidation/synthesis. Med Hypotheses 2001;56:220-4.