Hepatic monitoring of essential amino acid availability may regulate IGF-I activity, thermogenesis, and fatty acid oxidation/synthesis

Medical Hypotheses

Volumn 56, Issue 2, 2001, Pages 220-224

  McCarty, M F ^a  

^a Pantox Laboratories   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ESSENTIAL AMINO ACID; SOMATOMEDIN C;

ARTICLE; FATTY ACID OXIDATION; FATTY ACID SYNTHESIS; INSULIN RELEASE; LIPOGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTAKE; PROTEIN QUALITY; THERMOGENESIS;

EID: 0035092257     PISSN: 03069877     EISSN: None     Source Type: Journal    
DOI: 10.1054/mehy.2000.1154     Document Type: Article

References (58)

1. Nutritional regulation of the insulin-like growth factors
2. Hormonal and nutritional regulation of IGF-I and its binding proteins
3. The effect of quantity and nutritional quality of dietary proteins on plasma concentration of insulin-like growth factor binding proteins (IGFBP) and the saturability of IGFBP with endogenous IGF-I
4. Induction of insulin-like growth factor binding protein-1 gene expression in liver of protein-restricted rats and in rat hepatoma cells limited for a single amino acid
5. Reduction of insulin-like growth factor-I (IGF-I) in protein-restricted rats is associated with differential regulation of IGF-binding protein messenger ribonucleic acids in liver and kidney, and peptides in liver and serum
6. Nutritional regulation of gene expression of insulin-like growth factor-binding proteins and the acid-labile subunit in various tissues of rats
7. An experimental study of overeating low- or high-protein diets
8. Metabolic origins of thermogenesis induced by diet
9. Characteristics of thyroid function in experimental protein malnutrition
10. Influence of diet composition on serum triiodothyronine (T3) concentration, hepatic mitochondrial metabolism and shuttle system activity in rats
11. Investigations into the etiology of elevated serum T3 levels in protein-malnourished rats
12. Mechanisms of thermogenesis induced by low protein diets
13. Dietary protein effects on lipoproteins and on sex and thyroid hormones in blood of rhesus monkeys
14. Iodothyronine 5′-deiodination in rats fed low protein diets: Lack of correlation with energy balance
15. Soybean protein suppresses hepatic lipogenic enzyme gene expression in Wistar fatty rats
16. Dietary carbohydrate and fat do not alter the thyroid response to protein deficiency in chicks
17. Gluttony and thermogenesis revisited
18. The role of dietary protein in hepatic lipogenesis in the young rat
19. Hepatic lipogenesis in young rats given proteins of different quality
20. Effects of dietary proteins on lipogenic enzymes in rat liver
21. Soybean protein suppresses hepatic lipogenic enzyme gene expression in Wistar fatty rats
22. Inhibition of aflatoxin-initiated preneoplastic liver lesions by low dietary protein
23. Effect of dietary, protein quality on development of aflatoxin B1-induced hepatic preneoplastic lesions
24. The sustained development of preneoplastic lesions depends on high protein intake
25. Inhibition of hepatocellular carcinoma development in hepatitis B virus transfected mice by low dietary casein
26. Soy and experimental cancer: Animal studies
27. Soy intake and cancer risk: A review of the in vitro and in vivo data
28. Vegan proteins may reduce risk for cancer, obesity, and cardiovascular disease by promoting increased glucagon activity
29. Dietary restriction reduces insulin-like growth factor I levels, which modulates apoptosis, cell proliferation, and tumor progression in p53-deficient mice
30. Physiological concentration of amino acids regulates insulin-like-growth-factor-binding protein I expression
31. Nutrition and somatomedin. XXIII. Molecular regulation of IGF-I by amino acid availability in cultured hepatocytes
32. ADD1/SREBP-1c is required in the activation of hepatic lipogenic gene expression by glucose
33. Sterol regulatory element-binding protein-1 as a key transcription factor for nutritional induction of lipogenic enzyme genes
34. Sterol regulatory element binding protein-1 expression is suppressed by dietary polyunsaturated fatty acids. A mechanism for the coordinate suppression of lipogenic genes by polyunsaturated fats
35. Fish oil feeding decreases mature sterol regulatory element-binding protein 1 (SREBP by down-regulation of SREBPmRNA in mouse liver: A possible mechanism for down-regulation of lipogenic enzyme mmas
36. Sterol response element-binding protein 1c (SREBP1c) is involved in the polyunsaturated fatty acid suppression of hepatic S14 gene transcription
37. In support of the roles of malonyl-CoA and carnitine acyltransferase I in the regulation of hepatic fatty acid oxidation and ketogenesis
38. Nutritionally-induced alterations in thyroid hormone metabolism and thermogenesis
39. The contribution of hepatic metabolism to diet-induced thermogenesis
40. Induction of thermogenic enzymes by DHEA and its metabolites
41. Pyruvate and hydroxycitrate/carnitine may synergize to promote reverse electron transport in hepatocyte mitochondria, effectively 'uncoupling' the oxidation of fatty acids
42. Thyroid thermogenesis in adult rat hepatocytes in primary monolayer culture: Direct action of thyroid hormone in vitro
43. Postingestional effects of a high-protein diet on the regulation of food intake in monkeys
44. Randomized trial on protein vs carbohydrate in ad libitum fat reduced diet for the treatment of obesity
45. The effect of protein intake on plasma amino acid concentrations, enzymatic activity, and food intake of rats
46. Protein and amino acids in the regulation of quantitative and qualitative aspects of food intake
47. Effect of dietary protein on serum insulin and glucagon levels in hyper-and normocholesterolemic men
48. Plasma amino acids and the insulin/glucagon ratio as an explanation for the dietary protein modulation of atherosclerosis
49. Patterns of hormonal release after glucose, protein, and glucose plus protein
50. Response of plasma insulin and growth hormone to carbohydrate and protein feeding
51. Effect of protein ingestion on the glucose and insulin response to a standardized oral glucose load
52. Ontogenesis of iodothyronine-5′-deiodinase. Induction of 5′-deiodinating activity by insulin, glucocorticoid, and thyroxine in cultured fetal mouse liver
53. Glucose and insulin reverse the effects of fasting on 3,5,3′-triiodothyronine neogenesis in primary cultures of rat hepatocytes
54. Diet and chronic degenerative diseases: Perspectives from China
55. Energy balance: Interpretation of data from rural China
56. The Oxford Vegetarian Study: An overview
57. Vegan diets and cardiovascular health
58. Preeclampsia and reproductive performance in a community of vegans