메뉴 건너뛰기




Volumn 60, Issue 2, 2003, Pages 202-208

Interleukin-2 and cancer: Critical analysis of results, problems and expectations

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; GROWTH FACTOR; INTERLEUKIN 2; MONOCLONAL ANTIBODY;

EID: 0037320981     PISSN: 03069877     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-9877(02)00359-6     Document Type: Article
Times cited : (5)

References (96)
  • 1
    • 0014887939 scopus 로고
    • The concept of immunological surveillance
    • Burnet M. F. The concept of immunological surveillance. Prog Exp Tumor Res 1970; 13: 1-27.
    • (1970) Prog Exp Tumor Res , vol.13 , pp. 1-27
    • Burnet, M.F.1
  • 2
    • 0033916260 scopus 로고    scopus 로고
    • Strategies for immunotherapy of cancer
    • Cornelis J. M., Offringa R. Strategies for immunotherapy of cancer. Adv Immunol 2000; 75: 235-282.
    • (2000) Adv Immunol , vol.75 , pp. 235-282
    • Cornelis, J.M.1    Offringa, R.2
  • 3
    • 0013237863 scopus 로고    scopus 로고
    • Malignancy after renal transplantation: Analysis of incidence and risk factors in 1700 patients followed during a 25 year period
    • Hiesse C., Charpentier B. Malignancy after renal transplantation: analysis of incidence and risk factors in 1700 patients followed during a 25 year period. Transplant Proc 1997; 71: 517-520.
    • (1997) Transplant Proc , vol.71 , pp. 517-520
    • Hiesse, C.1    Charpentier, B.2
  • 4
    • 16044368963 scopus 로고    scopus 로고
    • KSHV antibodies among Americans, Italians and Ugendants with and without Kaposis's sarcoma
    • Gao S. J., Moore P. S. KSHV antibodies among Americans, Italians and Ugendants with and without Kaposis's sarcoma. Nature 1996; 2: 925-929.
    • (1996) Nature , vol.2 , pp. 925-929
    • Gao, S.J.1    Moore, P.S.2
  • 5
    • 0023851773 scopus 로고
    • Acute local inflammation causing generalized increased ground substance viscosity: Guttate psoriasis, Reiter's syndrome, adjuvant disease, cancer regression
    • Stone O. J. Acute local inflammation causing generalized increased ground substance viscosity: guttate psoriasis, Reiter's syndrome, adjuvant disease, cancer regression. Med Hypotheses 1988; 25: 141-145.
    • (1988) Med Hypotheses , vol.25 , pp. 141-145
    • Stone, O.J.1
  • 6
    • 0029024279 scopus 로고
    • Tumorigenesis and metastasis of neoplastic Kaposis's sarcoma cell line in immunodeficient mice blocked by a human pregnancy hormone
    • Lunardi-Iskandar Y., Gallo R. C. Tumorigenesis and metastasis of neoplastic Kaposis's sarcoma cell line in immunodeficient mice blocked by a human pregnancy hormone. Nature 1995; 375: 64-68.
    • (1995) Nature , vol.375 , pp. 64-68
    • Lunardi-Iskandar, Y.1    Gallo, R.C.2
  • 7
    • 0001322471 scopus 로고
    • Further observations upon the treatment of malignant tumors with the toxins of erysipelas and Bacillus Prodigious with a report of 160 cases
    • Coley W. B. Further observations upon the treatment of malignant tumors with the toxins of erysipelas and Bacillus Prodigious with a report of 160 cases. Bull John Hopkins Hosp 1896; 7: 157.
    • (1896) Bull John Hopkins Hosp , vol.7 , pp. 157
    • Coley, W.B.1
  • 8
    • 0014664421 scopus 로고
    • Active immunotherapy for acute lymphoblastic leukemia
    • Mathe G., Schwarzenberg L. Active immunotherapy for acute lymphoblastic leukemia. Lancet 1969; 1: 697-699.
    • (1969) Lancet , vol.1 , pp. 697-699
    • Mathe, G.1    Schwarzenberg, L.2
  • 9
    • 0014013889 scopus 로고
    • Attempts adoptive immunotherapy of acute leukemia by leukocyte transfusions
    • Schwarzenberg L., Schneider M. Attempts adoptive immunotherapy of acute leukemia by leukocyte transfusions. Lancet 1966; 2: 365-368.
    • (1966) Lancet , vol.2 , pp. 365-368
    • Schwarzenberg, L.1    Schneider, M.2
  • 10
    • 0026792806 scopus 로고
    • Role of the immune response in BCG bladder cancer
    • Ratliff T. L. Role of the immune response in BCG bladder cancer. Eur Urol 1992; 21(Suppl. 21): 17-21.
    • (1992) Eur Urol , vol.21 , Issue.SUPPL. 21 , pp. 17-21
    • Ratliff, T.L.1
  • 11
    • 0023775236 scopus 로고
    • Therapy of patients with human T cell lymphotropic virus I induced T cell leukemia with anti-Tac, a monoclonal antibody to the receptor for interleukin 2
    • Waldmann T. A. Therapy of patients with human T cell lymphotropic virus I induced T cell leukemia with anti-Tac, a monoclonal antibody to the receptor for interleukin 2. Blood 1986; 72: 1805-1816.
    • (1986) Blood , vol.72 , pp. 1805-1816
    • Waldmann, T.A.1
  • 13
    • 0032425063 scopus 로고    scopus 로고
    • Tumor immunology: The glass is half full
    • Sogn J. A. Tumor immunology: the glass is half full. Immunity 1998; 9: 757-763.
    • (1998) Immunity , vol.9 , pp. 757-763
    • Sogn, J.A.1
  • 14
    • 0017199306 scopus 로고
    • Selective in vitro growth of T lymphocytes from normal bone marrow
    • Morgan D. A., Gallo R. C. Selective in vitro growth of T lymphocytes from normal bone marrow. Science 1976; 193: 1007-1008.
    • (1976) Science , vol.193 , pp. 1007-1008
    • Morgan, D.A.1    Gallo, R.C.2
  • 15
    • 0020699991 scopus 로고
    • Structure and expression of a cloned cDNA for human interleukin 2
    • Taniguchi T., Fujita T. Structure and expression of a cloned cDNA for human interleukin 2. Nature 1983; 302: 305-307.
    • (1983) Nature , vol.302 , pp. 305-307
    • Taniguchi, T.1    Fujita, T.2
  • 16
    • 0033491981 scopus 로고    scopus 로고
    • Biology of the interleukin 2 receptor
    • Nelson B. H., Willerford D. M. Biology of the interleukin 2 receptor. Adv Immunol 1998; 70: 1-81.
    • (1998) Adv Immunol , vol.70 , pp. 1-81
    • Nelson, B.H.1    Willerford, D.M.2
  • 17
    • 0026017971 scopus 로고
    • Interleukin 2 programs mouse αβ T lymphocytes for apoptosis
    • Lenardo M. Interleukin 2 programs mouse αβ T lymphocytes for apoptosis. Nature 1991; 353: 858-861.
    • (1991) Nature , vol.353 , pp. 858-861
    • Lenardo, M.1
  • 18
    • 17544398702 scopus 로고    scopus 로고
    • Biochemical mechanisms of IL-2 regulated Fas mediated T cell apoptosis
    • Rafaeli Y., Abbas A. K. Biochemical mechanisms of IL-2 regulated Fas mediated T cell apoptosis. Immunity 1998; 8: 615-623.
    • (1998) Immunity , vol.8 , pp. 615-623
    • Rafaeli, Y.1    Abbas, A.K.2
  • 19
    • 0019951384 scopus 로고
    • The lymphokine activated killer cell phenomenon: Lysis of NK resistant fresh solid tumor cells by IL-2 activated autologous human peripheral blood lymphocytes
    • Grimm E. A., Rosenberg S. A. The lymphokine activated killer cell phenomenon: lysis of NK resistant fresh solid tumor cells by IL-2 activated autologous human peripheral blood lymphocytes. J Exp Med 1982; 155: 1823-1841.
    • (1982) J Exp Med , vol.155 , pp. 1823-1841
    • Grimm, E.A.1    Rosenberg, S.A.2
  • 20
    • 0021917804 scopus 로고
    • Lymphokine activated killer (LAK) cells, analysis of effectors relevant to the immunotherapy of human cancer
    • Rayner A. A., Lotze M. T. Lymphokine activated killer (LAK) cells, analysis of effectors relevant to the immunotherapy of human cancer. Cancer 1985; 55: 1327-1333.
    • (1985) Cancer , vol.55 , pp. 1327-1333
    • Rayner, A.A.1    Lotze, M.T.2
  • 21
    • 0022501035 scopus 로고
    • Lymphokine activated killer cells: Analysis of progenitors and effectors
    • Ortaldo J. R., Overton R. Lymphokine activated killer cells: analysis of progenitors and effectors. J Exp Med 1986; 164: 1193-1205.
    • (1986) J Exp Med , vol.164 , pp. 1193-1205
    • Ortaldo, J.R.1    Overton, R.2
  • 22
    • 0023093741 scopus 로고
    • Identification of specific cytolytic immune responses against autologous tumor in humans bearing malignant melanoma
    • Muul L. M., Director E. P. Identification of specific cytolytic immune responses against autologous tumor in humans bearing malignant melanoma. J Immunol 1987; 138: 989-995.
    • (1987) J Immunol , vol.138 , pp. 989-995
    • Muul, L.M.1    Director, E.P.2
  • 23
    • 0022446727 scopus 로고
    • Interleukin 2 activation of cytolytic T lymphocytes infiltrating into human metastatic melanoma
    • Itoh K., Balchs C. M. Interleukin 2 activation of cytolytic T lymphocytes infiltrating into human metastatic melanoma. Cancer Res 1986; 46: 3011-3017.
    • (1986) Cancer Res , vol.46 , pp. 3011-3017
    • Itoh, K.1    Balchs, C.M.2
  • 24
    • 0020586786 scopus 로고
    • The fate of interleukin 2 after in vivo administration
    • Donoline J. H., Rosenberg S. A. The fate of interleukin 2 after in vivo administration. J Immunol 1983; 130: 2203-2208.
    • (1983) J Immunol , vol.130 , pp. 2203-2208
    • Donoline, J.H.1    Rosenberg, S.A.2
  • 25
    • 0021219746 scopus 로고
    • Systemic administration of recombinant IL-2 in mice
    • Chang A. E., Rosenberg S. A. Systemic administration of recombinant IL-2 in mice. J Biol Response Mod 1984; 3: 561-6572.
    • (1984) J Biol Response Mod , vol.3 , pp. 561-6572
    • Chang, A.E.1    Rosenberg, S.A.2
  • 26
    • 0021837706 scopus 로고
    • Regression of established pulmonary metastases and subcutaneous tumor mediated by the systemic administration of high dose recombinant interleukin 2
    • Rosenberg, Schwarz S. Regression of established pulmonary metastases and subcutaneous tumor mediated by the systemic administration of high dose recombinant interleukin 2. J Exp Med 1985; 161: 1169-1188.
    • (1985) J Exp Med , vol.161 , pp. 1169-1188
    • Rosenberg1    Schwarz, S.2
  • 27
    • 0021346649 scopus 로고
    • Successful immunotherapy of natural killer resistant established pulmonary melanoma metastases by the intravenous adoptive transfer of syngenic lymphocytes activated in vitro by interleukin 2
    • Mazumder A., Rosenberg S. A. Successful immunotherapy of natural killer resistant established pulmonary melanoma metastases by the intravenous adoptive transfer of syngenic lymphocytes activated in vitro by interleukin 2. J Exp Med 1984; 159: 495-507.
    • (1984) J Exp Med , vol.159 , pp. 495-507
    • Mazumder, A.1    Rosenberg, S.A.2
  • 28
    • 0023034337 scopus 로고
    • Immunotherapy of murine sarcomas with interleukin 2. I. Local administration of human recombinant IL-2 preparation
    • Bubenick J., Toulcova A. Immunotherapy of murine sarcomas with interleukin 2. I. Local administration of human recombinant IL-2 preparation. Folia Biol (Praha) 1986; 32: 384-391.
    • (1986) Folia Biol (Praha) , vol.32 , pp. 384-391
    • Bubenick, J.1    Toulcova, A.2
  • 29
    • 0023224937 scopus 로고
    • Local and systemic effects during interleukin 2 therapy of mouse mammary tumors
    • Vaage J. Local and systemic effects during interleukin 2 therapy of mouse mammary tumors. Cancer Res 1987; 47: 4296-4298.
    • (1987) Cancer Res , vol.47 , pp. 4296-4298
    • Vaage, J.1
  • 30
    • 0022524969 scopus 로고
    • Inhibition of tumor growth in a mouse fibrosarcoma after interleukin 2 application
    • Barbery H., Schwulera U. Inhibition of tumor growth in a mouse fibrosarcoma after interleukin 2 application. Immunobiology 1986; 172: 383-390.
    • (1986) Immunobiology , vol.172 , pp. 383-390
    • Barbery, H.1    Schwulera, U.2
  • 31
    • 0029804782 scopus 로고    scopus 로고
    • Decreased tumor surveillance in perforin deficient mice
    • Van Der Broek M., Hengartner H. Decreased tumor surveillance in perforin deficient mice. J Exp Med 1996; 184: 1781-1790.
    • (1996) J Exp Med , vol.184 , pp. 1781-1790
    • Van Der Broek, M.1    Hengartner, H.2
  • 32
    • 0028219791 scopus 로고
    • Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin deficient mice
    • Kagi D., Hengartner H. Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin deficient mice. Nature 1994; 369: 31-37.
    • (1994) Nature , vol.369 , pp. 31-37
    • Kagi, D.1    Hengartner, H.2
  • 33
    • 0034605122 scopus 로고    scopus 로고
    • Perforin mediated cytotoxicity is critical for surveillance of spontaneous lymphoma
    • Smyth M. J., Trapain J. A. Perforin mediated cytotoxicity is critical for surveillance of spontaneous lymphoma. J Exp Med 2000; 192: 755-760.
    • (2000) J Exp Med , vol.192 , pp. 755-760
    • Smyth, M.J.1    Trapain, J.A.2
  • 34
    • 0033152840 scopus 로고    scopus 로고
    • Perforin is major contributor to NK cell control of tumor metastasis
    • Smyth M. J., Scalzo A. A. Perforin is major contributor to NK cell control of tumor metastasis. J Immunol 1999; 162: 6658-6662.
    • (1999) J Immunol , vol.162 , pp. 6658-6662
    • Smyth, M.J.1    Scalzo, A.A.2
  • 35
    • 0023115642 scopus 로고
    • A progress report on the treatment of 157 patients with advanced cancer using activated killer cells and interleukin 2 or high dose interleukin 2 alone
    • Rosenberg S. A., White D. E. A progress report on the treatment of 157 patients with advanced cancer using activated killer cells and interleukin 2 or high dose interleukin 2 alone. N Eng J Med 1987; 316: 889-897.
    • (1987) N Eng J Med , vol.316 , pp. 889-897
    • Rosenberg, S.A.1    White, D.E.2
  • 36
    • 85004967193 scopus 로고
    • Metastatic renal cell carcinoma treated with IL-2 and lymphokine activated killer cells. A phase I trial
    • Fischer R. I., Paietta E. Metastatic renal cell carcinoma treated with IL-2 and lymphokine activated killer cells. A phase I trial. Ann Inter Med 1988; 108: 518-523.
    • (1988) Ann Inter Med , vol.108 , pp. 518-523
    • Fischer, R.I.1    Paietta, E.2
  • 37
    • 0024426282 scopus 로고
    • Interleukin 2 with and without LAK cells in metastatic renal cell carcinoma: The Lyon first year experience on 20 patients
    • Philip T., Clavel M. Interleukin 2 with and without LAK cells in metastatic renal cell carcinoma: the Lyon first year experience on 20 patients. Cancer Treat Rev 1989; 16(Suppl. A): 91-104.
    • (1989) Cancer Treat Rev , vol.16 , Issue.SUPPL. A , pp. 91-104
    • Philip, T.1    Clavel, M.2
  • 38
    • 0034666385 scopus 로고    scopus 로고
    • Cytokines in cancer therapy
    • Parmiani G., Carrabla M. Cytokines in cancer therapy. Immunol Lett 2000; 74: 41-42.
    • (2000) Immunol Lett , vol.74 , pp. 41-42
    • Parmiani, G.1    Carrabla, M.2
  • 39
    • 0030981706 scopus 로고    scopus 로고
    • The host tumor immune conflict: From immunosuppression to resistance and destruction
    • Chouaib S., Blay J. Y. The host tumor immune conflict: from immunosuppression to resistance and destruction. Immunol Today 1997.
    • (1997) Immunol Today
    • Chouaib, S.1    Blay, J.Y.2
  • 40
    • 0023123517 scopus 로고
    • Constant infusion recombinant interleukin 2 in adoptive immunotherapy and advanced cancer
    • West W. H., Oldhan R. K. Constant infusion recombinant interleukin 2 in adoptive immunotherapy and advanced cancer. N Eng J Med 1987; 316: 898-905.
    • (1987) N Eng J Med , vol.316 , pp. 898-905
    • West, W.H.1    Oldhan, R.K.2
  • 41
    • 14744306403 scopus 로고
    • Rational immunotherapy with interleukin 2
    • Kaplan G., Smith K. A. Rational immunotherapy with interleukin 2. Biotechnology 1992; 10: 157-162.
    • (1992) Biotechnology , vol.10 , pp. 157-162
    • Kaplan, G.1    Smith, K.A.2
  • 42
    • 0024206262 scopus 로고
    • Treatment of recurrent squamous cell carcinoma of head and neck with low dose of interleukin 2 (IL-2) injected perilymphatically
    • Cortesina G., Forni G. Treatment of recurrent squamous cell carcinoma of head and neck with low dose of interleukin 2 (IL-2) injected perilymphatically. Cancer (Phila) 1988; 62: 2482-2485.
    • (1988) Cancer (Phila) , vol.62 , pp. 2482-2485
    • Cortesina, G.1    Forni, G.2
  • 43
    • 0028846205 scopus 로고
    • Intrapleural administration of interleukin 2 in pleural mesothelioma: A phase I-II study
    • Goey S. H., Stoter G. Intrapleural administration of interleukin 2 in pleural mesothelioma: a phase I-II study. Br J Cancer 1995; 72: 1283-1288.
    • (1995) Br J Cancer , vol.72 , pp. 1283-1288
    • Goey, S.H.1    Stoter, G.2
  • 44
    • 0024583825 scopus 로고
    • The reconstitution of cell mediated immunity in the cutaneous lesions of lepromatous leprosy by recombinant interleukin 2
    • Kaplan G., Cohn Z. A. The reconstitution of cell mediated immunity in the cutaneous lesions of lepromatous leprosy by recombinant interleukin 2. J Exp Med 1989; 169: 893-907.
    • (1989) J Exp Med , vol.169 , pp. 893-907
    • Kaplan, G.1    Cohn, Z.A.2
  • 45
    • 0032520908 scopus 로고    scopus 로고
    • Ultra low dose interleukin 2 therapy promotes a type 1 cytokine profile in vivo in patients with AIDS and AIDS associated malignancies
    • Khatri V. P. Ultra low dose interleukin 2 therapy promotes a type 1 cytokine profile in vivo in patients with AIDS and AIDS associated malignancies. J Clin Invest 1998; 101: 1373-1378.
    • (1998) J Clin Invest , vol.101 , pp. 1373-1378
    • Khatri, V.P.1
  • 46
    • 0343046852 scopus 로고
    • Recombinant interleukin 2 therapy in severe combined immunodeficiency diseases
    • Pahwa R., Good R. A. Recombinant interleukin 2 therapy in severe combined immunodeficiency diseases. Proc Natl Acad Sci USA 1989; 86: 5069-5073.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 5069-5073
    • Pahwa, R.1    Good, R.A.2
  • 47
    • 0025095664 scopus 로고
    • Interleukin 2 production by tumor cells bypasses T helper function in the generation of an antitumor response
    • Fearon E. R., Frost P. Interleukin 2 production by tumor cells bypasses T helper function in the generation of an antitumor response. Cell 1990; 60: 397-403.
    • (1990) Cell , vol.60 , pp. 397-403
    • Fearon, E.R.1    Frost, P.2
  • 48
    • 0030714556 scopus 로고    scopus 로고
    • Immunotherapy I: Cytokine gene transfer strategies
    • Colombo M. P., Forni G. Immunotherapy I: cytokine gene transfer strategies. Cancer Metastais Rev 1997; 16: 421-432.
    • (1997) Cancer Metastais Rev , vol.16 , pp. 421-432
    • Colombo, M.P.1    Forni, G.2
  • 49
    • 0026728912 scopus 로고
    • Expression of the interleukin 2 receptor on human fibroblasts and its biological significance
    • Plaisance S., Azzarone B. Expression of the interleukin 2 receptor on human fibroblasts and its biological significance. Int Immunol 1992; 4: 739-746.
    • (1992) Int Immunol , vol.4 , pp. 739-746
    • Plaisance, S.1    Azzarone, B.2
  • 50
    • 0027257928 scopus 로고
    • The IL-2 receptor present on human embryonic fibroblasts is functional in the absence of p64/IL-2Rγ
    • Plaisance S., Azzarone B. The IL-2 receptor present on human embryonic fibroblasts is functional in the absence of p64/IL-2Rγ. Int Immunol 1993; 5: 843-848.
    • (1993) Int Immunol , vol.5 , pp. 843-848
    • Plaisance, S.1    Azzarone, B.2
  • 51
    • 0025995614 scopus 로고
    • Investigation of interleukin 2 receptors on human endothelial cells
    • Hicks C., Penny R. Investigation of interleukin 2 receptors on human endothelial cells. Growth Factors 1991; 5: 201-208.
    • (1991) Growth Factors , vol.5 , pp. 201-208
    • Hicks, C.1    Penny, R.2
  • 52
    • 0024246216 scopus 로고
    • Influence of natural and recombinant IL-2 on endothelial cell arachidonate metabolism. Induction of de novo synthesis of Prostaglandin H synthase
    • Frasier S. K., Wu K. Influence of natural and recombinant IL-2 on endothelial cell arachidonate metabolism. Induction of de novo synthesis of Prostaglandin H synthase. J Clin Invest 1988; 82: 1877-1883.
    • (1988) J Clin Invest , vol.82 , pp. 1877-1883
    • Frasier, S.K.1    Wu, K.2
  • 53
    • 0022446998 scopus 로고
    • Stimulation of oligodendroglial cell proliferation and maturation by IL-2
    • Benveniste E. N., Merrill J. E. Stimulation of oligodendroglial cell proliferation and maturation by IL-2. Nature 1986; 321: 610-613.
    • (1986) Nature , vol.321 , pp. 610-613
    • Benveniste, E.N.1    Merrill, J.E.2
  • 54
    • 0026707969 scopus 로고
    • Diseases associated with HTLV-I: Virus, IL-2 receptor dysregulation and redox regulation
    • Yodoi J., Uchiyama T. Diseases associated with HTLV-I: virus, IL-2 receptor dysregulation and redox regulation. Immunol Today 1992; 13: 405-411.
    • (1992) Immunol Today , vol.13 , pp. 405-411
    • Yodoi, J.1    Uchiyama, T.2
  • 55
    • 0027303339 scopus 로고
    • Expression of IL-2 receptor in human melanoma cells
    • Rimoldi D., Carrel S. Expression of IL-2 receptor in human melanoma cells. Anticancer Res 1993; 13: 555-564.
    • (1993) Anticancer Res , vol.13 , pp. 555-564
    • Rimoldi, D.1    Carrel, S.2
  • 56
    • 0027327614 scopus 로고
    • Human melanoma cells express a functional interleukin 2 receptor
    • Plaisance S., Azzarone B. Human melanoma cells express a functional interleukin 2 receptor. Int J Cancer 1993; 55: 164-170.
    • (1993) Int J Cancer , vol.55 , pp. 164-170
    • Plaisance, S.1    Azzarone, B.2
  • 57
    • 0026354055 scopus 로고
    • Isolation and characterization of human melanoma cell variants expressing high and low level of CD 44
    • Birch M., Hart I. R. Isolation and characterization of human melanoma cell variants expressing high and low level of CD 44. Cancer Res 1991; 51: 6660-6667.
    • (1991) Cancer Res , vol.51 , pp. 6660-6667
    • Birch, M.1    Hart, I.R.2
  • 58
    • 0027186140 scopus 로고
    • Human melanoma cell line M14 secretes a functional interleukin 2
    • Alileche A., Azzarone B. Human melanoma cell line M14 secretes a functional interleukin 2. Oncogene 1993; 8: 1791-1796.
    • (1993) Oncogene , vol.8 , pp. 1791-1796
    • Alileche, A.1    Azzarone, B.2
  • 59
    • 9844258329 scopus 로고    scopus 로고
    • Role of interleuktn 2 and IL-15 in the tumor progression of a melanoma cell line MELP derived from an IL-2 progressor patient
    • Doucet C., Azzarone B. Role of interleuktn 2 and IL-15 in the tumor progression of a melanoma cell line MELP derived from an IL-2 progressor patient. Melanoma Res 1997; 7(Suppl. 2): S7-S17.
    • (1997) Melanoma Res , vol.7 , Issue.SUPPL. 2
    • Doucet, C.1    Azzarone, B.2
  • 60
    • 0029007229 scopus 로고
    • The addition on interleukin 2 and cyclophosphamide therapy can facilitate tumor growth of B16 melanoma
    • Polamares T., Guillem E. B. The addition on interleukin 2 and cyclophosphamide therapy can facilitate tumor growth of B16 melanoma. Cancer Immunol Immunolther 1995; 40: 292-298.
    • (1995) Cancer Immunol Immunolther , vol.40 , pp. 292-298
    • Polamares, T.1    Guillem, E.B.2
  • 61
    • 0026485322 scopus 로고
    • Receptors on human squamous cell carcinoma cell lines and tumor in situ
    • Weidman E., Whiteside T. L. Receptors on human squamous cell carcinoma cell lines and tumor in situ. Cancer Res 1992; 52: 5963-5970.
    • (1992) Cancer Res , vol.52 , pp. 5963-5970
    • Weidman, E.1    Whiteside, T.L.2
  • 62
    • 0025351950 scopus 로고
    • Local adoptive immunotherapy of human head and neck cancer xenograffs in nude mice with lymphokine activated killer cells and interleukin 2
    • Sacchi M., Whiteside T. L. Local adoptive immunotherapy of human head and neck cancer xenograffs in nude mice with lymphokine activated killer cells and interleukin 2. Cancer Res 1990; 50: 3113-3118.
    • (1990) Cancer Res , vol.50 , pp. 3113-3118
    • Sacchi, M.1    Whiteside, T.L.2
  • 63
    • 0025818703 scopus 로고
    • Induction of tumor regression in experimental model of human head and neck cancer by human A-LAK cells and IL-2
    • Sacchi M., Whiteside T. L. Induction of tumor regression in experimental model of human head and neck cancer by human A-LAK cells and IL-2. Int J Cancer 1991; 47: 784-791.
    • (1991) Int J Cancer , vol.47 , pp. 784-791
    • Sacchi, M.1    Whiteside, T.L.2
  • 64
    • 0034719334 scopus 로고    scopus 로고
    • Interleukin 2 expression in human carcinoma cell lines and its role in cell cycle progression
    • Reichert T. E., Whiteside T. L. Interleukin 2 expression in human carcinoma cell lines and its role in cell cycle progression. Oncogene 2000; 19: 514-525.
    • (2000) Oncogene , vol.19 , pp. 514-525
    • Reichert, T.E.1    Whiteside, T.L.2
  • 65
    • 0033846746 scopus 로고    scopus 로고
    • Interleukin 2 induces cell cycle perturbations leading to cell growth inhibition and death in malignant mesothelioma cells in vitro
    • Porta C., Mutti L. Interleukin 2 induces cell cycle perturbations leading to cell growth inhibition and death in malignant mesothelioma cells in vitro. J Cell Physiol 2000; 185: 126-134.
    • (2000) J Cell Physiol , vol.185 , pp. 126-134
    • Porta, C.1    Mutti, L.2
  • 66
    • 0032533285 scopus 로고    scopus 로고
    • Intrapleural administration of interleukin 2 for the treatment of patients with malignant pleural mesothelioma. A phase II study
    • Astoul P., Boutin C. Intrapleural administration of interleukin 2 for the treatment of patients with malignant pleural mesothelioma. A phase II study. Cancer 1998; 83: 2099-2104.
    • (1998) Cancer , vol.83 , pp. 2099-2104
    • Astoul, P.1    Boutin, C.2
  • 67
    • 0026742426 scopus 로고
    • Intracavitary administration of interleukin 2 as aplliative therapy for neoplastic effusions
    • Lissoni P., Tancini G. Intracavitary administration of interleukin 2 as aplliative therapy for neoplastic effusions. Tumori 1992; 78: 118-120.
    • (1992) Tumori , vol.78 , pp. 118-120
    • Lissoni, P.1    Tancini, G.2
  • 68
    • 0028051707 scopus 로고
    • Expression of interleukin 2 receptors on human carcinoma cell lines and tumor inhibition by interleukin 2
    • Yasumura S., Whiteside T. L. Expression of interleukin 2 receptors on human carcinoma cell lines and tumor inhibition by interleukin 2. Int J Cancer 1994; 59: 225-234.
    • (1994) Int J Cancer , vol.59 , pp. 225-234
    • Yasumura, S.1    Whiteside, T.L.2
  • 69
    • 0024242277 scopus 로고
    • Interleukin 2 differntially affects the proliferation of a hormone dependent and a hormone independent human breast cancer cell line in vitro and in vivo
    • Paciotti G. F., Tamarkin L. Interleukin 2 differntially affects the proliferation of a hormone dependent and a hormone independent human breast cancer cell line in vitro and in vivo. Anticancer Res 1988; 8: 1233-1239.
    • (1988) Anticancer Res , vol.8 , pp. 1233-1239
    • Paciotti, G.F.1    Tamarkin, L.2
  • 70
    • 0033805413 scopus 로고    scopus 로고
    • IL-2, its receptors, and bcl-2 and bax genes in normal, hyperplastic and carcinomatous human prostates: Immunohistochemical comparative analysis
    • Royula M., Paniagua R. IL-2, its receptors, and bcl-2 and bax genes in normal, hyperplastic and carcinomatous human prostates: immunohistochemical comparative analysis. Growth Factors 2000; 18: 135-146.
    • (2000) Growth Factors , vol.18 , pp. 135-146
    • Royula, M.1    Paniagua, R.2
  • 71
    • 0033514923 scopus 로고    scopus 로고
    • Immune surveillance against a solid tumor fails because of immunological surveillance
    • Ochsenbein A. F., Zinkernagel R. M. Immune surveillance against a solid tumor fails because of immunological surveillance. Proc Natl Acad Sci USA 1999; 96: 2233-2238.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 2233-2238
    • Ochsenbein, A.F.1    Zinkernagel, R.M.2
  • 72
    • 0030576517 scopus 로고    scopus 로고
    • Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
    • Hanahan D., Folkman J. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 1996; 86: 353-364.
    • (1996) Cell , vol.86 , pp. 353-364
    • Hanahan, D.1    Folkman, J.2
  • 73
    • 0028928899 scopus 로고
    • Inhibition of tumor growth by elimination of granulocytes
    • Pekarek L. A., Schreiber H. Inhibition of tumor growth by elimination of granulocytes. J Exp Med 1995; 181: 435-440.
    • (1995) J Exp Med , vol.181 , pp. 435-440
    • Pekarek, L.A.1    Schreiber, H.2
  • 74
    • 0030922493 scopus 로고    scopus 로고
    • Mast cell tumor cell interaction: For or against tumor growth and metastasis
    • Dimitriadou V., Koutsilieris M. Mast cell tumor cell interaction: for or against tumor growth and metastasis. Anticancer Res 1997; 17: 1541-1550.
    • (1997) Anticancer Res , vol.17 , pp. 1541-1550
    • Dimitriadou, V.1    Koutsilieris, M.2
  • 75
    • 0030998660 scopus 로고    scopus 로고
    • Macrophage derived metalloelastase is responsible for the generation of angiostatin in Lewis lung carcinoma
    • Dong Z., Fidler I. J. Macrophage derived metalloelastase is responsible for the generation of angiostatin in Lewis lung carcinoma. Cell 1997; 88: 801-810.
    • (1997) Cell , vol.88 , pp. 801-810
    • Dong, Z.1    Fidler, I.J.2
  • 76
    • 0029784242 scopus 로고    scopus 로고
    • New insights into tumor host interaction in lymphocyte metastasis
    • Umansky V., Rocha M. New insights into tumor host interaction in lymphocyte metastasis. J Mol Med 1996; 74: 353-363.
    • (1996) J Mol Med , vol.74 , pp. 353-363
    • Umansky, V.1    Rocha, M.2
  • 77
    • 0033993449 scopus 로고    scopus 로고
    • Tumor counterattack, concept and reality
    • Igney F. H., Krammer P. H. Tumor counterattack, concept and reality. Eur J Immunol 2000; 30: 725-731.
    • (2000) Eur J Immunol , vol.30 , pp. 725-731
    • Igney, F.H.1    Krammer, P.H.2
  • 78
    • 85080850204 scopus 로고    scopus 로고
    • Eosinophils and serum eosinophils cationic proteins in interleukin 2 based immunotherapy of cancer
    • Porta C., De Amici M. Eosinophils and serum eosinophils cationic proteins in interleukin 2 based immunotherapy of cancer. Br J Heamatol 1998; 100: 607-608.
    • (1998) Br J Heamatol , vol.100 , pp. 607-608
    • Porta, C.1    De Amici, M.2
  • 79
    • 0023833136 scopus 로고
    • Effect of shistosoma mansoni and cyclophosphamide on a mouse fibrosarcoma
    • Laures M. A. Effect of shistosoma mansoni and cyclophosphamide on a mouse fibrosarcoma. Braz J Med Biol Res 1988; 21: 93-96.
    • (1988) Braz J Med Biol Res , vol.21 , pp. 93-96
    • Laures, M.A.1
  • 80
    • 0022891340 scopus 로고
    • Tumors: Wounds that do not heal
    • Dvorak H. F. Tumors: wounds that do not heal. N Eng J Med 1986; 315: 1650-1659.
    • (1986) N Eng J Med , vol.315 , pp. 1650-1659
    • Dvorak, H.F.1
  • 81
    • 0023718895 scopus 로고
    • Stromal involvement in malignant growth
    • Van Den Hooff A. Stromal involvement in malignant growth. Adv Cancer Res 1988; 50: 159-196.
    • (1988) Adv Cancer Res , vol.50 , pp. 159-196
    • Van Den Hooff, A.1
  • 82
    • 0021714105 scopus 로고
    • Tumor invasion and metastasis: Role of basement membrane
    • Liotta L. A. Tumor invasion and metastasis: role of basement membrane. Am J Pathol 1984; 117: 339-384.
    • (1984) Am J Pathol , vol.117 , pp. 339-384
    • Liotta, L.A.1
  • 83
    • 0026547421 scopus 로고
    • Stroma is critical for preventing or permitting immunological destruction of antigen cancer cells
    • Singh S., Screiber H. Stroma is critical for preventing or permitting immunological destruction of antigen cancer cells. J Exp Med 1992; 175: 139-146.
    • (1992) J Exp Med , vol.175 , pp. 139-146
    • Singh, S.1    Screiber, H.2
  • 84
    • 0025103317 scopus 로고
    • Fibroblast mediated acceleration of human epithelial tumor growth in vivo
    • Camps J. L., Chung L. W. K. Fibroblast mediated acceleration of human epithelial tumor growth in vivo. Proc Natl Acad Sci USA 1990; 87: 75-79.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 75-79
    • Camps, J.L.1    Chung, L.W.K.2
  • 85
    • 0029563126 scopus 로고
    • The role of fibroblasts in tumor behavior
    • Gregoire M., Lieubeau B. The role of fibroblasts in tumor behavior. Cancer Metastasis Rev 1995; 14: 339-350.
    • (1995) Cancer Metastasis Rev , vol.14 , pp. 339-350
    • Gregoire, M.1    Lieubeau, B.2
  • 86
    • 0022646948 scopus 로고
    • Fibroblast dependent tumorigenicity of cells in nude mice: Implication for implantation of metastases
    • Picard O., Poupon M. F. Fibroblast dependent tumorigenicity of cells in nude mice: implication for implantation of metastases. Cancer Res 1986; 46: 3290-3294.
    • (1986) Cancer Res , vol.46 , pp. 3290-3294
    • Picard, O.1    Poupon, M.F.2
  • 87
    • 0032544686 scopus 로고    scopus 로고
    • Tumor induction of VGEF promoter activity in stromal cells
    • Fukumura D., Seed B. Tumor induction of VGEF promoter activity in stromal cells. Cell 1998; 94: 715-725.
    • (1998) Cell , vol.94 , pp. 715-725
    • Fukumura, D.1    Seed, B.2
  • 88
    • 0015311426 scopus 로고
    • Antiangiogenesis: New concepts for therapy of solid tumors
    • Folkman J. Antiangiogenesis: new concepts for therapy of solid tumors. Ann Surg 1972; 175: 409-416.
    • (1972) Ann Surg , vol.175 , pp. 409-416
    • Folkman, J.1
  • 89
    • 0025868178 scopus 로고
    • Fibroblast cell interaction with human melanoma cells affect tumor cell growth as a function of tumor progression
    • Cornil I., Kerbel R. S. Fibroblast cell interaction with human melanoma cells affect tumor cell growth as a function of tumor progression. Proc Natl Acad Sci USA 1991; 88: 6028-6032.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 6028-6032
    • Cornil, I.1    Kerbel, R.S.2
  • 90
    • 0027396955 scopus 로고
    • Interleukin 6 undergoes transition from paracrine growth inhibitor to autocrine stimulation during human melanoma progression
    • Lu C., Kerbel R. S. Interleukin 6 undergoes transition from paracrine growth inhibitor to autocrine stimulation during human melanoma progression. J Cell Biol 1993; 120: 1281-1288.
    • (1993) J Cell Biol , vol.120 , pp. 1281-1288
    • Lu, C.1    Kerbel, R.S.2
  • 91
    • 0026625812 scopus 로고
    • Serum level of interleukin 6 as a prognosis in metastatic renal cell carcinoma
    • Blay J. Y., Philip T. Serum level of interleukin 6 as a prognosis in metastatic renal cell carcinoma. Cancer Res 1992; 52: 3317-3322.
    • (1992) Cancer Res , vol.52 , pp. 3317-3322
    • Blay, J.Y.1    Philip, T.2
  • 92
    • 0023183685 scopus 로고
    • An immunohistological study of cells infiltrating progressive and regressive tumors induced bu two variants subpopulation of a rat colon cancer cell line
    • Martin M. S., Martin F. An immunohistological study of cells infiltrating progressive and regressive tumors induced bu two variants subpopulation of a rat colon cancer cell line. Int J Cancer 1987; 40: 87-93.
    • (1987) Int J Cancer , vol.40 , pp. 87-93
    • Martin, M.S.1    Martin, F.2
  • 93
    • 0028609789 scopus 로고
    • The role of transforming growth factor β1 in the fibroblastic reaction associated with rat colorectal tumor development
    • Lieubeau B., Gregoire M. The role of transforming growth factor β1 in the fibroblastic reaction associated with rat colorectal tumor development. Cancer Res 1994; 54: 6526-6532.
    • (1994) Cancer Res , vol.54 , pp. 6526-6532
    • Lieubeau, B.1    Gregoire, M.2
  • 94
    • 0033883776 scopus 로고    scopus 로고
    • SU 6668 is a potent antiangiogenic and antitumor agent that induces regression of established tumors
    • Laird D., Cherrington J. M. SU 6668 is a potent antiangiogenic and antitumor agent that induces regression of established tumors. Cancer Res 2000; 60: 4152-4160.
    • (2000) Cancer Res , vol.60 , pp. 4152-4160
    • Laird, D.1    Cherrington, J.M.2
  • 95
    • 0032893263 scopus 로고    scopus 로고
    • SU 5416 is a potent and selective inhibitor of the vascular endothelial growth factor (Flk-1/KDR) that inhibits tyrosine kinase catalysis, tumor vascularization and growth of multiple tumor types
    • Fong T. A., McMahon G. SU 5416 is a potent and selective inhibitor of the vascular endothelial growth factor (Flk-1/KDR) that inhibits tyrosine kinase catalysis, tumor vascularization and growth of multiple tumor types. Cancer Res 1999; 59: 99-106.
    • (1999) Cancer Res , vol.59 , pp. 99-106
    • Fong, T.A.1    McMahon, G.2
  • 96
    • 8944248812 scopus 로고    scopus 로고
    • Flk-1 as a target for tumor growth inhibition
    • Straw L. M., Shawer L. K. Flk-1 as a target for tumor growth inhibition. Cancer Res 1996; 56: 3540-3545.
    • (1996) Cancer Res , vol.56 , pp. 3540-3545
    • Straw, L.M.1    Shawer, L.K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.