-
1
-
-
0013239516
-
-
Scriver CR, Beaudet AL, Sly WS, Valle D, Stanbury JB, Wyngaarden JB, Fredrickson DS, eds. New York: McGraw-Hill
-
Foster DW 1989 In: Scriver CR, Beaudet AL, Sly WS, Valle D, Stanbury JB, Wyngaarden JB, Fredrickson DS, eds. The metabolic basis of inherited diseases. New York: McGraw-Hill; 375-397
-
(1989)
The Metabolic Basis of Inherited Diseases
, pp. 375-397
-
-
Foster, D.W.1
-
3
-
-
0030952937
-
Hypolipidemic drugs, polyunsaturated fatty, acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors α and δ
-
Forman BM, Chen J, Evans RM 1997 Hypolipidemic drugs, polyunsaturated fatty, acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors α and δ. Proc Natl Acad Sci USA 94:4312-4317
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 4312-4317
-
-
Forman, B.M.1
Chen, J.2
Evans, R.M.3
-
4
-
-
0028321529
-
Differential expression and activation of a family of murine peroxisome proliferator-activated receptors
-
Kliewer SA, Forman BM, Blumberg B, Ong ES, Borgmeyer DJ, Mangelsdorg DJ, Umesono K, Evans RM 1994 Differential expression and activation of a family of murine peroxisome proliferator-activated receptors. Proc Natl Acad Sci USA 91:7355-7359
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 7355-7359
-
-
Kliewer, S.A.1
Forman, B.M.2
Blumberg, B.3
Ong, E.S.4
Borgmeyer, D.J.5
Mangelsdorg, D.J.6
Umesono, K.7
Evans, R.M.8
-
5
-
-
0029016829
-
An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor γ (PPAR γ)
-
Lehmann JM, Moore LB, Smith-Oliver TA, Wilkinson WO, Willson TM, Kliewer SA 1995 An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor γ (PPAR γ). J Biol Chem 270:12953-12956
-
(1995)
J Biol Chem
, vol.270
, pp. 12953-12956
-
-
Lehmann, J.M.1
Moore, L.B.2
Smith-Oliver, T.A.3
Wilkinson, W.O.4
Willson, T.M.5
Kliewer, S.A.6
-
6
-
-
0028997684
-
Targeted disruption of the α isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators
-
Lee S-T, Pineau T, Drago J, Lee EJ, Owens JW, Kroetz DL, Fernandez-Salguero PM, Westphal H, Gonzalez FJ 1995 Targeted disruption of the α isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators. Mol Cell Biol 15:3012-3022
-
(1995)
Mol Cell Biol
, vol.15
, pp. 3012-3022
-
-
Lee, S.-T.1
Pineau, T.2
Drago, J.3
Lee, E.J.4
Owens, J.W.5
Kroetz, D.L.6
Fernandez-Salguero, P.M.7
Westphal, H.8
Gonzalez, F.J.9
-
7
-
-
0030766476
-
Alterations in lipoprotein metabolism in peroxisome proliferator-activated receptor α-deficient mice
-
Peters JM, Hennuyer N, Staels B, Fruchart J-C, Fievet C, Gonzalez FJ, Auwerx J 1997 Alterations in lipoprotein metabolism in peroxisome proliferator-activated receptor α-deficient mice. J Biol Chem 272:27307-27312
-
(1997)
J Biol Chem
, vol.272
, pp. 27307-27312
-
-
Peters, J.M.1
Hennuyer, N.2
Staels, B.3
Fruchart, J.-C.4
Fievet, C.5
Gonzalez, F.J.6
Auwerx, J.7
-
8
-
-
0032489437
-
Altered constitutive expression of fatty acid-metabolizing enzymes in mice lacking the peroxisome proliferator-activated receptor α (PPARα)
-
Aoyama T, Peters JM, Iritiani N, Nakajima T, Furihata K, Hashimoto T, Gonzalez FJ 1998 Altered constitutive expression of fatty acid-metabolizing enzymes in mice lacking the peroxisome proliferator-activated receptor α (PPARα). J Biol Chem 273:5678-5684
-
(1998)
J Biol Chem
, vol.273
, pp. 5678-5684
-
-
Aoyama, T.1
Peters, J.M.2
Iritiani, N.3
Nakajima, T.4
Furihata, K.5
Hashimoto, T.6
Gonzalez, F.J.7
-
9
-
-
0033625677
-
Growth, adipose, brain, and skin alterations resulting from targeted disruption of the mouse peroxisome proliferator-activated receptor β (δ)
-
Peters LM, Lee SS, Li W, Ward JM, Gavrilova O, Everett C, Reitman ML, Hudson LD, Gonzalez FJ 2000 Growth, adipose, brain, and skin alterations resulting from targeted disruption of the mouse peroxisome proliferator-activated receptor β (δ). Mol Cell Biol 20:5119-5128
-
(2000)
Mol Cell Biol
, vol.20
, pp. 5119-5128
-
-
Peters, L.M.1
Lee, S.S.2
Li, W.3
Ward, J.M.4
Gavrilova, O.5
Everett, C.6
Reitman, M.L.7
Hudson, L.D.8
Gonzalez, F.J.9
-
10
-
-
0033213637
-
PPAR γ is required for placental, cardiac, and adipose tissue development
-
Barak Y, Nelson MC, Ong ES, Jones YZ, Ruiz-Lozano P, Chien KR, Koder A, Evans RE 1999 PPAR γ is required for placental, cardiac, and adipose tissue development. Mol Cell 4:585-595
-
(1999)
Mol Cell
, vol.4
, pp. 585-595
-
-
Barak, Y.1
Nelson, M.C.2
Ong, E.S.3
Jones, Y.Z.4
Ruiz-Lozano, P.5
Chien, K.R.6
Koder, A.7
Evans, R.E.8
-
11
-
-
0033213631
-
PPAR γ is required for the differentiation of adipose tissue in vivo and in vitro
-
Rosen ED, Sarraf P, Troy AE, Bradwin G, Moore K, Milstone DS, Spiegelman BM, Mortensen RM 1999 PPAR γ is required for the differentiation of adipose tissue in vivo and in vitro. Mol Cell 4:611-617
-
(1999)
Mol Cell
, vol.4
, pp. 611-617
-
-
Rosen, E.D.1
Sarraf, P.2
Troy, A.E.3
Bradwin, G.4
Moore, K.5
Milstone, D.S.6
Spiegelman, B.M.7
Mortensen, R.M.8
-
12
-
-
0033212964
-
PPARγ mediates high-fat diet-induced adipocyte hypertrophy and insulin resistance
-
Kubota N, Terauchi Y, Miki H, Tamemoto H, Yamauchi T, Komeda K, Satoh S, Nakano R, Ishii C, Sugiyama T, Eto K, Tsubamoto Y, Okuno A, Murakami K, Sekihara H, Hasegawa G, Naito M, Toyoshima Y, Tanaka S, Shiota K, Kitamura T, Fujita T, Ezaki O, Aizawa S, Nagai R, Tobe K, Kimura S, Kadowaki T 1999 PPARγ mediates high-fat diet-induced adipocyte hypertrophy and insulin resistance. Mol Cell Biol 4:597-609
-
(1999)
Mol Cell Biol
, vol.4
, pp. 597-609
-
-
Kubota, N.1
Terauchi, Y.2
Miki, H.3
Tamemoto, H.4
Yamauchi, T.5
Komeda, K.6
Satoh, S.7
Nakano, R.8
Ishii, C.9
Sugiyama, T.10
Eto, K.11
Tsubamoto, Y.12
Okuno, A.13
Murakami, K.14
Sekihara, H.15
Hasegawa, G.16
Naito, M.17
Toyoshima, Y.18
Tanaka, S.19
Shiota, K.20
Kitamura, T.21
Fujita, T.22
Ezaki, O.23
Aizawa, S.24
Nagai, R.25
Tobe, K.26
Kimura, S.27
Kadowaki, T.28
more..
-
13
-
-
0033973843
-
Improved insulin-sensitivity in mice heterozygous for PPAR-γ deficiency
-
Miles PD, Barak Y, He W, Evans RM, Olefsky JM 2000 Improved insulin-sensitivity in mice heterozygous for PPAR-γ deficiency. J Clin Invest 105:287-292
-
(2000)
J Clin Invest
, vol.105
, pp. 287-292
-
-
Miles, P.D.1
Barak, Y.2
He, W.3
Evans, R.M.4
Olefsky, J.M.5
-
14
-
-
0034623243
-
Peroxisome proliferator-activated receptor α-mediated pathways are altered in hepatocyte-specific retinoid X receptor α-deficient mice
-
WanY-JY, Cai Y, Lungo W, Fu P, Locker J, French S, Sucov HM 2000 Peroxisome proliferator-activated receptor α-mediated pathways are altered in hepatocyte-specific retinoid X receptor α-deficient mice. J Biol Chem 275:28285-28290
-
(2000)
J Biol Chem
, vol.275
, pp. 28285-28290
-
-
Wan, Y.-J.Y.1
Cai, Y.2
Lungo, W.3
Fu, P.4
Locker, J.5
French, S.6
Sucov, H.M.7
-
15
-
-
0034035667
-
Hepatocyte-specific mutation establishes retinoid X receptor α as a heterodimeric integrator of multiple physiological processes in the liver
-
WanY-YJ, An D, Cai Y, Repa JJ, Chen HP, Flores M, Postic C, Magnuson MA, Chen J, Chien KR, French S, Mangelsdorf DJ, Sucov HM 2000 Hepatocyte-specific mutation establishes retinoid X receptor α as a heterodimeric integrator of multiple physiological processes in the liver. Mol Cell Biol 20:4436-4444
-
(2000)
Mol Cell Biol
, vol.20
, pp. 4436-4444
-
-
Wan, Y.-Y.J.1
An, D.2
Cai, Y.3
Repa, J.J.4
Chen, H.P.5
Flores, M.6
Postic, C.7
Magnuson, M.A.8
Chen, J.9
Chien, K.R.10
French, S.11
Mangelsdorf, D.J.12
Sucov, H.M.13
-
16
-
-
0023277545
-
Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
-
Chomczynski P, Sacchi N 1987 Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156-159
-
(1987)
Anal Biochem
, vol.162
, pp. 156-159
-
-
Chomczynski, P.1
Sacchi, N.2
-
17
-
-
0032491614
-
Peroxisome proliferator-activated receptor α-isoform deficiency leads to progressive dyslipidemia with sexually dimorphic obesity and steatosis
-
Costet P, Legendre C, More J, Edgar A, Galtier P, Pineau T 1998 Peroxisome proliferator-activated receptor α-isoform deficiency leads to progressive dyslipidemia with sexually dimorphic obesity and steatosis. J Biol Chem 273:29577-29585
-
(1998)
J Biol Chem
, vol.273
, pp. 29577-29585
-
-
Costet, P.1
Legendre, C.2
More, J.3
Edgar, A.4
Galtier, P.5
Pineau, T.6
-
18
-
-
0035653490
-
PPAR-α-null mice are protected from high-fat diet-induced insulin resistance
-
Guerre-Millo M, Rouault C, Poulain P, Andre J, Poitout V, Peters JM, Gonzalez FJ, Fruchart JC, Reach G, Staels B 2001 PPAR-α-null mice are protected from high-fat diet-induced insulin resistance. Diabetes 50:2809-2814
-
(2001)
Diabetes
, vol.50
, pp. 2809-2814
-
-
Guerre-Millo, M.1
Rouault, C.2
Poulain, P.3
Andre, J.4
Poitout, V.5
Peters, J.M.6
Gonzalez, F.J.7
Fruchart, J.C.8
Reach, G.9
Staels, B.10
-
19
-
-
0029995670
-
Thiazolidinediones in the treatment of insulin resistance and type II diabetes
-
Saltiel AR, Olefsky JM 1996 Thiazolidinediones in the treatment of insulin resistance and type II diabetes. Diabetes 45:1661-1669
-
(1996)
Diabetes
, vol.45
, pp. 1661-1669
-
-
Saltiel, A.R.1
Olefsky, J.M.2
-
20
-
-
0031898610
-
PPAR-γ: Adipogenic regulator and thiazolidinedione receptor
-
Spiegelman BM 1998 PPAR-γ: adipogenic regulator and thiazolidinedione receptor. Diabetes 47:507-514
-
(1998)
Diabetes
, vol.47
, pp. 507-514
-
-
Spiegelman, B.M.1
-
21
-
-
0023276184
-
Short-term metabolic effects of recombinant human insulin-like growth factor I in healthy adults
-
Guler HP, Zapf J, Froesch ER 1987 Short-term metabolic effects of recombinant human insulin-like growth factor I in healthy adults. N Engl J Med 317:137-140
-
(1987)
N Engl J Med
, vol.317
, pp. 137-140
-
-
Guler, H.P.1
Zapf, J.2
Froesch, E.R.3
-
22
-
-
0000328611
-
The IGF system
-
Rosenfeld R, Roberts Jr C, eds. Totowa, NJ: Humana Press, Inc
-
Martin JL, Baxter RC 1999 The IGF system. In: Rosenfeld R, Roberts Jr C, eds. Contemporary endocrinology. Totowa, NJ: Humana Press, Inc; 227-255
-
(1999)
Contemporary Endocrinology
, pp. 227-255
-
-
Martin, J.L.1
Baxter, R.C.2
-
23
-
-
0024916155
-
Binding proteins for the insulin-like growth factors: Structure, regulation and function
-
Baxter RC, Martin JL 1989 Binding proteins for the insulin-like growth factors: structure, regulation and function. Prog Growth Factor Res 1:49-68
-
(1989)
Prog Growth Factor Res
, vol.1
, pp. 49-68
-
-
Baxter, R.C.1
Martin, J.L.2
-
24
-
-
0028123307
-
Insulin-like growth factor-1 therapy in diabetes: Physiologic basis, clinical benefits, and risks
-
Kolaczynski JW, Caro JF 1994 Insulin-like growth factor-1 therapy in diabetes: physiologic basis, clinical benefits, and risks. Ann Intern Med 120:47-55
-
(1994)
Ann Intern Med
, vol.120
, pp. 47-55
-
-
Kolaczynski, J.W.1
Caro, J.F.2
-
25
-
-
0034002608
-
Different effects of IGF-I on insulin-stimulated glucose uptake in adipose tissue and skeletal muscle
-
Frick F, Oscarsson J, Vikman-Adolfsson K, Otosson M, Yoshida N, Eden S 2000 Different effects of IGF-I on insulin-stimulated glucose uptake in adipose tissue and skeletal muscle. Am J Physiol Endocrinol Metab 278:E729-E737
-
(2000)
Am J Physiol Endocrinol Metab
, vol.278
-
-
Frick, F.1
Oscarsson, J.2
Vikman-Adolfsson, K.3
Otosson, M.4
Yoshida, N.5
Eden, S.6
-
26
-
-
0035425234
-
Functional inactivation of the IGF-I and insulin receptors in skeletal muscle causes type 2 diabetes
-
Fernandez AM, Kim JK, Yakar S, Dupont J, Hernandez-Sanchez C, Castle AL, Filmore J, Shulman GI, Le Toith D 2001 Functional inactivation of the IGF-I and insulin receptors in skeletal muscle causes type 2 diabetes. Genes Dev 15:1926-1934
-
(2001)
Genes Dev
, vol.15
, pp. 1926-1934
-
-
Fernandez, A.M.1
Kim, J.K.2
Yakar, S.3
Dupont, J.4
Hernandez-Sanchez, C.5
Castle, A.L.6
Filmore, J.7
Shulman, G.I.8
Le Toith, D.9
|