Two Inr elements are important for mediating the activity of the proximal promoter of the human gonadotropin-releasing hormone receptor gene

Endocrinology

Volumn 144, Issue 2, 2003, Pages 518-527

  Hoo, Ruby L C ^a   Ngan, Elly S W ^a   Leung, Peter C K ^b   Chow, Billy K C ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE; GENE PRODUCT; GONADORELIN RECEPTOR; GUANINE; NUCLEAR FACTOR; NUCLEAR PROTEIN; PROTEIN INR; THYMINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; BRAIN; CONTROLLED STUDY; GEL MOBILITY SHIFT ASSAY; GENE CLUSTER; GENE CONTROL; GENE DELETION; GENE MUTATION; GENETIC ANALYSIS; GENETIC TRANSCRIPTION; HYPOPHYSIS; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN INTERACTION; PROTEIN MOTIF; RECEPTOR GENE; REGULATORY MECHANISM; SOUTHWESTERN BLOTTING;

ANIMALS; BLOTTING, SOUTHWESTERN; CELL LINE; DNA-BINDING PROTEINS; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ERYTHROID-SPECIFIC DNA-BINDING FACTORS; GENE DELETION; HUMANS; MICE; MUTAGENESIS, SITE-DIRECTED; NUCLEAR PROTEINS; PROMOTER REGIONS (GENETICS); RECEPTORS, LHRH; TRANSCRIPTION FACTOR TFIID; TRANSCRIPTION FACTORS; TRANSCRIPTION INITIATION SITE; TRANSCRIPTION, GENETIC;

EID: 0037318545     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/en.2002-220591     Document Type: Article

References (36)

1. Peng C, Fan NC, Ligier M, Vaananen J, Leung PCK 1994 Expression and regulation of gonadotropin-releasing hormone (GnRH) and GnRH receptor messenger ribonucleic acids in human granulosa-luteal cells. Endocrinology 135:1740-1746
2. Cheng KW, Nathwani PS, Leung PC 2000 Regulation of human gonadotropin-releasing hormone receptor gene expression in placental cells. Endocrinology 141:2340-2349
3. Kakar SS, Grantham K, Musgrove LC, Devor D, Sellers JC, Neill JD 1994 Rat gonadotropin-releasing hormone (GnRH) receptor: tissue expression and hormonal regulation of its mRNA. Mol Cell Endocrinol 101:151-157
4. Currie AJ, Fraser HM, Sharpe RM 1981 Human placental receptors for luteinizing hormone releasing hormone. Biochem Biophys Res Commun 99:332-338
5. Iwashita M, Evans MI, Catt KJ 1986 Characterization of a gonadotropin-releasing hormone receptor site in term placenta and chorionic villi. J Clin Endocrinol Metab 62:127-133
6. Ngan ESW, Cheng PKW, Leung PCK, Chow BKC 1999 Steroidogenic factor-1 interacts with a gonadotrope-specific element within the first exon of the human gonadotropin-releasing hormone receptor gene to mediate gonadotrope-specific expression. Endocrinology 140:2452-2462
7. Cheng KW, Ngan ESW, Kang SK, Chow BKC, Leung PCK 2000 Transcriptional down-regulation of human gonadotropin-releasing hormone (GnRH) receptor gene by GnRH: role of protein kinase C and activating protein 1. Endocrinology 141:3611-3622
8. Kang SK, Cheng KW, Ngan ESW, Chow BKC, Choi KC, Leung PCK 2000 Differential expression of human gonadotropin-releasing hormone receptor gene in pituitary and ovarian cells. Mol Cell Endocrinol 162:157-166
9. Ngan ESW, Leung PCK, Chow BKC 2000 Identification of an upstream promoter in the human gonadotropin-releasing hormone receptor gene. Biochem Biophys Res Comm 270:766-772
10. Maniatis T, Fritsch EF, Sambrook J 1989 Molecular cloning: a laboratory manual. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory
11. Chow BKC, Ting V, Tufaro F, MacGillivray RTA 1991 Characterization of a novel liver-specific enhancer in the human prothrombin gene. J Biol Chem 266:18927-18933
12. Lee KAW, Bindereif A, Green MR 1988 A small-scale procedure for preparation of nuclear extracts that support efficient transcription and pre-mRNA splicing. Gene Anal Tech 5:22-31
13. Ausubel FM, Brent R, Kingston RE, Moore DD, Seidman JG, Smith JA, Struhi K 1997 Mobility shift DNA binding assay using gel eletrophoresis. Current protocols in molecular biology. New York: J. Wiley and Sons; 12.2.1-12.2.7
14. Wieczorek E, Lin Z, Perkins EB, Law DJ, Merchant JL, Zehner ZE 2000 The zinc finger repressor, ZBP-89, binds to the silencer element of the human vimentin gene and complexes with the transcriptional activator, Sp1. J Biol Chem 275:12879-12888
15. Motulsky HJ, Searle P 1995 GraphPad Prism user's guide, version 2. San Diego, Graph-Pad Software
16. Fan NC, Peng C, Krisinger J, Leung PCK 1995 The human gonadotropin-releasing hormone receptor gene: complete structure including multiple promoters, transcription initiation sites, and polyadenylation signals. Mol Cell Endocrinol 107:R1-R8
17. Kakar SS 1997 Molecular structure of the human gonadotropin-releasing hormone receptor gene. Euro J Endocrinol 137:183-192
18. Morikawa N, Clarke TR, Novina CD, Watanabe K, Haqq C, Weiss M, Roy AL, Donahoe PK 2000 Human Mullerian-inhibiting substance promoter contains a functional TFII-I-binding initiator. Biol Reprod 63:1075-1083
19. Chalkley GE, Verrijzer CP 1999 DNA binding site selection by RNA polymerase II TAFs: a TAF(II)250-TAF(II)150 complex recognizes the initiator. EMBO J 17:4835-4845
20. Manzano-Winkler B, Novina CD, Roy AL 1996 TFII is required for transcription of the naturally TATA-less but initiator-containing Vβ promoter. J Biol Chem 271:12076-12081
21. Hariharan N, Perry RP 1990 Functional dissection of a mouse ribosomal protein promoter: significance of the polypyrimidine initiator and an element in the TATA-box region. Proc Natl Acad Sci USA 87:1526-1530
22. Javahery R, Khachi K, Lo K, Zenzie-Gregory B, Smale ST 1994 DNA sequence requirements for transcriptional initiator activity in mammalian cells. Mol Cell Biol 14:116-127
23. Lo K, Smale ST 1996 Generality of a functional initiator consensus sequence. Gene 182:13-22
24. Smale ST, Baltimore D 1989 The "initiator" as a transcription control element. Cell 57:103-113
25. Liston DR, Johnson PJ 1999 Analysis of a ubiquitous promoter element in a primitive eukaryote: early evolution of the initiator element. Mol Cell Biol 19:2380-2388
26. Gregorio ED, Chiariotti L, Nocera PPD 2001 The overlap of Inr and TATA elements sets the use of alternative transcriptional start sites in the mouse galectin-1 gene promoter. Gene 268:215-223
27. Kaufmann J, Verrijzer CP, Shao J, Smale ST 1996 CIF, an essential cofactor for TFIID-dependent initiator function. Genes Dev 10:873-886
28. Kaufmann J, Ahrens K, Koop R, Smale ST, Muller R 1998 CIF150, a human cofactor for transcription factor IID-dependent initiator function. Mol Cell Biol 18:233-239
29. Johansson E, Skogman E, Thelander L 1995 The TATA-less promoter of mouse ribonucleotide reductase R1 gene contains a TFII-I binding initiator element essential for cell cycle-regulated transcription. J Biol Chem 270:30162-30167
30. Liston DR, Lau AO, Ortiz D, Smale ST, Johnson PJ 2001 Initiator recognition in a primitive eukaryote: IBP39, an initiator-binding protein from Trichomonas vaginalis. Mol Cell Biol 21:7872-7882
31. Henzel WJ, Billeci TM, Stults JT, Wong SC, Grimley C, Watanabe C 1993 Identifying proteins from two-dimensional gels by molecular mass searching of peptide fragments in protein sequence databases. Proc Natl Acad Sci USA 90:5011-5015
32. Yan JX, Wait R, Berkelman T, Harry RA, Westbrook JA, Wheeler CH, Dunn MJ 2000 A modified silver staining protocol for visualization of proteins compatible with matrix-assisted laser desorption/ionization and electrospray ionization-mass spectrometry. Electrophoresis 21:3666-3672
33. Russek SJ, Bandopadhyay S, Farb DH 2000 An initiator element mediates autologous downregulation of the human type A γ-aminobutyric acid receptor β 1 subunit gene. Proc Natl Acad Sci USA 97:8600-8605
34. Karlen S, Braathen LR 2000 Role of the initiator element in the regulation of the melanoma cell adhesion molecule gene. J Invest Dermatol 115:668-673
35. Ngan ESW, Leung PCK, Chow BKC 2001 Interplay of pituitary adenylate cydase-activating polypeptide with a silencer element to regulate the upstream promoter of the human gonadotropin-releasing hormone receptor gene. Mol Cell Endocrinol 176:135-144
36. Verrijzer CP, Chen JL, Yokomori K, Tjian R 1995 Binding of TAFs to core elements directs promoter selectivity by RNA polymerase II. Cell 81:1115-1125