Clonal diversity among streptogramin A-resistant Staphylococcus aureus isolates collected in French hospitals

Journal of Clinical Microbiology

Volumn 41, Issue 2, 2003, Pages 586-591

  Haroche, Julien ^a   Morvan, Anne ^a   Davi, Marilyne ^a   Allignet, Jeanine ^a   Bimet, François ^a   El Solh, Névine ^a  

^a INSTITUT PASTEUR   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; DALFOPRISTIN; DALFOPRISTIN PLUS QUINUPRISTIN; GENE PRODUCT; GLYCOPEPTIDE; PRISTINAMYCIN; PROTEIN SMAI; SYNERGISTIN; UNCLASSIFIED DRUG; VERNAMYCIN; VIRGINIAMYCIN;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIUM ISOLATION; BIODIVERSITY; CELLULAR DISTRIBUTION; FRANCE; GENE ISOLATION; GENETIC SUSCEPTIBILITY; GENOTYPE; HOSPITAL CARE; HUMAN; HYBRIDIZATION; MAJOR CLINICAL STUDY; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; STAPHYLOCOCCUS AUREUS; TRANSPOSON; VATA GENE; VATB GENE; VATC GENE; VATD GENE; VATE GENE; VGAA GENE; VGAV GENE; VGBA GENE; VGBB GENE; YGAB GENE;

ANTI-BACTERIAL AGENTS; DEOXYRIBONUCLEASES, TYPE II SITE-SPECIFIC; DNA, BACTERIAL; DRUG RESISTANCE, BACTERIAL; FRANCE; GENES, BACTERIAL; HOSPITALS; HUMANS; PLASMIDS; RESTRICTION MAPPING; STAPHYLOCOCCUS AUREUS; STREPTOGRAMIN A;

BACTERIA (MICROORGANISMS); POSIBACTERIA; STAPHYLOCOCCUS AUREUS;

EID: 0037316581     PISSN: 00951137     EISSN: None     Source Type: Journal    
DOI: 10.1128/JCM.41.2.586-591.2003     Document Type: Article

References (36)

1. Allignet, J., S. Aubert, A. Morvan, and N. El Solh. 1996. Distribution of genes encoding resistance to streptogramin A and related compounds among staphylococci resistant to these antibiotics. Antimicrob. Agents Chemother. 40:2523-2528.
2. Allignet, J., and N. El Solh. 1997. Characterization of a new staphylococcal gene, vgaB, encoding a putative ABC transporter conferring resistance to streptogramin A and related compounds. Gene 202:133-138.
3. Allignet, J., and N. El Solh. 1999. Comparative analysis of staphylococcal plasmids carrying three streptogramin-resistance genes: vat-vgb-vga. Plasmid 42:134-138.
4. Allignet, J., and N. El Solh. 1995. Diversity among the gram-positive acetyltransferases inactivating streptogramin A and structurally related compounds and characterization of a new staphylococcal determinant, vatB. Antimicrob. Agents Chemother. 39:2027-2036.
5. Allignet, J., N. Liassine, and N. El Solh. 1998. Characterization of a staphylococcal plasmid related to pUB110 and carrying two novel genes, vatC and vgbB, encoding resistance to streptogramins A and B and similar antibiotics. Antimicrob. Agents Chemother. 42:1794-1798.
6. Allignet, J., V. Loncle, and N. El Solh. 1992. Sequence of a staphylococcal plasmid gene, vga, encoding a putative ATP-binding protein involved in resistance to virginiamycin A-like antibiotics. Gene 117:45-51.
7. Allignet, J., V. Loncle, P. Mazodier, and N. El Solh. 1988. Nucleotide sequence of a staphylococcal plasmid gene, vgb, encoding a hydrolase inactivating the B components of virginiamycin-like antibiotics. Plasmid 20:271-275.
8. Allignet, J., V. Loncle, C. Simenel, M. Delepierre, and N. El Solh. 1993. Sequence of a staphylococcal gene, vat, encoding an acetyltransferase inactivating the A-type compounds of virginiamycin-like antibiotics. Gene 130:91-98.
9. Aubert, S., K. G. Dyke, and N. E. Solh. 1998. Analysis of two Staphylococcus epidermidis plasmids coding for resistance to streptogramin A. Plasmid 40:238-242.
10. Barriere, J. C., N. Berthaud, D. Beyer, S. Dutka-Malen, J. M. Paris, and J. F. Desnottes. 1998. Recent developments in streptogramin research. Curr. Pharm. Des. 4:155-180.
11. Chesneau, O., A. Morvan, and N. E. Solh. 2000. Retrospective screening for heterogeneous vancomycin resistance in diverse Staphylococcus aureus clones disseminated in French hospitals. J. Antimicrob. Chemother. 45:887-890.
12. Derbise, A., S. Aubert, and N. El Solh. 1997. Mapping the regions carrying the three contiguous antibiotic resistance genes aadE, sat4, and aphA-3 in the genomes of staphylococci. Antimicrob. Agents Chemother. 41:1024-1032.
13. Derbise, A., K. G. Dyke, and N. El Solh. 1996. Characterization of a Staphylococcus aureus transposon, Tn5405, located within Tn5404 and carrying the aminoglycoside resistance genes, aphA-3 and aadE. Plasmid 35:174-188.
14. El Solh, N., and J. Allignet. 1998. Staphylococcal resistance to streptogramins and related antibiotics. Drug Resist. Updates 1:169-175.
15. El Solh, N., M. Casetta, S. Aubert, A. Morvan, and J. Allignet. 1995. Typing of methicillin-resistant Staphylococcus aureus (MRSA) based on genome analysis, p. 45-64. In C. Brun-Buisson, M. W. Casewell, N. El Solh, and B. Régnier (ed.), Methicillin-resistant staphylococci. Flammarion, Paris, France.
16. Geisel, R., F. J. Schmitz, A. C. Fluit, and H. Labischinski. 2001. Emergence, mechanism, and clinical implications of reduced glycopeptide susceptibility in Staphylococcus aureus. Eur. J. Clin. Microbiol. Infect. Dis. 20:685-697.
17. Guerin, F., A. Buu-Hoi, J. L. Mainardi, G. Kac, N. Colardelle, S. Vaupre, L. Gutmann, I. Podglajen, K. P. Koteva, D. W. Hughes, and G. D. Wright. 2000. Outbreak of methicillin-resistant Staphylococcus aureus with reduced susceptibility to glycopeptides in a Parisian hospital. J. Clin. Microbiol. 38:2985-2988.
18. Haroche, J., J. Allignet, S. Aubert, A. E. Van Den Bogaard, and N. El Solh. 2000. satG, conferring resistance to streptogramin A, is widely distributed in Enterococcus faecium strains but not in staphylococci. Antimicrob. Agents Chemother. 44:190-191.
19. Haroche, J., J. Allignet, C. Buchrieser, and N. El Solh. 2000. Characterization of a variant of vga(A) conferring resistance to streptogramin A and related compounds. Antimicrob. Agents Chemother. 44:2271-2275.
20. Haroche, J., J. Allignet, and N. El Solh. 2002. Tn5406, a new staphylococcal transposon conferring resistance to streptogramin A and related compounds, including dalfopristin. Antimicrob. Agents Chemother. 46:2337-2343.
21. Hiramatsu, K. 1998. Vancomycin resistance in staphylococci. Drug Resist. Updates 1:135-150.
22. Lepelletier, D., and Richet, H. 2001. Surveillance et contrôle des infections a Staphylococcus aureus resistants à la meticilline dans les hôpitaux français. Bull. Epidemiol. Hebd. 2001:25-27.
23. Malbruny, B., A. Canu, B. Bozdogan, B. Fantin, V. Zarrouk, S. Dutka-Malen, C. Feger, and R. Leclercq. 2002. Resistance to quinupristin-dalfopristin due to mutation of L22 ribosomal protein in Staphylococcus aureus. Antimicrob. Agents Chemother. 46:2200-2207.
24. Mukhtar, T. A., K. P. Koteva, D. W. Hughes, and G. D. Wright. 2001. Vgb from Staphylococcus aureus inactivates streptogramin B antibiotics by an elimination mechanism not hydrolysis. Biochemistry. 40:8877-8886.
25. Rende-Fournier, R., R. Leclercq, M. Galimand, J. Duval, and P. Courvalin. 1993. Identification of the satA gene encoding a streptogramin A acetyltransferase in Enterococcus faecium BM4145. Antimicrob. Agents Chemother. 37:2119-2125.
26. Ross, J. I., A. M. Farrell, E. A. Eady, J. H. Cove, and W. J. Cunliffe. 1989. Characterisation and molecular cloning of the novel macrolide-streptogramin B resistance determinant from Staphylococcus epidermidis. J. Antimicrob. Chemother. 24:851-862.
27. Singh, K. V., K. Malathum, and B. E. Murray. 2001. Disruption of an Enterococcus faecium species-specific gene, a homologue of acquired macrolide resistance genes of staphylococci, is associated with an increase in macrolide susceptibility. Antimicrob. Agents Chemother. 45:263-266.
28. Singh, K. V., G. M. Weinstock, and B. E. Murray. 2002. An Enterococcus faecalis ABC homologue (Lsa) is required for the resistance of this species to clindamycin and quinupristin-dalfopristin. Antimicrob. Agents Chemother. 46:1845-1850.
29. Soltani, M., D. Beighton, J. Philpott-Howard, and N. Woodford. 2000. Mechanisms of resistance to quinupristin-dalfopristin among isolates of Enterococcus faecium from animals, raw meat, and hospital patients in Western Europe. Antimicrob. Agents Chemother. 44:433-436.
30. Srinivasan, A., J. D. Dick, and T. M. Perl. 2002. Vancomycin resistance in staphylococci. Clin. Microbiol. Rev. 15:430-438.
31. Tenover, F. C., M. V. Lancaster, B. C. Hill, C. D. Steward, S. A. Stocker, G. A. Hancock, C. M. O'Hara, S. K. McAllister, N. C. Clark, and K. Hiramatsu. 1998. Characterization of staphylococci with reduced susceptibilities to vancomycin and other glycopeptides. J. Clin. Microbiol. 36:1020-1027.
32. Weisblum, B. 2000. Resistance to the macrolide-lincosamide-streptogramin antibiotics, p. 694-710. In V. A. Fischetti et al. (ed.), Gram-positive pathogens. ASM Press, Washington, D.C.
33. Werner, G., C. Cuny, F. J. Schmitz, and W. Witte. 2001. Methicillin-resistant, quinupristin-dalfopristin-resistant Slaphylococcus aureus with reduced sensitivity to glycopeptides. J. Clin. Microbiol. 39:3586-3590.
34. Werner, G., I. Klare, H. Heier, K. H. Hinz, G. Bohme, M. Wendt, and W. Witte. 2000. Quinupristin/dalfopristin-resistant enterococci of the satA (vatD) and satG (vatE) genotypes from different ecological origins in Germany. Microb. Drug Resist. 6:37-47.
35. Werner, G., and W. Witte. 1999. Characterization of a new enterococcal gene, satG, encoding a putative acetyltransferase conferring resistance to streptogramin A compounds. Antimicrob. Agents Chemother. 43:1813-1814.
36. Zarrouk, V., B. Bozdogan, R. Leclercq, L. Garry, C. Carbon, and B. Fantin. 2000. Influence of resistance to streptogramin A type antibiotics on the activity of quinupristin-dalfopristin in vitro and in experimental endocarditis due to Staphylococcus aureus. Antimicrob. Agents Chemother. 44:1168-1173.