Mechanisms of resistance to quinupristin-dalfopristin among isolates of Enterococcus faecium from animals, raw meat, and hospital patients in western Europe

Antimicrobial Agents and Chemotherapy

Volumn 44, Issue 2, 2000, Pages 433-436

  Soltani, Mehnam ^a,b   Beighton, David ^b   Philpott Howard, John ^b   Woodford, Neil ^a,c  

^a CENTRAL PUBLIC HEALTH LABORATORY   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c CPHL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DALFOPRISTIN PLUS QUINUPRISTIN;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GENE; BACTERIUM ISOLATE; CONTROLLED STUDY; ENTEROCOCCUS FAECIUM; GENE ISOLATION; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; STRAIN DIFFERENCE; WESTERN EUROPE;

ACETYLTRANSFERASES; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; DRUG RESISTANCE, MICROBIAL; ENTEROCOCCUS FAECIUM; EUROPE; GENES, BACTERIAL; HUMANS; MEAT; VIRGINIAMYCIN;

EID: 0033968238     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.44.2.433-436.2000     Document Type: Article

References (23)

1. Allignet, J., S. Aubert, A. Morvan, and N. El Solh. 1996. Distribution of genes encoding resistance to streptogramin A and related compounds among staphylococci resistant to these antibiotics. Antimicrob. Agents Chemother. 40:2523-2528.
2. Allignet, J., and N. El Solh. 1995. Diversity among the gram-positive acetyltransferases inactivating streptogramin A and structurally related compounds and characterizaton of a new staphylococcal determinant, vatB. Antimicrob. Agents Chemother. 39:2027-2036.
3. Allignet, J., and N. El Solh. 1997. Characterization of a new staphylococcal gene, vgaB, encoding a putative ABC transporter conferring resistance to streptogramin A and related compounds. Gene 202:133-138.
4. Allignet, J., N. Liassine, and N. El Solh. 1998. Characterization of a staphylococcal plasmid related to pUB110 and carrying two novel genes, vatC and vgbB, encoding resistance to streptogramins A and B and similar antibiotics. Antimicrob. Agents Chemother. 42:1794-1798.
5. Allignet, J., V. Loncle, and N. El Solh. 1992. Sequence of a staphylococcal plasmid gene, vga, encoding a putative ATP-binding protein involved in resistance to virginiamycin A-like antibiotics. Gene 117:45-51.
6. Allignet, J., V. Loncle, P. Mazodier, and N. El Solh. 1988. Nucleotide sequence of a staphylococcal plasmid gene, vgb, encoding a hydrolase inactivating the B components of virginiamycin-like antibiotics. Plasmid 20:271-275.
7. Allignet, J., V. Loncle, C. Simenel, M. Delepierre, and N. El Solh. 1993. Sequence of a staphylococcal gene, vat, encoding an acetyltransferase inactivating the A-type compounds of virginiamycin-like antibiotics. Gene 130: 91-98.
8. Aubert, S., K. G. H. Dyke, and N. El Solh. 1998. Analysis of two Staphylococcus epidermidis plasmids coding for resistance to streptogramin A. Plasmid 40:238-242.
9. Dever, L. L., S. M. Smith, D. Dejesus. M. Masurekar, D. Patel, Z. C. Kaminski, and J. W. G. Johanson. 1996. Treatment of vancomycin-resistant Enterococcus faecium infection with an investigational streptogramin antibiotic (quinupristin/dalfopristin): a report of fifteen cases. Microb. Drug Resist. 2:407-413.
10. El Solh, N., J. M. Fouace, Z. Shalita, D. H. Bouachaud, R. P. Novick, and Y. A. Chabbert. 1980. Epidemiological and structural studies of Staphylococcus aureus R plasmids mediating resistance to tobramycin and streptogramin. Plasmid 4:117-120.
11. Hammerum, A. M., L. B. Jensen, and F. M. Aarestrup. 1998. Detection of the satA gene and transferability of virginiamycin resistance in Enterococcus faecium from food-animals. FEMS Microbiol. Lett. 168:145-151.
12. Jensen, L. B., A. M. Hammerum, F. M. Aarestrup, A. E. Van den Bogaard, and E. E. Stobberingh. 1998. Occurrence of satA and vgb genes in streptogramin-resistant Enterococcus faecium isolates of animal and human origins in The Netherlands. Antimicrob. Agents Chemother. 42:3330-3331.
13. Jensen, L. B., N. Frimodt-Moller, and F. M. Aarestrup. 1999. Presence of erm gene classes in gram-positive bacteria of animal and human origin in Denmark. FEMS Microbiol. Lett. 170:151-158.
14. Liassine, N., J. Allignet, A. Morvan, S. Aubert, and N. El Solh. 1997. Multiplicity of the genes and plasmids conferring resistance to pristinamycin in staphylococci selected in an Algerian hospital. Zentbl. Bakteriol. 286:389-399.
15. Rende-Fournier, R., R. Leclercq, M. Galimand, J. Duval, and P. Courvalin. 1993. Identification of the satA gene encoding a streptogramin A acetyltransferase in Enterococcus faecium BM4145. Antimicrob. Agents Chemother. 37:2119-2125.
16. Roberts, M. C., J. Sutcliffe, P. Courvalin, L. B. Jensen, J. Rood, and H. Seppala. 1999. Nomenclature for macrolide and macrolide-lincosamide-streptogramin B antibiotic resistance determinants. Antimicrob. Agents Chemother. 43:2823-2830.
17. Sahgal, V. S., C. Urban, N. Mariano, F. Weinbaum, J. Turner, and J. J. Rahal. 1995. Quinupristin/dalfopristin (RP59500) therapy for vancomycin-resistant Enterococcus faecium aortic graft infection: case report. Microb. Drug Resist. 1:245-247.
18. Wade, J., L. Baillie, N. Rolando, and M. Casewell. 1992. Pristinamycin for Enterococcus faecium resistant to vancomycin and gentamicin. Lancet 339: 312-313.
19. Werner, G., I. Klare, and W. Witte. 1998. Association between quinupristin/ dalfopristin resistance in glycopeptide-resistant Enterococcus faecium and the use of additives in animal feed. Eur. J. Clin. Microbiol. Infect. Dis. 17:401-402.
20. Werner, G., and W. Witte. 1999. Characterization of a new enterococcal gene, satG, encoding a putative acetyltransferase conferring resistance to streptogramin A compounds. Antimicrob. Agents Chemother. 43:1813-1814.
21. Woodford, N. 1998. Glycopeptide-resistant enterococci: a decade of experience. J. Med. Microbiol. 47:849-862.
22. Woodford, N., D. Morrison, B. Cookson, and R. C. George. 1993. Comparison of high-level gentamicin-resistant Enterococcus faecium isolates from different continents. Antimicrob. Agents Chemother. 37:681-684.
23. Woodford, N., M. F. Palepou, A. P. Johnson, P. R. Chadwick, and J. Bates. 1997. Methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci. Lancet 350:737-738.