The general regulatory factor Reb1p controls basal, but not Gal4p-mediated, transcription of the GCY1 gene in yeast

Molecular and General Genetics

Volumn 256, Issue 6, 1997, Pages 682-689

  Angermayr, M ^a   Bandlow, W ^a  

^a UNIVERSITY OF MUNICH   (Germany)

Author keywords

Basal transcription; Gal4 protein; General regulatory factors; Saccharomyces cerevisiae

Indexed keywords

ARTICLE; DNA STRUCTURE; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; SACCHAROMYCES CEREVISIAE; TATA BOX; TRANSCRIPTION REGULATION; YEAST;

BINDING SITES; DNA-BINDING PROTEINS; FUNGAL PROTEINS; GTP-BINDING PROTEINS; PROMOTER REGIONS (GENETICS); RAP GTP-BINDING PROTEINS; RECOMBINANT FUSION PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE DELETION; SUGAR ALCOHOL DEHYDROGENASES; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 0030699322     PISSN: 00268925     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004380050616     Document Type: Article

References (31)

1. Achstetter T, Ehmann C, Osaki A, Wolf DH (1984) Proteolysis in eukaryotic cells. J Biol Chem 259:13344-13348
2. Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein dye binding. Analyt Biochem Res 72:248-254
3. Bram RJ, Kornberg RD (1987) Isolation of a S. cerevisiae centromere DNA-binding protein, its human homolog, and its possible role as a transcription factor. Mol Cell Biol 7:403-409
4. Brandi CJ, Struhl K (1990) A nucleosome-positioning sequence is required for GCN4 to activate transcription in the absence of a TATA element. Mol Cell Biol 10:4256-4265
5. Buchman AR, Kimmerly WJ, Rinc J, Kornberg RD (1988) Two DNA-binding factors recognize specific sequences at silencers, upstream activating sequences, autonomously replicating sequences, and telomeres in Saccharomyces cerevisiae. Mol Cell Biol 8:210-225
6. G, and functions as a powerful auxiliary gene activator. Genes Dev 4:503-514
7. 2-cytochrome c reductase. J Biol Chem 263:14323-14333
8. Dorsman JC, van Heeswijk WC, Grivell LA (1988) Identification of two factors which bind to the upstream sequences of a number of nuclear genes coding for mitochondrial proteins and to genetic elements important for cell division in yeast. Nucleic Acids Res 16:7287-7301
9. Dorsman JC, Doorenbosch MM, Maurer CTC, de Winde JH, Mager WH, Planta RJ, Grivell LA (1989) An ARS silencer binding factor also activates two ribosomal protein genes in yeast. Nucleic Acids Res 17:4917-4923
10. Fedor MJ, Luc NF, Kornberg RD (1988) Statistical positioning of nucleosomes by specific protein-binding to an upstream activating sequence in yeast. J Mol Biol 204:109-127
11. Gonçalves PM, Griffioen G, Minnee R, Bosnia M, Kraakman LS, Mager WH, Planta RJ (1995) Transcription activation of yeast ribosomal protein genes requires additional elements apart from binding sites for Abf1p and Rap1p. Nucleic Acids Res 23:1475-1480
12. Graham IR, Chambers A (1994) A Reb1p-binding site is required for efficient activation of the yeast RAP1 gene, but multiple binding sites for Rap1p are not essential. Mol Microbiol 12:931-940
13. Guarente L (1983) Yeast promoters and lacZ fusions designed to study expression of cloned genes in yeast. Methods Enzymol 101:181-191
14. Hermann H, Häcker U, Bandlow W, Magdolen V (1992) pYLZ vectors: Succharomyces cerevisiae Escherichia coli shuttle plasmids to analyze yeast promoters. Gene 119:137-141
15. Keszenman-Pereyra D, Hieda K (1988) A colony procedure for transformation of S. cerevisiae. Curr Genet 13: 21-23
16. Kunkel TA (1985) Rapid and site-specific mutagenesis without phenotypic selection. Proc Natl Acad Sci USA 82:488-492
17. Kunkel TA, Roberts JD, Zakour RA (1987) Rapid and efficient site-specific mutagenesis without phenotypic selection. Methods Enzymol 154:367-382
18. Lang WH, Reeder RH (1993) The REB1 site is an essential component of a terminator for RNA polymerase I in Saccharomyces cerevisiae. Mol Cell Biol 13: 649-658
19. Lohr D (1993) Chromatin structure and regulation of the eukaryotic regulatory gene GAL80. Proc Natl Acad Sci USA 90:10628-10632
20. Lohr D, Hopper JE (1985) The relationship of regulatory proteins and DNaseI hypersensitive sites in the yeast GAL1-10 genes. Nucleic Acids Res 13:8409-8423
21. Magdolen V, Oechsner U, Trommler P, Bandlow W (1990) Transcriptional control by galactose of a yeast gene encoding a protein homologous to mammalian aldo keto reductases. Gene 90:105-114
22. Maniatis T, Fritsch EF, Sambrook J (1982) Molecular cloning a laboratory manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York
23. McLean M, Hubberstey AV, Bouman DJ, Pece N, Mastrangelo P, Wildeman AG (1995) Organization of the Saccharomyces cerevisiae actin gene USA: functional significance of reiterated REB1 binding sites and AT-rich elements. Mol Microbiol 18:605-614
24. Mellor J, Jiang W, Funk M, Rathjen J, Barnes CA, Hinz T, Hegemann JH, Philippsen P (1990) CPFI, a yeast protein which functions in centromeres and promoters. EMBO J 9:4017-4026
25. Morrow BE, Johnson SP, Warner JR (1989) Proteins that bind to the yeast rDNA enhancer. J Biol Chem 264:9061-9068
26. Morrow BE, Ju Q, Warner JR (1993) A bipartite DNA-binding domain in yeast Reb1p. Mol Cell Biol 13:1173-1182
27. Oechsner U, Bandlow W (1996) Interactions of the yeast centromere and promoter factor, Cpf1p, with the cytochrome cj upstream region and functional implications on regulated gene expression. Nucleic Acids Res 24:2395-2403
28. Packham EA, Graham IR, Chambers A (1996) The multifunctional transcription factors Abf1p, Rap1p and Reb1p are required for full transcriptional activation of the chromosomal PGK gene in Saccharomyces cerevisiae. Mol Gen Genet 250: 348-356
29. Remacle JE, Holmberg S (1992) A REB1-binding site is required for GCN4-independent ILVl basal level transcription and can be functionally replaced by an ABF1-binding site. Mol Cell Biol 12:5516-5526
30. Scott EW, Baker HV (1993) Concerted action of the transcriptional activators REB1, RAP1 and GCR1 in the high-level expression of the glycolytic gene TPI. Mol Cell Biol 13:543-550
31. Shore D, Nasmyth K (1987) Purification and cloning of a DNA binding protein that binds two both silencer and activator elements Cell 51:721-732