Common surface-antigen var genes of limited diversity expressed by Plasmodium falciparum placental isolates separated by time and space

Journal of Infectious Diseases

Volumn 187, Issue 3, 2003, Pages 477-483

  Khattab, Ayman ^a   Kremsner, Peter G ^a,b   Klinkert, Mo Quen ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b ALBERT SCHWEITZER HOSPITAL   (Gabon)

Author keywords

[No Author keywords available]

Indexed keywords

CHONDROITIN SULFATE; MEMBRANE ANTIGEN; PROTEIN; PROTEIN VAR; QUININE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; BLOOD GROUP DUFFY SYSTEM; CAMEROON; CONTROLLED STUDY; DISEASE ASSOCIATION; DNA SEQUENCE; DNA TRANSCRIPTION; FEMALE; GABON; GENE; GENETIC CODE; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALARIA FALCIPARUM; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PLACENTA; PLASMODIUM FALCIPARUM; PREGNANCY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN STRUCTURE; RECEPTOR BINDING; SEQUENCE HOMOLOGY; TIME; VACCINE PRODUCTION; VAR GENE;

ANIMALS; ANTIGENS, SURFACE; CAMEROON; FEMALE; GABON; GENE EXPRESSION REGULATION; GENES, PROTOZOAN; HUMANS; MOLECULAR SEQUENCE DATA; PHYLOGENY; PLACENTA; PLASMODIUM FALCIPARUM; PREGNANCY; PREGNANCY COMPLICATIONS, INFECTIOUS; TIME FACTORS; VARIATION (GENETICS);

EID: 0037312462     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/368266     Document Type: Article

References (20)

1. Brabin BJ. An analysis of malaria in pregnancy in Africa. Bull World Health Organ 1983; 61:1005-16.
2. Fried M, Duffy PE. Adherence of Plasmodium falciparum to chondroitin sulfate A in the human placenta. Science 1996; 272:1502-4.
3. Buffet PA, Gamain B, Scheidig C, et al. Plasmodium falciparum domain mediating adhesion to chondroitin sulfate A: a receptor for human placental infection. Proc Natl Acad Sci USA 1999; 96:12743-8.
4. Reeder JC, Cowman AF, Davern KM, et al. The adhesion of Plasmodium falciparum - infected erythrocytes to chondroitin sulfate A is mediated by P. falciparum erythrocyte membrane protein 1. Proc Natl Acad Sci USA 1999; 96:5198-202.
5. Khattab A, Kun J, Deloron P, Kremsner PG, Klinkert MQ. Variants of Plasmodium falciparum erythrocyte membrane protein 1 expressed by different placental parasites are closely related and adhere to chondroitin sulfate A. J Infect Dis 2001; 183:1165-9.
6. Beeson JG, Rogerson SJ, Cooke BM, et al. Adhesion of Plasmodium falciparum - infected erythrocytes to hyaluronic acid in placental malaria. Nat Med 2000; 6:86-90.
7. Flick K, Scholander C, Chen Q, et al. Role of nonimmune IgG bound to PfEMP1 in placental malaria. Science 2001; 293:2098-100.
8. Fried M, Nosten F, Brockman A, Brabin BJ, Duffy PE. Maternal antibodies block malaria. Nature 1998; 395:851-2.
9. Ricke CH, Staalsoe T, Koram K, et al. Plasma antibodies from malaria-exposed pregnant women recognize variant surface antigens on Plasmodium falciparum - infected erythrocytes in a parity-dependent manner and block parasite adhesion to chondroitin sulfate A. J Immunol 2000; 165:3309-16.
10. Vazquez-Macias A, Martinez-Cruz P, Castaneda-Patlan MC, et al. A distinct 5′ flanking var gene region regulates Plasmodium falciparum variant erythrocyte surface antigen expression in placental malaria. Mol Microbiol 2002; 45:155-67.
11. Sylla EH, Kun JF, Kremsner PG. Mosquito distribution and entomological inoculation rates in three malaria-endemic areas in Gabon. Trans R Soc Trop Med Hyg 2000; 94:652-6.
12. Kassberger F, Birkenmaier A, Khattab A, Kremsner PG, Klinkert MQ. PCR typing of Plasmodium falciparum in matched peripheral, placental and umbilical cord blood. Parasitol Res 2002; 88:1073-9.
13. Planche T, Krishna S, Kombila M, et al. Comparison of methods for the rapid laboratory assessment of children with malaria. Am J Trop Med Hyg 2001; 65:599-602.
14. Taylor HM, Kyes SA, Harris D, Kriek N, Newbold CI. A study of var gene transcription in vitro using universal var gene primers. Mol Biochem Parasitol 2000; 105:13-23.
15. Contamin H, Fandeur T, Bonnefoy S, Skouri F, Ntoumi F, Mercereau-Puijalon O. PCR typing of field isolates of Plasmodium falciparum. J Clin Microbiol 1995; 33:944-51.
16. Peterson DS, Miller LH, Wellems TE. Isolation of multiple sequences from the Plasmodium falciparum genome that encode conserved domains homologous to those in erythrocyte-binding proteins. Proc Natl Acad Sci USA 1995; 92:7100-4.
17. Beeson JG, Brown GV, Molyneux ME, Mhango C, Dzinjalamala F, Rogerson SJ. Plasmodium falciparum isolates from infected pregnant women and children are associated with distinct adhesive and antigenic properties. J Infect Dis 1999; 180:464-72.
18. Rowe JA, Kyes SA, Rogerson SJ, Babiker HA, Raza A. Identification of a conserved Plasmodium falciparum var gene implicated in malaria in pregnancy. J Infect Dis 2002; 185:1207-11.
19. Fried M, Duffy PE. Two DBL-γ subtypes are commonly expressed by placental isolates of Plasmodium falciparum. Mol Biochem Parasitol 2002; 122:201-10.
20. Gamain B, Gratepanche S, Miller LH, Baruch DI. Molecular basis for the dichotomy in Plasmodium falciparum adhesion to CD36 and chondroitin sulfate A. Proc Natl Acad Sci USA 2002; 99:10020-4.