Inhibition of Ostwald ripening in local anesthetic emulsions by using hydrophobic excipients in the disperse phase

International Journal of Pharmaceutics

Volumn 200, Issue 2, 2000, Pages 249-260

  Welin Berger, Katayoun ^a   Bergenståhl, Björn ^b  

^a ASTRAZENECA R AND D   (Sweden)

^b LUND UNIVERSITY   (Sweden)

Author keywords

Local anesthetics; Ostwald ripening; Ripening inhibitors; Submicron emulsion stability

Indexed keywords

2 OCTYLDODECANOL; EXCIPIENT; LIDOCAINE; LIQUID PARAFFIN; LOCAL ANESTHETIC AGENT; MIGLYOL; PRILOCAINE; TRIACYLGLYCEROL;

ARTICLE; DIFFUSION COEFFICIENT; DRUG STABILITY; EMULSION; PRIORITY JOURNAL; SOLUBILITY;

ANESTHETICS, LOCAL; DIFFUSION; EMULSIONS; EXCIPIENTS; KINETICS; LIDOCAINE; MODELS, CHEMICAL; PARTICLE SIZE; PRILOCAINE; SOLUBILITY;

EID: 0034630962     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(00)00395-1     Document Type: Article

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