In vitro permeation profile of a local anaesthetic compound from topical formulations with different rheological behaviour - Verified by in vivo efficacy data

European Journal of Pharmaceutical Sciences

Volumn 14, Issue 3, 2001, Pages 229-236

  Welin Berger, Katayoun ^a   Neelissen, Jan ^a   Bergenståhl, Björn ^b  

^a ASTRAZENECA R AND D   (Sweden)

^b LUND UNIVERSITY   (Sweden)

Author keywords

Permeation rate; Rheological behaviour; Topical formulation; W O emulsion, O W emulsion

Indexed keywords

CELLS; DIFFUSION; EMULSIONS; MEMBRANES; RHEOLOGY; YIELD STRESS;

PERMEATION PROFILES;

ANESTHETICS;

ANALGESIC AGENT; CARBOMER; LOCAL ANESTHETIC AGENT; WATER OIL CREAM;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CREAM; DRUG FORMULATION; EMULSION; FLOW KINETICS; GUINEA PIG; HUMAN; HUMAN TISSUE; IN VITRO STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; SKIN PERMEABILITY; TOPICAL DRUG ADMINISTRATION; VISCOSITY;

ADMINISTRATION, TOPICAL; ANESTHETICS, LOCAL; ANIMALS; CHEMISTRY, PHARMACEUTICAL; EMULSIONS; GUINEA PIGS; MALE; RHEOLOGY; SKIN ABSORPTION;

EID: 0034830176     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0928-0987(01)00181-6     Document Type: Article

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