Association between the A2 allele of the HLA system and age at onset of Alzheimer's disease;Association entre allèle A2 du système HLA et âge de début de la maladie d'Alzheimer

Presse Medicale

Volumn 32, Issue 4, 2003, Pages 158-161

  Nourhashemi F ^a   Gillette Guyonnet, S ^a   Fort, M ^a   Andrieu, S ^a   Abbal, M ^a   Albarede J L ^a   Vellas, B ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN E4; HLA A2 ANTIGEN;

ADULT; AGED; AGING; ALLELE; ALZHEIMER DISEASE; ARTICLE; CAUCASIAN; DEGENERATIVE DISEASE; DISEASE ASSOCIATION; FEMALE; HLA SYSTEM; HUMAN; MAJOR CLINICAL STUDY; MALE; NEUROLOGIC DISEASE; ONSET AGE;

EID: 0037309392     PISSN: 07554982     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Cruts M, Van Duijn CM, Backhovens H et al. Estimation of the genetic contribution of presenilin-1 and -2 mutations in a population-based study of presenile Alzheimer disease. Hum Mol Genet 1998; 7: 43-51.
2. Rogaev EI, Sherrington R, Rogaeva EA et al. Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene. Nature 1995; 376: 775-8.
3. Goates A, Chartier-Harlin MC, Mullah M et al. Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease. Nature 1991; 349: 704-6.
4. Strittmatter WJ, Saunders AM, Schmechel D et al. Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. Proc Natl Acad Sci USA 1993; 90: 1977-81.
5. Farrer LA, Cupples LA, Haines JL et al. Effects of age, sex, and ethnicity on the the association between Apolipoprotein E genotype and Alzheimer disease. A metaanalysis. JAMA 1997; 278: 1349-56.
6. Corder EH, Saunders AM, Strittmatter WJ et al. Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. Science 1993; 261: 921-3.
7. McGeer PL, Schulzer M, McGeer EG. Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer's disease: a review of 17 epidemiologic studies. Neurology 1996; 47: 425-32.
8. Harris JM, Cumming AM, Craddock N, StClair D, Lendon CL. Human leucocyte antigen-A2 increases risk of Alzheimer's disease but does not affect age of onset in a scottish population. Neurosci Lett 2000; 294: 37-40.
9. Small GW, Scott WK, Komo S et al. No association between the HLA-A2 allele and Alzheimer disease. Neurogenetics 1999; 2: 177-82.
10. Payami H, Schellenberg GD, Zareparsi S et al. Evidence for association of HLA-A2 allele with onset age of Alzheimer's disease. Neurology 1997; 49: 512-18.
11. Small GW, Ebeling SC, Matsuyama SS et al. Variable association of HLA-A2 in Men with early onset Alzheimer disease. Neurobiol Aging 1991; 12: 375-7.
12. Payami H, Kaye J, Becker W, Norman B, Wetzsteon P. HLA-A2 or a closely linked gene, confers susceptibility to early-onset sporadic Alzheimer's disease in men. Neurology 1991; 41: 1544-8.
13. Small GW, Matsuyama SS. HLA-A2 as a possible marker for early-onset Alzheimer disease in men. Neurobiol Aging 1986; 7: 211-14.
14. Combarros O, Escribano J, Sanchez-Valasco P et al. Association of the HLA-A2 allele with an earlier age of onset of Alzheimer's disease. Acta Neurol Scand 1998; 98: 140-1.
15. Ballerini C, Nacmias B, Rombola G, Marcon G, Massacesi L, Sorbi S. HLA-A2 allele is associated with age at onset of Alzheimer's disease. Ann Neurol 1999; 45: 397-400.
16. McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 1984; 34: 939-44.
17. American Psychiatric Association: Diagnostic and Statistical Manual of Mental Disorders, 4th ed. Washington, DC, American Psychiatric Association, 1994.
18. Hixson JE, Vernier DT. Restriction isotyping of human apolipoprotein E by gene amplification and cleavage Hhal. J Lipid Res 1990; 31: 545-8.
19. Fernandez-Vina MA, Falco M, Sun Y, Stastny P. DNA typing for HLA class I alleles: Subsets of HLA-A2 and of A-28. Hum Immunol 1992; 33: 163-73.
20. Tol J, Roks G, Slooter AJC, Van Duijn CM. Genetic and environmental factors in Alzheimer's disease. Rev Neurol 1999; 155: 4510-11.
21. Farrer LA, Cupples LA, Haines JL et al. Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A metaanalysis. APOE and Alzheimer Disease Meta Analysis Consortium. JAMA 1997; 278: 1349-56.
22. Alzheimer's Disease Collaborative Group. Apolipoprotein E genotype and Alzheimer's disease. Lancet 1993; 48: 1034-50.
23. Parham P, Ohta T. Population biology of antigen presentation by MHC class I molecules. Science 1996; 272: 67-74.
24. Imanishi T, Akaza T, Kimura A, Tokunga K, Gojobori T. Allele and haplotype frequencies for HLA and complement loci in various ethnic groups. HLA 1991: Proceedings of the Eleventh International Histocompatibility Workshop and conference. Oxford: Oxford University Press, 1992: 1065-1220.
25. Lagaay A, D'Amaro J, Ligthart G, Schreuder G, van Rood J, Hijmans W. Longevity and heredity in humans. Associations with human leukocyte antigens phenotype. Ann NY Acad Sci 1991; 621: 78-89.
26. Cagnin A, Brooks DJ, Kennedy AM et al. In-vivo measurment of activated microglia in dementia. Lancet 2001; 358: 461-7.
27. Van Gool WA, Weinstein HC, Scheltens P, Walstra GI, Scheltens PK. Effect of hydroxychloroquine on progression of dementia in early Alzheimer's disease: an 18-month randomised, double-blind, placebo-controlled study. Lancet 2001; 358: 455-60.