Prolonged perinatal AZT administration and early maternal separation: Effects on social and emotional behaviour of periadolescent mice

Pharmacology Biochemistry and Behavior

Volumn 74, Issue 3, 2003, Pages 671-681

  Venerosi, Aldina ^a   Cirulli, Francesca ^a   Capone, Francesca ^a   Alleva, Enrico ^a  

^a ISTITUTO SUPERIORE DI SANITÀ   (Italy)

Author keywords

AZT; Behavioural teratology; Corticosterone; Maternal deprivation; Mouse; Plus maze; Social behaviour

Indexed keywords

ZIDOVUDINE;

AGGRESSION; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; DELIVERY; EMOTIONALITY; EXPLORATORY BEHAVIOR; FEMALE; GENDER; LACTATION; MALE; MATERNAL DEPRIVATION; MAZE TEST; MOTHER CHILD RELATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROGENY; RISK ASSESSMENT; SOCIAL BEHAVIOR; STRESS;

ANIMALIA; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0037304327     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-3057(02)01068-7     Document Type: Article

References (43)

1. Altman J. Observational study of behaviour: sampling methods. Behaviour. 49:1974;277-285.
2. Applewhite-Black L.E., Dow-Edwards D.L., Minkoff H.L. Neurobehavioural and pregnancy effects of prenatal zidovudine exposure in Sprague-Dawley rats: preliminary findings. Neurotoxicol. Teratol. 20:1998;251-258.
3. Blanche S., Tardieu M., Rustin P., Slama A., Barret B., Firtion G.et al. Persistent mitochondrial dysfunction and perinatal exposure to antiretroviral nucleoside analogues. Lancet. 354:1999;1084-1089.
4. Blum R.M., Liao S.H.T., Good S.S., de Miranda P. Pharmacokinetics and bioavailability of zidovudine in humans. Am. J. Med. 85:1988;189-194.
5. Busidan Y., Dow-Edwards D. Neurobehavioral effects of perinatal AZT exposure in Sprague-Dawley weaning rats. Pharmacol. Biochem. Behav. 64:1999;479-485.
6. Calamandrei G., Venerosi A., Branchi I., Chiarotti F., Verdina A., Bucci F.et al. Effects of prenatal AZT on mouse neurobehavioural development and passive avoidance learning. Neurotoxicol. Teratol. 21:1999;29-40.
7. Public Health Service Task Force recommendations for the use of antiretroviral drugs in pregnant women infected with HIV-1 for maternal health and for reducing perinatal transmission in the United States. MMWR. 47:1998;1-28.
8. Cirulli F. Role of environmental factors on brain development and nerve growth factor expression. Physiol. Behav. 73:2001;321-330.
9. Cirulli F., Adriani W., Laviola G. Sexual segregation in infant mice: behavioural and neuroendocrine responses to D-amphetamine administration. Psychopharmacology. 134:1997;140-152.
10. Clausing P., Mothes H.K., Opitz B. Preweaning experience as a modifier of prenatal drug effects in rats and mice: a review. Neurotoxicol. Teratol. 22:2000;113-123.
11. Connor E.M., Sperling R.S., Gelber R., Kiselev P., Scott G., O'Sullivan M.J.et al. Reduction of maternal-infant transmission of human immunodeficiency virus type 1 with zidovudine treatment. N. Engl. J. Med. 331:1994;1173-1180.
12. Ellis L. Social status and health in humans: the nature of the relations and its possible causes. Ellis L. Social stratification and socioeconomic inequality. vol. 2:1994;Praeger Publishers, London.
13. File S.E. Behavioural detection of anxiolitic action. Elliot J.M., Mardsen C.A. Experimental approaches to anxiety and depression. 1992;25-44 Wiley, Chichester.
14. File S.E. The interplay of learning and anxiety in the elevated plus-maze. Behav. Brain Res. 58:1993;199-202.
15. Risk of early febrile seizure with perinatal exposure to nucleoside analogues. Lancet. 359:2002;583-584.
16. Gerschenson M., Erhart S.W., Paik C.Y., St.Claire M.C., Nagashima K., Skopets B.et al. Fetal mitochondrial heart and skeletal muscle damage in Eritrocebus patas monkeys exposed in utero to 3′-azido-3′deoxythymidine. AIDS Res. Hum. Retrovir. 16:2000;634-644.
17. Gibb D.M., Beatriz H.Y. Interventions to reduce mother-to-child transmission of HIV infection: new developments and current controversies. AIDS. 13:1999;S93-S102.
18. Grant E.C., Mackintosh J.H. A comparison of the social postures of some common laboratory rodents. Behaviour. 21:1963;246-259.
19. Ha J.C., Nobisch C., Abkowitz J.L., Conrad S.H., Mottet N.K., Ruppenthal G.C.et al. Fetal, infant, and maternal toxicity of zidovudine (azidothymidine) administered throughout pregnancy in Macaca nemestrina. J. Acquir. Immune Defic. Syndr. 18:1998;27-38.
20. Harkness S., Super C.M. The developmental niche: a theoretical framework for analyzing the household production of health. Soc. Sci. Med. 38:1994;217-226.
21. Kaiser S., Sachser N. Social stress during pregnancy and lactation affects in guinea pigs the male offsprings' endocrine status and infantilizes their behaviour. Psychoneuroendocrinology. 26:2001;503-519.
22. Lehmann J., Pryce C.R., Jongen-Rêlo Al., Stöhr T., Pothuizen H.H.J., Feldon J. Comparison of maternal separation and early handling in terms of their neurobehavioral effects in aged rats. Neurobiol. Aging. 23:2002;457-466.
23. Levine S. Infantile experience and resistance to physiological stress. Science. 126:1957;405-406.
24. Levine S., Broadhurst P.L. Genetic and ontogenetic determinants of adult behavior in the rat. J. Comp. Physiol. Psychol. 56:1963;423-428.
25. Lister R.G. The use of a plus-maze to measure anxiety in the mouse. Psychopharmacology. 92:1987;180-185.
26. Meaney M. Maternal care, gene expression, and the transmission of individual differences in stress reactivity across generations. Ann. Rev. Neurosci. 24:2001;1161-1192.
27. Meaney M.J., Mitchell J.B., Aitken D.H., Bhatnagar S., Bodnoff S.R., Iny L.J.et al. The effects of neonatal handling on the development of the adrenocortical response to stress: implications for neuropathology and cognitive deficits in later life. Psychoneuroendocrinology. 16:1991;85-103.
28. Mofenson L.M., McIntyre J.A. Advances and research directions in the prevention of mother-to-child transmission. Lancet. 355:2000;2237-2244.
29. Noldus L.P.J.J. The observer: a software system for collection and analysis of observational data. Behav. Res. Meth. Instrum. Comput. 23:1991;415-429.
30. Pellow S., Chopin P., File S.E., Briley M. Validation of the open: closed arm entries in an elevated plus-maze as a measure of anxiety in the rat. J. Neurosci. Methods. 14:1985;149-167.
31. Nucleoside exposure in the children of HIV-infected women receiving antiretroviral drugs: absence of clear evidence for mitochondrial disease in children who died before 5 years of age in five United States cohorts. J. Acquir. Immune Defic. Syndr. 25:2000;261-268.
32. Plotsky P.M., Meaney M.J. Early, postnatal experience alters hypothalamic corticotropin-releasing factor (CRF) mRNA, median eminence CRF content and stress-induced release in adult rats. Mol. Brain Res. 18:1993;195-200.
33. Rodgers R.J., Johnson N.J. Factor analysis of spatiotemporal and ethological measures in the murine elevated plus-maze test of anxiety. Pharmacol. Biochem. Behav. 52:1995;297-303.
34. Rondinini C., Venerosi A., Branchi I., Calamandrei G., Alleva E. Long-term effects of prenatal 3′-azido-3′-deoxythymidine (AZT) exposure on intermale aggressive behaviour of mice. Psychopharmacology. 107:1999;1-7.
35. Slikker W. Jr., Olivero O.A., Patterson T.A., Poirier M.C. Potential toxicities of HIV therapeutics in the developing infant. Teratology. 61:2000;397-398.
36. Spear L.P. The adolescent brain and age-related behavioral manifestations. Neurosci. Biobehav. Rev. 24:2000;417-463.
37. Terranova M.L., Laviola G., Alleva E. Ontogeny of amicable social behaviour in mouse: gender differences and on-going isolation outcomes. Dev. Psychobiol. 26:1993;467-481.
38. Terranova M.L., Laviola G., de Acetis L., Alleva E. A description of the ontogeny of mouse agonistic behavior. J. Comp. Psychol. 112:1998;3-12.
39. Terranova M.L., Cirulli F., Laviola G. Behavioral and hormonal effects of partner familiarity in periadolescent rat pairs upon novelty exposure. Psychoneuroendocrinology. 24:1999;639-656.
40. Tronick E.Z., Beeghly M. Prenatal cocaine exposure, child development, and the compromising effects of cumulative risk. Clin. Perinatol. 26:1999;151-171.
41. Venerosi A., Cirulli F., Fiore M., Lil'p I.G., Calamandrei G., Alleva E. Prolonged perinatal exposure to AZT affects aggressive behavior of adult CD-1 mice. Psychopharmacology. 150:2000;404-411.
42. Venerosi A., Valanzano A., Alleva E., Calamandrei G. Prenatal exposure to anti-HIV drugs: neurobehavioral effects of zidovudine (AZT)+lamivudine (3TC) treatment in mice. Teratology. 63:2001;26-37.
43. Wilcox R.R. New statistical procedures for the social sciences. Modern solutions to basic problems. 1987;Lawrence Erlbaum, Hillsdale, NJ.